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11

Urinary Tract

■ Wall Changes

Diffuse Wall Thickening

Tract

 

 

Malformations

 

 

 

 

 

 

Dilated Renal Pelvis and Ureter

 

 

 

 

 

 

Renal Pelvic Mass, Ureteral Mass

Urinary

 

 

 

 

Changes in Bladder Size or Shape

 

 

 

 

 

 

Intracavitary Mass

 

 

 

 

 

 

Wall Changes

 

 

 

 

 

Diffuse Wall Thickening

 

 

 

Circumscribed Wall Thickening

 

 

 

Concavities and Convexities

Bladder-Wall Hypertrophy

Flat Bladder Tumor

Bladder-WallHypertrophy

The normal wall thickness of a distended blad-

inflammations (e. g., after prolonged catheter-

distension may be misinterpreted as diffuse

der is 1–3 mm and does not exceed 5 mm

ization) or schistosomiasis in some regions, but

wall thickening (Fig.11.94). In children, ure-

(Fig.11.91).

it most commonly results from infravesical ob-

thral valves may also cause wall thickening

Diffuse bladder-wall hypertrophy greater

struction, often combined with pseudodiverti-

and urinary stasis by subvesical stenosis.

than 5 mm may be found in association with

cula (Fig.11.92, Fig.11.93). Inadequate bladder

 

Fig. 11.91 Normal three-layered wall (cursors) of a welldistended bladder (HB).

Fig. 11.92 Diffuse bladder-wall thickening secondary to an infravesical prostatic obstruction.

a Bladder-wall thickening without a pseudodiverticulum (cursors).

b Diffuse wall thickening with pseudodiverticulum (arrows). DK = echogenic indwelling catheter.

Fig. 11.93 Massive wall thickening, measuring up to 20 mm at some sites and exceeding the wall thickness of an empty bladder (compare with Fig. 11.94). IC = indwelling catheter. FL = urinary fluid.

f Fig. 11.94 Apparent diffuse wall thickening (cursors) in a partially distended bladder (HB).

410

Flat Bladder Tumor

It can be difficult or impossible to distinguish diffuse bladder-wall hypertrophy from a carcinoma, sarcoma, or lymphoma that has formed a plaque-like growth on the bladder wall.

If ultrasound raises suspicion of a flat carcinoma on the bladder wall, further tests such as cystoscopy, radiography, and CT should be carried out (Fig.11.95).

Fig. 11.95 Plaque-like bladder tumor (histology: papillary

b Tumor-encased diverticula (D). The internal echoes are

urothelial carcinoma, probably a diverticular tumor).

caused by tumor tissue inside the diverticula. T = tumor.

a Tumor has spread over the bladder floor and (in other

 

planes) into both sidewalls, almost extending to the blad-

 

der roof on the left side. HB = bladder.

 

Circumscribed Wall Thickening

Urinary Tract

Malformations

Dilated Renal Pelvis and Ureter Renal Pelvic Mass, Ureteral Mass Changes in Bladder Size or Shape Intracavitary Mass

Wall Changes

Diffuse Wall Thickening Circumscribed Wall Thickening Concavities and Convexities

Bladder-Wall Hypertrophy

Bladder-Wall Edema

Bladder Carcinoma

Blood Clots

Bladder-WallHypertrophy

Bladder-wall hypertrophy is the most frequent

They most commonly occur on the bladder

cause of circumscribed bladder-wall thickening

floor and sidewalls, rarely affecting the bladder

demonstrated by ultrasound. The wall thick-

roof (Fig.11.96, Fig.11.97).

ness often exceeds 7 mm in cases due to infra-

Sites of inflammatory wall thickening due to

vesical obstruction. Pseudodiverticula gener-

infiltration from adjacent organs, as in Crohn

ally appear as anechoic, usually multiple, sharp

disease of the terminal ileum or peridiverticu-

or rounded protrusions of the bladder wall.

litis, are not uncommon.

The differential diagnosis should include clots or sludge adherent to the bladder wall, a flat circumscribed tumor, and especially a faulty examination technique with inadequate bladder filling.

Fig. 11.96 Wall hypertrophy in a trabeculated bladder with incipient pseudodiverticula. HB = bladder.

a B-mode image, lower abdominal transverse scan: relatively long, serrated area of circumscribed wall thickening (arrows) with adherent, fluid-filled bowel segment (D). Tumor was excluded by cystoscopy. Side-lobe artifacts are also visible.

b Color Doppler shows scattered vascular spots but no tumor vascularity. DA = bowel wall.

11

Wall Changes

411

11

Urinary Tract

Fig. 11.97 Circumscribed wall thickening on the bladder floor, raising suspicion of a tumor. HB = bladder.

a Lower abdominal transverse scan. Color Doppler shows no vessels. PR = prostate.

b Longitudinal scan shows a polypoid tumor mass (arrow). P = prostate. Cystoscopy showed a trabeculated bladder due to BPH.

Bladder-WallEdema

Circumscribed bladder-wall edema is usually based on mechanical irritation and inflammation from a bladder catheter, and so generally the cause is apparent.

Bladder Carcinoma

The most important sonographic diagnosis is a flat, circumscribed carcinoma of the bladder wall. It is occasionally difficult to distinguish from bladder-wall hypertrophy. Tumor spread through the bladder wall to neighboring organs, especially adjacent bowel segments (e. g., the sigmoid colon), and the presence of lymph node metastases prove that the lesion is a malignant process. Conversely, it is not uncommon to find bladder invasion by tumors in adjacent organs, such as ovarian or rectosigmoid cancer.

Flat, circumscribed bladder carcinoma most commonly occurs on the bladder floor in the

area of the trigone and ureteral orifices, leading to ureteral obstruction (Figs. 11.99, 11.100, 11.101).

Sonographic tumor staging is of limited accuracy in transabdominal ultrasound, but transurethral scanning is more reliable. The system for staging bladder tumors is shown in

Fig.11.98.

Bladder carcinoma is isoechoic to the rest of the bladder wall. Its outline is usually wavy but occasionally smooth. Sites of wall thickening near diverticula are always suspicious for carcinoma, as they are considered premalignant lesions (see Fig.11.105).

TNM In-

Tis

Ta

T1

T2

T3a

T3b

T4

volvement

 

 

 

 

 

 

 

of urothel-

 

 

 

 

 

 

 

ium, lamina

 

 

 

 

 

 

 

propria,

 

 

 

 

 

 

 

muscle lay-

 

 

 

 

 

 

 

ers, adventitia

 

 

 

 

 

 

 

Involve-

 

 

 

 

 

 

Prostate,

ment

 

 

 

 

 

 

uterus,

outside the

 

 

 

 

 

 

vagina,

bladder

 

 

 

 

 

 

abdomi-

 

 

 

 

 

 

 

nal wall,

 

 

 

 

 

 

 

pelvis

New TNM

 

0

I

II

 

III

IV

stage

 

 

 

 

 

 

 

 

 

(1992)

 

 

 

 

 

 

 

Fig. 11.98 Staging of bladder carcinoma.12

Fig. 11.99 Carcinoma involving the left side of the bladder floor. HB = bladder. R = rectum.

a Hypoechoic, slightly nonhomogeneous mass (T) spread over the bladder floor.

b Shifting the probe slightly shows involvement of the left ureteral orifice (arrow) causing ureteral obstruction

(U).

c Color Doppler: atypical spotty vascularity.

fFig. 11.100 Tumor spread over the bladder floor (arrows), with ureteral obstruction (U). HB = bladder.

Fig. 11.101 Recurrent urothelial carcinoma (arrow) in an 87-year-old woman 2 years after transurethral resection: flat, circumscribed, hypoechoic mass on the bladder floor.

412

Blood Clots

Blood clots or viscous sludge adherent to the bladder wall may be confused with real tumors (see above).

Concavities and Convexities

Urinary Tract

Malformations

Dilated Renal Pelvis and Ureter Renal Pelvic Mass, Ureteral Mass Changes in Bladder Size or Shape Intracavitary Mass

Wall Changes

Diffuse Wall Thickening Circumscribed Wall Thickening Concavities and Convexities

Ureteroceles

Diverticula

Ureteroceles

Protrusions from the bladder floor near the

Fig. 11.102 Ureterocele: elliptical, hyperechoic ureteral

wall herniating into the bladder from the area of the right

ureteral orifices are ureteroceles. Their ultra-

ureteral orifice. The wall layers can be identified.

sound appearance is described above

 

(Fig.11.102).

 

11

Wall Changes

Diverticula

Congenital bladder diverticula are based on a congenital weakness in the bladder wall, allowing a localized full-thickness herniation of the wall. They may be solitary or multiple and range in size from very small to extremely large. Diverticula predispose to stone formation and diverticular carcinoma (Fig.11.105),

which is why they should be surgically removed.

At ultrasound, diverticula typically appear as anechoic round or oval masses located outside the bladder wall. Most diverticula are connected to the bladder lumen by a neck or stalk. The wall of the diverticulum is thinner than the rest of the bladder wall. Diverticula may reach

a size exceeding that of the bladder, often causing them to be mistaken for cysts or the bladder itself. The diagnosis of diverticula is facilitated by examining the bladder in various degrees of distension (Figs. 11.103, 11.104, 11.105).

Pseudodiverticula are secondary reactions to subvesical obstructions, and so they are usually associated with wall hypertrophy,

Fig. 11.103 Large bladder diverticula: one located cranially (D) with a well-defined diverticular neck, and one located in the bladder floor, separated from the main lumen by an echogenic wall and containing a stone (arrow; acoustic shadow S). HB = bladder.

Fig. 11.104 Diverticulum (D) in the bladder floor, with a narrow neck (arrow). The sac contains a large stone (ST) with a wide acoustic shadow (S). HB = bladder.

Fig. 11.105 Extensive diverticular tumor (arrows): hypoechoic mass spread over the bladder floor and occupying the diverticula (D). HB = bladder.

413

11

Urinary Tract

producing a trabeculated bladder (Fig.11.106).

Fig. 11.106 Bladder-wall hypertrophy with numerous

They represent protrusions of the bladder mu-

pseudodiverticula, young man with BPH.

cosa between bundles of hypertrophied

 

muscle.

 

Tips, tricks, and pitfalls

Bladder polyps and tumors are among the most common accidental findings. Therefore, always pay attention to the bladder and minor pelvis (“sono-optic window”, which is more effective with a fully filled bladder).

Masses in the bladder present great difficulties in differentiating blood clots from solid tumors. Detectable vessels inside of a mass

may exclude sediments and clots. CEUS improves the differential diagnosis of intraluminal echoic masses, allowing the detection of tumors, which are vascularized and thus enhance, while clots do not enhance (Fig. 11.107).7

References

[1]Hohenfellner R, Walz RH. Primärer und sekundärer Megaureter. In: Hohenfellner R, Thüroff JW, Schulte-Wissermann H. Kinderurologie in Klinik und Praxis. Stuttgart: Thieme, 1986; p. 268

[2]Kröpfl D. Harnleiteranomalien. In: Jocham D, Miller H (eds.). Praxis der Urologie. Stuttgart: Thieme, 1995; p. 377

[3]Tuma J, Schwarzenbach HR. Die Sonographie bei Nierenkolik [Ultrasound for renal colic]. Praxis (Bern 1994) 2004;93:1767–1774

[4]Gladisch R. Praxis der abdominellen Ultraschalldiagnostik. 2nd ed. Stuttgart: Schattauer, 1992

An obstructed–dilated urinary tract is readily differentiable:

Always examine the region of the occlusion (Fig. 11.107). Small calculi are optimally diagnosable in the ureterovesical junction.

Ureteral calculi are detectable in a high percentage of cases (up to 98%3) by considering all of the clinical and sonographic diagnostic possibilities (color Doppler, twinkling artifact, compression, and observing the course of the ureter).

In case of urinary stasis the cause of obstruction should always be diagnosed: in acute stasis it is usually calculi, and in chronic stasis more often a tumor (ovary, prostate, colorectal.

[5]Jequier S, Paltiel H, Lafortune M. Ureterovesical jets in infants and children: duplex and color Doppler US studies. Radiology 1990;175(2):349–353

[6]Riedmiller H, Köhl U. Vesikoureteraler und vesikorenaler Reflux. In: Jocham D, Miller H (eds.). Praxis der Urologie. Stuttgart: Thieme, 1995; pp. 384–388

[7]Piscaglia F Nolsøe C, Dietrich CF, et al. The EFSUMB Guidelines and Recommendations on the Clinical Practice of Contrast Enhanced Ultrasound (CEUS): Update 2011 on non-hep- atic applications. Ultraschall Med 2012; 33(1):33–59

[8]Eble JN, Sauter G, Epstein JI, Sesterhenn IA (eds.). World Health Organization Classifica-

Fig 11.107 Ectated renal pelvis (P) caused by a cyst in the lower pole compressing the upper ureter (arrow).

tion of Tumours. Pathology and Genetics of Tumours of the Urinary System and Male Genital Organs. Lyon: IARC Press, 2004

[9]Gottfried HW. Ultraschall in der Urologie. In: Jocham D, Miller H (eds.). Praxis der Urologie. Stuttgart: Thieme, 1995; pp. 55–75

[10]Jocham D. Maligne Tumoren der Harnblase. In: Jocham D, Miller H (eds.). Praxis der Urologie. Stuttgart: Thieme, 1995; pp. 49–115

[11]Malone PR, Weston-Anderwood J, Aron PM. Transcutaneous ultrasound in the detection of superficial bladder cancer. Br J Urol 1985;58 (6):664–667

[12]Wilmanns W, Huhn D, Wilms K. Internistische Onkologie. Stuttgart: Thieme, 2000; p. 534

414

Prostate, Seminal

Testis, Epididymis

12

Vesicles,

The Prostate 417

 

 

 

Enlarged Prostate

418

 

 

 

 

 

 

 

 

 

Regular

418

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Benign Prostatic Hyperplasia

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Prostatic Carcinoma

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Acute Prostatitis

 

 

 

 

 

 

 

Irregular

421

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Benign Prostatic Hyperplasia

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Prostatic Carcinoma

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Chronic Prostatitis

 

 

 

 

Small Prostate

422

 

 

 

 

 

 

 

 

Regular

422

 

 

 

 

 

 

 

 

 

 

 

 

 

Operated Prostate

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Radiation Therapy

 

 

 

 

 

 

 

Echogenic

423

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Chronic Prostatitis

 

 

 

Circumscribed Lesion

423

 

 

 

 

 

 

 

Anechoic

423

 

 

 

 

 

 

 

 

 

 

 

 

 

Abscess, Cavity

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Utricular Cyst,

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Ectopic Ureter

 

 

 

 

 

 

 

 

 

After Transurethral Resection

 

 

 

 

 

 

Hypoechoic

424

 

 

 

 

 

 

 

 

 

 

 

 

 

Benign Prostatic Hyperplasia

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Prostatic Carcinoma

 

 

 

 

 

 

 

Echogenic

426

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Stones, Calcifications

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

“Surgical Capsule”

 

Seminal Vesicles

426

 

 

 

Diffuse Change

426

 

 

 

 

 

 

 

 

Hypoechoic

426

 

 

 

 

 

 

 

 

 

 

 

 

Vesiculitis

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Tumor Infiltration

 

 

Circumscribed Change

427

 

 

 

 

 

Anechoic

427

 

 

 

 

 

 

 

 

 

 

 

Dilatation, Cyst

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Abscess

 

 

 

 

 

Echogenic

428

 

 

 

 

 

 

 

 

 

 

 

Stones, Calcifications

 

 

 

 

 

Irregular

428

 

 

 

 

 

 

 

Chronic Vesiculitis

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Tumor Infiltration

 

Testis, Epididymis 429

 

Diffuse Change

430

 

 

Enlargement

430

 

 

 

 

 

 

 

 

 

Orchitis

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Testicular Torsion

 

 

 

 

Decreased Size

431

 

 

 

 

 

 

 

 

 

 

Anorchism, Cryptorchidism

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Hypogonadism

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Atrophy

 

Circumscribed Lesion

431

 

 

Anechoic or Hypoechoic

431

 

 

 

 

 

 

 

 

 

Testicular Cyst

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Hematoma

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Abscess

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Testicular Infarction

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Testicular Tumor

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Irregular/Echogenic

433

 

 

 

 

 

 

 

 

 

 

 

Testicular Microlithiasis

 

Epididymal Lesion

434

 

 

 

 

Anechoic

434

 

 

 

 

 

 

 

 

 

 

 

Spermatocele, Epididymal Cyst

 

 

 

 

 

 

Hypoechoic

434

 

 

 

 

 

 

 

 

 

 

 

 

Epididymitis

 

 

 

Intrascrotal Mass

435

 

 

 

 

 

Anechoic or Hypoechoic

435

 

 

 

 

 

 

 

Hydrocele

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Varicocele

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Hematocele

 

 

 

 

 

 

Echogenic

436

 

 

 

 

 

 

 

 

 

 

 

 

Fibroma of the Tunica/

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Corpus Librum

 

Scrotal Hernia

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