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II.13. Переведите письменно абзацы 8 и 9 текста с.

III. Послетекстовые упражнения

III.1. Изучите следующую таблицу и заполните пропуски названиями основных инертных ингредиентов таблетки.

Table 1. Common tablet excipients

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

. . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Calcium phosphate dihydrate

Cellulose

Calcium sulfate dihydrate

Alginates

Dextrose

Cellulose derivatives

Lactose

Clays

Mannitol

Starch

Sorbitol

Starch derivatives

Starches

Sucrode-based materials

Stearic acid

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Stearic acid salts

Acacia

Surfactants

Cellulose derivatives

Talc

Gelatin

Waxes

Glucose

PEGs

Tragacanth

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

PVP

Cornstarch

Sodium alginate

Silica derivatives

Starch (paste

Talc

Starch (pregelatinized

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Sorbitol

FD&C and D&C dyes

Flavours in two forms:

spray-dried and oils

Artificial sweeteners

Natural sweeteners

D&C = drug and cosmetics; FD&C = food, drug and cosmetics;

PEG = polyethylene glycol; PVP = polyvinylpyrrollidone, more commonly called povidone

III.2. Выберите правильные варианты ответов.

  1. The dispensing pharmacist usually blends potent powders with a large amount of diluent by

(A) spatulation

(B) sifting

(C) trituration

(D) geometric dilution

  1. Which type of paper best protects a divided hygroscopic powder?

(A) waxed paper

(В) glassine

(C) white bond

(D) vegetable parchment

  1. Which capsule size has the smallest capacity?

(A) 5

(B) 1

(C) 0

(D) 000

  1. Divided powders may be dispensed in

(A) individual-dose packets

(B) a bulk container

(C) a perforated, sifter-type container

III.3. Начертите схему, представляющую разнообразие твёрдых дозированных форм и расскажите о преимуществах и недостатках каждой из них.

III.4. Прочтите и переведите письменно этот отрывок текста.

То satisfy the USP standards, tablets are required to pass one of two tests. A weight variation test is used if the active ingredient comprises the bulk of the tablet. A content uniformity test is used if the tablet is coated or if the active ingredient comprises less than 50% of the bulk of the tablet. Many tablets for oral administration are required to pass a disintegration test. Disintegration times are specified in the individual monographs. A dissolution test may be required instead if the active component of the tablet has limited water solubility. Hardness and friability would affect the disintegration and dissolution rates, but hardness and friability tests are in-house quality control tests, not official USP tests.