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- •Contents
- •List of contributors
- •Preface
- •Introduction
- •Materials and methods
- •Plants traditionally used in Colombia as antimicrobials
- •Xanthium strumarium L. (Asteraceae)
- •Guazuma ulmifolia Lam. (Malvaceae)
- •Cymbopogon citratus (DC.) Stapf (Poaceae)
- •Austroeupatorium inulaefolium (Kunth) R.M.King & H.Rob. (Asteraceae)
- •Jacaranda caucana Pittier (Bignoniaceae)
- •Solanum nudum Dunal (Solanaceae)
- •Hymenaea courbaril L. (Leguminosae)
- •Biological evaluation as antimicrobials of plant extracts in Colombia
- •Antibacterial activity
- •Otholobium mexicanum (L.f.) J.W. Grimes. (Fabaceae)
- •Cucurbita moschata Duchesne (Cucurbitaceae)
- •Cymbopogon citratus (DC.) Stapf (Poaceae)
- •Conobea scoparioides (Cham. & Schltdl.) Benth (Scrophulariaceae)
- •Rosmarinus officinalis Govaerts. (Lamiaceae)
- •Antiparasitic activity
- •Miconia theaezans (Bonpl.) Cogn. (Melastomataceae)
- •Annona purpurea Dunal (Annonaceae)
- •Guatteria amplifolia Triana & Planch. (Annonaceae)
- •Annona muricata Linn. (Annonaceae)
- •Austroeupatorium inulifolium (Kunth) R.M. King & H. Rob. (Compositae)
- •Campnosperma panamense Standl. (Anacardiaceae)
- •Huberodendron patinoi Cuatrec. (Bombacaceae)
- •Swinglea glutinosa Merr (Rutaceae)
- •Antiviral activity
- •Annona sp. (Annonaceae)
- •Byrsonima verbascifolia L. DC (Malpighiaceae)
- •Vismia macrophylla Kunth. (Clusiaceae)
- •Mammea americana L. (Calophyllaceae)
- •Maclura tinctoria L. D.Don ex Steud. (Moraceae)
- •Conclusions
- •References
- •Lebanese plants with antimicrobial activity
- •Amaryllidaceae
- •Allium cepa/Allium sativum
- •Anacardiaceae
- •Pistacia species
- •Apiaceae
- •Prangos asperula
- •Asteraceae/Compositae
- •Matricaria species
- •Berberidaceae
- •Berberis libanotica
- •Cannabaceae
- •Humulus lupulus
- •Cistaceae
- •Cistus species
- •Conifers
- •Lamiaceae
- •Phlomis species
- •Cyclotrichium species
- •Salvia species
- •Rosmarinus officinalis
- •Thymol/carvacrol rich species
- •Za’atar plants: Satureja thymbra; Origanum syriacum
- •Different Lamiaceae genera
- •Thymbra spicata
- •Myrtaceae
- •Eucalyptus species
- •Portulacaceae
- •Portulaca oleracea
- •Ranunculaceae
- •Clematis vitalba
- •Nigella sativa
- •Rutaceae
- •Ruta species
- •Rosaceae
- •Rosa damascena
- •Conclusion
- •References
- •Introduction
- •Medicinal plants with antimicrobial properties
- •Amaryllidaceae
- •Allium sativum L.
- •Picea abies (L.) H.Karst.
- •Rosaceae
- •Agrimonia eupatoria L.
- •Prunus spinosa L.
- •Rosa canina L.
- •Rubus fruticosus L.
- •Urticaceae
- •Urtica dioica L.
- •Conclusions
- •References
- •Apiaceae
- •Petroselinum crispum (Mill.) Fuss
- •Asteraceae
- •Achillea millefolium L.
- •Artemisia absinthium L.
- •Calendula officinalis L.
- •Matricaria chamomilla L.
- •Betulaceae
- •Alnus glutinosa (L.) Gaertn.
- •Lamiaceae
- •Lavandula angustifolia Mill.
- •Mentha longifolia (L.) L.
- •Mentha x piperita L.
- •Ocimum basilicum L.
- •Origanum vulgare L.
- •Malvaceae
- •Althaea officinalis L.
- •Malva sylvestris L.
- •Pinaceae
- •Larix decidua Mill.
- •Introduction
- •Pathophysiology of wound healing
- •Wound infection
- •Currently available treatments and products
- •Topical creams
- •Transdermal drug delivery systems
- •Bacteria associated with infections of dermal wounds
- •Bacillus subtilis
- •Staphylococcus aureus
- •Staphylococcus epidermidis
- •Pseudomonas aeruginosa
- •Aloe barberae Dyer
- •Traditional usage
- •Aloe excelsa Berger
- •Traditional usage
- •Aloe ferox Miller
- •Traditional usage
- •Elephantorrhiza elephantina (Burch.) Skeel
- •Traditional usage
- •Erythrina lysistemon Hutch
- •Traditional usage
- •Galenia africana L
- •Traditional usage
- •Grewia occidentalis L
- •Traditional usage
- •Melianthus comosus Vahl.
- •Traditional usage
- •Traditional usage
- •Polystichum pungens (Kaulf.) C. Presl
- •Traditional usage
- •Sutherlandia frutescens (L.) R.Br.
- •Traditional usage
- •Urtica urens L.
- •Traditional usage
- •Aloe species
- •Elephantorrhiza elephantina
- •Erythrina lysistemon
- •Galenia africana
- •Melianthus comosus
- •Plectranthus fruticosus
- •Sutherlandia frutescens
- •Discussion
- •Conclusion
- •Index
- •Glossary
- •References
- •Introduction
- •Background on gonorrhea
- •The causal agent: Neisseria gonorrhoeae
- •Pathogenesis of Neisseria gonorrhoeae and evasion of host immune system
- •Evasion of host immune system via nutrition immunity
- •Coinfections of Neisseria gonorrhoeae
- •Status of available treatments for gonorrhea
- •Aloe ferox
- •Cassia abbreviata
- •Combretum molle
- •Elaeodendron transvaalense
- •Hypoxis hemerocallidea
- •Peltophorum africanum
- •Tabernaemontana elegans
- •Terminalia sericea
- •Conclusion
- •References
- •Introduction
- •Antibacterial properties of different medicinal plants from Pakistan
- •Conclusion
- •References
- •Introduction
- •Traditional medicine for diarrheal diseases in the Mekong Basin
- •The role of traditional medicine in the management of diarrhea
- •The cultural belief system of people living in the Mekong area
- •Pharmacological validation of plants used for diarrhea
- •Models assessing the effect of plants on the signs and symptoms of diarrhea
- •Antidiarrheal effect
- •Spasmolytic activity
- •Models assessing the antimotility and antisecretory activities
- •Antimotility activity
- •Antisecretory activity
- •Models assessing the antiinfective properties
- •Antibacterial activity
- •Antiviral and antiparasitic activity
- •Other models
- •Medicinal plants used for diarrhea in the lower Mekong basin
- •Literature search methodology
- •Overview of the dataset
- •Discussion of some selected plant species
- •Psidium guajava
- •Chromolaena odorata
- •Alstonia scholaris
- •Allium sativum
- •Centella asiatica
- •Punica granatum
- •Caesalpinia sappan
- •Mangifera indica
- •Holarrhena pubescens
- •Oroxylum indicum
- •Conclusion
- •References
- •Introduction
- •Traditional use of medicinal plants in West Africa
- •In vitro antimalarial evaluation of plant extracts
- •In vivo antimalarial evaluation of plant extracts
- •In vitro and in vivo evaluation of antimalarial compounds
- •The case of Artemisia in West Africa
- •Conclusion
- •References
- •Introduction
- •Significance of quorum quenching research
- •Current state of quorum quenching research
- •Quorum sensing versus quorum quenching
- •Biofilms
- •Background on biofilms
- •Biofilms and Mycobacterium tuberculosis
- •Virulence factors
- •Background on virulence factors
- •Virulence factors and Mycobacterium tuberculosis
- •Medicinal plants as quorum quenching agents
- •Medicinal plants and mycobacterial quorum quenching
- •Phytochemicals used in bacterial quorum quenching
- •Conclusion
- •References
- •Introduction
- •Plants as sources of antiinfective agents
- •Bioassay-guided fractionation
- •Metabolomics
- •Methods of detection
- •Data analysis
- •Biochemometrics
- •Metabolomics-driven antiinfective discovery from plants
- •Challenges and future directions
- •Metabolome coverage
- •Annotation/identification
- •Synergy
- •Conclusions
- •References
- •Introduction
- •Taxonomy and DNA barcoding
- •Infectious diseases and antiinfective plants
- •Herbal products, commercialization, and quality issues of antiinfective plants
- •Advancements in quality control methods
- •Materials and methods
- •Results and discussion
- •Embelia ribes—anthelmintic plant
- •Swertia chirayita—antiviral plant
- •Picrorhiza kurroa—antiviral plant
- •Paris polyphylla—anthelmintic plant
- •Saussurea costus—anthelminthic/antiparasitic plant
- •Syzygium aromaticum—antimicrobial plant
- •Andrographis paniculata—antimicrobial plant
- •Future perspectives
- •References
- •Introduction
- •Current situation of microbial infections
- •Microbial natural products as sources of new drugs
- •Endophytic fungi
- •Antimicrobial compounds from endophytic fungi
- •Antibacterial compounds
- •Alkaloids
- •Pyrazin-2-one
- •Piperine
- •Pyrrocidines
- •Bisindoles
- •Peptides
- •Dipeptides
- •Polypeptides
- •Polyketides
- •Chromones
- •Quinones
- •Xanthones
- •Benzofurans
- •Octaketides
- •Benzophenones
- •Terpenoids
- •Antivirulence compounds
- •Antiparasitic compounds
- •Antileishmanial compounds
- •Polyketides
- •Polyketide-alkaloids
- •Terpenoids
- •Antiplasmodial
- •Alkaloids
- •Polyketides
- •Polyketide-alkaloid
- •Polypeptides
- •Terpenoids
- •Antitrypanosomal/antiplasmodial/antileishmanial compounds
- •Polyketides
- •Polypeptides
- •Discussion and conclusion
- •References
- •Introduction
- •Dengue disease
- •Conventional treatment
- •Medicinal plants
- •Introduction
- •Psidium guajava: a potential antidengue medicinal plant
- •A metabolomic approach in antiviral compound identification
- •Objectives
- •Results
- •UHPLC-HRMS-based metabolomics approach
- •Antidengue activity
- •Identification of putative antidengue compounds
- •Antidengue assay of pure authentic standards
- •Discussion
- •Materials and methods
- •Plant collection
- •Leaf extraction
- •Cells and virus
- •Extracts preparation
- •Cell viability assay
- •Virus infection
- •UHPLC-HRMS profiling
- •Data processing
- •Statistical analysis
- •Identification of significant features
- •References
- •Introduction
- •Brief history of Arabic medicine
- •Principles of Arab medicine: theoretical aspects
- •Cutaneous infections and medications
- •Plants and metals useful for skin diseases
- •Toxicity of metals
- •Elementary metal particle
- •Organometallic molecule
- •Metal nanoparticles
- •Conclusion
- •References
- •Introduction
- •General information on improved traditional medicines
- •Definition
- •Regulatory framework
- •Categories of improved traditional medicines
- •Marketing authorization files for ITMs in Mali

on the medicinal use of plants has been recorded directly on the basis of a detailed survey
on herbalists, folk healers, older experienced people, and midwives. All those that might
have been obtained information from secondary sources were excluded. Only remedies
that were said to be handed down by oral tradition were considered. Furthermore, only
species that could be directly indicated and collected by the persons interviewed are cited.
All the wild plants used have local vernacular names that point to their rather ancient use.
The herbalists were interviewed using a questionnaire similar to the form for botanical
and ethnopharmacognosic investigation of plants used in traditional medicine produced
by WHO (
Penso, 1980). Medicinal plants have been identified based on the “Nouvelle flore
du Liban et de la Syrie” Mouterde (1966, 1970, and 1983). We note that the new phyloge-
netic classification APG II 2003 (Angiosperm Phylogeny Group, 2003) was adopted in
order to update the families cited in Mouterde.
Acknowledgment
The authors are grateful to The TWAS Young Affiliates Network (TYAN) that supported the cooperation with the
book editor through the TYAN Collaborative Grant Award F.R. 3240307334 that allowed the first author’s travel
to Emory University, USA.
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