Добавил:
Sekretar
kiopkiopkiop18@yandex.ru
t.me/Prokururor I Вовсе не секретарь, но почту проверяю
Опубликованный материал нарушает ваши авторские права? Сообщите нам.
Вуз:
Предмет:
Файл:Ординатура / Хирургия / Библиотека им академика М.И. Перельмана / Книга_5264_Библиотеки_им_академика_М_И_Перельмана.pdf
Plant- based Foods and their
Implications in Brain Health
Phytoconstituents are a valuable source of new lead compounds due to their structural variety.
The accelerated rate of human ageing brought about by the 21st century’s longer life expectancy
seems to be one of the major problems facing varied cultures worldwide. Ageing and the onset of
people follow throughout their lives. There is strong evidence that Mediterranean diets are linked
to a lower risk of brain disorders. A greater proportion of rural communities in the Mediterranean
basin eat a diet high in plant- based foods daily. Stressors like reactive oxygen and reactive nitrogen
Foods, particularly those derived from plants, are a great source of vitamins, antioxidants,
polyphenols, and vital fatty acids, according to a growing body of epidemiological research. Studies
by reducing the amount of oxidative stress and controlling different signal transduction pathways,
according to a large body of experimental evidence.
to various types of plant- based phytoconstituents. The book’s content is relevant and interesting to
a wide range of audiences from the backgrounds of plant sciences, pharmacy, biochemistry, and
molecular biology. Apart from being a good reference material source, the book is relevant to plant
Plant- based Foods and their
Implications in Brain Health
Edited by
Soumya Mukherjee, Akula Ramakrishna, and
Atanu Bhattacharjee
Designed cover image: Shutterstock
First edition published 2025
by CRC Press
2385 NW Executive Center Drive, Suite 320, Boca Raton FL 33431
and by CRC Press
4 Park Square, Milton Park, Abingdon, Oxon, OX14 4RN
CRC Press is an imprint of Taylor & Francis Group, LLC
© 2025 selection and editorial matter, Soumya Mukherjee, Akula Ramakrishna, and Atanu Bhattacharjee; individual
chapters, the contributors
Reasonable efforts have been made to publish reliable data and information, but the author and publisher cannot assume
responsibility for the validity of all materials or the consequences of their use. The authors and publishers have attempted
to trace the copyright holders of all material reproduced in this publication and apologize to copyright holders if permission
to publish in this form has not been obtained. If any copyright material has not been acknowledged please write and let us
know so we may rectify in any future reprint.
Except as permitted under U.S. Copyright Law, no part of this book may be reprinted, reproduced, transmitted, or utilized
in any form by any electronic, mechanical, or other means, now known or hereafter invented, including photocopying,
For permission to photocopy or use material electronically from this work, access www.copyri ght.com or contact the
Copyright Clearance Center, Inc. (CCC), 222 Rosewood Drive, Danvers, MA 01923, 978- 750- 8400. For works that are not
available on CCC please contact mpkbookspermissions@tandf.co.uk
Trademark notice
and explanation without intent to infringe.
ISBN: 978- 1- 032- 29231- 1 (hbk)
ISBN: 978- 1- 032- 29232- 8 (pbk)
ISBN: 978- 1- 003- 30050- 2 (ebk)
DOI: 10.1201/ 9781003300502
Typeset in Times New Roman
by Newgen Publishing UK
v
Contents
Foreword ..........................................................................................................................................vii
Preface ...............................................................................................................................................ix
Editors’ bio ........................................................................................................................................ xi
Contributors ....................................................................................................................................xiii
Chapter 1 Neurobiology: An Overview ........................................................................................ 1
Rashid Hussain, Shabana Bibi, Ammara Saleem, Arghya Bhattacharya,
Jaweria Syed, Nobendu Mukerjee, and Athanasios Alexiou
Chapter 2 Plants as Neuroprotective Agents: Role of Plant- Based Natural Products
as Potential Brain Health Boosters ............................................................................. 13
Vanshika Sharma, Yutika Nath, and Ranjan Dutta Kalita
Chapter 3 Āyurvedic Psychotropic Drugs (Medhya Rasayan Drugs) and Their
Effect on Manovaha Srotas ........................................................................................22
Jasmeet Singh, Nanki Singh, Sneh Shalini, Sunil Kumar Rai, Garima Malik,
Rinki Kumari, and G.P. Dubey
Chapter 4 Potential Impact of Indian Herbs and Spices in Prevention of
Pathogenesis of Alzheimer’s Disease ......................................................................... 44
Paramita Bhattacharjee, Anamika Das, and Sanjukta Datta
Chapter 5 ................................................................................... 95
Olakunle J. Onaolapo and Adejoke Y. Onaolapo
Chapter 6 Neuroprotective Potential of Some Traditional Indian Medicinal Plants in
Alzheimer’s and Parkinson’s Disease ......................................................................112
Bharti Chaudhry
Chapter 7 Role of Herbal Drugs as Potential Therapeutics in Dementia .................................. 126
Soumya Mitra, Subhash C. Mandal, and Nilanjan Ghosh
Chapter 8 Marine Plant Species: Nutritional and Medicinal Value for Brain Health ...............149
Shaileyee Das
Chapter 9 Walnut (Juglans regia L.) as Brain Food .................................................................198
Atanu Bhattacharjee, Akula Ramakrishna, and Kunal Bhattacharya
vi
Contents
Chapter 10 A Molecular Insight into Plant Bioactive Congeners as Neuroprotective
Therapeutics .............................................................................................................209
Swarupananda Mukherjee, Dipanjan Karati, Mainak Chakraborty,
Nilanjan Sarkar, Souvik Roy, and Sajal Kumar Jha
Chapter 11 Plant Phenols and Their Potential Modulation of Neurochemistry .......................... 226
Rahul Kumar Sharma, Shilpa Thakur, Navidha Aggarwal, and
Hitesh Chopra
Chapter 12 Plant Phytochemicals as Potential Therapeutics in Neurological Disorders ............ 239
Pawan Prabhakar, Ankit Kumar, and Mamoni Banerjee
Chapter 13 Phytoconstituents: The Natural Tonic for a Healthy Brain ...................................... 262
Bapi Ray Sarkar, Simran Giri, Ganesh Dey, and Prosanta Pal
Chapter 14 Effect of Edible Alkaloids on Memory and Behaviour ............................................ 275
Kunal Bhattacharya, Dibyajyoti Das, Debabrata Nath,
Nongmaithem Randhoni Chanu, and Ramen Kalita
Chapter 15 Caffeine and Motor Skills ........................................................................................291
Robert Lalonde and Catherine Strazielle
Chapter 16 Melatonin and the Brain ........................................................................................... 317
Shabana Bibi, Sana Javed, Farah Alam Gill, Shopnil Akash,
Hitesh Chopra, Ammara Saleem, and Rashid Hussain
Chapter 17 Narcotics and Brain Health ......................................................................................328
Rashid Hussain, Shabana Bibi, Muhammad Asad Ali, Shopnil Akash,
Nobendu Mukerjee, Ammara Saleem, and Athanasios Alexiou
Chapter 18 Nutraceuticals in Brain Health ................................................................................. 342
Pratap Kalita, Bedanta Bhattacharjee, Ram Kumar Sahu, and
Satyabrat Sarma
Chapter 19 Impact of Prenatal Diet on the Developing Brain of the Fetus ................................ 360
Kunal Bhattacharya, Biswajit Devanath, Surender Prasad,
Tasrina Rahman, and Nongmaithem Randhoni Chanu
vii
Foreword
I am delighted to introduce and endorse the forthcoming publication of
the book titled “Plant-based Foods and their Implications in Brain
Health.” This comprehensive reference book is a monumental step for-
ward in neuroscience, as it assembles the latest information on edible
medicinal plants and their potential role in managing the healthy status
of our brains. Authored by distinguished experts, this book is invaluable
for professionals, researchers, and students in neuroscience, traditional
medicine, psychology, and pharmacognosy.
The book is not only about basic information about the brain but also
explores various in- vitro and in- vivo strategies to encounter progres-
sive neuro- degenerative disorders like Alzheimer’s disease. It provides
in- depth knowledge about the use of marine resources, phytocompounds and their possible role in
maintaining the positivity of the brain to keep it disorder and disease- free. Furthermore, it discusses
the crucial role of phytomolecules and natural products in Alzheimer’s therapy, an area that holds
great promise for future treatments. One of the key strengths of this reference book is its coverage of
biomarker analysis for Alzheimer’s disease. Identifying reliable biomarkers is pivotal in early diag-
nosis and monitoring, and the insights offered in this book can potentially impact clinical practice
and research efforts. This insight is essential for developing targeted interventions and improving
our understanding of the disease process in the case of treatment of Alzheimer’s patients.
date resource for those who are deeply committed to addressing the challenges of brain health
Prof. (Dr.) S. P. Singh
Vice- Chancellor
The Assam Royal Global University
Guwahati- 781035, Assam, India
ix
Preface
Life expectancy in the 21st century has led to increased rates of human ageing, which appears to be
one of the biggest challenges in diverse communities worldwide. The nature of food consumption
patterns throughout the human life cycle seems to have a major impact on ageing and the devel-
opment of chronic diseases. Convincing evidence exists in terms of reduced risk of brain disorder
to be associated with Mediterranean diets. In the Mediterranean basin, a wider percentage of rural
populations consume a daily diet rich in foods of plant origin. Apart from the cardiovascular system,
nitrogen species. The structural diversity of phytoconstituents makes them a valuable source of novel
lead compounds for the quest for drugs to improve brain health. In the human brain, the ageing pro-
grey and white matter volume concomitant with other bio- molecular changes. Increasing evidence
from epidemiological studies has revealed that foods, especially those of plant origin, are rich in
essential fatty acids, polyphenols, vitamins, and antioxidants. Investigations suggest an impact of
-
mental evidence reveals that polyphenols and other plant- derived bioactivities modulate animal and
human brain function by lowering oxidative stress load and by regulating various signal transduc-
tion pathways. Omega- 3 polyunsaturated fatty acids (n- 3 PUFAs) in Mediterranean diets may exert
some neuropsychiatric disorders, particularly depression, as well as in brain ageing, dementia, and
Alzheimer’s disease. PUFAs cannot be synthesized de novo but can be formed from linoleic acid
-
(serotonin, melatonin, GABA, and dopamine) that are widely distributed in the leaves, seeds, bark,
alcoholic beverages and narcotics also exhibit a concentration dependence on brain health and the
volume compiles recent advancements in investigations pertaining to plant- derived food and brain
health.