Burns are serious pathological conditions that occur as a result of traumatic effects of thermal, chemical, electrical activity or radiation to the skin tissue, triggering inflamma­tory responses and increasing the risk of infection. Millions of people worldwide experi­ence burn injuries every year, and this situation poses a serious public health problem, especially in low- and middle-income countries due to limited healthcare services. The main goals in burn treatment are to accelerate wound healing, prevent infection, con­trol inflammation and manage pain. However, the limitations of modern treatment methods related to cost, accessibility, and side effects have increased interest in herbal treatments. Medicinal and aromatic plants exhibit anti-inflammatory, antibacterial, an­algesic, and wound-healing properties through bioactive compounds such as flavonoids, phenolic acids, alkaloids, tannins, essential oils, and saponins. These properties provide multifaceted effects that support the healing of both acute and chronic burn wounds. Plants such as Aloe vera, Calendula officinalis, Hypericum perforatum, Mentha piperita, and Syzygium aromaticum, which have been used in traditional medicine for centuries are prominent examples in this field. The effects of these plants, such as reducing burn­related inflammation, preventing infection and accelerating the regeneration of wound tissue, have also been supported by modern scientific research. For example, Aloe vera gel offers moisturizing, anti-inflammatory, and cell-regenerating effects thanks to its ac­tive ingredients such as polyphenols and anthraquinone derivatives, while Hypericum perforatum has antimicrobial and antioxidant effects with its hypericin content. Histori­cally, plants used in the treatment of burns represent one of the oldest medical practi­ces of humanity. The therapeutic effects of these plants have been passed down from generation to generation in different cultural traditions such as traditional Chinese medicine, Ayurveda, Middle Eastern folk medicine, and Anatolian medicine and have survived to the present day. Modern medicine integrates this traditional knowledge into pharmaceutical practices, supported by biochemical analyses and clinical studies. For example, Hypericum perforatum extract has found its place in modern pharmacy in the form of commercial ointments and creams. Similarly, clinical studies on the wound­healing effects of Calendula officinalis have popularized the use of this plant in medical preparations.

Burn areas are highly vulnerable to the risk of infection. Herbal components with an­timicrobial properties play a critical role in preventing wound infections [4].