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Advances in Pharmaceutical Technology for Drug Delivery Systems (PTDDS), Volume 2
Regenerative Medicine
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Advances in Pharmaceutical T echnology for Drug Delivery Systems (PTDDS), Volume 2: Recent Progress
in Biomedical Applications. Sougata Jana (Ed.)
© 2025 Apple Academic Press, Inc. Co-published with CRC Press (Taylor & Francis)
Bioceramics System for Biomedical
Application
V. LALZAWMLIANA
1
, PRASENJIT MUKHERJEE
2
, SUBHASIS ROY
2
,
SHUBHAMITRA CHAUDHURI
2
, and SAMIT KUMAR NANDI
3
1
2
3
CHAPTER 10
ABSTRACT
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approaches such as orthopedic surgery, drug delivery systems, dental
discuss recent advancements in bioceramics systems and their application
in biomedical sciences.
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Advances in Pharmaceutical Technology for Drug Delivery Systems (PTDDS), Volume 2
10.1 INTRODUCTION
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(titanium or tantalum), polymers (polylactides), hydrogel-based mate-
rials, bioceramics, biocomposite structures, etc. (Bohner et al., 2012).
various biomedical applications such as hip and knee replacement, and
(Saini et al., 2015).
Bioceramics System for Biomedical Application
293
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materials are mostly bioactive and bioresorbable ceramics, such as calcium
should degrade at the same rate as the tissue regeneration and excrete
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Advances in Pharmaceutical Technology for Drug Delivery Systems (PTDDS), Volume 2
10.2 IDEAL PROPERTIES OF BIOCERAMICS
usually 3D structures to provide mechanical support and also promote the
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causing any adverse reaction to the body . In addition to its acceptance by the
10.2.1 MECHANICAL PROPERTY
-
optimum in vivo
completely regenerated (Hollinger and Chaudhari, 1992). Additionally, the
ceramic material must possess other properties such as optimum elasticity,
-
Bioceramics System for Biomedical Application
295
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2015).
10.2.2 POROSITY, PORE SIZE, AND SHAPE
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bone healing. A larger interconnected pore structure can be attained by rapid
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(Leong et al., 2003).
10.2.3 BIOCOMPATIBILITY AND BIODEGRADABILITY
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be nontoxic, nonteratogenic, noncarcinogenic, nonallergic, nonhemolytic,
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Bioceramics System for Biomedical Application
297
bioresorbable properties (Bohner, 2000).
10.2.4 OSTEOCONDUCTIVITY AND OSSEOINTEGRITY
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and biodegradability (Li et al., 2021). Besides, osteointegration means the
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