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Файл:Ординатура / Хирургия / Библиотека им академика М.И. Перельмана / Книга_5463_Библиотеки_им_академика_М_И_Перельмана.pdf
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- •About the Editor
- •Contents
- •Contributors
- •1.1.4 Components of niosome
- •1.1.5 Factors affecting niosomes
- •Preface
- •Abstract
- •1.1 Introduction
- •1.1.1 Why niosome?
- •1.1.2 Advantages of niosome
- •1.1.3 Structure of niosome
- •1.2 Applications of niosome
- •1.2.2 Niosomes for the delivery of therapeutics
- •1.2.3 Niosomes in biomedical applications
- •1.3 Conclusions and future prospects
- •Keywords
- •References
- •Abstract
- •2.1 Introduction
- •2.2 Conclusions
- •Acknowledgments
- •Keywords
- •References
- •Abstract
- •3.1 Introduction
- •3.2.1 Parameters involved in electrospinning process
- •3.2.2 Biomaterials for electrospinning
- •3.3 Electrospun nanofibers as drug delivery systems
- •3.3.1 Blending electrospinning
- •3.3.2 Emulsion electrospinning
- •3.3.3 Coaxial electrospinning
- •3.3.4 Surface modifications
- •3.4 Electrospun nanofibers for tissue engineering
- •3.4.1 Electrospun nanofibers for hard tissue engineering
- •3.5 Cancer diagnosis and therapy
- •3.6 Concluding remarks and future perspectives
- •Keywords
- •References
- •4. Natural Biocarriers for Brain Targeting
- •Abstract
- •4.1 Introduction
- •4.1.1 Central nervous system
- •4.2 Biocarriers
- •4.2.1 Carbohydrates carriers
- •4.2.2 Protein carriers
- •4.2.3 Exosomes
- •4.3 Conclusions and perspectives
- •Keywords
- •References
- •Abstract
- •5.1 Introduction
- •5.2 Synthesis of graphene family nanomaterials
- •5.2.1 Graphene synthesis
- •5.2.2 GO and rGO Syntheses
- •5.2.3 GQd synthesis
- •5.4 Drug delivery and biomedical applications
- •5.4.1 Drug delivery
- •5.4.2 Gene delivery
- •5.4.3 Bioimaging
- •5.4.4 Photothermal therapy
- •5.4.5 Tissue engineering
- •5.5 Summary and future prospect
- •Keywords
- •References
- •6. Nanotechnology in Gene Delivery
- •Abstract
- •6.1 Introduction
- •6.2 Gene delivery
- •6.3 Nanotechnology in gene delivery
- •Keywords
- •References
- •Abstract
- •7.1 Introduction
- •7.2 Additive manufacturing in pharmacology
- •7.2.1 Extrusion-based 3D printing techniques
- •7.2.2 Stereolithography
- •7.2.3 Selective laser sintering
- •7.2.4 Binder jet printing
- •7.3 Most common polymers
- •7.3.1 Natural polymers
- •7.3.2 Synthetic polymers
- •7.3.2.5 Polyvinylpyrrolidone
- •7.4 Common 3D-printed dosage forms
- •7.4.1 Scaffolds
- •7.4.2 Tablets
- •Keywords
- •References
- •7.4.3 Microneedles
- •7.4.4 Capsule
- •7.4.5 Films
- •7.5 Main factors in drug delivery
- •7.5.1 Nature of polymers
- •7.5.2 Matrix permeability
- •7.5.3 Polymer blends
- •7.5.4 Specific surface area
- •7.5.5 Infill density and patterns
- •7.5.6 Pores
- •7.5.7 Cross-linking
- •7.5.8 Coating
- •7.5.9 Core/shell and multicompartment
- •7.6 Final considerations and future perspectives
- •Abstract
- •8.1 Introduction
- •8.2.1 Polymer solution concentration and viscosity
- •8.2.2 Molecular weight of polymer
- •8.2.3 Surface tension
- •8.2.4 Electrical conductivity
- •8.2.5 Applied voltage
- •8.2.6 Feed rate/flow rate
- •8.2.7 Temperature and humidity
- •8.3 Method of preparation for nanofibers
- •8.3.1 Electrospinning
- •8.3.2 Self-assembly
- •8.3.3 Phase separation
- •8.3.4 Drawing of nanofibers
- •8.3.5 Template synthesis
- •8.4 Biomedical applications of nanofibers
- •8.4.1 Wound dressing
- •8.4.2 Tissue engineering
- •8.4.3 In cancer therapy
- •8.4.4 Miscellaneous
- •8.5 Drug delivery application
- •8.5.1 Antihypertensive drug
- •8.5.2 Antimicrobial drug
- •8.5.3 Growth hormone
- •8.5.4 Miscellaneous
- •8.6 Conclusion
- •Keywords
- •References
- •Abstract
- •9.1 Introduction
- •9.2 Tissue engineering
- •9.3 Nanotechnology
- •9.4 Polymeric scaffolds in tissue engineering
- •9.5 Challenges
- •Keywords
- •References
- •Abstract
- •10.1 Introduction
- •10.2 Ideal properties of bioceramics
- •10.2.1 Mechanical property
- •10.2.2 Porosity, pore size, and shape
- •10.2.3 Biocompatibility and biodegradability
- •10.2.4 Osteoconductivity and osseointegrity
- •10.3 Bioceramics in orthopedic applications
- •10.4 Bioceramics in maxillofacial surgery
- •10.5 Bioceramic in drug delivery applications
- •10.6 Doped bioceramic in biomedical application
- •10.7 Conclusions
- •10.8 Future direction
- •Acknowledgments
- •Keywords
- •References
- •Index

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Advances in Pharmaceutical Technology for Drug Delivery Systems (PTDDS), Volume 2
KEYWORDS
• graphene
• graphene oxide
• reduced graphene oxide
• graphene quantum dots
• biomedical applications
• tissue engineering
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Advances in Pharmaceutical T echnology for Drug Delivery Systems (PTDDS), Volume 2: Recent Progress
in Biomedical Applications. Sougata Jana (Ed.)
© 2025 Apple Academic Press, Inc. Co-published with CRC Press (Taylor & Francis)
Nanotechnology in Gene Delivery
B. S. DHANYA
1
, and M. CHAMUNDEESWARI
2
1
Tamil Nadu, India
2
Chennai, India
CHAPTER 6
ABSTRACT
carbon nanotubes, liposomes, protein- and peptide-based nanoparticles, and
nanoscale polymeric materials can be used to develop these nonviral vectors.
biological systems.
6.1 INTRODUCTION
-

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gene delivery vectors that use genetic components such as DNA plasmids,
-
-
tions such as cancer, AIDS, and cardiovascular disorders, gene delivery
on the employing nanosystem (Hamimed et al., 2022). It appears that
gene therapy is crucial because in vivo gene delivery is thought to be

Nanotechnology in Gene Delivery
177
cardiovascular diseases, neurological disorders, and acquired autoim-
delivery systems (Pandit et al., 2022).
6.2 GENE DELIVERY
mediated gene silencing. RNAi is a phenomenon that happens in nature
the gene (Gaul et al., 2018). About 20–25 nucleotide duplex RNAs called
expression. By attaching to miRNA recognition sites in the 30 untranslated
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