Добавил:
Sekretar
kiopkiopkiop18@yandex.ru
t.me/Prokururor I Вовсе не секретарь, но почту проверяю
Опубликованный материал нарушает ваши авторские права? Сообщите нам.
Вуз:
Предмет:
Файл:Ординатура / Хирургия / Библиотека им академика М.И. Перельмана / Книга_5198_Библиотеки_им_академика_М_И_Перельмана.pdf
X
- •Foreword
- •Preface: Trauma as a Team Sport
- •Contents
- •History
- •Documented Outcomes
- •Future Direction
- •References
- •Humble Beginnings
- •A New Paradigm Is Born
- •References
- •3: Evidence Supporting Crisis Resource Management Training
- •Introduction
- •References
- •Introduction
- •The Trauma Team
- •Trauma Team Leadership
- •Crisis Resource Management
- •Observe, Orient, Decide, Act OODA Loop
- •Observe
- •Orient
- •Conclusion
- •References
- •Introduction: Why Does Teamwork Matter?
- •Introduction
- •Team Culture: Not Just Leaders; Followers Too
- •Crisis Communication 101
- •Conclusion
- •References
- •Background
- •Leadership Styles
- •Self-Awareness
- •Self-Management
- •Social Awareness
- •Relationship Management
- •Validation
- •Putting It All Together
- •References
- •7: Followership
- •Intro
- •What Is Followership
- •Why Is Followership Important?
- •Summary
- •References
- •Introduction
- •Situational Awareness
- •Situational Awareness: Level One
- •Situational Awareness: Level Two
- •Situational Awareness: Level Three
- •Attention
- •Stress
- •Conclusion
- •References
- •Handover Foundations
- •Handover Challenges
- •Handover Structure
- •Written Handover
- •Conclusion
- •References
- •10: Engaging Team Members
- •Respect
- •Resources
- •Engaging Virtual Teams
- •Virtual Water Cooler
- •Conclusion
- •References
- •Implicit Coordination
- •The Zero-Point Survey
- •Adaptive Coordination
- •Making It Happen
- •References
- •Acute Versus Chronic Stress
- •Recognizing Chronic Versus Acute Stress
- •Education Helps
- •Hyper-realistic Simulation Training
- •Resilience Is Individualized
- •Training Is Key
- •References
- •13: Stress Exposure Training
- •Introduction
- •Stress Training
- •Information Provision
- •Cognitive Control
- •Physiological Control
- •Overlearning
- •Mental Practice
- •Decision-Making
- •Team/Communication Skills
- •References
- •Introduction
- •Conclusions, Implications, Next Steps
- •References
- •15: Trauma Video Review
- •Introduction/What Is Trauma Video Review?
- •Team Simulation/Education
- •Performance Improvement
- •Research
- •Potential Barriers
- •Consent Processes
- •Other Considerations
- •Future Directions
- •Conclusion
- •References
- •Pre-arrival
- •Patient Arrival
- •Resuscitation
- •Pre-departure
- •Communication Skills
- •Structured Handovers
- •Conclusions
- •References
- •Origination
- •United States Prehospital System Legal Structure
- •Science Behind Prehospital Injury Patterns
- •Team Synergy vs Rock Star Player
- •Medical Errors
- •Controversy What Should Our System Implement
- •Training Quality
- •Active Killer
- •Realistic Training
- •Lessons Learned
- •Response
- •Nonmedical Personnel
- •Conclusion
- •References
- •Introduction
- •Future Direction
- •Conclusions
- •References
- •19: Prehospital Trauma
- •Introduction
- •Safety
- •Scene Assessment
- •Trauma Dynamics
- •Prehospital Ultrasound
- •Trauma Management: Tranexamic Acid (TXA) Administration
- •Conclusion
- •References
- •20: Transport Medicine
- •Introduction
- •The Trauma Clinical Network (TCN)
- •Direct Transport
- •Inter-hospital Transport
- •Emergency or Non-emergency Transportation
- •Monitoring During Transport
- •Conclusion
- •References
- •Introduction
- •Trauma Team Leader (TTL)
- •Airway
- •Respiratory Therapy
- •Emergency Medicine Physician
- •General Surgery
- •Orthopedic Surgery
- •Neurosurgery
- •Recording Nurse
- •Trauma Team Activation
- •The Trauma Bay
- •Trauma Team Function
- •Summary
- •References
- •22: Interprofessional Team Roles
- •References
- •23: The Trauma Bay Environment
- •Introduction
- •Surge Capacity
- •Decontamination
- •Communication
- •Control Center
- •Security Considerations
- •The Trauma Bay
- •Trauma Observation Unit Setup
- •Special Situations
- •Hybrid Operating Rooms
- •Conclusion
- •References
- •Introduction
- •Design
- •Formalizing Clinician-Designer-Builder Partnerships
- •A Human-Centered Approach
- •The Missing Link
- •Evidence-Based Design
- •Build
- •Train
- •Excel
- •Putting It Together
- •Summary
- •References
- •Introduction
- •Human Factor Analysis
- •Hybrid Operating Environment Lexicon
- •Summary
- •References
- •Introduction
- •Project Implementation
- •Results
- •Conclusion
- •Appendix A: Dam Tools Usability Testing Questionaire
- •References
- •Introduction
- •References
- •Introduction
- •Team-Based Principles
- •Continuous Improvement Processes
- •Conclusion
- •References
- •29: Trauma Resuscitation
- •Mechanisms
- •Neurologic Injury
- •Musculoskeletal Trauma Including Spine
- •Conclusions
- •References
- •30: Damage Control Resuscitation
- •Introduction
- •Massive Transfusion
- •Permissive Hypotension
- •Vascular Damage Control Techniques
- •Non-vascular Damage Control Techniques
- •Abdominal Compartment Syndrome
- •Open Abdominal Management
- •Damage Control Environments
- •References
- •Damage Control Part 1: Operative Intervention
- •Damage Control Part 2: Resuscitation
- •Damage Control Strategy Under Special Circumstances
- •Blast Injuries
- •Burns
- •Head Injury
- •Crush Injury
- •Conclusions
- •References
- •32: Trauma Team Decision-Making
- •Predictive Scores
- •Clinical Practice Guidelines (CPGs)
- •Trauma Team Leadership: Translating Decisions into Action
- •Future Directions: Toward High Reliability Organizing
- •Conclusions
- •References
- •33: Emergency Critical Care Procedures
- •Introduction
- •Airway Management
- •Tube Thoracostomy
- •Controversies
- •Antibiotics
- •Tube Selection
- •Occult Pneumothorax
- •Vascular Access
- •Peripheral Intravenous Access
- •Central Intravenous Access
- •Intraosseous Access
- •Ultrasound
- •Resuscitative Thoracotomy
- •Outcomes
- •Contraindications
- •Volume Expansion
- •Management
- •Diagnostic Peritoneal Lavage
- •Summary
- •References
- •Introduction
- •REBOA Programs
- •Partial REBOA
- •Intermittent REBOA
- •Vena Cava Occlusion
- •Tourniquets
- •Junctional Tourniquets
- •Abdominal Aortic Compression.
- •Hemostatic Agents
- •Topical Hemostatic Agents
- •Chemical Hemostatics
- •Physiologic Hemostatics
- •Hemostatic Dressings
- •Intra-abdominal Foam
- •Summary
- •References
- •What Is Interventional Radiology
- •Diagnostic Imaging Workup
- •Embolic Therapies
- •Gelfoam
- •Mural Repair
- •References
- •Non-verbal
- •Verbal
- •Wider Structural Perspective
- •Transferrable Solutions
- •Conclusion
- •References
- •Introduction
- •Pharmacotherapy
- •Paravertebral Block
- •Serratus Plane Block
- •References
- •Clinical Decision Support
- •Quality Improvement
- •Research
- •Trauma Systems
- •Conclusion
- •References
- •Outcomes
- •The Future
- •References
- •Introduction
- •Challenges
- •Provider Stress
- •Non-verbal Communication
- •Standardized Communication
- •Strategy 1: Scripted Procedures
- •Strategy 2: Structure Triage Tool
- •Conclusions
- •References
- •Introduction
- •Fetal Monitoring
- •Radiology
- •Conclusions
- •References
- •Introduction
- •Elderly Population
- •Psychiatric Comorbidities
- •Anticoagulated Patients
- •Conclusion
- •References
- •Introduction
- •Advanced Trauma Life Support (ATLS)—The Basics
- •Advanced TBI Guideline-Based Care
- •Noninvasive ICP/CPP Determination Methods
- •Brain Tissue Oxygen Monitoring (PbtO2)
- •Extracellular Brain Chemistry—Cerebral Microdialysis
- •Transcranial Doppler
- •Near-Infrared Spectroscopy
- •Continuous Electroencephalography (cEEG)
- •Cerebrovascular Reactivity Monitoring
- •Cerebral Compensatory Reserve
- •Individualized ICP Thresholds (iICP)
- •Integrating “Omics” into Acute Phase TBI Care—The Future
- •Conclusions
- •References
- •44: Basic Trauma Ultrasound
- •Introduction
- •The FAST Examination
- •Technique
- •Uses
- •Blunt Abdominal Trauma
- •Penetrating Trauma
- •Limitations
- •Summary
- •References
- •Introduction
- •Trauma Ultrasound Development
- •Pneumothorax
- •Musculoskeletal Ultrasound
- •Head Trauma
- •Contrast-Enhanced Ultrasound
- •Conclusions
- •References
- •Introduction
- •Imaging Modalities
- •Plain X-ray
- •Computed Tomography (CT) Scan
- •Other Modalities
- •Critical Thinking
- •References
- •Introduction
- •Initial Trauma CT Protocol
- •Iodinated Contrast Administration
- •Emergency Trauma MRI
- •References
- •48: Disaster Medicine
- •Natural or Man-made Disaster
- •The Disaster’s Cycle
- •Incident Command System
- •Triage
- •“Second Hit” Phenomenon
- •Conclusions
- •References
- •49: The Multi-casualty Trauma
- •Introduction
- •Historical Perspective
- •Prehospital Management
- •Triage
- •Pediatric Considerations
- •Intrahospital Management
- •Transfer Corridors
- •Blood Bank
- •Conclusions
- •References
- •Introduction
- •Crew Resource Management (CRM)
- •Resources
- •Review Process Including Logistics
- •Transactive Memory
- •Team Building (Before)
- •Team Performance (During)
- •Team Debrief (After)
- •Health
- •Fitness
- •Interagency Collaboration
- •Bystanders
- •Emergency Medical Services/Tactical EMS
- •Conclusions
- •References
- •Introduction
- •Improvised Explosive Device
- •Anti-police Violence
- •Improved Community Preparedness
- •Conclusions
- •References
- •Introduction
- •Procedures
- •Conclusions
- •References
- •Introduction
- •The MARCHE Algorithm Approach
- •Massive Hemorrhage Management (“M”)
- •Tourniquets
- •Wound Packing
- •Hemostatic Dressings
- •Junctional Tourniquets
- •Airway Management (“A”)
- •Respiration (“R”)
- •Circulation (“C”)
- •Vascular Access
- •Crystalloid
- •Hemostatic Resuscitation
- •Tourniquet Re-assessment
- •Hypothermia Prevention/Head Injury (“H”)
- •Hypothermia Management
- •Traumatic Brain Injury
- •Eye Injuries
- •Analgesia
- •Secondary Survey
- •Antibiotic Administration
- •Prolonged Field Care
- •Summary
- •References
- •Introduction
- •Hypothermia
- •Etiology
- •Pathophysiology
- •Lethal Triad (Diamond) Component
- •Treatment
- •Afterdrop
- •Resuscitation Progression
- •Prognosis
- •Team Dynamics
- •Conclusion
- •References
- •55: Burns
- •Incidence
- •Etiology
- •Prognosis
- •Initial Management: “ABCDE” Approach
- •Admission
- •Dressings
- •Nutrition
- •Multidisciplinary Recovery
- •Summary
- •References
- •War Zones
- •Casualty Care Team Preparation
- •Biological Weapons
- •Biological Warfare Historical Considerations
- •Personal Protective Equipment
- •Anthrax
- •Botulism Toxin
- •Conclusion
- •References
- •57: Nuclear Injuries
- •Introduction
- •Historical Background
- •Transportation
- •Hospital Care
- •Conclusions
- •References
- •Further Reading
- •Introduction
- •Historical Perspective
- •Parabolic Testing
- •Surgical Field Testing
- •Diagnostics
- •Immediate Damage Control Procedures
- •Conclusions
- •References
- •Introduction
- •Pandemic Impact
- •Financial Support
- •Conclusion
- •References
- •Introduction
- •Staff
- •Retraining/Reassignment
- •Consultants
- •Space/Structure
- •Trauma Bay
- •Operating Room
- •ICU or Floor
- •Clinic
- •Systems
- •Country Level
- •Regional Level
- •Hospital Level
- •Division or Trauma Team Level
- •Conclusion
- •References

58 Trauma andSurgical Capabilities forSpace Exploration
505
countries. Rural trauma in the United States shows that in
distant populations, mortality can be up to 50% greater than
urban populations. Trauma in rural populations accounts for
60% of deaths in the United States, despite only 20% of the
population reside in these areas [84–86].
Crewmembers in orbit are hemodynamically challenged
after 72h in a microgravity environment. They have about a
15% decrease in circulating red blood cells and plasma volume. This is dened as a class I hemorrhage terrestrially.
Another factor in space physiology that is unique is the
blunting of cardiovascular reexes. These combined result in
a decreased ability for a crewmember in microgravity to
respond to blood loss. This can result in a shortened time in
which intervention can have the greatest effect. They immediately move into a class II type of hemorrhagic shock. The
initial response to trauma must be rapid and consideration to
uid resuscitation must be given priority. As we have seen,
ATLS procedures can be readily accomplished in the microgravity environment [40]. Intravenous access has been demonstrated experimentally and aboard the ISS. Securing an
airway has also been demonstrated in parabolic ight using
endotracheal intubation, laryngeal mask insertion, or surgical tracheostomy. A FAST (focused assessment with sonography for trauma) ultrasound can be utilized to evaluate for
traumatic injury as well as conrm the endotracheal tube
position [87, 88].
The truncal region requires surgical intervention to control internal bleeding. External pressure is not efcacious to
control hemorrhage in this area. Ninety-nine percent of
deaths are due to thoracic or abdominal bleeding [89, 90].
Ultrasound has been used to localize intrapleural, intraperitoneal, and retroperitoneal bleeding terrestrially, in parabolic
ight and onboard space vehicles. It is as sensitive as
terrestrial- based applications [69–73, 91]. Management of
these injuries has changed due to rapid diagnostic procedures. No longer is explorative surgery required, and it has
given way to observation and repeated scanning techniques.
This also implies that surgical or intensive monitoring must
be available in case there is recurrent hemorrhage.
Observation may also be complicated by and require interventions in the cases of abscesses, pseudoaneurysms, urinomas, or biliomas. Many of these can be treated with
percutaneous interventions and have been demonstrated in
parabolic as well as actual spaceights [80, 92]. These conditions still require surgical expertise if severe recurrent
hemorrhage occurs. This would require specialized training
and physician intervention [3, 93]. In the space environment,
it may be better to intervene in a staged fashion rather than
going directly to open procedures. In all of these cases, anesthetics would be required. Gaseous anesthetics have innumerable problems in a closed-loop environment.
Re-inhalation and intoxication of the ones performing the
interventions is a real risk. Also the incorporation of anes-
thetic decontamination equipment into the environmental
control system may be space and cost prohibitive [3].
Intravenous anesthetic techniques are preferable and have
been demonstrated in parabolic ights.
Immediate Damage Control Procedures
Severe shock and sepsis may demand an immediate surgical
intervention before extensive diagnostics can localize the
condition. A group of ight surgeons, trauma surgeons, and
biomedical engineers emphasized that a laparotomy may be
required to stabilize a patient prior to further procedures or
deorbiting to Earth [94]. As discussed in Chaps. 30 and 31,
the paradigm of only completing the necessary components
via limited procedures is referred to as damage control (DC)
surgery. These methods do not require prolonged procedures
that tax the patient’s physiological reserves. Also these procedures do not require extensive equipment outlays [8, 95].
These procedures are not signicantly different from the terrestrial environment. Solid-organ bleeding can be tamponaded with packs around the offending organ. The abdominal
wall can be left open for further procedures to follow. An
open abdominal wall facilitates converting noncompressible
bleeding into compressible visceral bleeding by direct methods. Fibrin glue and tissue sealants can also be used easily in
these DC surgeries. These procedures have been demonstrated by physician extenders and non-surgeons [96]. These
types of procedures would allow immediate DC surgery to
be performed to stabilize the crewmembers’ condition. Then
planning and further diagnostics can take place with consultation with ground control. Then long-distance training or
reviews and simulations can be undertaken to perform a
denitive surgical procedure.
Orthopedic injuries lend themselves to damage control
procedures. Fixation devices are easy to use and may be the
most viable option. Plaster casting requires mixing plaster
with water, and this takes up a valuable resource. Fiberglass
casting materials produce large amounts of off-gassed products that must be accommodated by the environmental control system. These may not be easily removed. Flexible
aluminum splints and elastic bandages can be used on the
simpler fractures. Numerous fractures require gravity to heal
the break or maintain reduction. Manual traction is difcult
to apply in microgravity. Another concern is that bone healing is likely to be delayed in spaceight [13, 14]. External
xation offers numerous advantages. The techniques for the
most part are simple and rapid. They are not physiologically
stressing and do not require extensive anesthesia applications. Their application will allow early mobilization, and if
placed under tension, they may substitute for gravity and
manual traction. US can be used to diagnose and evaluate the
reduction [63, 97, 98]. This has been demonstrated in numer-

506
D. J. Alexander
ous studies [99–101]. The use of US can also be accomplished with external xation in place.
Addressing these surgical challenges has led to unique
solutions that have been incorporated into terrestrial care
[102, 103]. Currently, computerized tomography (CT) and
magnetic resonance imaging (MRI) are not done in microgravity environments. An MRI is possible as high-power
magnets have been incorporated into the ISS particle physics
experiments. The AMS-2 superconducting magnet has two
coils of niobium-titanium producing a central eld of 0.87
teslas. Numerous investigations are undergoing evaluation in
the use of advanced US techniques that could be incorporated in the treatment of critically injured patients. These
cover a range of subjects from diagnostic studies to addressing the crew training in advanced US techniques [47, 71, 82,
104]. The ISS has a US station aboard to conduct clinical and
research efforts in the microgravity environment. The carotid
intima-media thickness (CIMT) measurement was developed through a direct venture with NASA. CIMT uses the
ArterioVision software initially developed at NASA’s Jet
Propulsion Lab (JPL). JPL’s Image Processing Laboratory is
tasked with the processing and interpretation of spacecraft
imagery. NASA-invented Video Imaging Communication
and Retrieval software has been used to process pictures
from numerous space missions, including the Voyagers and
Mars Reconnaissance Orbiter. Periodic upgrades of the
imaging software have enabled greater accuracy and
improved knowledge of our solar system. ArterioVision is
incorporated into a standardized US examination of the
carotid artery and produces the CIMT [105].
Crew Medical Ocers
The CMO (crew medical ofcer) onboard the shuttle or ISS
is not required to be a physician. They undergo 40–60h of
medical training to accomplish specic diagnostic and therapeutic interventions [106]. This includes a broad area of
medical subjects, but they do not have the dedicated surgical
expertise that a trained physician possesses. A general surgeon with specic training in the unique diagnostic and therapeutic interventions for a long-duration mission would be
ideal. Other critical care or emergency physicians would also
be excellent candidates. This mission specialist physician
would also have other training in psychological support and
intervention for a long-duration spaceight. Their duties
would include nonmedical functions in order to equitably
distribute the workload of an extended mission. A caveat to
this is that the medical specialist would also have the same
physiological changes of microgravity and be susceptible to
the same risks as the other crewmembers. Another crewmember will need to have some redundancy in capability.
Telemedical support is available currently to the ISS, but will
be more difcult as the distances grow larger on interplanetary missions. Telemedicine and telerobotics research are
constantly ongoing to address many gaps in space medicine
care [104]. On these interplanetary missions, acute care will
need a large amount of autonomy and a large library of medical information available. Just in time computerized training
will need to be available. Also procedural simulation programs can be made available to practice and retain skills.
Each mission will have to be scrutinized, and specic
requirements and personnel assignments will have to be
made with the possibility of a critical medical event likely to
occur.
Conclusions
There are numerous advantages of low Earth orbit. In dealing with trauma, having easy communication access to
Mission Control and medical consultation resources offers
huge potentials. Another advantage is having the option of
deorbiting to more dedicated medical facilities. While initiatives to go further than the lunar surface are growing in reality, the option of an immediate return or easy communication
with terrestrial resources diminishes with increasing distance. The International Space Station offers unique opportunities to test interventional procedures in order to provide
care to traumatized or surgical patients. Landing on other
planetary surfaces also increases the risk or trauma due to
falls as well as construction injuries as support structures
will need to be erected. All of the exploration activities will
require dedicated planning to put in place dedicated trauma
treatment equipment and personnel. Training will also need
to be robust to cover these contingencies. We are explorers
and risk takers. In order to minimize the risk, we must plan
and test the future capabilities that will extend our reach
beyond our terrestrial bonds.

58 Trauma andSurgical Capabilities forSpace Exploration
Key Points
• Astronauts in microgravity have a decreased stroke
volume, reduced circulating blood volume, suppressed cellular immunity, and impaired wound
healing putting them at increased risk from trauma.
• Surgery in space faces many challenges including
providing and maintaining a sterile eld, maintaining hemostasis, and preventing contamination of
both the surgical eld and the surrounding
environment.
• Imaging in space is also limited and currently relies
heavily on ultrasound as the main imaging
modality.
• The mission specialist physician on long-duration
spaceights will face multiple challenges including
the performance of nonmedical functions in order
to equitably distribute the workload, the need for a
broad range of medical knowledge, and the ability
to retain a specialized surgical skill set with potentially minimal opportunities to practice.
References
1. Wilken DD.Signicant medical experiences aboard Polaris submarines: a review of 360 patrols during the period 1963–67, US
Naval Submarine Medical Center Report, 560, Groton; 1969.
2. Tansey WA, Wilson JM, Schaefer KE. Analysis of health data
from 10 years of Polaris submarine patrols. Undersea Biomed
Res. 1979;6(Suppl):S217–46.
3. Kirkpatrick AW, Campbell MR, Novinkov OL, et al. Blunt
trauma and operative care in microgravity: a review of microgravity physiology and surgical investigations with implications for
critical care and operative treatment in space. J Am Coll Surg.
1997;184:441–53.
4. Kirkpatrick AW, Dulchavsky SA, Boulanger BR, et al.
Extraterrestrial resuscitation of hemorrhagic shock: uids. J
Trauma. 2001;50:162–8.
5. Charles JB, Lathers CM.Cardiovascular adaptation to spaceight.
J Clin Pharmacol. 1991;31:1010–23.
6. Leach CS, Inners LD, Charles JB.Changes in total body water
during space ight. J Clin Pharmacol. 1991;31:1001–6.
7. McCuaig KE, Houtchens BA.Management of trauma and emergency surgery in space. J Trauma. 1992;33:615–25.
8. Burch JM, Ortiz JB, Richardson J, etal. Abbreviated laparotomy
and planned reoperation for critically ill patients. Ann Surg.
1992;215:476–83.
9. Buckey JC.Space physiology, Effect of spaceight on the cardiovascular system. NewYork: Oxford University Press; 2006.
p.149–54.
10. Kirkpatrick AW, Campbell MR, Broderick T, etal. Extraterrestrial
hemorrhage control: terrestrial developments in technique, technology, and philosophy with applicability to traumatic hemorrhage control during long duration spaceight. J Am Coll Surg.
2005;200:64–76.
11. Kirkpatrick AW, Ball CG, Campbell M, Williams DR, Parazynski
SE, Mattox KL, Broderick TJ.Severe traumatic injury during long
507
duration spaceight: light years beyond ATLS.J Trauma Manag
Outcomes. 2009;3:4.
12. Williams D, Kuipers A, Mukai C, Thirsk R. Acclimation
during space ight: effects on human physiology. CMAJ.
2009;180(13):1317–23.
13. Davidson JM, Aquino AM, Woodward SC, et al. Sustained
microgravity reduces intrinsic wound healing and growth factor
response in the rat. FASEB J. 1999;13:325–9.
14. Nicogossian AE, Sawin CF, Huntoon CL. Overall physiologic
response to spaceight. In: Nicogossian AE, Huntoon CL, Pool
SL, editors. Space physiology and medicine. Baltimore: Williams
& Wilkins; 1993. p.213–27.
15. Buckey JC.Bone loss: managing calcium and bone loss in space.
In: Barratt MR, Pool SL, editors. Space physiology. NewYork:
Oxford University Press; 2006. p.5–21.
16. Shackelford LC.Principles of clinical medicine for space ight,
Musculoskeletal response to space ight. New York: Springer
Science and Business Media; 2008. p.293–306.
17. Cann C. Response of the skeletal system to spaceight. In:
Churchill SE, editor. Fundamentals of space lifesciences, vol. 1.
Malabar: Krieger Publishing Company; 1997. p.83–103.
18. Tafton PG, McGough RL.Lower extremity fractures and dislocations. In: Moore EE, Feliciano DV, Mattox KL, editors. Trauma.
NewYork: McGraw-Hill; 2004. p.939–68.
19. Kaplansky A, Durnova G, Burkovskya T, et al. The effect of
microgravity o bone fracture healing in rats own on Cosmos
2044. Physiologist. 1991;34:325–9.
20. Taylor G, Janney R. In vivo testing conrms a blunting of the
human cell-mediated immune mechanism during spaceight. J
Leukoc Biol. 1992;48:129–32.
21. Kacena MA, Merrell GA, Manfredi B, etal. Bacterial growth in
space ight: logistic growth curve parameters for Escherichia coli
and Bacillus subtilis. Appl Microbiol Biotechnol. 1999;51:229–34.
22. Iaroshenko GL, Terent’ev VG, Mokrov MN.Peculiarities of surgical intervention under conditions of weightlessness. Voen Med
Zh. 1967;10:69–70.
23. Musgrave S. Surgical aspects of space ight. Surg Annu.
1976;8:1–23.
24. Stazhadze LL, Goncharov IB, Neumyzakin IP, etal. Anaesthesia,
surgical aid and resuscitation in manned space missions. Acta
Astronaut. 1981;8:1109–13.
25. Campbell MR, Billica RD, Johnston SL.Animal surgery in microgravity. Aviat Space Environ Med. 1993;64:58–62.
26. Campbell MR, Billica RD, Johnston SL. Surgical bleeding in
microgravity. Surg Gynecol Obstet. 1993;177:121–5.
27. McCuaig K. Aseptic technique in microgravity. Surg Gynecol
Obstet. 1992;175:466–47.
28. McCuaig K. Surgical problems in space: an overview. J Clin
Pharmacol. 1994;34:513–7.
29. Campbell MR, Billica RD, Melton S.Surgical instrument restraint
in weightlessness. Aviat Space Environ Med. 2001;72:871–6.
30. McCuaig K, Lloyd C, Gosbee J, etal. Simulation of blood ow in
microgravity. Am J Surg. 1992;164:114–23.
31. Barratt MR, Pool SL, etal. Chapter 15, Immunolgic concerns. In:
Principles of clinical medicine for space ight. Springer Science +
Business Media; 2008. p.307–31.
32. Campbell MR, Billica RD. A review of microgravity surgical
investigations. Aviat Space Environ Med. 1992;63(6):52.
33. Mutke HG.Equipment for surgical intervention and childbirth in
weightlessness. Aviat Space Environ Med. 1981;8:399–403.
34. Rock J.An expandable surgical chamber for use in a weightless
environment. Aviat Space Environ Med. 1984;55:403–4.
35. Markham SM, Rock JA.Deploying and testing an expandable
surgical chamber in microgravity. Aviat Space Environ Med.
1989;60:76–9.

508
D. J. Alexander
36. Markham SM, Rock JA.Microgravity testing of a surgical isolation containment system for space station use. Aviat Space
Environ Med. 1991;62:691–3.
37. Bennett TE, Pantalos GM, Sharp MK, Schurfranz T, Everett S,
Gillars K, O'Leary S, Lorange R, Woodruff S, Lemon M, Sojka
J.Effect of gravitational acceleration on cardiac diastolic function: the hearts in space project, 1985 to 1999. NASA Conference
Publication NASA/CP-1999-209476, Daelemans G, Mosier F,
editors, p.97–106; 1999.
38. Jay GD, Lee P, Goldsmith H, Battat J, Maurer J, Suner S.CPR
effectiveness in microgravity: comparison of three positions and a mechanical device. Aviat Space Environ Med.
2003;74(11):1183–9.
39. CAPT Zach Perkins, CPR in micro-gravity environments. http://
hypospray.thedocnetwork.net/?p=40.
40. Campbell MR, Billica RD, Johnston SL, Muller MS.Performance
of advanced trauma life support procedures in microgravity. Aviat
Space Environ Med. 2002;73(9):907–12.
41. Schweitzer EJ, Hauer JM, Swan KG, et al. Use of the
Heimlich valve in a compact autotransfusion device. J Trauma.
1987;27:537–42.
42. Mattox KL, Walker LE, Beall AC, etal. Blood availability for the
trauma patient—Autotransfusion. J Trauma. 1975;15(8):663–9.
43. Rumisek JD.Autotransfusion of shed blood: an untapped battleeld resource. Mil Med. 1982;147:193–6.
44. Kirkpatrick AW, Doarn CR, Campbell MR, Barnes SL, Broderick
TJ. Manual suturing quality at acceleration levels equivalent
to spaceight and a lunar base. Aviat Space Environ Med.
2008;79:1065–6.
45. Campbell MR, Williams DR, Buckey JC Jr, Kirkpatrick
AW.Animal surgery during spaceight on the Neurolab Shuttle
mission. Aviat Space Environ Med. 2005;76:589–93.
46. Jones JA, Johnston S, Campbell M, Miles B, Billica R.Endoscopic
surgery and telemedicine in microgravity: developing contingency procedures for exploratory class spaceight. Urology.
1999;53:892–7.
47. Campbell MR, Kirkpatrick AW, Billica RD, Johnston SL, Jennings
R, Short D, Hamilton D, Dulchavsky SA.Endoscopic surgery in
weightlessness: the investigation of basic principles for surgery in
space. Surg Endosc. 2001;15:1413–8.
48. Pinsolle V, Martin D, de Coninck L, Techoueyres P, Vaida
P. Microsurgery in microgravity is possible. Microsurgery.
2005;25:152–4.
49. Panait L, Merrell RC, Raq A, Dudrick SJ, Broderick TJ.Virtual
reality laparoscopic skill assessment in microgravity. J Surg Res.
2006;136:198–203.
50. Campbell MR, Billica RD, Jennings R, Johnston S 3rd.
Laparoscopic surgery in weightlessness. Surg Endosc.
1996;10:111–7.
51. Broderick TJ, Privitera MB, Parazynski SE, et al. Simulated
hand-assisted laparoscopic surgery (HALS) in microgravity. J
Laparoendosc Adv Surg Tech A. 2005;15:145–8.
52. Raq A, Broderick TJ, Williams DR, etal. Assessment of simulated surgical skills in parabolic ight. Aviat Space Environ Med.
2005;76:385–91.
53. Boffard KD, editor. Manual of denitive surgical trauma care,
Minimally invasive surgery in trauma. London: Hodder Headline
Group; 2003. p.172–3.
54. Leppaniemi A, Haapiainen R.Diagnostic laparoscopy in abdominal stab wounds: a prospective, randomized study. J Trauma.
2003;55:636–45.
55. Burch JM, Moore EE, Moore FA, etal. The abdominal compartment syndrome. Surg Clin N Am. 1996;76:833–42.
56. Kirkpatrick AW, Balogh Z, Ball CG, etal. The secondary abdominal compartment syndrome: Iatrogenic or unavoidable? J Am Coll
Surg. 2006;202:668–79.
57. Schein M, Wittman DH, Aprahamian CC, etal. The abdominal
compartment syndrome: the physiological and clinical consequences of elevated intra-abdominal pressure. J Am Coll Surg.
1995;180:745–52.
58. Kirkpatrick AW, Broderick T, Ball C, etal. Implications regarding the abdominal compartment syndrome in space. ANZ J Surg.
2005;75:A5–A60.
59. Holthausen UH, Nagelschmidt M, Troidl H.CO2 pneumoperitoneum: what we know and what we need to know. World J Surg.
1999;23:794–800.
60. Kirkpatrick AW, Keaney DVM, Kmet L, etal. Intra-abdominal
pressure effects on porcine thoracic compliance in weightlessness:
implications for physiologic tolerance of laparoscopic surgery in
space. Crit Care Med. 2009;37:591–7.
61. Holcomb JB, McClain JM, Pusateri AE, etal. Fibrin sealant foam
sprayed directly on liver injuries decreases blood loss in resuscitated rats. J Trauma. 2000;49:246–50.
62. Gunn J, Fehrenbacher P. Northwestern University, Chicago,
Illinois presentation at the NASA Human Research Program
Investigators’ Workshop 2014.
63. Taeger G, Ruchholtz S, Waydas C, etal. Damage control orthopedics in patients with multiple injuries is effective, time saving, and
safe. J Trauma. 2005;59:408–15.
64. Perchinsky MJ, Long WB, Hill JG, et al. Extracorporeal cardiopulmonary life support with heparin bonded circuitry in the
resuscitation of massively injured trauma patients. Am J Surg.
1995;169:488–91.
65. Vucevic M, Tehan B, Gamlin F, etal. The SMART needle: a new
Doppler ultrasound-guided vascular access needle. Anaesthesia.
1994;49:889–91.
66. Yaffe L, Abbott D, Schulte B.Smart aortic arch catheter: moving
suspended animation from the laboratory to the eld. Crit Care
Med. 2004;32:S51–5.
67. Amiko Nevills NEEMO: NASA extreme environment mission
operations report; 2006.
68. Marescaux J, Leroy J, Rubino F, et al. Transcontinental robotassisted remote telesurgery: feasibility and potential applications.
Ann Surg. 2002;235:487–92.
69. Kirkpatrick AW, Jones JA, Sargsyan A, Hamilton DR, Melton
S, Beck G, Nicolau S, Campbell M, Dulchavsky S. Trauma
sonography for use in microgravity. Aviat Space Environ Med.
2007;78:A38–42.
70. Kirkpatrick AW, Hamilton DR, Nicolaou S, Sargsyan AE,
Campbell MR, Feiveson A, Dulchavsky SA, Melton S, Beck
G, Dawson DL. Focused assessment with sonography for
trauma in weightlessness: a feasibility study. J Am Coll Surg.
2003;196:833–44.
71. Sargsyan AE, Hamilton DR, Jones JA, Melton S, Whitson PA,
Kirkpatrick AW, Martin D, Dulchavsky SA. FAST at MACH
20: clinical ultrasound aboard the International Space Station. J
Trauma. 2005;58:35–9.
72. Hamilton DR, Sargsyan AE, Kirkpatrick AW, Nicolaou S,
Campbell M, Dawson DL, Melton SL, Beck G, Guess T, Rasbury
J, Dulchavsky SA. Sonographic detection of pneumothorax
and hemothorax in microgravity. Aviat Space Environ Med.
2004;75:272–7.
73. Sargsyan AE, Karakitsos D.Ultrasound imaging in space ight.
In: Lumb, Karakitsos, editors. Critical care ultrasound. Elsevier;
2014. p.258–62.
74. Sargsyan AE, Hamilton DR, Nicolaou S, Kirkpatrick AW,
Campbell MR, Billica RD, Dawson D, Williams DR, Melton
SL, Beck G, Forkheim K, Dulchavsky SA.Ultrasound evaluation of the magnitude of pneumothorax: a new concept. Am Surg.
2001;67:232–5. Discussion pp235–6
75. Benninger MS, McFarlin K, Hamilton DR, Rubinfeld I, Sargsyan
AE, Melton SM, Mohyi M, Dulchavsky SA.Ultrasound evalua-

58 Trauma andSurgical Capabilities forSpace Exploration
509
tion of sinus uid levels in swine during microgravity conditions.
Aviat Space Environ Med. 2009;80:1063–5.
76. Riccabona M, Nelson TR, Pretorius DH. Three-dimensional
ultrasound: accuracy of distance and volume measurements.
Ultrasound Obstet Gynecol. 1996;7:429–34.
77. Shalev J, Davidi O, Fisch B.Quantitative three-dimensional sonographic assessment of pelvic blood after transvaginal ultrasoundguided oocyte aspiration: factors predicting risk. Ultrasound
Obstet Gynecol. 2004;23(2):177–82.
78. Catalano O, Cusati B, Nunziata A, et al. Active abdominal
bleeding: contrast-enhanced sonography. Abdom Imaging.
2006;31:9–16.
79. Hoyt DB. A clinical review of bleeding dilemmas in trauma.
Semin Hematol. 2004;41:S40–3.
80. Kirkpatrick AW, Nicolaou S, Campbell MR, Sargsyan AE,
Dulchavsky SA, Melton S, Beck G, Dawson DL, Billica RD,
Johnston SL, Hamilton DR.Percutaneous aspiration of uid for
management of peritonitis in space. Aviat Space Environ Med.
2002;73:925–30.
81. Fincke EM, Padalka G, Lee D, van Holsbeeck M, Sargsyan AE,
Hamilton DR, Martin D, Melton SL, McFarlin K, Dulchavsky
SA.Evaluation of shoulder integrity in space: rst report of musculoskeletal US on the International Space Station. Radiology.
2005;234:319–22.
82. Chiao L, Sharipov S, Sargsyan AE, Melton S, Hamilton DR,
McFarlin K, Dulchavsky SA. Ocular examination for trauma;
clinical ultrasound aboard the International Space Station. J
Trauma. 2005;58:885–9.
83. Simon JC, Sapozhnikov OA, Khokhlova VA, Wang Y-N, Crum
LA, Bailey MR, Ultrasonic atomization of tissue: a mechanism
for ultrasound-based surgery—presentation at the NASA Human
Research Program Investigators’ Workshop 2014, NIH grants
DK43881, EB007643 and NSBRI through NASA NCC 9–58.
84. Grossman DC, Kim A, MacDonald SC, et al. Urban-rural
differences in prehospital care of major trauma. J Trauma.
1997;42:723–9.
85. Mueller BA, Rivara FP, Bergman AB.Urban-rural location and
the risk of dying in a pedestrian-vehicle collision. J Trauma.
1988;28:91–4.
86. Sampalis JS, Denis R, Fréchette P, Brown R, Fleiszer D, Mulder
D.Direct transport to tertiary trauma centers versus transfer from
lower level facilities: impact on mortality and morbidity among
patients with major trauma. J Trauma. 1997;43(2):288–95.
87. Chun R, Kirkpatrick AW, Sirois M, et al. Where’s the tube?
Evaluation of hand-held ultrasound in conrming endotracheal
tube placement. Prehosp Disaster Med. 2004;19:366–9.
88. Weaver B, Lyon M, Blaivas M.Conrmation of endotracheal tube
placement after intubation using the ultrasound sliding lung sign.
Acad Emerg Med. 2006;13:239–44.
89. Martinowitz U, Holcomb JB, Pusateri AE, et al. Intravenous
rFVIIa administered for hemorrhage control in hypothermic
coagulopathic swine with grade V liver injuries. J Trauma.
2001;50:721–9.
90. Hoyt DB, Bulger EM, Knudson MM, etal. Death in the operating room: an analysis of a multi-center experience. J Trauma.
1994;37:426–32.
91. Melton S, Beck G, Hamilton D, etal. How to test a medical technology for space: trauma sonography in microgravity. McGill J
Med. 2001;6:66–73.
92. Demetriades D, Velmahos G.Technology-driven triage of abdominal trauma: the emerging era of nonoperative management. Annu
Rev Med. 2003;54:1–15.
93. Hiatt JR, Harrier HD, Koenig BV, et al. Nonoperative management of major blunt liver injury with hemoperitoneum. Arch Surg.
1990;125:101–3.
94. Houtchens B.System for the management of trauma and emergency surgery in space: nal report. NASA Johnson Space Center
NASA Grant NASW-3744 Houston.
95. Holcomb JB, Helling TS, Hirshberg A. Military, civilian, and
rural application of the damage control philosophy. Mil Med.
2001;166:490–3.
96. Tisherman SA, Vandevelde K, Safar P, etal. Future directions for
resuscitation research: ultra-advanced life support. Resuscitation.
1997;34:281–93.
97. Harwood PJ, Giannoudis PV, van Griensven M, etal. Alterations
in the systemic inammatory response after early total care and
damage control procedures for femoral shaft fracture in severely
injured patients. J Trauma. 2005;58:446–54.
98. Scalea TM, Boswell SA, Scott JD, etal. External xation as a
bridge to intramedullary nailing for patients with multiple injuries
and with femur fractures: damage control orthopedics. J Trauma.
2000;48:613–23.
99. Dulchavsky SA, Henry SE, Moed BR, et al. Advanced ultrasonic diagnosis of extremity trauma: the FASTER examination. J
Trauma. 2002;53:28–32.
100. Kirkpatrick AW, Brown R, Diebel LN, etal. Rapid diagnosis of
an ulnar fracture with portable hand-held ultrasound. Mil Med.
2003;168:312–3.
101. Noble VE, Legome E, Marshburn T.Long bone ultrasound: making the diagnosis in remote locations. J Trauma. 2003;54:800.
102. Grigorev AI, Bugrov SA, Bogomolov VV, Egorov AD,
Kozlovskaya IB, Pestov ID, Polyakov VV, Tarasov IK.Medicine
on Mars. UTMB Center for Aerospace Medicine; 2007.
103. Husted TL, Broderick TJ. NASA Medical results of the MIR
year-long mission. Course syllabus: pushing the envelope II.
and the emergence of new surgical technologies. J Surg Res.
2006;132:13–6.
104. Foale CM, Kaleri AY, Sargsyan AE, etal. Diagnostic instrumentation aboard ISS; just-in-time training for non-physician crewmembers. Aviat Space Environ Med. 2005;76:594–8.
105. NASA technology helps detect heart disease and strokes. Jet
Propulsion Laboratory. California Institute of Technology
[Internet] June 6, 2006. http://www.jpl.nasa.gov/news/news.
php?release=2007- 063.
106. Campbell MR.A review of surgical care in space. J Am Coll Surg.
2002;194:802–12.

Logistical Transformation ofHealthcare
Systems intheCOVID-19 Era
JaarA.Al-Tawq andZiadA.Memish
59
Introduction
Pandemics are characterized as being low-chance but highimpact events [1]. In recent years, we have witnessed the
emergence of three coronaviruses. These are the Severe
Acute Respiratory Syndrome Coronavirus (SARS-CoV)
detected in 2002in Guangdong Province, China [2, 3]. The
disease caused 8096 cases and 774 (9.6%) deaths over a
four-month period from late 2002 to early 2003 [4]. SARS
cases were detected in Vietnam, Hong Kong, Canada, the
United States, Ireland, Vietnam, and Singapore [2, 5–12],
and all cases were linked to a patient who stayed in Hotel M
in Hong Kong [13]. And 10 years later, a novel coronavirus
was isolated from a patient in Saudi Arabia [14, 15] which
was later named the Middle East Respiratory Syndrome
Coronavirus (MERS-CoV) [16].
The third coronavirus is the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is genetically
similar to SARS-CoV [17]. Initial cases were rst described
in a cluster of patients identied in December 2019in Wuhan
City, China. The initial cases were felt to be secondary to the
animal-human interaction, and subsequently, cases were the
result of community transmission [17, 18]. After the initial
cluster of cases was identied, several studies demonstrated
human-to-human transmission of SARS-CoV-2 through
either droplets or direct contact [19]. Subsequent cases
occurred among travelers from China and those caused local
transmission in almost every country around the globe [20,
21].
The Need forHealthcare Transformation
The need for healthcare transformation is well recognized
and emerged from the need to provide adequate and quality
healthcare to the patients. In previous studies in the United
States and without any stressful pandemics, only 55% (95%
CI: 54.3–55.5%) of adult patients received the recommended
care they needed [22]. The need for technology to change the
healthcare system had been recognized and was put in place
to drive such changes. In addition, it was suggested that it is
important to improve quality of care, decrease costs, and
build strategies across the continuum of care [23]. Of the key
components of transformation of healthcare are timing and
integral map that brings together the process of integration of
various components of behavior, social determinants, culture, and personal domains [24]. There is no better time to
drive such transformation than the time of the COVID-19
pandemic [24].
J. A. Al-Tawq
Specialty Internal Medicine and Quality Department, Johns
Hopkins Aramco Healthcare, Dhahran, Saudi Arabia
Indiana University School of Medicine, Indiana, IN, USA
Johns Hopkins University School of Medicine,
Baltimore, MD, USA
e-mail: jaffar.tawq@jhah.com
Z. A. Memish (*)
King Saud Medical City, Ministry of Health, Riyadh, Saudi Arabia
Al-Faisal University, Riyadh, Saudi Arabia
Hubert Department of Global Health, Rollins School of Public
Health, Emory University, Atlanta, GA, USA
© Springer Nature Switzerland AG 2025
L. Marshall Gillman, S. Widder (eds.), Trauma Team Dynamics, https://doi.org/10.1007/978-3-031-86312-7_59
Is COVID-19 anAccelerator ofor aGame
Changer inHealthcare?
Looking at the changes around the globe and specically in
the healthcare system during the COVID-19, it is thought
that COVID-19 was the cause for many of the changes.
However, others had thought that COVID-19 is an accelerator of these changes that were to happen regardless of the
occurrence of COVID-19. An example of these changes is
the use of telemedicine and telehealth (Fig.59.1).
511

512
TechnologyTelemedicine
Time
Changer
Tele-health
Fig. 59.1 COVID-19 time changer or an accelerator
Person
centered
technology
Accelerator
Pandemic Impact
Previous coronaviruses had caused signicant impact on the
healthcare systems [25, 26]. In addition, the pandemic has
shown many disparities not only in outcome but also in care
delivery among affected population [27]. The emergence of
COVID-19 pandemic resulted in a global disruption in
healthcare infrastructure with signicant increase in demand
on healthcare to care for the increasing surge of COVID-19
patients and maintaining the needed routine healthcare for
non-COVID-19 patients and protecting healthcare workers
and other patients [28–30]. There have been multiple
interventions to atten the curve and spare the healthcare
system. The lessons we learned from previous pandemics
were numerous. However, the current COVID-19 pandemic
is of particular importance due to the rapid and persistent
increased burden on healthcare organizations and the lack of
extra supplies needed to manage it on a global level. All
healthcare systems around the globe had to rapidly adopt
alternative options for dealing with COVID-19 and nonCOVID- 19 cases.
The emergence of COVID-19 necessitated the prevention
of the spread of infections in healthcare facilities by relying
on the United States Centers for Disease Control and
Prevention (CDC) strategies of hierarchy of infection prevention and controls [28, 31]. COVID-19 pandemic raised
the question about resilience of healthcare systems globally.
It is important that we look beyond the current crisis, build
on the capacity of healthcare systems to better prepare for
future outbreaks and pandemics, identify building blocks of
resilient health, and explore ways to build capacity and the
ability to maintain healthcare provision for non-COVID- 19related concerns. Many organizations had to also expand the
capacity for many activities such as intensive care units,
quarantine, isolation, and satellite clinics [32, 33]. Countries
around the globe have either used the SARS paradigm or the
J. A. Al-Tawq and Z. A. Memish
inuenza paradigm in dealing with COVID-19 [34]. The
SARS paradigm concentrated on eliminating infections, disease surveillance, redesigning of healthcare facilities, and
reducing cross-infection. The inuenza paradigm however is
based on acceptance that COVID-19 would ultimately spread
through the population and that little if any could be done to
control the disease [34].
The emergence of COVID-19 tested healthcare organizations for resilience by the ability to absorb the shock of
COVID-19, respond effectively, adapt to the shock, change
the structure of the organizations, and sustain day-to-day
operations. These are the fundamentals of any resilient organization [34]. In order for healthcare organizations to respond
to COVID-19 and any future pandemics, they must ensure
enough medical supplies, availability of workforce, having
additional needed nancial support, abilities to deal with
non-COVID-19-related issues (e.g., chronic medical conditions, cardiac cases, hemodialysis, and cancer care) [28], and
utilizing digital solutions and other innovations to monitor
and manage non-COVID-19 and COVID-19 patients.
Empowering Factors forIncreasing
Organization’s Capacity forImprovisation
There is the need to have organizations increase their improvisation through increasing autonomy, more exibility, fast
decision-making, and preserving structure with clear lines of
communication and coordination. Rather than materializing
“out of thin air,” improvisation comes from adjustments and
recombination of already existing resources to maintain
some structure [35]. For any organization to have a shared
understanding, especially of the way to deal with any pandemic, it is important to be fully aware of the interdependence on others, the need to have a holistic awareness of the
pandemic and the rapidity of the change, and have excellent
communication channels in order to share information in a
timely manner [36].
Shortage inManpower andPPEs/
Disinfectant
The emergence of COVID-19 had transformed the healthcare system across the globe [37, 38]. It is noted that there is
an international, national, and regional shortage of personal
protective equipment [39, 40]. The concern is confounded by
the fact that hospital administrators and managers prohibit
healthcare workers from discussing these issues openly or
raising the ag [41]. In a study from Saudi Arabia, about
one-third of respondents to questionnaires reported shortage
of PPE [42]. Another factor contributing to the shortage of
PPE is inappropriate use and wastage of PPE [43]. This

59 Logistical Transformation ofHealthcare Systems intheCOVID-19 Era
513
shortage is mainly for single-use PPE which is not designed
for reprocessing [44]. Thus, healthcare organizations developed multiple strategies to deal with this shortage including
custom-made production and sterilization or high-level disinfection for PPE reprocessing utilizing hydrogen peroxide
vapor or ultraviolet C waves [44]. However, manufacturers
may not recommend the disinfection or sterilization of respirators [44]. It was also noted that highly energetic ultraviolet
germicidal irradiation (UVGI) was effective for the reuse of
respirators [45]. Others had used face shields to provide coverage of the respirators and extended the use of such respirators. There was clear disruption of the supply across the
globe. China is the supplier of about 50% of surgical masks
and the only place that has the capacity of mass production
of clinical gowns [46]. On the other hand the United States is
the largest market for the use of PPE, and the acute increase
in the demand had contributed to the shortage [38]. To
address these issues, there is a global need to have extended,
reusable, and recyclable PPE [47].
Isolation andQuarantine
The COVID-19 pandemic had caused an urgent demand for
isolation rooms to isolate and quarantine individuals who
have infection or those who are suspected of being infected
for the duration of the incubation period. Quarantine originates from the Latin quadragina and the Italian quaranta
which denotes 40. This refers to the time when sailors had to
be managed offshore in their ships for 40days before being
allowed to get into the cities at the time of plague [48]. This
practice was used also during the previous coronaviruses
outbreaks. During the Severe Acute Respiratory Syndrome
Coronavirus (SARS-CoV) outbreak, many governments created quarantine facilities for those needing quarantine such
as close contacts and travelers [48]. In addition, during
SARS and the Middle East Respiratory Syndrome
Coronavirus (MERS-CoV) outbreak, healthcare workers
were quarantined after exposure [49, 50]. During COVID-19
pandemic, there had been multiple facilities created around
the globe to accommodate especially returning travelers for
quarantine [33, 51].
Telehealth andTelemedicine
It is no doubt that the COVID-19 pandemic had changed the
way healthcare workers had dealt with long-practiced medical therapies [28] such that patients with acute coronary syndrome were prioritized to receive nonsurgical interventions
such as thrombolytic therapy [52]. Telemedicine had become
increasingly utilized in many services such as 35% of urologic consultations [53]. Such visits allow healthcare staff to
assess the clinical progress of the patients, response to therapy, and adjust or rell medications [28].
Although telemedicine, telehealth, and e-health are used
interchangeably, there is a subtle difference between these
terms [54–56]. Telehealth encompasses telemedicine and utilizes any telecommunication tools such as texting, messaging, phone calls, e-mails, or other communication portals
allowing patient-to-provider communication. On the other
hand, telemedicine is a narrower term and refers to the use of
videoconferencing and remote patient monitoring. The term
e-health is being used to indicate data processing and computer applications. It seems that telemedicine is the most
commonly used terminology since the early 1990s, followed
by e-health, and the least used terminology is telehealth [54].
Despite the adaptation of telemedicine, there are several challenges that need to be kept in mind. These challenges include
availability of infrastructure, access, operational, regulatory,
communication, and legislative issues [57]. Of course, telemedicine poses opportunities and has its own challenges that
need further evaluation to ensure better utilization [58].
Leadership During theCOVID-19 Pandemic
The leadership style and activities during the COVID-19
pandemic had to adapt to making tough decisions without
clear and solid data, go beyond the unknown, communicate
effectively, integrate different activities and different hospitals, and deal with patient cohorting and staff shortages
(Fig.59.2). The initial events of the COVID-19 pandemic
were associated with lots of uncertainties and rapidly changing information. These uncertainties dictate that leaders
make decisions with less information and thus these decisions might not be optimal. These uncertainties many times
touch the basic needs of individuals to feel safe. Many
healthcare workers may act strangely and may not follow
appropriate infection control measures due to fear. Leaders
need to be equipped to move people from fear to actions to
deal with the situation that might be full of emotions and
irrational actions. Leaders need to change these situations
from fear to positive situations, to practice creative abandonment, and to communicate clear directions, actions, values,
and behaviors. This strategy allows actions to be gauged and
redirected to the best solution rather than not doing anything.
Leaders have to “Be First, Be Right, and Be Credible” in
their communications [59]. The communication has to be up,
down, and across for effective leadership [60]: upward communication to ofcials and governmental agencies, communicating down to staff and the community, and communicating
across to peers and other organizations [60]. However, such
leadership might be further challenged by the need to work
from home adding an additional factor and a burden in communication and management [61].

514
Fig. 59.2 A simplied
diagram of different activities
leaders of healthcare
organizations dealt with
during the COVID-19
pandemic
J. A. Al-Tawq and Z. A. Memish
Tough Decisions
Paents and
Staff
Management
Financial
Stability and
growth
Integraon
Leadership
Strategy
Dealing with
Unkowns
Communicaon
Stakeholders,
customers,
regulators
Financial Support
One of the most needed transformations in healthcare is to
have nancial support for the care of the patients, innovation,
maintaining research, and providing care for patients [37].
There were increasing demands on emergency room visits
and laboratory tests for COVID-19 with reduction in routine
surgical procedures and routine blood tests at the time of the
pandemic [62, 63]. The rapid evolution of the pandemic had
forced many healthcare organizations around the globe to
put and spend extra-nancial activities to maintain the
needed healthcare. The need to have enhanced partnerships
with governmental and private sectors for the development
of medications, vaccines, and diagnostic tests is fundamental
in the ght against this pandemic [37, 64].
Conclusion
The current COVID-19 pandemic resulted in a major inuence on healthcare organizations. This impact had accelerated the transformation of healthcare and impacted the
designs of hospitals to manage large inux of patients and
care for COVID-19 and non-COVID-19 patients. Healthcare
organizations should be in a better position to respond to
future challenges and emergencies including pandemics.

59 Logistical Transformation ofHealthcare Systems intheCOVID-19 Era
Key Points
• Pandemics are characterized as being low-chance
but high-impact events.
• The COVID-19 pandemic resulted in a global disruption in healthcare infrastructure.
• The COVID-19 pandemic caused an urgent demand
to isolate and quarantine individuals.
• Healthcare transformation is driven by need for
quality care.
• Integration of behavior, social determinants, culture, and personal domains is needed for the transformation of healthcare.
• COVID-19 is an accelerator of healthcare transformation including telemedicine, telehealth, and
e-health.
• Organizations need more autonomy, exibility, and
fast decision-making.
• Shortage in manpower and PPEs/disinfectant had a
signicant impact.
• Leadership adapting to tough decisions and
uncertainties.
• Financial support is needed for patient care, innovation, and research.
References
1. Lloyd-Smith M.The COVID-19 pandemic: resilient organisational
response to a low-chance, high-impact event. BMJ Lead [Internet].
2020 [cited 2021 Apr 16];4(3):109–12. Available from: http://
bmjleader.bmj.com/.
2. Lee N, Hui D, Wu A, Chan P, Cameron P, Joynt GM, etal. A major
outbreak of severe acute respiratory syndrome in Hong Kong. N
Engl J Med. 2003;348(20):1986–94.
3. Shaw K. The 2003 SARS outbreak and its impact on infection
control practices. Public Health [Internet]. 2006 [cited 2018 Feb
3];120(1):8–14. Available from: http://www.ncbi.nlm.nih.gov/
pubmed/16297415.
4. Graham RL, Baric RS.Recombination, reservoirs, and the modular spike: mechanisms of coronavirus cross-species transmission. J
Virol. 2010;84(7):3134–46.
5. Leung GM, Hedley AJ, Ho L-M, Chau P, Wong IOL, Thach TQ,
etal. The epidemiology of severe acute respiratory syndrome in
the 2003 Hong Kong epidemic: an analysis of all 1755 patients.
Ann Intern Med [Internet]. 2004 [cited 2016 Apr 8];141(9):662–73.
Available from: http://www.ncbi.nlm.nih.gov/pubmed/15520422.
6. Tsang KW, Ho PL, Ooi GC, Yee WK, Wang T, Chan-Yeung M,
etal. A cluster of cases of severe acute respiratory syndrome in
Hong Kong. N Engl J Med. 2003;348(20):1977–85.
7. Poutanen SM, Low DE, Henry B, Finkelstein S, Rose D, Green
K, et al. Identication of severe acute respiratory syndrome
in Canada. N Engl J Med [Internet]. 2003 [cited 2017 Jan
18];348(20):1995–2005. Available from: http://www.ncbi.nlm.nih.
gov/pubmed/12671061.
8. Centers for Disease Control and Prevention (CDC). Outbreak of
severe acute respiratory syndrome—worldwide, 2003. MMWR
Morb Mortal Wkly Rep [Internet]. 2003 [cited 2019 Oct
515
12];52(11):226–8. Available from: http://www.ncbi.nlm.nih.gov/
pubmed/12665115.
9. Centers for Disease Control and Prevention (CDC). Preliminary
clinical description of severe acute respiratory syndrome.
MMWR Morb Mortal Wkly Rep [Internet]. 2003 [cited 2019 Oct
12];52(12):255–6. Available from: http://www.ncbi.nlm.nih.gov/
pubmed/12680522.
10. Centers for Disease Control and Prevention (CDC). Update:
severe acute respiratory syndrome—United States, June 4, 2003.
MMWR Morb Mortal Wkly Rep [Internet]. 2003 [cited 2019 Oct
12];52(22):525–6. Available from: http://www.ncbi.nlm.nih.gov/
pubmed/12803200.
11. Centers for Disease Control and Prevention (CDC). Severe acute
respiratory syndrome (SARS) and coronavirus testing—United
States, 2003. MMWR Morb Mortal Wkly Rep [Internet]. 2003
[cited 2019 Oct 12];52(14):297–302. Available from: http://www.
ncbi.nlm.nih.gov/pubmed/12731699.
12. Centers for Disease Control and Prevention (CDC). Severe acute
respiratory syndrome—Singapore, 2003. MMWR Morb Mortal
Wkly Rep [Internet]. 2003 [cited 2019 Oct 12];52(18):405–11.
Available from: http://www.ncbi.nlm.nih.gov/pubmed/12807088.
13. Parashar UD, Anderson LJ.Severe acute respiratory syndrome:
review and lessons of the 2003 outbreak. Int J Epidemiol [Internet].
2004 [cited 2019 Oct 12];33(4):628–34. Available from: http://
www.ncbi.nlm.nih.gov/pubmed/15155694.
14. Zaki AM, van Boheemen S, Bestebroer TM, Osterhaus ADME,
Fouchier RAM.Isolation of a novel coronavirus from a man with
pneumonia in Saudi Arabia. N Engl J Med [Internet]. 2012 [cited
2016 Jan 17];367(19):1814–20. Available from: http://www.ncbi.
nlm.nih.gov/pubmed/23075143.
15. Corman VM, Eckerle I, Bleicker T, Zaki A, Landt O, EschbachBludau M, etal. Detection of a novel human coronavirus by realtime reverse-transcription polymerase chain reaction. Euro Surveill
[Internet]. 2012 [cited 2019 May 10];17(39). Available from: http://
www.ncbi.nlm.nih.gov/pubmed/23041020.
16. de Groot RJ, Baker SC, Baric RS, Brown CS, Drosten C, Enjuanes
L, et al. Middle East respiratory syndrome coronavirus (MERSCoV): announcement of the Coronavirus Study Group. J Virol
[Internet]. 2013;87(14):7790–2. Available from: https://pmc.ncbi.
nlm.nih.gov/articles/PMC3700179/pdf/zjv7790.pdf.
17. Guan W, Ni Z, Hu Y, Liang W, Ou C, He J, etal. Clinical characteristics of coronavirus disease 2019in China. N Engl J Med.
2020;382(18):1708–20.
18. Zhou F, Yu T, Du R, Fan G, Liu Y, Liu Z, et al. Clinical course
and risk factors for mortality of adult inpatients with COVID-19in
Wuhan, China: a retrospective cohort study. Lancet [Internet]. 2020
[cited 2020 Mar 17];6736(20):1–9. Available from: http://www.
ncbi.nlm.nih.gov/pubmed/32171076.
19. Lai CC, Shih TP, Ko WC, Tang HJ, Hsueh PR.Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus
disease-2019 (COVID-19): the epidemic and the challenges. Int J
Antimicrob Agents. Elsevier B.V. 2020;55:105924.
20. Zhao D, Yao F, Wang L, Zheng L, Gao Y, Ye J, etal. A comparative study on the clinical features of coronavirus 2019 (COVID- 19)
pneumonia with other pneumonias. Clin Infect Dis [Internet].
2020 [cited 2020 May 25];71(15):756–61. Available from: https://
pubmed.ncbi.nlm.nih.gov/32161968/?from_single_result=10.1093
%2Fcid%2Fciaa247&expanded_search_query=10.1093%2Fcid%
2Fciaa247.
21. Peeri NC, Shrestha N, Rahman MS, Zaki R, Tan Z, Bibi S, etal.
The SARS, MERS and novel coronavirus (COVID-19) epidemics,
the newest and biggest global health threats: what lessons have we
learned? Int J Epidemiol. 2020;49(3):717–26.
22. McGlynn EA, Asch SM, Adams J, Keesey J, Hicks J, DeCristofaro
A, et al. The quality of health care delivered to adults in the
United States. N Engl J Med [Internet]. 2003 [cited 2021 Apr
Соседние файлы в папке Библиотека им академика М.И. Перельмана
