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Biomedical EPR Part-B Methodology Instrumentation and Dynamics - Sandra R. Eaton

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Contents of Previous Volumes

445

Chapter 4

Shift-Reagent-Aided NMR Spectroscopy in Cellular, Tissue, and

Whole-Organ Systems

Sandra K. Miller and Gabriel A. Elgavish

Chapter 5

In Vivo NMR

Barry S. Selinski and C. Tyler Burt

Chapter 6

In Vivo NMR Studies of Cellular Metabolism

Robert E. London

Chapter 7

Some Applications of ESR to in Vivo Animals Studies and EPR Imaging

Lawrence J. Berliner and Hirotada Fujii

VOLUME 12

Chapter 1

NMR Methodology for Paramagnetic Proteins

Gerd N. La Mar and Jeffrey S. de Ropp

Chapter 2

Nuclear Relaxation in Paramagnetic Metalloproteins

Lucia Banci

Chapter 3

Paramagnetic Relaxation of Water Protons

Cathy Coolbaugh Lester and Robert G. Bryant

Chapter 4

Proton NMR Spectroscopy of Model Hemes

F. Ann Walker and Ursula Simonis

446

Contents of Previous Volumes

Chapter 5

Proton NMR Studies of Selected Paramagnetic Heme Proteins

J. D. Satterlee, S. Alam, Q. Yi, J. E. Erman, I. Constantinidis, D. J. Russell, and S. J. Moench

Chapter 6

Heteronuclear Magnetic Resonance: Applications to Biological and Related Paramagnetic Molecules

Joël Mispelter, Michel Momenteau, and Jean-Marc Lhoste

Chapter 7

NMR of Polymetallic Systems in Proteins

Claudio Luchinat and Stefano Ciurli

VOLUME 13

Chapter 1

Simulation of the EMR Spectra of High-Spin Iron in Proteins

Betty J. Gaffney and Harris J. Silverstone

Chapter 2

Mössbauer Spectroscopy of Iron Proteins

Peter G. Debrunner

Chapter 3

Multifrequency ESR of Copper: Biophysical Applications

Riccardo Basosi, William E. Antholine, and James S. Hyde

Chapter 4

Metalloenzyme Active-Site Structure and Function through Multifrequency CW and Pulsed ENDOR

Brian M. Hoffman, Victoria J. DeRose, Peter E. Doan,

Ryszard J. Gurbiel, Andrew L. P. Houseman, and Joshua Telser

Chapter 5

ENDOR of Randomly Oriented Mononuclear Metalloproteins: Toward Structural Determinations of the Prosthetic Group

Jürgen Hüttermann

Contents of Previous Volumes

447

Chapter 6

High-Field EPR and ENDOR in Bioorganic Systems

Klaus Möbius

Chapter 7

Pulsed Electron Nuclear Double and Multiple Resonance Spectroscopy of Metals in Proteins and Enzymes

Hans Thomann and Marcelino Bernardo

Chapter 8

Transient EPR of Spin-Labeled Proteins

David D. Thomas, E. Michael Ostap, Christopher L. Berger, Scott M. Lewis, Piotr G. Fajer, and James E. Mahaney

Chapter 9

ESR Spin-Trapping Artifacts in Biological Model Systems

Aldo Tomasi and Anna Iannone

VOLUME 14

Introduction: Reflections on the Beginning of the Spin Labeling Technique

Lawrence J. Berliner

Chapter 1

Analysis of Spin Label Line Shapes with Novel Inhomogeneous Broadening from Different Component Widths: Application to Spatially Disconnected Domains in Membranes

M. B. Sankaram and Derek Marsh

Chapter 2

Progressive Saturation and Saturation Transfer EPR for Measuring Exchange Processes and Proximity Relations in Membranes

Derek Marsh, Tibor Páli, and László Horváth

Chapter 3

Comparative Spin Label Spectra at X-band and W-band

Alex I. Smirnov, R. L. Belford, and R. B. Clarkson

448

Contents of Previous Volumes

Chapter 4

Use of Imidazoline Nitroxides in Studies of Chemical Reactions: ESR Measurements of the Concentration and Reactivity of Protons, Thiols, and Nitric Oxide

Valery V. Khramtsov and Leonid B. Volodarsky

Chapter 5

ENDOR of Spin Labels for Structure Determination: From Small Molecules to Enzyme Reaction Intermediates

Marvin W. Makinen, Devkumar Mustafi, and Seppo Kasa

Chapter 6

Site-Directed Spin Labeling of Membrane Proteins and Peptide-

Membrane Interactions

Jimmy B. Feix and Candice S. Klug

Chapter 7

Spin-Labeled Nucleic Acids

Robert S. Keyes and Albert M. Bobst

Chapter 8

Spin Label Applications to Food Science

Marcus A. Hemminga and Ivon J. van den Dries

Chapter 9

EPR Studies of Living Animals and Related Model Systems

(In-Vivo EPR)

Harold M. Swartz and Howard Halpern

Appendix

Derek Marsh and Karl Schorn

VOLUME 15

Chapter 1

Tracery Theory and NMR

Maren R. Laughlin and Joanne K. Kelleher

Contents of Previous Volumes

449

Chapter 2

Isotopomer Analysis of Glutamate: A NMR Method to Probe Metabolic Pathways Intersecting in the Citric Acid Cycle

A. Dean Sherry and Craig R. Malloy

Chapter 3

Determination of Metabolic Fluxes by Mathematical Analysis of Labeling Kinetics

John C. Chatham and Edwin M. Chance

Chapter 4

Metabolic Flux and Subcelluar Transport of Metabolites

E. Douglas Lewandowski

Chapter 5

Assessing Cardiac Metabolic Rates During Pathologic Conditions with Dynamic NMR Spectra

Robert G. Weiss and Gary Gerstenblith

Chapter 6

Applications of Labeling to Studies of Human Brain Metabolism

In Vivo

Graeme F. Mason

Chapter 7

In Vivo NMR Spectroscopy: A Unique Approach in the Dynamic Analysis of Tricarboxylic Acid Cycle Flux and Substrate Selection

Pierre-Marie Luc Robitaille

VOLUME 16

Chapter 1

Determining Structures of Large Proteins and Protein Complexes by NMR

G. Marius Clore and Angela M. Gronenborn

450

Contents of Previous Volumes

Chapter 2

Multidimensional NMR Methods for Resonance Assignment, Structure Determination, and the Study of Protein Dynamics

Kevin H. Gardner and Lewis E. Kay

Chapter 3

NMR of Perdeuterated Large Proteins

Bennett T. Farmer II and Ronald A. Venters

Chapter 4

Recent Developments in Multidimensional NMR Methods for Structural Studies of Membrane Proteins

Francesca M. Marassi, Jennifer J. Gesell, and Stanley J. Opella

Chapter 5

Homonuclear Decoupling to Proteins

Hiroshi Matsuo, and Gerhard Wagner

Chapter 6

Pulse Sequences for Measuring Coupling Constants

Geerten W. Vuister, Marco Tessari, Yasmin Karimi-Nejad, and Brian Whitehead

Chapter 7

Methods for the Determination of Torsion Angle Restraints in Biomacromolecules

C. Griesinger, M. Hennig, J. P. Marino, B. Reif, C. Richter, and H. Schwalbe

VOLUME 17

Chapter 1

Aspects of Modeling Biomolecular Structure on the Basis of Spectroscopic or Diffraction Data

Wilfred F. van Gunsteren, Alexandre M. J. J. Bonvin, Xavier Daura,

and Lorna J. Smith

Contents of Previous Volumes

451

Chapter 2

Combined Automated Assignment of NMR Spectra and Calculation of Three-Dimensional Protein Structures

Yuan Xu, Catherine H. Schein, and Werner Braun

Chapter 3

NMR Pulse Sequences and Computational Approaches for Automated Analysis of Sequence-Specific Backbone Resonance Assignments of Proteins

Gaetano T, Montelione, Carlos B. Rios, G. V. T. Swapna, and Diane E. Zimmerman

Chapter 4

Calculation of Symmetric Oligomer Structures from NMR Data

Seán I, O’Donoghue and Michael Nilges

Chapter 5

Hybrid–Hybrid Matrix Method for 3D NOESY–NOESY Data Refinements

Elliott K. Gozansky, Varatharasa Thiviyanathan, Nishantha Illangasekare, Bruce A. Luxon, and David G. Gorenstein

Chapter 6

Conformational Ensemble Calculations: Analysis of Protein and Nucleic Acid NMR Data

Anwer Mujeeb, Nikolai B. Ulyanov, Todd M. Billeci, Shauna Farr-Jones, and Thomas L. James

Chapter 7

Complete Relaxation and Conformational Exchange Matrix (CORCEMA) Analysis of NOESY Spectra of Reversibly Forming Ligand–Receptor Complexes: Application to Transferred NOESY

N. Rama Krishna and Hunter N. B. Moseley

Chapter 8

Protein Structure and Dynamics from Field-Induced Residual Dipolar Couplings

James H. Prestegard, Joel R. Tolman, Hashim M. Al-Hashimi,

and Michael Andrec

452

Contents of Previous Volumes

Chapter 9

Recent Developments in Studying the Dynamics of Protein Structures from and Relaxation Time Measurements

Jan Engelke and Heinz Rüterjans

Chapter 10

Multinuclear Relaxation Dispersion Studies of Protein Hydration

Bertil Halle, Vladimir P. Denisov, and Kandadai Venu

Chapter 11

Hydration Studies of Biological Macromolecules by Intermolecular WaterSolute NOEs

Gottfried Otting

VOLUME 18

Chapter 1

Introduction to in Vivo EPR

Harold M. Swartz and Lawrence J. Berliner

Chapter 2

Principles of in Vivo EPR

Sankaran Subramanian, James B. Mitchell, and Murali C. Krishna

Chapter 3

Frequency and Power Considerations for in Vivo EPR and Related Techniques

James M. S. Hutchison

Chapter 4

CW EPR Signal Detection Bridges

Janusz Koscielniak

Chapter 5

Resonators for Low Field in Vivo EPR

Kenneth A. Rubinson

Contents of Previous Volumes

453

Chapter 6

Principles of Imaging: Theory and Instrumentation

Periannan Kuppusamy, Michael Chzhan, and Jay L. Zweier

Chapter 7

Time-Domain Radio Frequency EPR Imaging

Sankaran Subramanian, James B. Mitchell, and Murali C. Krishna

Chapter 8

Stable Soluble Paramagnetic Compounds

Howard J. Halpern

Chapter 9

Stable Particulate Paramagnetic Materials as Oxygen Sensors in EPR

Oximetry

R. B. Clarkson, Paul Peroke, Shong-Wan Norby, and B. M. Odintsov

Chapter 10

Packaging of Stable Paramagnetic Materials in Oximetry and Other

Applications

Bernard Gallez

Chapter 11

Spin Trapping in Vivo: Facts and Artifacts

Graham S. Timmins and Ke Jian Liu

Chapter 12

Ex Vivo Detection of Free Radical Metabolites of Toxic Chemicals and Drugs by Spin Trapping

Ronald P. Mason and Maria B. Kadiiska

Chapter 13

Chemistry and Biology of Nitric Oxide

Andrei M. Komarov

454

Contents of Previous Volumes

Chapter 14

In Vivo and in Vitro Detection of NO by EPR

Hirotada Fujii and Lawrence J. Berliner

Chapter 15

The Measurement of Oxygen in Vivo Using in Vivo EPR Techniques

Harold M. Swartz

Chapter 16

Cardiac Applications of in Vivo EPR Spectroscopy and Imaging

Jay L. Zweier, Alexandre Samouilov, and Periannan Kuppusamy

Chapter 17

Applications of in Vivo EPR Spectroscopy and Imaging in Cancer

Research

Howard J. Halpern

Chapter 18

Applications of in Vivo EPR Spectroscopy and Imaging to Skin

Jürgen Fuchs, Norbert Groth, and Thomas Herrling

Chapter 19

Pharmaceutical Applications of in Vivo EPR

Karsten Mäder and Bernard Gallez

Chapter 20

Proton–Electron Double–Resonance Imaging (PEDRI)

David J. Lurie

Chapter 21

Combining NMR and EPR/ESR for in Vivo Experiments

Jeff F. Dunn and Harold M. Swartz

Chapter 22

Potential Medical (Clinical) Applications of EPR: Overview and

Perspectives

Harold M. Swartz