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S. Bao et al.

6.2 Virtual Surgical Instruments

Surgical simulation refers to the use of a variety of medical image data and virtual reality technology to create a simula­tion environment on a computer. Surgeons use the informa­tion in the virtual environment to perform surgical planning and training and to guide the actual operation. During the virtual surgery process, the cutting tools and the surgical instruments are needed for operation simulation, such as sur­gical scissors, hemostatic forceps, and suture. The PHANTOM from SensAble Technologies are used to pro­vide an excellent graphical user interface, and various kinds of virtual surgical instruments are developed in combination with GHOST SDK, a 3D interactive tactile environment development kit of PHANTOM.After importing the recon­structed STL le, the 3D objects of the bile duct, artery, and vein were obtained and combined to simulate the operation of incision and suture.

6.2.1 Geometric Modeling

The geometric model of the liver is obtained from the previ­ous 3D reconstruction and imported into the virtual surgical platform through program reading. The STL model is a geo­metric model with a triangular set to represent the shape of the outer contour of the object. In the tactile frame of GHOST SDK, the model is transformed into the triangular mesh model required by GHOST SDK by programming. In order to speed up the calculation of collision response and to inte­grate the computational force feedback algorithm (developed in-house), it is necessary to initialize the topological infor­mation of the 3D model, that is, to complete some calcula­tion work when the program is initialized. Then the necessary information is called directly during the movement of the virtual surgical instruments to establish an indexed triangle mesh.
In the indexed triangle mesh, we maintain two lists: the vertices and triangles. Each vertex contains a 3D position, as well as additional information about its geometric attributes (colors and textures) and physical characteristics (hardness and friction coefcient) to facilitate real-time extraction in an interactive simulation. Each triangle points to its three vertices. These vertices are listed in counterclockwise order, and the surface normal vector should be precalculated. Compared with triangular arrays, the use of indexed triangu­lar mesh has the following advantages:
• Space-efcient. Its integer vertex index is much smaller
than the vertex repetition rate in a triangular array.
• Implicit adjacent topology information. Although the side
information is not directly stored, the public side can be
found by searching the triangle table.
Reference to the actual surgical instruments, geometric modeling of surgical instruments was performed by using the Open Graphics Library (OpenGL) software development kit and 3D graphics software. Surgical instruments cannot be simply constructed by basic elements supported by OpenGL, and the use of 3DMAX improves the realism of model render­ing. 3D geometries are exported into 3D Studio (3DS) format by 3DMAX.Finally, by using OpenGL for graphics program­ming, the 3DS format model is generated into an OpenGL display list and thus improve OpenGL performance (Fig.6.1)

6.2.2 Motion Modeling

Virtual surgical instruments are introduced into the recon­structed 3D object to perform various surgical procedures including cutting, dissecting, and clamping. 3D objects in the simulation system consist of two categories: one is 3D objects with a tactile interface, such as virtual surgical instru­ments; the other is common 3D objects that constitute the
Fig. 6.1 Instruments constructed by 3D Studio MAX. (a) Scalpel; (b) Scissors
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virtual scene, such as abdominal viscera and biliary tissue. For the latter, the geometric transformation functions that are available in OpenGL can be applied for coordinate transfor­mations such as translation and rotation. A tree structure is used to describe the hierarchical nature of the objects. The exposed triangles of the liver and its internal vessels corre-
Fig. 6.2 Motion modelling. (a) Simulated liver; (b) hepatic vein incision; (c) Suture of hepatic veins
a
a
spond to the leaf nodes of the tree. These triangles specify the geometrical properties of leaf nodes and their direction and proportion relative to the parent node. Any transforma­tion applied to the parent node will automatically affect its leaf nodes. The motion of all objects is constrained and con­trolled in this way (Fig.6.2).
b
b
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Fig. 6.2 (continued)
c
The PHANTOM interface corresponding to the virtual surgical instruments is a particular type of 3D object. In the servo loop, the status information of the PHANTOM device (such as position and orientation) can be queried by the call­back function. The orientation of the PHANTOM stylus is described by a 4×4 homogeneous coordinate transformation matrix.
In addition, the motion modeling of virtual surgical instruments also needs graphics and PHANTOM correction. In the 3D simulation, the view of the virtual camera and workspace of PHANOM should be aligned to immerse the user who participates in the virtual surgery. Therefore, the workspace of PHANTOM needs to be centered on the Z-axis of the visual body. PHANTOM’s workspace should be located between the clipping planes of the observation cone so that objects of interest can appear on the screen. This is achieved by placing the PHANTOM workspace in the center of the virtual camera and moving it along Z-axis. In order to be able to move the surgical instruments within the screen area to the graphical objects mapped to PHANTOM. It is also necessary to calculate the scaling factor of the PHANTOM working scope.

6.2.3 Physical Modeling

Collision detection has been the focus and one of the funda­mental problems in surgical simulation. Only when surgical instruments collide with human tissues, is it necessary to perform cutting and suturing procedures. Since the model of organs and tissues is required to be as elaborate as possible, the number of triangles generally reaches 10,000 to 100,000. In order to improve the detection efciency, a point-to-body collision detection method is used. The particles represent the moving virtual surgical instrument, and triangles repre­sent the static organ and tissues.
The virtual surgical instrument (PHANTOM lever) is in contact with the virtual object only at the tip of the stylus, and from this point, the force is fed back to the user’s hand through the operating lever. The specic description is as fol­lows: judge whether the tip of the stylus passes through the object in the scenario according to the motion information of the PHANTOM handle. If intersection is determined, the feedback force can be further calculated based on the point of intersection with the object. The movement of the handle is usually small, relative to the frequency of the tactile feed-
New position
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Original position
Surface
Grid-based operation
Fig. 6.3 Grid-based needle operation
back, which means that each frame only needs to check a relatively small spatial area. In the accurate collision detec­tion phase, the built-in algorithm of the development kit can be used to determine whether the tip of the surgical instru­ment has collided. For specic collision information (such as the triangle index of the collision and its vertex), the calcula­tion is simplied by the method of vertex/triangle collision.
In the actual operation, surgeons usually adopt a variety of surgical instruments for collaborative operation, and hence the collision detection between surgical instruments is essential. Since the model of various surgical instruments are relatively simple, and they do not deform during operation. In order to improve the authenticity of such detection, a free 3D collision detection library (ColDet) is used to achieve body-to-body collision detection (Fig.6.3).
When the surgeon manipulates the surgical instrument to interact with the 3D object surface, a reaction force is felt at collision. PHANTOM’s particle-spring-damper force feed­back model can be used for liver physics simulation. Springs and dampers are attached to the surface of the soft tissue. In a virtual environment, a vertex of a virtual surgical instru­ment model will undergo elastic deformation once it collides with the surface. By obtaining a vector of the original posi­tion and the new position of a vertex of the instrument model, the intersection contact point (SCP) of the soft tissue surface can be obtained, and the length of the spring stretching can also be obtained to calculate the surface elasticity (Fig.6.4).
Foreign virtual surgery systems are expensive. However, there is no medical image processing and virtual surgery sys­tem for abdominal and thoracic surgery in China, and no simulation environment is provided. The simulation system has only partial functionality for force feedback and does not provide a realistic simulation of the operating environment. Also, the production of viscera and visceral surgical software involves a considerable amount of data and calculations. The
damping
Fig. 6.4 Diagram of force feedback model
spring
methods to achieve the rapid reconstruction, arbitrary cut­ting, soft tissue deformation, and the software development and hardware conguration of human–computer interaction of the existing methods remain as problems to be solved.

6.3 Surgical Simulation

With the interdisciplinary integration and rapid development of computer technology, image processing technology, med­ical physics, and medicine; the methods of surgical diagnosis and treatment are undergoing rapid changes. The computed­aided surgery system and the simulation surgery system devised in recent years are the results of the rapid develop­ment and application of information science in the medical eld. Simulated surgery refers to the application of virtual human research results on the “virtual human” surgery by using simulated surgical instruments (scalpels, hemostats) in the virtual surgery environment. Surgeons can use these advanced technical means as the preoperative, intraopera­tive, and postoperative auxiliary support for real surgery to make the surgery safer, more reliable, more accurate, and less invasive.
Current research on simulation surgery mainly focuses on neurosurgery, plastic surgery, and orthopedics; especially in intraoperative navigation, which combines virtual reality with augmented reality; and even the successful application of surgical robots in clinical practice. However, there are few clinical reports in the eld of hepatobiliary and pancreatic surgery, which are limited to the preoperative study or evalu­ation of liver surgery. For example, Bro-Nielsen etal. used liver data from the VHP male dataset to study the reconstruc­tion of the liver and simulate the surgical plane of the liver by nite element method (Bro-Nielsen et al. 1996). They believed that the 3D reconstruction of the liver contributes to the understanding of the liver anatomy, and it is possible to realize the preoperative planning, training, and teaching of
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liver surgery. Wigmore etal. used 3D models reconstructed from computed tomography angioportography (CTAP) images in clearly displaying the hepatic and portal veins. Twenty-seven patients undergoing hepatobiliary surgery were retrospectively studied. By comparing tumor volume, total liver volume, and functional liver volume to body weight, it was found that functional liver volume was strongly correlated to body weight, and the risk of postopera­tive liver failure could be well predicted (Wigmore et al.
2001).
At present, liver surgery remains one of the most chal-
lenging operations, mainly because of the complexity and variability of the internal organ structure. Therefore, the establishment of the liver surgery program often depends on the operator’s precise understanding of the 3D spatial rela­tionship between the intrahepatic vascular biliary tree and the lesion. However, anatomical variation and deformity, tumor extrusion inltration, and previous liver resection can cause changes in the spatial relationship of the intrahepatic biliary vascular tree; so, it is often challenging to develop accurate surgical plans. It is also difcult to accurately deter­mine the variation type, branch direction, location, size, and geometry of the lesion and the spatial relationship between the lesion and the surrounding ductal system by observing the traditional 2D image. Moreover, since visible light can­not penetrate human tissues and the internal structures that have not yet been cut cannot be seen and felt, it is difcult to obtain the spatial information of the individual anatomical structure of the patient’s liver. Due to the lack of a quantita­tive description of the tissues involved in the operation, intra­operative exploration combined with traditional 2D images cannot adequately meet the needs of liver surgery. Doctors can only rely on experience to plan for liver surgery blindly, which inevitably leads to inaccuracy in the location of the operation space. Moreover, it is impossible to accurately for­mulate the operation path and avoid the risks of surgery, which will undoubtedly affect the quality, increase trauma, and prolong the duration of surgery. Meanwhile, because 2D images cannot accurately calculate the liver volume, and for patients with varying degrees of liver cirrhosis, it is difcult to choose between preserving enough residual liver volume and completely removing the lesion. The rapid development of modern medical image technology and computer technol­ogy, especially the appearance of 3D image visualization reconstruction technology, provides an opportunity to solve the above problems. 3D image visualization reconstruction technology is called non-injurious stereoscopic anatomy technology. Its principle is to use computer image processing technology to analyze and process traditional 2D slice images, to realize 3D reconstruction and display of the seg­mentation and extraction of human organs, soft tissues, and
lesions, to simplify the cognitive process of the human brain on 2D images, to further intuitively and accurately display the full range of stereo information of the liver and its piping systems and lesions. The 3D image visualization reconstruc­tion technology can assist the physician to analyze the lesions and other areas of interest qualitatively and quantitatively, which signicantly improves the accuracy and reliability of medical diagnosis. It can provide accurate, individualized anatomical information for the design of the surgical plan, so it has a more signicant clinical application value than tradi­tional two-dimensional tomography.
On the other hand, although the emergence of the 3D digi­tal model of the liver has dramatically deepened the sur­geon’s understanding of liver anatomy as well as the spatial relationship between lesions and intrahepatic ducts, pancreas and peripancreatic tissues, the clinical expectation of hepato­biliary and pancreatic surgery is to develop a comprehensive simulation system suitable for clinical needs. Hepatobiliary and pancreatic surgeons can use it to practice repeatedly, familiarize themselves with the surgical procedures, improve surgical skills, and shorten time to competency. It can also be used to carry out new operations and to learn from the old and improve the operation, reduce the trauma of the opera­tion, preserve the function of the liver, and improve patients’ quality of life after the operation.
The surgical simulation system requires that the target object model and the simulated surgical instrument must have both high-quality realistic visual images, and real-time interaction of high-resolution, Life-like haptic feedback (force feedback). The visual feedback refers to observing the realistic virtual environment through the display and the real-time deformation of the simulated body under the oper­ation of the interactive device; the tactile feedback means that the operator perceives the physical characteristics of the simulated body through the interactive device. Fidelity refers to the degree of the recreation of the whole structure and behavior of the simulation object and the capacity of the sys­tem simulation object. In the visual simulation surgery sys­tem, in order to ensure a real-time experience from the simulation process, the graphics refresh frequency of no less than 30Hz is required, and the force feedback refresh fre­quency is not less than 1000Hz. Tactile feedback is a two­way exchange of information with the user, while the visual feedback is one way. When the user exerts an external force on the virtual model, the data is transmitted to the interface controller. The master computer calls the graph drawing soft­ware to change the virtual environment and relay the posi­tional and tactile feedback information to the user. Any virtual reality system is restricted by its temporal and struc­tural authenticity, which is mainly determined by its hard­ware structure and software composition.
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6.3.1 The Hardware System

Hardware devices include the main computer graphics work­station, display device, and the PHANTOM Force feedback device. The computing requirements to run the PHANTOM device are a computer with at least a 2 core 2GHz processor, 2GB available RAM, 512MB Hard drive, and a high-speed connection (IEEE 1394a rewire). it mainly completes the tasks of simulation calculation and graphics rendering. Of the two tasks, the simulation calculation involves the display of virtual environment, collision detection, force feedback calculation, and tactile interaction. The display equipment mainly completes visual feedback between the operator and the virtual environment. The PHANTOM Force feedback device is an essential tool for users to interact with simula­tion systems. Through PHANTOM, the space position and motion direction of “surgical instruments” (force feedback device joystick) controlled by the operator can be input into the system. At the same time, after the host computer com­pletes collision detection and forces feedback calculation, tactile feedback is provided to the operator by PHANTOM, so that the surgeon can perceive the delicate features of the object and the resistance of the object to the force. The prod­uct “PHANTOM” with a 3D force feedback function devel­oped by SensAble Company, is used as a tactile interactive device, and the model is PHANTOM Desktop. The PHANTOM product, developed at the Massachusetts Institute of Technology in the United States, has led several patents. Among them, PHANTOM Desktop provides a real-
istic 3D force feedback function for users with its rst-class design.
Moreover, the device’s universal design makes it compat­ible with operating systems running on ordinary microcom­puters. This interactive device is different from the previous tactile device. Its portable design and compact base bring exibility for users and avoids the disadvantages of the tradi­tional device, such as large volume, skeleton mechanical structure, noise, and joystick vibration in the tactile device. In terms of design, due to sufcient consideration of the gen­eral working application environment, this type of equip­ment is connected to the computer through extended parallel port (EPP) and is equipped with a general 110/220v AC power supply (Fig.6.5).
The accepted criteria for measuring the quality of a tac­tile feedback device are low inertia, low lag, high reverse drive capability, extensive force range, high mechanical signal bandwidth, and suitable workspace. PHANTOM Desktop is a 6-DOF force feedback manipulator with joint coordinates, which can send instruction information to six directions of rotation and can also feedback the force infor­mation to X, Y, and Z directions. In other words, the user can perceive and manipulate the 3D simulation body built in the virtual environment through the joystick or nger sleeve of the PHANTOM end, and feedback tactile infor­mation to users. Its fundamental performance indicators and relevant parameters are shown in Table6.1, which can fully meet the needs of tactile interaction in virtual abdomi­nal surgery.
a b c
Fig. 6.5 The hardware system of surgery simulation. (a) Computer host; (b) display of the simulation system; (c) PHANTOM (the force feedback device)
Table 6.1 Parameters of PHANTOM
Resolution Maximum force Rigidity Force feedback Stylus inertia Degree of freedom
0.023mm 7.9N 3.16N/mm x, y, z 45g x, y, z, yaw, pitch, roll
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6.3.2 Software System

The software system is the core of the surgical simulation system. Through this system, various types of surgical simu­lations are available, and feedback can be provided accord­ing to the simulation results. All calculations related to visual and tactile feedback can be completed by the software sys­tem. By using a tactile development kit that is compatible with PHANTOM (Fig.6.6), a virtual tactile environment can be easily established. The software development environ­ment is the Visual C ++ platform. The design languages and the development kit of the virtual environment mainly include OpenGL, GHOST, and OpenHaptics SDKs.
6.3.2.1 FreeForm Modeling System
FreeForm Modeling System is a force feedback virtual real­ity system developed by SensAble Technologies, Inc. The system can be used in conjunction with PHANTOM.Although the FreeForm system is powerful and can simulate the virtual liver surgery after research, it still has some certain drawbacks:
• Virtual liver surgery requires not only surgical tools but also instruments such as surgical scissors, vascular for­ceps, sutures, which are currently not available in the FreeForm system.
• FreeForm is not a native virtual surgery system, and its expansibility is limited. Its interface and related functions need to be improved. Professor Fang’s research group has independently built a virtual reality software solution.
6.3.2.2 Open Graphics Library
A virtual surgical instrument with high delity is designed in the system, this “virtual instrument” can then be manipulated through the PHANTOM handle to simulate the surgical pro­cesses, such as liver cutting. Real-time force feedback can be
Fig. 6.6 The liver is being cut with PHANTOM
generated by real-time cutting and suture of the liver, and the force can be felt concurrently. The Open Graphics Library (OpenGL) is strictly dened as “a software interface to graphics hardware.” In essence, it is a fully portable and fast 3D graphics and modeling library. OpenGL is a software interface that uses specialized graphics processing hardware to support users’ graphics and image manipulation for high­quality 3D objects. OpenGL sets patterns, determines the graph element, and describes other OpenGL operations by transferring instruction in the form of functions or procedure calls. The primary work used to create graphics is to organize a nite number of polygons whose objects are composed of vertices in three dimensions. It consists of hundreds of pro­cedures and functions that developers can use to build 3D models and interact in 3D real time. Most OpenGL systems require at least one frame buffer in the graphics hardware system. OpenGL’s graphics functions do not require devel­opers to write 3D object model data into a xed data format. In this way, developers can not only use their data but also use data sources in other different formats, such as les in 3DS format. This exibility dramatically saves development time and improves the developmental benets of the software.
6.3.2.3 Tactile Development Kit
General haptics open software toolkit SDK (GHOST SDK) is an object-oriented C++ toolkit, which allows users to dene the geometry, physical properties, and tactile effects of emulators according to their needs. OpenHaptics is the successor to the GHOST SDK. Virtual instruments devel­oped with OpenHaptics are all oriented to PHANTOM force feedback devices, and their programs function well. The OpenHaptics development kit utilizes the OpenGL API, which is very familiar to graphics developers. With the OpenHaptics development kit, developers can use existing OpenGL code to develop special geometric applications, or they can use OpenHaptics commands to set tactile properties of materials, such as friction and hardness. Its extensible architecture allows developers to add support for new shape types. It is also possible to integrate other library les such as physics/kinematics and collision detection engines. The OpenHaptics development kit supports devices ranging from low-cost PHANTOM Omni to larger PHANTOM Premium haptic devices. Software developers can use the SensAble OpenHaptics development kit to add tactile and accurate 3D navigation features in a wide range of areas.
The visual simulation surgery system uploads the liver and its internal conduit model reconstructed by MI-3DVS abdominal 3D reconstruction software into the FreeForm Modeling System and uses virtual cutting software and PHANTOM force feedback devices to manipulate virtual surgical instruments to cut, clamp and stitch the liver model. The Visual simulation surgery system is not only an
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excellent liver simulation surgery environment system with immersion, interaction, and force feedback, but also a sys­tem that can easily realize the simulation research of all kinds of surgery in other organs of hepatobiliary and pan­creatic surgery. At present, this system is being commer­cialized step by step and has been applied preliminarily in the clinic.
6.3.3 Development andApplication ofVirtual Surgical Instruments
The above-reconstructed model is introduced into the SensAble’s FreeForm 3D Modeling System for necessary modication such as denoising, smoothing, automatic spatial registration, and color matching. The reconstructed image is realistic in shape, and the operator can combine, rotate, set the transparent or opaque display of multiple models, or hide any organs and blood vessels for observation. The smoothed model is observable, and the morphological and spatial ana­tomical relationship is the same as the real human body. It can meet the requirements of the next auxiliary diagnosis and simulation surgery.
Surgical simulation is implemented in a virtual surgical instrument simulation system (software copyright 105,978). The virtual surgical instrument simulation system consists of hardware and software systems. The virtual surgical plat­form is constructed by using the hardware of the main work­station and force feedback equipment, and the GHOST SDK software development kit used to develop the virtual surgery platform. A complete range of simulated surgical instru­ments (Fig.6.7) was made, including scalpel, surgical scis­sors, hemostatic forceps, needle holder, surgical needle, suture, retractor, bile duct probe, skin forceps, electric knife, ultrasonic knife, and drainage tube.
6.3.4 Signicance ofLiver Virtual Simulation
Surgery
The Liver Visualization Simulation Surgery System is a vir­tual environment system for hepatectomy based on the self­developed 3D system of abdominal medical images (MI-3DVS) combined with the FreeForm Modeling System. It mainly aims at liver tumor resection simulation, using a computer and other techniques to analyze and process two­dimensional medical image data; and to provide realistic medical images and simulated surgical process and results. It can be used to simulate similar resections of other organs, such as biliary tract, pancreas, spleen, and other diseases. The results are preliminary, and there is still a lot of work to be done, such as adding a measurement module to measure the volume of the liver and the excised liver, as well as the size and length of the hepatic duct structure; adding a liver
function evaluation module to evaluate postoperative liver function, the risk of operation, and the quality of life accord­ing to the parameters of the liver function examination; add­ing the evaluation module of surgical skills to provide a comprehensive evaluation of the skills, process, and the result of the virtual operation.
The Liver Visual Simulation Surgery System has the advantages of interoperability, intervention, arbitrariness, and repeatability. It can simulate the cutting process in advance without performing surgery and predict complex and dangerous situations that are expected to occur in actual surgery. For example, when the segmentation level involves important blood vessels or bile ducts in the liver, or there a risk of injury. Under these circumstances, the corresponding adjustment should be adopted. By comparing the advantages and disadvantages of various programs through the simula­tion of different surgical programs, a reasonable individual­ized surgical plan is formulated, and necessary preventive measures can be taken in advance. The system not only helps to preserve the integrity of residual hepatic vessels and nec­essary important structures, minimize the incidence of post­operative complications, and increase the success rate of surgery: but also can accurately measure the total volume of liver, the volume of lesion, the volume of functional liver, the volume of the resection and residual liver; thus predicting the risk of postoperative liver failure.
Currently, the liver visualization simulation surgery sys­tem only simulates the rough process of liver surgery. However, it has reected the characteristics of liver surgery, such as preoperative liver resection line, separation of liver tissue, cutting of hepatic vessels, and removal of hepatobili­ary tumors and diseased liver. Of course, there are still many vital technical challenges to be solved:
• The recognition of liver internal pipeline structure in liver
image is called image segmentation. Due to the unobvi-
ous boundary between various duct structures, hepatobili-
ary tumors, and liver parenchyma in some CT images, the
angiography can only make individual structures stand
out, and the images cannot clearly show all four liver
tubes (especially intrahepatic bile ducts) and the adjacent
relationship between the tumor and the internal structure
of the liver. Thus, utterly automatic segmentation by the
software is impossible, and manual intervention is
required. Even the effect of manual intervention is not
completely satisfactory.
• The structure of the liver varies. How to apply specic
data and a virtual “standard liver” model with image
fusion technology to reect the specicity and individual-
ity of the liver; so as to achieve the preoperative planning
of specic patients with hepatobiliary tumor, preoperative
targeted training, and further improve the surgical plan,
increase the success rate of actual surgery and reduce the
complications of surgery; remains a problem.
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d
e
f
Fig. 6.7 Simulated surgical instruments. (a) Simulated scalpel handle; (b) simulated stone forceps; (c) simulated surgical scissors; (d) simula­tion of needle holder and suture operation; (e) simulated laparoscopic
instruments; (f) simulated electric knife; (g) simulated surgical suture needle; (h) simulated tissue forceps; (i) simulated operating scalpel
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g
i
h
Fig. 6.7 (continued)
• The liver is a highly active organ in the human body. How to combine virtual reality with augmented reality remains a problem. It means valid linking of the “virtual liver” established by the patient’s actual CT scan data, the patient’s human body and the surgical instruments in the laparoscopic surgery or the surgical robot operation; to navigate surgery, reduce injury, improve the success rate, and reduce the complications of the operation.
• How to realistically reproduce the scenes and feelings of an actual operation in a virtual operation, is a question that needs to be solved, including vascular injury bleed­ing, soft tissue deformation, different sensations when the separation of different tissues occur, and a series of force feedback issues such as the different force required to cut different tissues. Clearly, this is a highly technical prob­lem, which needs further research.
6.4 Application of3D Visualization Virtual Simulation Surgery inBiliary Surgery
The development of modern science and technology is increasingly reecting the intersection and connectedness of multiple disciplines. Virtual reality (VR) is a high-tech con­cept developed in recent years. It is an interdisciplinary, inte­grated technology involving elds such as computer graphics, human–computer interaction technology, sensing technol­ogy, articial intelligence, and cognitive science. It uses the computer to form sensations such as realistic three­dimensional visual, auditory and tactile perception, enabling people to experience and communicate with the virtual world through appropriate devices. In the past 10 years, virtual reality technology has exerted an increasingly important