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106 Wild Edible Plants
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A. Denham, & M. Whitelegg (Eds.), Medical Herbs (pp. 211– 220). Churchill Livingstone. https:// doi.org/ 10.1016/ B978- 0- 443- 10344- 5.00026- 4
Topouzova- Hristova, T., Moskova- Doumanova, V., Keremidarska, M., Doumanov, J., Miteva,
G., Petkova, B., & Kapchina- Toteva, V. (2012). Anticancer effect of plant extracts from Lamium album L. by induction of cell death in vitro. Science & Technologies, 2(1), 55– 59. www.sustz.com/ jour nal/ Volum eII/ Numb er1/ Pap ers/ Topouz ova- Hrist ova.pdf
Usmani, A., & Almoselhy, R. I. M. (2024). Current trends in Nigella sativa L. (Black seed) from
traditional to modern medicine with advances in extraction, formulation, quality control, regulatory status, and pharmacology. International Journal of Pharmaceutical Chemistry and Analysis, 11(1), 11– 23. https:// doi.org/ 10.18231/ j.ijpca.2024.002
Uwineza, P. A., Urbaniak, M., Stępień, Ł., Gramza- Michałowska, A., & Waśkiewicz, A. (2023).
Lamium album ower extracts: A novel approach for controlling Fusarium growth and mycotoxin biosynthesis. Toxins, 15(11), 651. https:// doi.org/ 10.3390/ TOX INS1 5110 651/ S1
Vergun, O. M., Grygorieva, O. V., Brindza, J., Shymanska, O. V., Rakhmetov, D. B., Horčinová-
Sedlačková, V., Korablova O. A., Fishchenko, V. V., & Ivanišová E. (2019). Content of phen­olic compounds in plant raw of Cichorium intubus L., Lamium purpureum L. and Viscum album L. Plant Introduction, 83(3), 87– 96. https:// doi.org/ 10.5281/ ZEN ODO.3404 149
Voșgan, Z., Dumuța, A., Mihali, C., Dippong, T., Mihalescu, L., Marian, M., & Mihalescu,
B. (2024). The inuence of different forms of black cumin (Nigella sativa L.) on the characteristics of sheep’s curd cheese. Frontiers in Sustainable Food Systems, 8, 1– 16. https:// doi.org/ 10.3389/ fsufs.2024.1413 008
Wang, X., Jiang, A., & Batra, V. (2020). Severe thrombocytopenia associated with black seed
oil and evening primrose oil. Cureus, 12(6), e8390. https:// doi.org/ 10.7759/ CUR EUS.8390
Wirkowska- Wojdyła, M., Chmiel, M., Ostrowska- Ligęza, E., Górska, A., Bryś, J., Słowiński, M.,
& Czerniszewska, A. (2021). The inuence of interesterication on the thermal and techno­logical properties of milkfat- rapeseed oil mixture and its potential use in incorporation of model meat batters. Applied Sciences, 11(1), 1– 12. https:// doi.org/ 10.3390/ APP1 1010 350
Yang, R., Zhang, L., Li, P., Yu, L., Mao, J., Wang, X., & Zhang, Q. (2018). A review of chemical
composition and nutritional properties of minor vegetable oils in China. Trends in Food Science & Technology, 24, 26– 32. https:// doi.org/ 10.1016/ j.tifs.2018.01.013
Yimer, E. M., Tuem, K. B., Karim, A., Ur- Rehman, N., & Anwar, F. (2019). Nigella sativa
L. (Black cumin): A promising natural remedy for wide range of illnesses. Evidence- Based Complementary and Alternative Medicine: ECAM, e1528635. https:// doi.org/ 10.1155/ 2019/ 1528 635
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V. M. (2014). Revealing the reviving secret of the white dead nettle (Lamium album L.). Phytochemistry Reviews, 2(13), 375– 389. https:// doi.org/ 10.1007/ S11 101- 014- 9356- 2
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powder for Helicobacter pylori infected patients: A randomized, double- blinded, placebo­controlled clinical trial. BMC Complementary Medicine and Therapies, 23(1), 123. https:// doi.org/ 10.1186/ s12 906- 023- 03955- 4
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Wild Edible Plants in the Manufacturing of Bakery/Meat Products 107
Zeković, Z., Cvetanović, A., Švarc- Gajić, J., Gorjanović, S., Sužnjević, D., Mašković, P., Savić,
S., Radojković, M., & Ðurović, S. (2017). Chemical and biological screening of stinging nettle leaves extracts obtained by modern extraction techniques. Industrial Crops and Products, 108, 423– 430. https:// doi.org/ 10.1016/ J.INDC ROP.2017.06.055
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The Catnip Plant for Beverage
4
Production
Olesia Priss, Tetiana Kolisnychenko, and Nadiia Zahorko
4.1 INTRODUCTION
The global food system continues to face disruptions caused by pandemics and wars. The number of people affected by hunger in 2022 ranged from 691 to 783 millions worldwide (FAO et al., 2023). Alongside critical food shortages, there is also a serious exacerbation of the “hidden hunger” problem. Hidden hunger derives from diets that provide sufcient calories but do not provide enough vitamins and minerals, and is a lethal factor affecting both developed and developing countries (Gödecke et al., 2018). Expanding the range of plant- based products in the diet allows necessary vitamins, micronutrients, amino acids, and other phytonutrients essential for normal human functioning to be obtained. However, out of thousands of plant and animal species cultivated or grown for food in the past, fewer than 200 currently make a signicant contribution to global food production, with only nine contributing to 66% of total crop production. Today, approximately 30 agricultural crops provide 95 percent of human energy needs, and 75 percent of global food production is based on 12 commercial crops and ve animal species (Hunter et al., 2019). Thus, tens of thousands of edible plant species remain undervalued and underutilized and can be used to address global food security issues (Chivenge et al., 2015). In this context, the use of edible wild plants holds great promise. Forgotten and underutilized species have excellent nutritional value for addressing micronutrient deciencies (Li et al., 2020) and other valuable phytonutrients (Priss et al., 2023; Vasheka & Petrusha, 2022). The use of underutilized plants helps combat problems associated with malnutrition and serves as a source for producing dietary supplements, developing new food products with enhanced nutritional value
108
DOI: 10.1201/9781003486794-4
The Catnip Plant for Beverage Production 109
and high content of biologically active compounds (Dzyuba et al., 2018; Kochubei­Lytvynenko et al., 2022; Osokina et al., 2018; Salvi & Katewa, 2016; Stabnikova et al., 2021, 2024). Although manufacturers of plant- based food products, especially wild ones, face logistical challenges, state support and proper marketing strategies can con­tribute to increased cultivation and consumption volumes (Dunn et al., 2018; Kalchenko et al., 2018; Trusova et al., 2020).
A signicant number of potentially benecial wild plants are widely distributed and have high resistance to variable climatic factors, ensuring their sustainable use. Of particular interest is the cosmopolitan family Lamiaceae, as it has a large concen­tration of species in different zones, such as subtropical, temperate, and even cold regions. Lamiaceae is one of the most important families containing volatile oils and was previously called Labiatae, or the mint family. It comprises 7136 species in 236 genera. This is the largest family in the Lamiales order and includes genera such as Salvia (959 species), Hyptis (292 species), Clorodendrum (327 species), Thymus (318 species), Scutellaria (461 species), Plectratus (406 species), Stachys (374 species) (Trivellini et al., 2016), and Nepeta (295 species) (POWO, 2024). Many cultivated and wild representatives of the Lamiaceae family are used on an industrial level, as they are of great importance for pharmacy, perfumery, cosmetology, and culinary purposes. Additionally, plants of this family are a source of valuable biologically active substances and are used to create functional food products, which can be benecial for preventing hidden hunger (Hutsol et al., 2023).
4.2 NEPETA GENUS PLANTS AS A SOURCE OF VALUABLE PHYTONUTRIENTS
4.2.1 General Information
The genus Nepeta belongs to one of the largest plant families, Lamiaceae, and is part of the subfamily Nepetoideae and the tribe Mentheae. Accorting to Plants of the World Online, it comprises 295 species of herbaceous plants, which are mostly perennial, occasionally annual (POWO, 2024). Many of these species (commonly referred to as catnip or catmint) are native to Europe, with exceptions in Scandinavian countries, the United Kingdom, Germany, Denmark, Belgium, and the Netherlands, where they have been naturalized.
However, the greatest diversity and species richness within the genus are found in two regions: Southwest Asia, where there are 79 species and approximately 60% endemism, and in the western Himalayas, including the adjacent Hindu Kush (Dirmenci et al., 2023). In Southwest Asia, the highest number of endemic species and plant diver­sity of the Nepeta genus is found in Iran and Turkey (Selvi et al., 2022). Nepeta plants are also widespread in the Middle East, Central, and South Asia, and some regions of Africa (Formisano et al., 2011). In America, Nepeta species are naturalized in the United States, Colombia, and Argentina.
110 Wild Edible Plants
At least four species of the genus Nepeta L. grow in Ukraine: N. cataria L.,
N. ucranica L. (N. ucranica subsp. ucranica and N. parviora M. Bieb.), N. grandiora
M. Bieb., and Nepeta nuda L. (N. nuda subsp. nuda) (POWO, 2024).
All plants of the genus Nepeta are characterized by a pleasant aroma, often rem­iniscent of mint and lemon, and are valued as essential oil crops. These plants are well known for their repellent properties and as attractants for cats (Gomes et al., 2020). For use in the perfumery- cosmetic, pharmaceutical, and food industries, certain species of Nepeta L. are cultivated, researched, and their prospective varieties are being developed. Catnip has wide applications in the food industry as a natural avoring and additive, introducing a refreshing aroma and taste to various food products. It is traditionally used as a seasoning for meat dishes and as a component of cheeses (Sargsyan, 2023), with studies exploring the possibilities of enriching bread and our (Kostetska et al., 2023; Osokina et al., 2017), and yogurts (Reihaneh et al., 2018). However, the diversity of species, the specicity of chemical composition, and the high biological activity of plants in this genus may reveal new perspectives for their use in various industries.
4.2.2 Chemical Composition of Catnip and its
Dependence on Genotype and Climatic Factors
The chemical composition of various Nepeta species has been studied since 1955 (Formisano et al., 2011). Although the species N. cataria L. is considered the most studied, research on the chemical composition of different species of the Nepeta genus emerges annually. Primarily, the content and composition of valuable essential oil are studied.
Baranauskienė et al. (2019) studied the essential oils from N. cataria var. citriodora, N. transcaucasica, N. melissifolia, N. sibirica, and N. nuda. They showed that the yield of essential oil varies widely depending on the species of catnip, ranging from
0.08% (N. nuda) to 0.59% (N. cataria). Signicantly higher essential oil content was observed for wild plants from Morocco, 1.02% (Zenasni et al., 2008). This variability is associated with genotype traits and climatic factors (Ivanova et al., 2021). Additionally, the mass fraction of essential oil increases during development, starting from the vege­tative growth phase, reaching its maximum during full owering, and decreasing at the end of owering (Frolova et al., 2019).
The essential oil of the Nepeta genus is characterized by the presence of terpenes (mono- , sesqui- , di- , and triterpenes) (Figure 4.1).
Many researchers have shown that the essential oil and various extracts isolated from N. cataria are rich sources of nepetalactones (iridoid monoterpenes) and other iridoids, which are primarily responsible for various biological activities of the plant, such as attracting cats, insecticidal, and repellent properties, among others (Lichman et al., 2020; Reichert et al., 2019; Yang et al., 2020). Analysis of N. cataria L. essential oil showed that 4a- α,7- α,7a- β- nepetalactone (55– 58%) and 4a- α,7- α,7a- α- nepetalactone (30– 31.2%) are the main components of the essential oil at all stages of plant develop­ment (Zomorodian et al., 2012). Zenasni et al. (2008) demonstrate even higher nepetalactone content: more than 70% of oils from N. atlantica, N. tuberosa, N. cataria, and 39.4% of oils from N. granatensis. According to other authors, N. cataria contains
The Catnip Plant for Beverage Production 111
FIGURE 4.1 Composition of Nepeta essential oil.
over 80% nepetalactones (Azizian et al., 2021; Baranauskienė et al., 2019; Tiwari et al., 2023). However, Mollova et al. (2023) claim that the amount of nepetalactones in the studied N. cataria essential oil was decient and explain these differences by the method of obtaining the essential oils. Not all essential oils from Nepeta species contain nepetalactones in their composition. Depending on the composition of the main compounds in the essential oils, Nepeta species are divided into two groups: one contains various isomers of nepetalactone, and the other contains compounds different from nepetalactone isomers, such as 1,8- cineole, β- caryophyllene, caryophyllene oxide, β- farnesene, α- citral, β- citronellol, and others, which are the main components (Sharma & Cannoo, 2013). The main compound of species that do not contain nepetalactone is 1,8- cineole, and it is present in N. heliotropifolia. On the other hand, caryophyllene oxide was the main compound in the essential oil of N. cilicia, N. betonicifolia, and N. nuda ssp. nuda, while α- pinene was present in the oil of N. glomerulosa, and caryophyllene oxide in the oil of N. ssa (Hussain et al., 2015). Nevertheless, the composition of essen­tial oil is strongly dependent not only on the species, but also on the soil and climatic factors. This is well illustrated by comparing the qualitative composition of the essential oil of N. cataria from different regions. Signicant differences are observed in the presence of major terpenoids and other aroma- forming compounds (Table 4.1).
The most signicant biological activity in aromatic plants in general, and in catnip in particular, is attributed to phenolic compounds, which are secondary metabolites represented by substances from the group of avonoids (rutin, luteolin, cynaroside, hyperoside, quercetin, and apigenin), hydroxycinnamic acids (caffeic, chlorogenic, and rosmarinic acids), and phenolic carboxylic acids (gallic and vanillic acids).
It is known that the total content of phenolic compounds and avonoids signi­cantly varies depending on the plant species and their geographical origin. Additionally, different research groups often use different methods for extraction and assessing the content of phenolic compounds, making these data difcult to compare. However, there are several studies aimed on the different Nepeta species comparison. According to the results of Azizian et al. (2021), the highest total content of phenolic compounds was found in N. cataria (87.40 g gallic acid equivalents (GAE)/ kg of dry weight (DW)), followed by N. racemosa, N. congesta, and N. saccharata (24.59 g GAE/ kg DW). N. cataria also exhibited the highest total avonoid content (1.99 g quercetin quivalents (QE)/ kg DW), followed by N. saccharata, N. congesta, and N. racemosa. Six species of Nepeta (N. cataria, N. racemosa, N. sibirica, N. nuda, N. melissifolia, and N. grandiora)
newgenrtpdf
TABLE 4.1 Key volatile compounds of Nepeta cataria essential oil
SOURCE, REFERENCE
COMPOUND
BULGARIA, (MOLLOVA ET AL.,
2023)
CHINA, (YANG ET AL.,
2020)
EGYPT, (IBRAHIM ET AL.,
2017)
GERMANY, (SUSCHKE ET AL.,
2007)
INDIA, (JOSHI ET AL.,
2021)
MOROCCO, (ZENASNI ET AL.,
2008)
KOREA, (KIM ET AL.,
2006)
PAKISTAN, (GILANI ET AL.,
2009)
SERBIA, (VUKOVIC ET AL.,
2016)
TURKEY, (ADIGUZEL ET AL.,
2009)
Monoterpenes:
Nepetalactone (unspecified) - - + - - - + - - ­4a- α,7- α,7a- β- Nepetalactone + + - + - + - - - + 4a- α,7- α,7a- α- Nepetalactone - - - + + - - - + + 4a- α,7- β,7a- α- Nepetalactone + + - - - - - - - + 4a- β,7- α,7a- β- Nepetalactone - - - + - - - - - - Dihydronepetalactone - - - + - + - - - ­Dehydronepetalactone - - - - + - - - - -
α- Pinene + - + + + + - + + - β- Pinene + - - + - + + + + +
Terpinene - - - - - + - - - -
α- Terpinene - - - - - - - + - - γ- Terpinene - - - - - - + - + -
Camphene - - - - - + - - - ­Limonene + + + - - + - - - + Sabinene + - + + - + - - - ­(E)- Sabinene - - - - - - + - - ­Myrcene + - - - - - - - - + β- Myrcene - - - - - - + - - ­allo- Ocimene + - - - - - - - - - (E)- β- Ocimene + - - + - - - + + -
112 Wild Edible Plants
(Z)- β- Ocimene + - + + - - - + - - (E)- α- Bergamoten - - - - - - - + - - Terpinolene - - - - - - - + - -
α- Terpinolene - - - - - - - - + ­α- Phellandrene - - - - - + - + - ­ρ- Cymene + - - - + + - - + - δ- 3- Carene - - - - - - + - - -
Sesquiterpenes and Sesquiterpenoids:
β- Bourbonene - - - - - - - + - - β- Caryophyllene + - + + + + + + + + α- Curcumene - - - - - + - - - -
Germacrene D + - - - - - + + + ­β- Bisabolene - - - - - - - - + ­(Z)- α- Bisabolene - - - - - - - + - ­Bicyclogermacrene - - - - - - - - + ­Bicycloelemene - - - - - - - - + ­Aromadendrene - - - - - - - - + ­Viridiflorol + - - - - - - - + ­(E)- β- Farnesene - - - + - - + + - ­(Z)- β- Farnesene + - - - - - - - - -
δ- Cadinene - - - - - - - + + ­α- Bisabololoxide B - - - - - - - - + ­α- Bisabolone oxide A - - - - - - - - + ­α- Caryophyllene + - - + - - - - - - α- Copaene - - - - - - - + + -
(continued)
The Catnip Plant for Beverage Production 113
newgenrtpdf
TABLE 4.1 (Continued)
SOURCE, REFERENCE
COMPOUND
BULGARIA, (MOLLOVA ET AL.,
2023)
CHINA, (YANG ET AL.,
2020)
EGYPT, (IBRAHIM ET AL.,
2017)
GERMANY, (SUSCHKE ET AL.,
2007)
INDIA, (JOSHI ET AL.,
2021)
MOROCCO, (ZENASNI ET AL.,
2008)
KOREA, (KIM ET AL.,
2006)
PAKISTAN, (GILANI ET AL.,
2009)
SERBIA, (VUKOVIC ET AL.,
2016)
TURKEY, (ADIGUZEL ET AL.,
2009)
α- Fenchene - - - - - - - + - - α- Humulene - - + - + - + + + - α- Thujene - - - - - - + - - -
Pregeijerene - - - - - - - - + -
Monoterpene Aldehydes and Ketones:
Citral - - - - - - + - - ­Neral (citral b) + - + + - - - - - ­Geranial (citral a) + - + + - - - - - ­Citronellal + - + - - - - - - ­Bergamal + - - - - - - - - ­Pulegone - - - - - + - - + + Menthone - - - - - + - - - ­(E)- Menthone - - - - - - - - + ­Isomenthone - - - - - - - - + ­Verbenone - - + - - - - - - ­Camphor - + - - - - - - - + Carvone - - - - - - - - + ­Pinocarvone - - - - - - - - - + Piperitone - - - - - - - - - +
114 Wild Edible Plants
Piperitenone - - - - - - - - - + Pinocamphone - - - - - - - - - + Isopulegol + - - - - - + - - ­Thujone - - - - - + - - - -
Monoterpenol Esters:
Bornyl acetate - - - - - - - + - ­Citronellyl acetate + - - - - - - - - ­Geranyl acetate - - - - - - - + - ­Linalyl acetate - - - - - + - - - ­Terpinene- 4- acetate - - - - - - - + - ­Neryl acetate + - - - - - - - - -
Mono- , Diterpene Hydroxides:
Citronellol + - + - - + - - - ­Menthol - - - - - + - - + ­1,8- Cineol (Eucalyptol) + + - - - + + + - + Linalool - + + + - - - + + ­L- Linalool - - - - - - + - - ­β- linalool + - - - - - - - - - 6- Methyl- 5- hepten- 2- ol - - - - - - - - + ­Terpinen- 4- ol - - - - + - - + - + 3- Cyclohexen- 1- ol - - - - - - + - - ­3- Hexen- 1- ol - - - - - - + - + ­Geraniol + - + - - - - - - ­(E)- Geraniol - - - - - - - + - ­Neodihydrocarveol - - - - + - - - - -
The Catnip Plant for Beverage Production 115
(continued)