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24
372
L. Wolford
. Fig. 24.11 A low-grade ReA may actually cause bone deposition
around the condyle and fossa (white arrows), with slow destruction of the articular disc (green arrow). ReA that stimulates bone deposi­tion can result in bony ankylosis
resorption; and articular disc may be in position but surrounded by a pannus (reactive tissue) that eventually destroys the disc but also is the cause of condylar and articular eminence resorption (. Fig. 24.12). In more severe cases, particularly in JIA patients, the condylar stump may function forward beneath the remaining articular eminence.
fascia and muscle aps, dermal grafts, rib grafts, sterno­clavicular grafts, and vertical sliding ramus osteotomy. However, the disease process that created the original TMJ pathology can attack the autogenous tissues used in the TMJ reconstruction causing failure of the grafts. Performing orthognathic surgery only for MMA with or without CCWR will have a high failure rate relative to skeletal and occlusal stability, pain, and maintenance of the oropharyngeal airway.

24.5 Trauma

Traumatic injuries to the mandible may create facial deformities leading to OSA, particularly involving untreated displaced bilateral or unilateral subcondy­lar fractures. Patients may present with: (1) mandible retruded with deviation toward the affected side if unilateral; (2) pain and jaw dysfunction; (3) decient growth on the affected side(s) in growing patients; (4) Class II skeletal and occlusal relationships with ante­rior open bite; and (5) unilateral cases, premature con­tact of the posterior occlusion on the affected side with anterior and contralateral open bite. Imaging features could include the following: (1) evidence of subcondylar fractures; (2) condyles malpositioned downward, for­ward, and medial to the fossa; and (3) decreased vertical ramus/condyle length.
MRI will also show the disc position and condition. The disc may be displaced with the condyle, or the disc can remain in the fossa with only the condyle displaced (.
Fig.24.13).
24.4.1 Implications fortheOSA Patient
The most predictable treatment for OSA patients with the TMJs affected by CT/AI diseases includes the fol­lowing: (1) bilateral reconstruction of the TMJs and CCWR and advancement of the mandible with custom­tted total joint prostheses (. Fig. 24.8); (2) coro­noidectomies if the ramus is signicantly advanced or vertically lengthened with the prostheses; (3) autog­enous fat graft harvested form the abdomen or buttock, packed around the prosthesis in the articulation area [7679]; (4) maxillary osteotomies for advancement with CCWR; and (5) additional adjunctive procedures indi­cated (i.e., genioplasty, rhinoplasty, turbinectomies, and septoplasty) [8, 3459]. Other techniques that have been advocated for TMJ reconstruction for this patient popu­lation include using autogenous tissues such as temporal
24.5.1 Implications fortheOSA Patient
At the initial presentation of the trauma, the options for treating subcondylar fractures are open reduction, closed reduction, or no treatment. The amount of dis­placement and the condition of the fracture(s) will dic­tate the necessary treatment to x the problem. When identied early, fractures may be best treated by open reduction for signicantly displaced segments or closed reduction for minimally displaced segments to achieve a symmetric face and stable occlusion. If the condyle is minimally to moderately displaced, still salvageable along with its articular disc but already healed, then it is possible that orthognathic surgery could realign the jaw structures properly, and if the disc is displaced, it can be repositioned with a Mitek anchor (.
Fig.24.2) [2433].
MRI Evaluation forPatients withTMJ Disorders andObstructive Sleep Apnea
373
24
a
c
b
. Fig. 24.12 a Sagittal view of the joint with JIA. There is signi-
cant loss of the vertical height of the condyle and commonly “mush­rooming” (increased AP dimension of the residual condyle). The articular disc is commonly in position but surrounded by a reactive pannus (thin gray tissue surrounding the disc). b This is the same image but with the mushroomed condylar head and disc outlined.
The gray tissue surrounding the disc is responsible for destruction of the joint. Notice also that the articular eminence has signicantly resorbed as well. c Coronal views show the signicant condylar resorption and transverse narrowness of the residual condylar ele­ments classic with JIA
24
ab
374
L. Wolford
. Fig. 24.13 a Sagittal view of a left mandibular subcondylar frac-
ture with the condyle displaced anteromedial to the ramus. The artic­ular disc (green arrows) is anteriorly displaced relative to the fossa but posteriorly displaced relative to the condylar head. C condyle, E
If the condyle is severely deformed and nonsalvageable, then the most predictable method for reconstruction of the TMJ is using custom-tted total joint prosthe­ses (. Fig.24.8) [8, 3459], TMJ fat grafts [7679], and repositioning of the mandible, if there is an associated mandibular malalignment. Other treatment options for TMJ reconstruction following removal of the displaced condyles are rib grafts, sternoclavicular grafts, vertical ramus osteotomies, etc., but these outcomes are far less predictable.
OSA patients that have subcondylar fractures with malunion and malalignment and a retruded mandible will have the best outcome predictability with TMJ reconstruction and mandibular advancement with custom- tted total joint prostheses and MMA with CCWR if also indicated.
articular eminence, F fossa. b Coronal view illustrates the medial dis­placement of the condylar head c. The disc (green arrows) is laterally displaced relative to the condylar head
radiographic characteristics of TMJ ankylosis, particu­larly when occurring in children, include the following: (1) decreased jaw mobility and function; (2) decreased growth on the involved side(s); (3) retruded mandible; (4) facial asymmetry if unilateral involvement with the mandible shifted toward the ipsilateral side; (5) Class II occlusion; (6) radiographic evidence of heterotopic bone around the TMJ(s); (7) decreased vertical height of the ramus and posterior maxilla; and (8) decreased oropharyngeal airway [80].
MRI may demonstrate evidence of brous or bony
ankylosis between the condyle and the fossa or hetero­topic bone surrounding the joint (. Fig.24.14) appear­ing as a dense black mass. In the early stages of the process, the disc may be identiable with or without dis­placement and there may be evidence of inammation particularly when the etiology is related to an inam­matory or infectious process. Areas of calcication and

24.6 TMJ Ankylosis

osteophytes may be seen. As the disease progressed, the disc and joint space may not be visualized.
TMJ bony ankylosis can occur bilateral or unilateral, usually develops as a result of trauma, inammation, sepsis, and/or systemic diseases, resulting in severely lim-
24.6.1 Implications fortheOSA Patient
ited jaw function as well as oral hygiene and nutritional problems. When this condition occurs during the growing years, it can severely affect jaw growth and development as well as contribute to OSA.In unilateral ankylosis, the other condyle will continue to grow but may be retarded in its true growth potential. The common clinical and
The most predictable treatment for the OSA patient with ankylosis includes the following: (1) release of the ankylosed joint, condylectomy, removal of the hetero­topic and reactive bone with thorough debridement of the TMJ and adjacent areas; (2) coronoidectomies if the
MRI Evaluation forPatients withTMJ Disorders andObstructive Sleep Apnea
375
24
a
c
b
. Fig. 24.14 a MRI sagittal view of TMJ ankylosis. “C” identies
the condylar head. The bony mass outlined by the green arrows sur­rounds the condyle. AC auditory canal. b Coronal view shows bony continuity of the condyle and fossa. c Sagittal view of another case
ramus is signicantly advanced or vertically lengthened with the prosthesis, or if coronoid hyperplasia developed which is a risk, particularly with ankylosis at an early age; (3) reconstruct the TMJs and advance the mandible with a custom-tted total joint prosthesis (. Fig.24.8); (4) autogenous fat graft (harvested from the abdomen or buttock) packed around the prosthesis in the TMJ articulation area; (5) maxillary osteotomies for MMA with CCWR; and (6) adjunctive procedures indicated
with a large dense bony mass surrounding the condyle associated with ankylosing spondylitis. The condyle is not identiable. AC audi­tory canal
such as genioplasty, turbinectomies, nasoseptoplasty, and rhinoplasty [8083].
Other techniques that have been advocated for reconstruction of TMJ ankylosis include using autog­enous tissues such as temporal fascia and muscle aps, dermis- fat grafts, rib grafts, sternoclavicular grafts, ver­tical sliding osteotomy, and gap arthroplasty. The total joint prosthesis with a fat graft packed around it is a superior technique.
376
L. Wolford
24

24.7 Other End-Stage TMJ Conditions

Other TMJ end-stage conditions that can contribute to OSA include (1) congenital deformities (i.e., hemifacial microsomia, Treacher-Collins syndrome); (2) multiply operated joints; (3) failed TMJ alloplastic implants; and (4) failed autogenous tissue used for TMJ reconstruction.
MRI evaluation of these conditions may not be par­ticularly helpful for diagnosis and treatment planning as signicant distortion and interference may render the MRI unreadable and nondiagnostic. CBCT and CT scans would be the imaging of choice for initial evalua­tion of these conditions.
OSA patients with these TMJ pathologies may benet from TMJ reconstruction and mandibular advancement with custom-tted total joint prosthesis (. Fig. 24.8), placement of fat grafts around the articulating part of the prostheses, as well as concomitant maxillary oste­otomies for MMA with CCWR, and other indicated adjunctive procedures to achieve the best outcome results relative to function, stability, esthetics, and elimi­nation of pain.
Studies show good outcomes with these treatment protocols. However, the quality of results decreases as the number of previous TMJ surgeries increases, partic­ularly in reference to pain relief and jaw function. When the TMJ concepts total joint prostheses system is used as the rst or second TMJ surgery, the success rate is very good relative to jaw function, stability, facial bal­ance, and pain relief. After two or more previous TMJ surgeries, the decrease or elimination of pain and jaw function is far less predictable [8, 3459, 7687].

24.8 Summary

Healthy and stable TMJs are necessary for quality treat­ment outcomes in orthognathic surgery for the OSA patients. If TMJ pathology is preexisting, orthognathic surgery results may be unsatisfactory relative to func­tion, esthetics, skeletal, and occlusal stability as well as pain. The oral and maxillofacial surgeon should be sus­picious of possible TMJ problems in the OSA patient with the following conditions: (1) Class II high occlusal plane angle facial morphology with retruded mandible; (2) progressively worsening Class II occlusal and jaw relationship; (3) facial asymmetry, particularly with pro­gressive worsening; (4) anterior open bite and/or lateral open bite; (5) patients reporting headaches, TMJ pain, myofascial pain, history of clicking and popping of the TMJs, and/or ear symptoms; and (6) history of CT/AI diseases, other joint problems, facial trauma, etc. The surgeon should not ignore these symptoms. With one or more of these symptoms, OSA patients should be evalu­ated for possible TMJ pathology. An MRI of the TMJs
can aid in the identication of the specic TMJ pathol­ogy and progression of the disease process and indicate the surgical procedures necessary to maximize the treat­ment outcomes. Failure to recognize and treat these con­ditions can result in signicant relapse, increased pain, decrease of the oropharyngeal airway, and a greater complexity of subsequent treatment.
During the past three decades, major advancements have been made in TMJ diagnostics and the develop­ment of surgical procedures to treat and rehabilitate the pathological, dysfunctional, and painful TMJ.Research has clearly demonstrated that TMJ and orthognathic surgery can be safely and predictably performed at the same operation, but it does necessitate the correct diag­nosis and treatment plan, as well as requires the sur­geon to have expertise in both TMJ and orthognathic surgery. The surgical procedures can be separated into two or more surgical stages, but the TMJ surgery should be done rst. With the correct diagnosis and treat­ment plan, combined TMJ and orthognathic surgical approaches provide complete and comprehensive man­agement of OSA patients with coexisting TMJ pathol­ogy and dentofacial deformities.

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Maxillary Surgical Procedures forCorrection ofObstructive Sleep Apnea
WillR.Allen andMattJ.Madsen
Contents
25.1 Background – 382
25.2 Treatment Planning Maxillary Surgery – 382
25.2.1 Bone Anatomy – 383
25.2.2 Vascular Anatomy – 383
25.3 Lefort IOsteotomy Including Modications – 384
25
25.4 Surgically Assisted Rapid Palatal Expansion (SARPE) – 388
25.5 Adjunct Procedures – 389
25.6 Complications – 390
References – 391
© Springer Nature Switzerland AG 2021 K. B. Kim et al. (eds.), Management of Obstructive Sleep Apnea, https://doi.org/10.1007/978-3-030-54146-0_25
382
W. R. Allen and M. J. Madsen
25

25.1 Background

Obstructive sleep apnea (OSA) is a sleep disorder that affects approximately 5–15% of the adult general popu­lation [1]. It is characterized by repetitive intermittent complete or partial breathing obstruction during sleep due to collapse of the airway. This interrupted respira­tion affects sleep pattern due to continuous arousals which often leads to daytime sleepiness and contribute to a host of medical comorbidities. These obstructions lead to decreased oxygen saturation and increased par­tial pressure of blood CO2 levels. This affects patient well-being and has been documented to be associated with a host of medical comorbidities including hyper­tension [26], cardiovascular disease [4], heart failure [46] metabolic syndrome [3, 4, 6], and stroke [5, 6].
Obstructive sleep apnea is commonly observed in patients with obesity [6], large neck circumference, male sex, maxillary or mandibular deciency [7, 8], long upper airway length [813], narrow nasal passage [14], maxillary constriction [14], and a narrow pharynx [15]. A more detailed discussion of the anatomy, physical ndings, and diagnosis is described in detail elsewhere in this text.
First-line treatment for OSA is nonsurgical medical management with continuous positive airway pressure (CPAP). This treatment modality is poorly tolerated by some patients which necessitates other avenues includ­ing surgical intervention. Patients with a Respiratory Disturbance Index (RDI) of greater than 20 episodes per hour, oxygen saturation less than 90%, hypertension, arrhythmia, anatomical abnormalities of the upper air­way, or failure of medical management are candidates for surgical intervention.
Surgical management has traditionally been divided into two phases. Phase 1 focuses on correction of aber­rant nasal, palatal, tongue, and septum anatomy. Therapy includes nasal septoplasty, turbinectomy, tongue advancement, palate reduction including UPPP, and hyoid myotomy. Phase 2 therapy includes skeletal correction, most often in the form of maxillomandibu­lar advancement.
For patients with failed surgical intervention via phase 1 therapies or nonsurgical therapy, maxilloman­dibular advancement (MMA) often with counterclock­wise rotation of the mandible has become the surgery of choice. This surgery consists of advancing the maxilla with a LeFort I osteotomy and the mandible with a bilateral sagittal split osteotomy of the mandible (BSSO) as much as 10 millimeters. Often, surgical correction involves rotating the occlusal plane in a counterclock­wise (CCW) fashion. MMA results in a decrease in lat­eral pharyngeal wall tension, which is a determinate factor in increasing the airway size which improves a patient’s apnea hypopnea index (AHI) [1618], O
satu-
2
ration [16, 18], and ESS score [1618] following CCW advancement. This CCW rotation has been shown to improve OSA in patients by reducing the apnea hypop­nea index (AHI) [7, 12, 1724], improve Epworth Sleepiness Scale [16, 17, 20, 21], improve oxygen satura­tion [7, 16, 19], increase airway diameter [11, 12, 15, 20,
2528], decrease airway length [11, 12] which improves
clinical symptoms and overall quality of life.
Traditional approaches have focused on bimaxillary surgery or single mandibular surgery, specically man­dibular advancement to improve retrolingual airway space. However, recent studies have sought to under­stand the role of improving OSA via maxillary orthog­nathic surgery procedures. Orthopedic procedures such as rapid maxillary expansion (RME) [2935] in children and surgical assisted rapid palatal expansion (SARPE) [14, 3639] or segmental Lefort surgery in adults dem­onstrate improvements in OSA. The mechanism by which AHI is improved is likely due to widening of the nasal oor which widens the nasal cavity [29, 30, 33]. This decreases the nasal resistance to airow reducing obligate mouth breathing which has been shown to be a contributing factor to abnormal dentofacial develop­ment [40]. Additionally, a pathologically constricted maxillary arch does not allow for a normal tongue pos­ture contributing to a posterior and inferior tongue position [41]. Normalizing maxillary arch width and increasing the horizontal dimension of the dentoalveo­lar framework, allows the tongue enough space within the dentoalveolar process. This new tongue posture improves pharyngeal airway [35] and even improves the airway dimension in the lower airway near the epiglottis [14]. In addition to tongue position, correction and wid­ening of the skeletal landmarks, the surrounding soft tissue anatomy of the airway responds in kind. Maxillary advancement pulls the velum and velopharyngeal mus­cles forward which results in less tension [7, 19, 27].
The greatest perceived benet to maxillomandibular advancement or advancement of the maxilla or mandi­ble in single jaw surgery is to decrease airway resistance. As described in Pouiseuilles’s law, P=8μLQ/πr4 where P is pressure difference at ends of the airway, L=length airway, Q=volume of air which passes per given time, μ= dynamic viscosity, r = airway radius. In short, the resistance of a tube is proportional to the fourth power of its radius. As we surgically increase the radius of the airway, resistance greatly decreases. This chapter will discuss maxillary procedures for the OSA patient.

25.2 Treatment Planning Maxillary Surgery

Prior to surgery, an accurate and comprehensive exami­nation should be performed to determine the patient’s diagnosis. Clinical records for orthognathic surgery con-