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208
Fig. 17.35 The common enterotomy is positioned for closure
Fig. 17.36 The enterotomy is closed using a running 3/0 absorbable suture
H. Takla
Fig. 17.37 Closure of mesenteric defect behind the jejunojejunostomy using 2/0 permanent suture
Fig. 17.38 Completed closure of mesenteric defect
17 Robotic Roux-en-Y Gastric Bypass
Fig. 17.39 Exposure of pseudo-Peterson space
Fig. 17.40 Closure of pseudo-Peterson space using a nonabsorbable suture
209
Fig. 17.41 Endoscopy to inspect the anastomosis
Postoperative Management andInstructions
• In our practice, all of our patients are admitted to the oor for observation for
24h and most are discharged the next morning when they meet the criteria for
discharge.
• We usually obtain a Hematocrit level 4h postoperatively and a complete blood
count (CBC) and basic metabolic panel (BMP) the next morning. This gives a
baseline in case any postoperative bleeding issues are encountered.
• The main monitoring parameters we follow are signs of bleeding, early leaks that
are very uncommon as well as venous thromboembolism (VTE) events. Some of
210
H. Takla
the signs are common between different parameters that include tachycardia,
fever, increasing abdominal pain, peritoneal signs, and metabolic derangements.
One should be diligent in investigating these signs as it may signify an underly-
ing early complication. Failure of normal progression should keep the surgeon
on alert to investigate the underlying etiology.
• We use prophylactic heparin routinely postoperatively unless the patient has a
contraindication or a coagulopathy that would require a different type of deep
venous thrombosis (DVT) prophylaxis.
• We usually start with a water trial in the recovery room once the patient is fully
conscious, and then advance to a noncarbonated, nonconcentrated sweet low-
calorie clear liquid diet in 3–4oz increments.
• The next morning the patient’s diet is advanced further to include protein shakes
in 3–4oz increments, and, if well tolerated, the patient is usually discharged
home within 24h of their procedure.
• We use scheduled Tylenol and IV NSAID for pain control while the patient is
admitted with small narcotic doses as needed for breakthrough pain, which is
infrequently needed.
• The patient is also placed on an oral proton pump inhibitor for 1month postop-
eratively to theoretically reduce hyperacidity and risk marginal ulcers as well as
allowing mucosal healing in the early postoperative period.
• The rst postoperative visit is usually scheduled within 1–2 weeks
postoperatively.

Complications

Early Complications
An anastomotic leak from the gastrojejunal anastomosis is a potentially fatal complication. It typically manifests within 24h in a gastric bypass; however, it could manifest later. We quote our patients 0.5–1% risk in our practice, espe­cially with the different intraoperative checks, including leak test using ICG, upper endoscopy, and checking blood supply at the anastomosis using ICG as well.
Hemorrhage from anastomoses and staple lines has a high chance of resolving spontaneously, but may require transfusion while awaiting resolution.
Bowel obstruction can occur early or late, the former due to Roux-en-O error, where the closed-loop obstruction is created by misidentication of Roux and BP limbs. Early bowel obstruction can also be due to iatrogenic stricture at the jejuno­jejunal anastomosis either due to a kink as the Roux limb enters the anastomosis or due to intraluminal bleeding, port site hernia, and small bowel volvulus. Early inter­nal hernias are very uncommon. If any of these issues are identied, prompt surgical intervention is necessary to avoid further complications and avoid precipitation of a Gastrojejunal anastomotic leak.
17 Robotic Roux-en-Y Gastric Bypass
211
Deep vein thrombosis or pulmonary embolism can be fatal after bariatric sur­gery, and so prevention is critical, with intermittent calf pumps intraoperatively, compression stockings, and postoperatively chemical prophylaxis.
Late Complications
Internal herniation can occur in gastric bypass in one of three ways. Peterson’s her­nia can occur following herniation of bowel through the defect created between the jejunal mesentery of the alimentary limb and the transverse mesocolon. The other two hernias can occur at the mesenteric defect created by the jejunojejunostomy (JJ) anastomosis and through the mesocolic defect if the Roux limb passes retrocolic. As weight is lost, the bowel anatomy changes and mesenteric defects can become accentuated or created. The presentation is often subacute, with postprandial pain or bloating; however, acute presentations with strangulation can also occur. Diagnostic laparoscopy is the investigation of choice, with a reduction of the hernia and closure of the mesenteric defect [13, 14].
Stricture at the gastrojejunal anastomosis can occur in up to 5% of patients. Contributing factors include excess tension, ischemia and technical aspects of meth­ods used to create the anastomosis [15, 16].
Micronutrient deciency can occur, and lifelong vitamin/mineral supplementa­tion is essential for preventing these decits caused by the loss of absorption at the duodenojejunal region of the bowel. Common deciencies include thiamine, vita­min B12, folate, iron, zinc, and vitamin D.
Dumping syndrome can present as postprandial malaise precipitated by the rapid passage of food into the anastomosed jejunum at the GJ anastomosis. Management is typically conservative with advice on altering diet and decreasing the size of meals.
Outcomes andConclusion
• Roux-en-Y gastric bypass has been standard in metabolic and bariatric surgery
for several decades, and the outcomes and safety prole are well known and
beyond the context of this chapter.
• Patients who undergo RGYB are typically reported to experience approximately
60–70% excess body weight loss, with over 75% control of comorbidities. In a
study published in NEJM looking at 12-year weight and metabolic outcomes
after gastric bypass, the adjusted mean change from baseline body weight in the
surgical group was −45.0kg, 36.3kg, and35.0kg at 2, 6, and 12years, while
that in the two nonsurgical groups (1: no surgery due to insurance reasons; 2: did
not seek surgery) at 12years was 2.9kg and 0.0 kg, respectively. Similarly,
higher rates of remission in the surgical group when evaluating preoperative
comorbidities such as type 2 diabetes (51% at 12 years), hypertension, and
hyperlipidemia [17].
212
H. Takla
• Roux-en-Y gastric bypass (RYGB) demonstrates high rates of type 2 diabetes
mellitus (T2DM) remission, a phenomenon hypothesized to be mediated mainly
by weight loss. Compared to procedures that do not bypass the proximal small
intestines, such as sleeve gastrectomy (SG), RYGB exhibits weight-loss-
independent intestinal mechanisms conducive to T2DM remission. In a retro-
spective review, Ghanem etal. showed that T2DM remission rates after RYGB
are maintained despite weight recurrence, arguing for a concurrent weight-loss-
independent metabolic benet likely facilitated by bypassing the proximal small
intestine [18].
• Furthermore, it was shown in a retrospective cohort review that patients with a
recent history of T2DM who undergo early RYGB experience signicantly
higher and earlier T2DM remission compared to patients with a prolonged his-
tory of preoperative T2DM, suggesting potential benet of early surgical inter-
vention to manage patients with obesity and T2DM [19].
• It is, however, important to mention and explore if the shift in paradigm toward
robotic bariatric surgery has contributed to improved surgical outcomes for these
procedures.
• There are several studies as mentioned in the introduction that looked at this, and
so far it has been demonstrated that the outcomes are comparable to the laparo-
scopic approach, especially after the surgeon moves past their learning curve.
• It is arguable that with the advanced ergonomics, superior visual tools, and
wristed instruments, the robotic platform is superior in its offerings to the sur-
geon and enables a wider variety of surgeons with variable skill set to adopt MIS
surgery, especially in the eld of bariatric surgery.
• The gastric bypass is a technically demanding operation with a variety of steps
that require superior technical skills and can be challenging for trainees and
young surgeons. In our experience, the robotic platform allows easier adoption
and teaching of these technically challenging steps.
• In addition, the marked increase in market share for robotic bariatric surgery is a
sign that the technology is here to stay and is well sought by surgeons as well as
patients.

References

1. Wittgrove AC, Clark GW, Tremblay LJ.Laparoscopic gastric bypass, Roux-en-Y: preliminary report of ve cases. Obes Surg Incl Laparosc Allied Care. 1994;4(4):353–7.
2. Beckmann JH, Bernsmeier A, Kersebaum J-N, etal. The impact of robotics in learning Roux­en- Y gastric bypass: a retrospective analysis of 214 laparoscopic and robotic procedures. Obes Surg. 2020;30:2403.
3. Bindal V, Bhatia P, Dudeja U, Kalhan S, Khetan M, John S, Wadhera S.Review of contempo­rary role of robotics in bariatric surgery. J Minim Access Surg. 2015;11(1):16–21. https://doi.
org/10.4103/0972- 9941.147673. PMID: 25598594; PMCID: PMC4290112.
4. Park CW, Torquati A. Physiology of weight loss surgery. Surg Clin North Am. 2011;91(6):1149–61, vii.
5. Peterli R, Wölnerhanssen B, Peters T, Devaux N, Kern B, Christoffel-Courtin C, Drewe J, von Flüe M, Beglinger C.Improvement in glucose metabolism after bariatric surgery: comparison
17 Robotic Roux-en-Y Gastric Bypass
of laparoscopic Roux-en-Y gastric bypass and laparoscopic sleeve gastrectomy: a prospective randomized trial. Ann Surg. 2009;250(2):234–41.
6. Aminian A.Bariatric procedure selection in patients with type 2 diabetes: choice between Roux-en-Y gastric bypass or sleeve gastrectomy. Surg Obes Relat Dis. 2020;16(2):332–9.
https://doi.org/10.1016/j.soard.2019.11.013. Epub 2019 Dec 2
7. Wallenius V, Alaraj A, Björnfot N, Orrenius B, Kylebäck A, Björklund P, Werling M, Thorell A, Fändriks L, Maleckas A.Sleeve gastrectomy and Roux-en-Y gastric bypass in the treatment of type 2 diabetes. Two-year results from a Swedish multicenter randomized controlled trial. Surg Obes Relat Dis. 2020;16(8):1035–44. https://doi.org/10.1016/j.soard.2020.04.033. Epub 2020 May 5
8. Salminen P, Helmiö M, Ovaska J, Juuti A, Leivonen M, Peromaa-Haavisto P, Hurme S, Soinio M, Nuutila P, Victorzon M.Effect of laparoscopic sleeve gastrectomy vs laparoscopic Roux-en-Y gastric bypass on weight loss at 5 years among patients with morbid obesity: The SLEEVEPASS Randomized Clinical Trial. JAMA. 2018;319(3):241–54. https://doi.
org/10.1001/jama.2017.20313. PMID: 29340676; PMCID: PMC5833550.
9. Angeles PC, Robertsen I, Seeberg LT, Krogstad V, Skattebu J, Sandbu R, Åsberg A, Hjelmesaeth J.The inuence of bariatric surgery on oral drug bioavailability in patients with obesity: a sys­tematic review. Obes Rev. 2019;20(9):1299–311.
10. O’Brien PE. Bariatric surgery: mechanisms, indications and outcomes. J Gastroenterol Hepatol. 2010;25(8):1358–65.
11. Jamal MK, DeMaria EJ, Johnson JM, Carmody BJ, Wolfe LG, Kellum JM, Meador JG. Insurance-mandated preoperative dietary counseling does not improve outcome and increases dropout rates in patients considering gastric bypass surgery for morbid obesity. Surg Obes Relat Dis. 2006;2(2):122–7. https://doi.org/10.1016/j.soard.2006.01.009.
12. Orandi BJ, Purvis JW, Cannon RM, Smith AB, Lewis CE, Terrault NA, Locke JE.Bariatric sur­gery to achieve transplant in end-stage organ disease patients: A systematic review and meta­analysis. Am J Surg. 2020;220(3):566–79. https://doi.org/10.1016/j.amjsurg.2020.04.041. Epub 2020 Jun 13. PMID: 32600846; PMCID: PMC7484004
13. Altieri MS, Carter J, Aminian A, Docimo S Jr, Hinojosa MW, Cheguevara A, Campos GM, Eisenberg D.Clinical Issues Committee of the American Society for Metabolic and Bariatric Surgery. American Society for Metabolic and Bariatric Surgery literature review on preven­tion, diagnosis, and management of internal hernias after Roux-en-Y gastric bypass. Surg Obes Relat Dis. 2023;19(7):763–71. https://doi.org/10.1016/j.soard.2023.03.019. Epub 2023 Apr 8
14. Stenberg E, Ottosson J, Magnuson A, etal. Long-term safety and efcacy of closure of mes­enteric defects in laparoscopic gastric bypass surgery: a randomized clinical trial. JAMA Surg. 2023;158(7):709–17. https://doi.org/10.1001/jamasurg.2023.1042.
15. Carrodeguas L, Szomstein S, Zundel N, Lo Menzo E, Rosenthal R.Gastrojejunal anastomotic strictures following laparoscopic Roux-en-Y gastric bypass surgery: analysis of 1291 patients. Surg Obes Relat Dis. 2006;2:92–7.
16. Gonzalez R, Lin E, Venkatesh KR, Bowers SP, Smith CD.Gastrojejunostomy during laparo­scopic gastric bypass: analysis of 3 techniques. Arch Surg. 2003;138:181–4.
17. Sarabu N. Weight and metabolic outcomes 12 years after gastric bypass. N Engl J Med. 2018;378(1):93–4.
18. Ghanem OM, Abi Mosleh K, Kerbage A, Lu L, Hage K, Abu Dayyeh BK.Continued diabetes remission despite weight recurrence: gastric bypass long-term metabolic benet. J Am Coll Surg. 2024;238:862.
19. Hage K, Abi Mosleh K, Sample JW, Vierkant RA, Mundi MS, Spaniolas K, Abu Dayyeh BK, Ghanem OM.Preoperative duration of type 2 diabetes mellitus and remission after Roux-en-Y gastric bypass: A single center long-term cohort study. Int J Surg. 2024;110:6214.
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DS/SADI

18
PaulAnthonyKaram, SarahSamreen, AndrewLin, andMaherEl Chaar

Introduction

Robotic-assisted (RA) surgery offers a unique set of advantages over traditional lapa­roscopic techniques, including enhanced precision, improved dexterity, and three­dimensional visualization [1]. Those advantages have resulted in an increased adoption rate in metabolic and bariatric surgery (MBS). In a recent manuscript by Bauerle etal., there was a nationwide increase in the utilization rate of RA approach in MBS between 2015 and 2020 according to the Metabolic and Bariatric Surgery Accreditation and Quality Improvement Project (MBSAQIP) data [2]. However, the use of the RA approach in MBS remains controversial for various reasons. To start, studies comparing the outcomes of RA-MBS to standard laparoscopic techniques based on MBSAQIP have shown conicting results [36]. The conicting results may be due to selection and exclusion criteria, matching processes, and differences in the denition of the outcome measures utilized in the studies [7]. In a recent study, we suggested the use of a standardized denition of outcome measures in comparing the RA approach to the standard laparoscopic approach using MBSAQIP data [8].
In addition, most studies have shown increased operation length and increased
healthcare costs [3, 9].
In our center, however, we have shown that the application of the RA approach for the performance of MBS is not associated with increased healthcare costs compared to the standard laparoscopic approach [10, 11]. We have also shown that the stan­dardization of the surgical approach can result in improved operating room efciency as measured by operating room length, wheels in wheels out, and turnover time [12].
P. A. Karam · A. Lin · M. El Chaar (*) Bariatric Surgery Department, St Luke’s University Health Network, Bethlehem, PA, USA
S. Samreen Surgery, The University of Texas Medical Branch, Galveston, TX, USA
© The Author(s), under exclusive license to Springer Nature Switzerland AG 2025 S. Samreen et al. (eds.), The SAGES Manual of Robotic Surgery,
https://doi.org/10.1007/978-3-031-86927-3_18
215
216
P. A. Karam et al.
Therefore, standardization and experience can potentially improve operating room efciency and lower healthcare costs irrespective of which surgical approach is utilized.
In terms of patient selection, currently, most health insurance payers follow the 1991 National Institutes of Health (NIH) guidelines for approval [13]. In 2022, the ASMBS/ IFSO guidelines recommended MBS for individuals with a BMI>35, regardless of comorbidities, and patients with a BMI>30 with associated metabolic disease [14]. The choice of the appropriate MBS procedure depends on patient obesity- related health con­ditions, patient expectations, and preferences and surgeon expertise. The role of the sur­geon is to provide all the information to help the patient make an informed decision [15].
Currently, the sleeve gastrectomy is the most performed MBS procedure fol­lowed by the Roux-en-Y gastric bypass (RYGB) [16]. Biliopancreatic diversion with duodenal switch (BPD-DS) and the single-anastomosis duodenoileal bypass with sleeve gastrectomy (SADI-S) are less commonly performed but are gaining popularity thanks to the RA approach. According to a recent study, up to 28% of BPD-DS are performed using an RA approach [2].
The rst biliopancreatic diversion with duodenal switch (BPD-DS) that we know today was rst performed in 1988 [17]. The advantage of BPD-DS over RYGB includes higher weight loss in patients with a BMI>50 and better diabetes remission rates [18]. However, given the complexity of this procedure and the increased adverse events compared to RYGB [1921], BPD-DS is not commonly performed and constitutes less than 2% of the overall number of MBS cases performed in 2020 [16]. Variations in the lengths of the alimentary limb and common channel have been described, with observed increased vitamin absorption and decreased number of daily bowel movements in patients with a longer common channel [22, 23]. At our institution, we prefer a longer common channel (200cm) over the standard 100cm to avoid long-term nutritional deciencies.
In 2007, a variant of the BPD-DS was introduced that involved creating a single anastomosis: the single-anastomosis duodenoileal bypass with sleeve gastrectomy (SADI-S) [24, 25]; by 2018, this procedure was established as a primary bariatric procedure.
SADI-S was shown to be associated with higher diabetes remission rates and similar weight loss results compared to RYGB [26]. Compared to BPD-DS, how­ever, the results of SADI-S are suboptimal [27, 28]. Although SADI-S is technically less challenging than BPD-DS, it is associated with higher early postoperative com­plication rates compared to RYGB when performed as a primary procedure [2931]. Interestingly, it has been shown to be as safe as RYGB when performed as a revi­sional procedure following sleeve gastrectomy [32].
At our institution, SADI-S is primarily offered as a revisional procedure to patients who have undergone previous sleeve gastrectomy and are suffering from weight recurrence, provided they do not have concomitant gastroesophageal reux disease.

Patient Preparation

Patient preoperative workup includes nutritional and psychological assessment, complete history with physical examination, upper endoscopy with biopsies to eval­uate for H. pylori, evaluation for obstructive sleep apnea, as well as cardiac
18 DS/SADI
217
evaluation. Revision patients may undergo upper gastrointestinal series, 24h pH studies or wireless pH studies, and high-resolution manometry as indicated. Patients are also screened for any increased risk for VTE and/or PE.
We employ an enhanced recovery pathway for our MBS patients. Enhanced recovery pathways differ among institutions and involve preoperative, intraopera­tive, and postoperative protocols [33]:
Prior to surgery, patients are placed on a liquid high-protein diet for 2weeks.
Although the benets of preoperative carbohydrate loading remain unknown, we have our patients consume a carbohydrate drink the night before and the morning of surgery as part of our pathway.
On the day of surgery, patients are given a preoperative dose of intravenous fosapre­pitant [34], intravenous acetaminophen, and oral celecoxib [35] with the aim of decreas­ing postoperative nausea and postoperative opiate use. Patients are also given DVT chemoprophylaxis and a single dose of intravenous antibiotics within 1h of incision.

Surgical Technique

The initial setup applies to all our bariatric procedures. We place the patient in the supine position with the arms out and secured to arm boards with web rolls. This allows us to keep the arms from falling off when positioning the OR bed without risking too much constriction on the limbs. A footboard is also placed to avoid patient slippage.
Fig. 18.1 Layout of robotic port placement
218
Fig. 18.2 Overhead view of operating room organization
P. A. Karam et al.
Our usual port layout includes four robotic ports and one assistant port, as shown in Fig.18.1. We start off by measuring approximately 15–20cm caudally from the xiphoid and slightly to the left of midline for our rst port, which will be our camera port. We then introduce a Veress needle through the incision to establish pneumo­peritoneum. For the patients who have undergone prior abdominal surgeries, we introduce the Veress needle at Palmer’s point.
Once a bilateral TAP block has been performed, we place our ports in a line per­pendicular to the midline at the same level as our initial camera port, ensuring that the distance from each port is at least 8cm. The second port from the patient’s right (robotic arm 2) will need to be a 12mm port to accommodate a robotic stapler. A 12mm assistant port is placed in the left lower quadrant, lateral to robotic arm 4. The assistant port is helpful for introducing sutures and gauze into the abdominal cavity without the need to remove any robotic arms and can also assist with retrac­tion. Once all the ports have been placed, a liver retractor is placed in the epigastric region for exposure.
The DaVinci robot will be positioned on the patient’s right, and the assistant will be on the patient’s left, as shown in Fig.18.2. Automatic targeting is completed using a robotic 30-degree endoscope, and the robotic arms are docked.

Single Anastomosis DuodenoIleal Bypass

Sleeve Gastrectomy
We start by placing the patient in the reverse Trendelenburg position at approxi­mately 15–20° to perform our sleeve gastrectomy. A Cadiere forceps is placed in arms 1 and 2 (arm 2 will be used most frequently while arm 1 is used to assist with retraction) and a vessel sealer in arm 4. Using the vessel sealer, we start by taking down the omental attachments along the greater curve staying close to the stomach. We carry this dissection all the way past the short gastrics and to the left crus. In