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J. Gootee and N. Szoka

Data Capture

The operative setting gathers and applies a wealth of data, encompassing various sources. These encompass information from the operating room, such as personnel details, system processes, and quality metrics. Additionally, data from surgical equipment, kinematic data from robotic platforms, and information from the surgi­cal eld, such as video streams from image-guided platforms, contribute signi­cantly. Moreover, there is a growing presence of integrated platforms aimed at enhancing data collection and exchange, often referred to as “Integrated Operating Rooms.”
Video Data
As digital technology progresses, the opportunities for recording and sharing surgi­cal videos have also advanced. These recordings encompass various aspects of the operative process and serve multiple purposes, including training, coaching, research, assessment, and quality improvement [4348]. With the introduction of 4K and 8K video resolution, the volume of surgical video data is growing rapidly. Additionally, there are numerous commercially available solutions for secure cloud storage of video data, facilitating the upload of surgical videos without the need for USB drives, DVDs, or encrypted drives.
The efcacy of utilizing video to enhance performance has been extensively documented across various disciplines. Numerous studies highlight the advantages of surgical video recording [38, 4754]. Medical trainees utilize videos to familiar­ize themselves with surgical anatomy, procedures, and technical intricacies, thereby preparing for cases more effectively. Curricula based on video content have demon­strated the ability to enhance knowledge base, improve technical performance, and shorten learning curves. Furthermore, a retrospective review of surgeons’ videos, supplemented with expert critique, has been shown to positively impact patient out­comes [55, 56].
Surgical videos have also found their way onto social media platforms, where surgeons seek peer feedback or advice on operative approaches. As the benets of intraoperative surgical video recording become increasingly apparent, surgeons per­forming open operations have begun adopting technologies to capture such cases. Saun etal. identied 176 clinical applications for open video recording and 125 different types of recording cameras used for capturing open intraoperative cases [48].
Multiple companies, including CMR Surgical, Intuitive, Medtronic, and Stryker, are developing visual medial platforms or “Hubs” that allow for video recording and storage, and enable video sharing or review, as well as virtual collaboration and learning. These systems can facilitate real-time consultation with offsite surgeons during challenging procedures.
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Data fromOperative Equipment
Kinematics refers to the examination of mechanical motion in points, bodies, and systems. In surgical robotics, kinematics serve the purpose of dening tool positions and joint positions concerning operator control and patient anatomy [40, 41]. Surgical robots have the capability to record precise instrument motion trajectories during procedures, allowing for the analysis of surgical activity beyond what tradi­tional instruments can provide [42]. Understanding surgeon kinematics not only offers insights into operative efciency but also aids in the development of autono­mous robots in the future. Moreover, other operative instruments contributing valu­able data include advanced energy devices and powered staplers, as discussed in the preceding section.
Data fromtheOperating Room andthe“Integrated Operating Room”
Several tools are in place to gauge OR efciency, among them surgical checklists and the Metric for Evaluating Task Execution in the Operating Room (METEOR). These tools undertake data collection, analysis, evaluation, iterative correction, and dissemination to staff and institutions [3537]. Drawing inspiration from the avia­tion industry’s use of a “black box” recording device to monitor extensive ight data for real-time and future analysis, similar approaches have been adapted for OR set­tings. Commercially available platforms like the OR Black Box (based in Toronto, ON, Canada) enable the capture of audio, visual, and other data related to various aspects of a procedure, both within the operative eld and the operating room itself (e.g., tracking team members). Articial intelligence and machine learning are employed to assist teams in enhancing quality and efciency. These systems are designed to detect and redact personal information of patients and providers while retaining clinically relevant data. Additionally, they have the potential to identify intraoperative errors, events, and distractions [38, 39].
Integrated or Digital Operating Rooms are setups designed to seamlessly inte­grate the OR environment, allowing different equipment sources to interact effec­tively. These installations often comprise high-resolution video displays, video routing systems, touch-screen controls, digital information archiving capabilities, and a central hub linking multiple ORs internally and externally. Besides streamlin­ing workows for surgical teams and enhancing safety measures, Integrated ORs facilitate live consultations with medical teams (e.g., pathology), real-time collabo­ration with virtual surgeons, data exchange with electronic medical record systems, and live feeds for training or educational purposes.
Caresyntax is a vendor-neutral, enterprise-focused surgical data platform that uses proprietary software and AI capabilities, to analyze extensive data streams, including video, audio, images, device data, clinical records, and operational
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metrics from operating rooms. This real-time information aids surgical teams dur­ing procedures and is accessible remotely via a telehealth link. Post-surgery, the platform offers invaluable insights for surgeons to benchmark and rene their prac­tices, enables hospital administrators to optimize resource allocation, supports med­ical device companies in developing superior products, and assists insurance companies in risk assessment and policy tailoring. Currently, the platform is deployed in over 2800 operating rooms globally, facilitating over 3million surgical procedures annually [a].
J. Gootee and N. Szoka

Data Analytics

Artificial Intelligence
The landscape of everyday life has been transformed by data analytics, driven by the convergence of three key trends: advancements in computer processors leading to faster and smaller devices, the application of proven statistical methods, and the availability of vast datasets. This transformation is now extending into health­care [13].
Articial intelligence (AI) stands out as a prominent area within analytics, char­acterized by its aim to develop systems capable of emulating human thought and behavior. In the context of surgery, AI applications often revolve around machine learning (ML), where machines can learn from data and make predictions by iden­tifying patterns. ML techniques, such as supervised and unsupervised learning, enable computers to make predictions based on partial data labeling or the inherent structure within the data [57].
A subset of machine learning called articial neural networks (ANNs) process signals through layers of simple computational units. ANNs excel in handling mul­tidimensional, covariate data, unlike traditional regression methods. Deep learning, which involves applying one or more ANNs to create systems capable of executing tasks autonomously or semi-autonomously, represents an exciting frontier in AI.
In healthcare, computer vision—a eld focused on machines’ understanding and interpreting pixelated data, such as images and videos—is gaining traction. While current applications are more prevalent in elds like radiology and pathology, computer- aided diagnosis is a rapidly growing area with signicant potential in healthcare [5459].
In surgery specically, AI holds promise in various areas, including real-time decision support, surgical education, risk prediction, process optimization, resource management, and even autonomous surgery.
Surgical Decision-Making
Across various surgical subspecialties, AI holds promise in predicting outcomes, preventing complications and missed diagnoses, alleviating the cognitive burden on
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busy physicians, and facilitating more informed discussions between physicians and patients [60]. AI applications in image recognition have particularly signicant implications, aiding both radiologists and surgeons in disease detection and evaluation.
The application of AI in image recognition extends to enhancing endoscopic cancer screening, a technique proven to enhance adenoma detection during colonos­copy [61]. Moreover, computer vision has been employed intraoperatively. Evidence suggests that many surgical adverse events stem from errors in judgment and deci­sion-making during surgery. AI presents a potential solution by augmenting sur­geons’ mental models during procedures.
Proof-of-concept algorithms have been developed primarily in the context of laparoscopic cholecystectomy. Examples include GoNoGoNet, which identies safe and dangerous areas of dissection to prevent major bile duct injuries, and CVSNet, which conrms the achievement of a Critical View of Safety [62, 63]. Additionally, ML algorithms are utilized in patient ow and operative resource management tasks, including estimating case length, coordinating between the operating room and post-anesthesia care unit, and predicting case cancellations [64].
Skills Assessment
Peer-rated surgical skill strongly correlates with surgical outcomes, demonstrating predictive power even when surgeries are not rated by other surgeons [65]. Skill assessments can even be performed by trained lay individuals with similar predic­tive accuracy [66]. The eld of automated skill assessment explores whether AI systems can perform similar assessments of surgeon skill automatically. Such sys­tems could play a crucial role in resident training and evaluation, as well as in men­toring or providing remediation for practicing surgeons.
Currently, AI skill assessment systems that have shown promising results in tri­als typically combine automated kinematic metrics with skill metrics generated by human observers. These metrics are then fed into neural networks (NN) for analy­sis [67]. However, fully automated skill assessments remain challenging, particu­larly due to the complexity of evaluating skills such as tissue respect and needle handling.
Despite the challenges, AI-generated assessments of technical skill have demon­strated good agreement with human graders for specic surgical tasks. Nonetheless, issues persist regarding consistency, generalizability, and the ability to provide actionable feedback to surgeons [68, 69].
Patient Care
Utilizing the extensive American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) database, a predictive algorithm based on machine learning was developed to enhance risk prediction [70]. NNs have
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demonstrated effectiveness in detecting breast, skin and lung cancers, as well as in predicting outcomes for surgical patients [7173].
In critical care settings, AI-driven tools have the potential to forecast clinical deterioration in patient hours before it occurs. Experimental systems have shown promise in autonomously determining appropriate treatment strategies for patients once they deteriorate [74, 75]. For instance, a machine learning-based hypotension prediction algorithm has been shown to reduce the time spent in a hypotensive state compared to standard care in a randomized single-center trial [76]. AI systems can be utilized to augment and lessen the burden on physician’s decision-making [77].
Automated Surgery
Surgery demands prociency in several fundamental areas: perception (the ability to discern tissues and planes), intelligence (the capacity to decide how to manipu­late tissues), and dexterity (the skill to manipulate tissues themselves). Various autonomous or semi-autonomous surgical systems already exhibit some or all of these capabilities, including the CyberKnife system that is utilized for stereotactic body radiotherapy [78].
In the realm of abdominal and soft-tissue surgery, the pliability, distensibility, and complexity of tissues pose challenges to AI autonomy. Present robotic plat­forms, like the DaVinci Surgical System, primarily function as surgical “assistants,” stabilizing instruments and interpreting movements rather than executing move­ments themselves. Nevertheless, there is optimism regarding the potential for auton­omous surgery to expand into gastrointestinal procedures. In laboratory settings, autonomous surgical AIs have demonstrated prociency in basic tasks such as cut­ting simulated 2D and 3D tissues and peg transfer [79, 80].
Among these developments, the Smart Tissue Anastomosis Robot (STAR) stands out as one of the most feature-complete AI systems for automated soft-tissue sur­gery. STAR, an automated suturing robot, has, in porcine models, successfully com­pleted laparoscopic bowel anastomoses [81]. However, it is worth noting that despite these advancements, this AI system still relies on an experienced surgeon to align and suture the bowel for anastomosis.

Connectivity

The digital surgery aspect of connectivity encompasses innovative methods of link­ing surgeon to surgeon, such as telementoring in educational and clinical settings, as well as connecting surgeon to patient through telesurgery.
Several factors converge to necessitate increased access to surgical care and edu­cation beyond the traditional model of in-person surgery. The most apparent factor is the constraints imposed during the COVID-19 pandemic. Virtual access became imperative as in-person attendance became challenging or impossible. This chal­lenge affected everyone from students contemplating a career in medicine to surgi­cal residents and fellows. Practicing surgeons were also impacted. Those motivated
9 Digital Surgery
to enhance their surgical skills found themselves unable to attend training courses or have proctors visit their facilities. Many sites had to suspend elective operations completely secondary due to equipment limitations or hospital capacity.
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Telementoring
Even prior to the onset of the COVID-19 pandemic, there has been a growing dis­parity between the available learning opportunities and surgical learners. The num­ber of students and trainees surpassing the capacity of hospitals to offer adequate access to operative training experiences. This issue has been exacerbated by the implementation of work-hour restrictions and decreasing autonomy for learners.
Education
Given current surgical training program volumes and population growth rates, pro­jections indicate a potential decit of nearly 30,000 surgeons by the year 2030 [82]. Addressing this shortfall is estimated to require an additional investment of approxi­mately $10billion in training efforts. While this presents a signicant challenge, it also offers an opportunity to reevaluate training paradigms.
The SAGES Project 6 working group has identied ve key areas of basic tech­nical requirements for telementoring: safety, reliability, transmission quality, ease of use, and cost [83]. Additionally, elements of a digital surgery training experience include advanced analysis of surgical video, recording video for later review, and telestration [84].
Telementoring in the context of trainees differs from that for practicing surgeons due to factors such as a more variable skill set, work-hour limitations, the need to meet specic educational requirements, and the presence of a supervising attending.
A telementoring program designed for educational purposes should adhere to evidence-based practices in curriculum development, mentor evaluation, and men­tee assessment. Components of a “train the trainer” program and mentee develop­ment have been outlined as part of the SAGES Project 6 initiative by Augestad etal [85, 86].
Clinical Practice
Surgical telementoring for clinical practice has been effectively employed for over two decades in various capacities. For instance, in 1998, Rosser etal. utilized tele­proctoring to guide doctors in rural Ecuador, a safe laparoscopic cholecystectomy for patients [87]. Fast forward to 2020, amidst the COVID-19 pandemic, telemen­toring facilitated a valve-in-valve transcatheter mitral valve replacement for an 82-year-old patient through real-time bidirectional audiovisual communication and digital transmission of live videos, enabling direct observation of the operative eld by a remote proctor [88]. Numerous other instances of successful surgical
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telementoring leading to positive clinical outcomes have been documented in the literature [8992].
Two primary applications of surgical telementoring in clinical practice are vir­tual intraoperative consultation and skill acquisition. Skill acquisition involves sce­narios where a remote mentor surgeon guides the mentee through an entire operation. This application is particularly valuable for performing new or complex procedures, allowing surgeons to undertake such operations with virtual guidance from an expe­rienced proctor. It also enhances the capabilities of local hospitals to offer more complex procedures while mitigating risks associated with performing new or com­plex procedures without assistance.
Virtual Surgical Assist is another application wherein a surgeon can receive real­time intraoperative consultation during challenging operations, especially when physical consultation is not feasible or would cause delays. This approach can be useful during after-hours, in cases of unexpected ndings (such as masses or abnor­mal anatomy), or in settings where surgeons with the necessary expertise are not physically available. Virtual Surgical Assist brings advanced surgical expertise to local sites, thereby leading to reducing the amount of transfers to tertiary care facilities.
Currently, Skill Acquisition is actively growing, whereas Virtual Surgical Assist is not frequently utilized, primarily due to systemic limitations in implementa­tion [93].
Telesurgery
Telesurgery refers to remote surgeries conducted when the surgeon is not physically present at the patient’s location. Manipulation of tissues and equipment and visual­ization are achieved through teleoperation [94].
The pioneering instance of telesurgery occurred in 2001 with a transatlantic robotic cholecystectomy performed by Dr. Jacques Marescaux. In this groundbreak­ing procedure, the surgical team was located in NewYork while the patient was in Strasbourg, France [95, 96]. Subsequently, in 2003, two Canadian hospitals estab­lished the rst telerobotic surgical service, successfully completing 21 telerobotic surgeries without serious complications or the need for conversions to open opera­tions [97]. Most of the current experience in telesurgery involves the use of inani­mate models for simulation and training purposes [98, 99].

Robotic Surgical Platforms

Minimally invasive robotic-assisted surgery (RAS) since the late 1990s has served as a pathway to integrate technological advancements into minimally invasive surgi­cal techniques. Over the past decade, there has been a rapid increase in the number of robotic endoscopic and surgical platforms available [100].
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A study conducted in Michigan examining the use of robotic surgery reported a notable rise in the utilization of robotic surgery for general surgical procedures, increasing from 1.8% in 2012 to 15.1% in 2018, accompanied by a decline in lapa­roscopic surgery [101].
In the surgical eld, there are three primary types of robotic systems: active sys­tems, which autonomously perform preprogrammed tasks; semi-active systems, which allow for a combination of surgeon-driven and preprogrammed elements; and fully surgeon-dependent systems.
Robotic surgery platforms typically feature either open or closed consoles. In closed console systems, the surgeon can stabilize their head position for consis­tent viewing, leading to a standardized eld of view. On the other hand, open console systems do not restrict the operator’s head position, allowing for free movement during the operation. Although head movement in open console sys­tems may potentially decrease efciency, it enables improved communication between the surgeon and team members as the surgeon is not conned behind a closed console.
In the United States, currently there are four FDA-approved robotic platforms for general surgery. Table9.1 shows the aspects of each system that is either FDA or CE approved. The Senhance from Asensus Surgical, MIRA by Virtual Incision (the world’s rst miniaturized robotic system) and the Da Vinci Xi and Single Port Systems from Intuitive. Additionally, there are two platforms, Versius by CMR Surgical and Hugo by Medtronic, which are currently in use in Europe and awaiting FDA approval. The market for robotic surgical platforms continues to expand, with novel modalities emerging, featuring reduced costs and smaller sizes [102]. Currently, there are over 20 robotic surgical platforms under development, includ­ing SPORTTM Surgical System by Titan Medical, Ottava by Johnson & Johnson, Beta 2 by Vicarious Surgical, and MicroSurge by the DLR Institute of Robotics and Mechatronics.
An additional term to become familiar with is robot-assisted “digital laparos­copy,” which refers to robotic systems that can utilize familiar laparoscopic instru­ments and conventional trocars from laparoscopic surgery. This allows for greater control in laparoscopy and increased OR efciency. Currently, the Senhance and Versius systems enable a digital laparoscopy-type approach.
Signicant growth has also been observed in endoluminal robotics, particularly for laparoendoscopic single-port surgery (LESS) and natural orice transluminal endoscopic surgery (NOTES). These approaches aim to minimize collateral tissue damage. Examples of such systems include the NeoGuide endoscopy system, a computer-aided colonoscope utilizing real-time 3D computerized mapping to navi­gate the natural curves of the colon; the FlexR robotic system from Medrobotics Corp., a joystick-controlled single-port platform used in surgeries of the orophar­ynx, hypopharynx, and larynx; and STRAS from iCUBE, a exible endoscopic system developed for single-port intraluminal surgery.
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Connectivity
observation
Data capture/
analytics
Instrument usage Remote case
Advanced
instrumentation
instruments including
observation
Kinematic Telemonitoring
Analytics
Video Remote case
Instrument usage Telemonitoring
7 degrees of freedom
instruments including
7 degrees of freedom
enables remote case
Kinematic
Analytics
Video Senhance Connect
and haptic sensing
observation &
telemonitoring
Video Telementoring &
Inserted through a
telesurgery under
development
Telemetry data
Video
single port
V-wrist technology
J. Gootee and N. Szoka
Telemetry data
Versius Clinical
Insights for
analytics
Video
Touch Surgery for
analytics
gives full wristed
instruments
and minimizing hand
tremors
Closed 3D image Endowrist
Robotic
segments Console Enhanced visualization
mounted
Approved 4—Boom
Company FDA status
Intuitive
Surgical
Robotic
platform
Da Vinci Xi
Table 9.1 Comparison of robotic surgical platforms
Multi Port
Firey—NIR uorescence
imaging
Inc
Firey—NIR uorescence
imaging
Eye tracking camera control
Closed 3D image Endowrist
mounted
Approved 4—Boom
Intuitive
Surgical
Da Vinci Xi
Single Port
Inc
Approved Open 3D image 7 degrees of freedom
Surgical
Senhance Asensus
Intelligent Surgical Unit™
(ISU™) for machine vision
available in EU
camera
NIR uorescence imaging
under development
Open Robotically controlled
Approved 2—Table
Mira Virtual
Open vLimeLite NIR uorescence
mounted
CE approval,
Incision
Versius CMR
imaging
awaiting FDA
approval
surgical
Open 3D image 7 degrees of freedom
awaiting FDA
approval
Hugo Medtronic CE approval,
NIR near infrared, EU European Union
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Barriers toImplementation
Multiple barriers are present in all domains of digital surgery, including advanced visualization, enhanced instrumentation, data capture, analytics, increased connec­tivity, and robotic surgical platforms. One major barrier includes the cost of imple­mentation of newer technological devices and showing that the benets of these devices offset the increased costs. An additional concern raised with the increased collection of data is concerns for patient condentiality and sharing patient data.

Conclusion

Digital surgery represents an emerging technology with signicant potential to add value across all tiers of the healthcare system. It includes multiple domains, includ­ing advanced visualization, enhanced instrumentation, data capture, analytics, increased connectivity, and robotic surgical platforms. These technologies herald a transformative revolution that will profoundly impact the surgical landscape. Surgeons occupy a pivotal role in steering these advancements and collaborating with other stakeholders to uphold the utmost safety and quality within this evolving paradigm. Their unique expertise and insights are crucial for navigating the integra­tion of digital surgical innovations effectively. Through active engagement and col­laboration, surgeons can ensure that these technologies are harnessed to their fullest potential, ultimately enhancing patient outcomes and advancing the eld of surgery.
Author Disclosures Dr. Szoka is the founder of Endolumik Inc. and a consultant for CSATS.

References

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