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eicosanoids, 296

Cushing’s disease, 268

cAMP-responsive element

histamine, 294

eicosanoids, 296

binding protein, 6, 354

serotonin, 294

epilepsy, 338

cancer see tumor

bronchial arteries, 176, 214

gastrectomy, 148

Candida albicans, 142

bronchial carcinoma, 16

heart, 182, 188, 226

capillary pulsation, 200

bronchiectasis, 162

hemostasis, 60

caput medusae, 170

bronchitis, 72, 76f, 214

hyperkinesias, 314

carbohydrates (see glucose

bronze disease, Addison’s

inflammation, 48

etc.), 244ff

disease, 252, 270

magnesium, 126

carbon monoxide, 84, 236,

Brown-Sequard’s

malabsorption, 152

346

syndrome, 318

nerve cells, 300

Carbonate, see HCO3

brush-border, 152

pancreatitis, 158

carbonic anhydrase,

Bruton-type tyrosine

renal excretion, 94, 98

acidosis, 88

kinase, 58

renal hypertension, 114

gastritis, 142

Budd-Chiari syndrome, 170

somatotropin, 262

glaucoma, 322

Buerger’s disease vasculitis,

stroke, 360

renal transport, 96

240

urolithiasis, 120f

γ-carboxylation, 60

buffalo hump, 268

renal disease, 106110ff

carcinoid, 142, 294

buffer, 86ff, 130

Ca2+ channel blockers, 182,

Carcinoma, see tumor

bulimia, 26, 40

188, 220, 226

cardiac arrest, 24, 186ff

bundle branch block, 188

defects, 306

cardiac arrhythmias

burning, 240

epilepsy, 338

see arrhythmia

burns, bradykinin, 294

heart, 182,188

cardiac contractility, 224ff

circulatory shock, 230

hyperthermia, 22

acidosis, 90

gastritis, 142

insulin release, 292

circulatory shock, 232

histamine, 294

neuromuscular trans-

histamine, 294

peptic ulcer, 146

mission, 304

insulin, 288

porphyria, 254

renal transport, 98

thyroid hormones, 282ff

salt balance, 122

Ca2+ receptor, 98ff, 126, 128ff

cardiac excitation (see as well

burst-forming units, 32

Ca2+ spark, 182

myocardial, heart), 176f

2,3-butyleneglycol, 110

Ca2+-ATPase, 182, 226

cardiac glycosides

b-wave, electroretino-

Cabrera circle, 184

(see digitalis), 182

gram, 324

cachectin, 20

cardiac index, 176

bypass, 220

cachexia, 16, 20, 26f

cardiac muscle, 4, 224ff

 

cacosmia, 330

cardiac nerves, 182

C

cadmium see Cd2+

cardiac output, 176ff

caecum, 134

aging, 18

 

caffeine, 100

circulation, 176

C reactive protein, 50

CaHPO4 see Ca2+

hyperthyroidism, 282

C3a, 50, 294

calcification, 228, 238

portal hypertension, 170

C3b, 44, 50

calcitonin, 6

respiration, 66

C4a, 50

calcitonin gene-related

cardiac rhythm, 186ff

C5a, 50, 294

peptide, 320

cardiac valves, 178, 194ff

Ca2+ (see Ca2+ channels),128ff

calcitriol, 128ff

cardiogenic shock, 222, 230

acidosis, 88

calcium, see Ca2+

cardiomegaly, 244

alkalosis, 90

calmodulin, 7

cardiomyopathy, circulatory

antidiuretic hormone, 260

CaM kinase, 7

shock, 230

bone, 132

cAMP, 6f

heart failure, 224

breathing regulation, 82

antidiuretic hormone, 260

hemochromatoses, 252

cell death, 12

coronary circulation, 216

thromboembolism, 240

cholelithiasis, 164

cystic fibrosis, 162

caries, 140

cirrhosis, 172

diarrhea, 150

carotid, 360

consciousness, 342

histamine, 294

carpal tunnel syndrome, 262

CSF, 356

opiate receptor, 354

cartilage, 250, 262

br

ca

Index

371

Silbernagl/Lang, Color Atlas of Pathophysiology © 2000 Thieme

All rights reserved. Usage subject to terms and conditions of license.

ca

ch

Index

372

caspases, 12

chronic renal failure, 112

CGRP (calcitonin gene related

catabolism, diabetes

consciousness, 342

peptide), 320

mellitus, 288

eicosanoids, 296

Chagas’ disease, 156

inflammation, 50

epilepsy, 338

channel defects, 306f

thyroid hormones, 282

insulin, 288

Charcot-Maire-Tooth,

tumor, 16

pancreatitis, 158

302, 306

catalase, 42, 254

portal hypertension, 170

Chediak-Higashi

cataract, 290f, 322f

signal transmission, 7

syndrome, 58

catecholamines

stroke, 360

chemokines, 48

(see [nor]epinephrine),

central nervous sytem

chemoreceptor trigger

Addison’s disease, 270

see nervous system

zone, 140

bradykinin, 294

central venous pressure,

chemoreceptors, 140, 148

breathing regulation, 82

176ff

chemotaxis, 42ff, 238, 296

coronary circulation, 216

circulatory shock, 230

chemotherapeutic

Cushing’s disease, 268

salt balance, 122

agents, 58, 274

depression, 350

centralization, 226, 232

chenodeoxycholate, 164

heart failure, 226

centrilobular emphysema

Cheyne-Stokes breathing,

histamine, 294

see emphysema

82

hypertension, 208, 212

centriole, 2

chief cells, 144

potassium balance, 124

ceramide, 7, 12

Chlamydia pneumoniae, 236

thyroid hormones, 282

cerebellum, 316ff

chloride see Cl

catechol-orthomethyl-trans-

basal ganglia, 312

chlorophenylalanine, 350

ferase, 250

depression, 350

cholangitis, 166ff, 174

cation channels, 300, 304

descending motor

cholecystectomy, 166

caudate nucleus, 312, 344

tracts, 310

cholecystitis, 166

CCK (cholecystokinin),

memory, 346

cholecystokinin see CCK

cholelithiasis, 166

multiple sclerosis, 302

choledochal duct, 160

esophagus, 136

sensory system, 318

cholelithiasis, 164ff

gastrectomy, 148

stroke, 360

cholera toxin, 6, 150

insulin release, 292

vestibular system, 330

cholestasis, 166ff, 174

malabsorption, 152

cerebral blood flow

cholesterol, 244ff

signal transmission, 7

see blood flow, brain

adrenocortical

CCR5, 58

cerebral cortex,

hormones, 264

CD18, 58

depression, 350

atherosclerosis, 236

Cd2+, 38, 330

EEG, 336

cholelithiasis, 164,168

CD4, 45, 58

memory, 346

female sex hormones, 276

CD40, 45, 58

vestibular system, 330

hepatorenal syn-

CD8, 44, 56

cerebral edema, 358ff

drome, 118

CD95 (Fas/Apo1), 7, 12, 16, 45

antidiuretic hormone, 260

inflammation, 48

cdc2, 2

chronic renal failure, 110

nephrotic syndrome, 104

celiac disease, 54, 154

hypertension, 212

thyroid hormones, 282ff

cell cycle, 2

salt balance, 122

cholesterol-ester storage

cell death, 10ff

cerebral infarction

disease, 244

Alzheimer’s disease, 348

see stroke

cholesteryl ester, 246

hyperkinesias, 314

cerebrospinal fluid, 22, 356f

cholestyramine, 154, 247

nerve cells, 300

ceruloplasmin, 38, 252

choline, 304

stroke, 360

cervix, 2, 276

choline-acetyl transferase,

cell growth, see proliferation

CF see cystic fibrosis

348

cell volume, 122f

CFTR see cystic fibrosis

cholinergic, 332f

acidosis, 90

CFU-E see colony forming

Alzheimer’s disease, 348

Alzheimer’s disease, 348

units

basal ganglia, 312

antidiuretic hormone, 260

cGMP, 6

Parkinson’s disease, 314

cell death, 10ff

coronary circulation, 216

chondrocytes, 2

cerebral edema, 358

inflammation, 48

chorda tympani, 330

Silbernagl/Lang, Color Atlas of Pathophysiology © 2000 Thieme

All rights reserved. Usage subject to terms and conditions of license.

chordae tendineae,

cystic fibrosis, 162

cold (see hypothermia),

194, 196, 222

diarrhea, 6, 150

48, 318

chorea, 314

eicosanoids, 296

cold intolerance, 284

choriomammotropin, 286

epilepsy, 338

colic, 120, 166

choroid artery, 360

magnesium, 126

colipase, 152

choroid plexus, 356

myotonia, 306

colitis, 156

choroid vessels, 324

clasp-knife effect, 310

collagen, athero-

chronic bronchitis

class jump, 45

sclerosis, 238

see bronchitis

clathrin, 246

bone, 132

chronic occlusive arterial

claudication, vasculitis, 240

cell growth, 4

disease, 238

clearance renal, 94, 104

cirrhosis, 172

chronic renal failure, 110ff

click, 200

Cushing’s disease, 268

chronotherapy, 340

clonal deletion, 42, 56

diabetes mellitus, 290

chronotropism, 332

clonal expansion, 45

heart failure, 226

chylomicrons, 154, 246ff,

clonal selection, 42, 45

hemochromatoses, 252

288

clonic cramps, 338

hemostasis, 60

chyme, gastrointestinal

clonidine, 350

hypothyroidism, 284

tract, 134, 148

Clostridium difficile, 150

restrictive lung disease, 74

chymotrypsin, 152

clotting, see blood clotting

somatotropin, 262

cilia, 76

clotting tests, 62

tissue repair, 50f

ciliary body, 322

clubbed toes, 204

collecting ducts, 98ff, 124,

cingular gyrus, 320, 352

CNS (central nervous system)

260

circadian rhythm, 334, 340

see nervous system

colloidal osmotic

circulation, 176ff

CO see cardiac output and

pressure, 234

acidosis, 88

carbonmonoxide

colon, 150, 156, 160

hypothalamus, 334

CO2, acidosis, 88

colony-forming units, 32

hypoxia, 84

alkalosis, 86, 90

colony-stimulating factor, 28

circulatory shock, 176, 230ff

breathing regulation, 82

color vision, 324f

anemias, 36

diffusion abnormal-

coma, 342f

pancreatitis, 158

ities, 70

aortic stenosis, 198

peptic ulcer, 146

distribution abnormal-

calcium, 128

pericarditis, 228

ities, 72

cerebral edema, 358

pulmonary hypertension,

respiration, 66ff

chronic renal failure, 110

214

sensory system, 318

circulatory shock, 232

circulatory shunts, 204 ff

Co2+, 38

diabetes mellitus, 288

circumventricular organs,

CO 2, 132

epilepsy, 338

 

3

 

356

coagulation, 60ff

gastrectomy, 148

cirrhosis, see liver cirrhosis

bradykinin, 294

hyperthermia, 20ff

cisplatin, 328

Cushing’s disease, 268

hypoglycemia, 292

11-cis-retinol, 324

female sex hormones, 276

hypothyroidism, 284

citrate, diarrhea, 150

coagulopathies, 62ff

liver failure, 174

hemostasis, 62

coated pit, 246

phosphate, 130

pancreatitis, 160

cobalamine, 34f

porphyria, 254

urolithiasis, 120

folate, 34

salt balance, 122

citrus fruits, 138

gastrectomy, 148

stroke, 360

c-Jun, 7

gastritis, 142

coma dépassé, 342f

c-kit ligand, 28

hemostasis, 64

commissural fibers, 336, 342

CK-MB (creatine kinase

malabsorption, 134, 152ff

compatibility, 40

muscle, brain), 222

cocaine, addiction, 354

compensatory pause, 186

Cl, cell death, 10

myocardial infarction, 222

complement, 42ff, 50ff

cystic fibrosis, 162

olfaction, 330

fever, 20

renal transport, 98ff

schizophrenia, 352

hemolytic anemias, 40

Clchannels, apoptosis, 12

taste, 330

histamine, 294

Bartter syndrome, 98

colchicine, 154

pancreatitis, 158

ch

co

Index

373

Silbernagl/Lang, Color Atlas of Pathophysiology © 2000 Thieme

All rights reserved. Usage subject to terms and conditions of license.

co

cy

Index

374

compliance, heart, 204, 220

Cori, 244

craniotabes, 132

lung, 74, 80

cornea, 84, 252, 322f

creatine, 308

COMT (catechol-orthome-

coronary circulation, 76,

creatine kinase, 222, 308

thyl-transferase), 350

216ff

creatinine, 92ff, 110, 308

concave lens, 322

aortic regurgitation, 200

CREB (cAMP responsive

concentrating mechan-

aortic stenosis, 198

element binding protein),

ism, 100f, 110, 260

vomiting, 140

6, 354

concentric hypertrophy, 198

coronary heart disease, 218ff,

crescendo murmur, 194

conditioning, 346

224, 236ff

cretinism, 284

conducting system,

circulatory shock, 232

Creutzfeldt-Jakob disease,

heart, 180, 190

lipoprotein, 247

348

conduction nerves, 302, 306

mitral regurgitation, 196

CRH, see corticotropin

conductive hyposmia, 330

corpus callosum, 342

releasing hormone

cones, 324

corpus luteum, 12, 274f

cribriform plate, 330

confabulations, 346

corpus striatum, 312

Crigler-Najjar syndrome, 168

confusion, 22, 110, 348f

cortex, see cerebral cortex

Crohn’s disease, 154, 164

congestive liver, 172

cortical blindness, 326

CRP (c-reactive protein), 50

congestive shock, 230

cortical tracts, 310

crystals, acute renal failure,

conjunctivitis, 294

corticoliberin, see cortico-

108

Conn’s syndrome, 212, 266

tropin releasing hormone

cholelithiasis, 164

connective tissue, 236

corticospinal tracts, 312

gout, 250

connexin, 302

corticotropin, 264f

inflammation, 50

consciousness, see coma

autonomic nervous

urolithiasis, 120

consensual reaction, 326

system, 332

CSF (colony stimulating

constipation, 156f

breathing regulation, 82

factors), 28

calcium, 128

hypothalamus, 334

CSF (cerebrospinal

hypothyroidism, 284

signal transmission, 6

fluid), 356f

magnesium, 126

corticotropin-releasing

CSFs blood, 28

porphyria, 254

hormone, 20, 266f

CTZ (chemoreceptor trigger

constrictive pericarditis, 228

Alzheimer’s disease, 348

zone), 140

contact dermatitis, 54

adrenocortical

curare, 304

contact inhibition, 4

hormones, 264

Cushing’s disease, 210ff,

contact lens, 322

cortisol, 258, 264ff

266 ff, 286

contraceptive pills, 274f

apotic cell death, 12

cuts, 48

cholestasis, 168

bone, 132

CVP, see central venous

hypertension, 212

diabetes mellitus, 286ff

pressure

venous disease, 240

eicosanoids, 296

c-wave (electroretinogram),

contractility, see cardiac

female sex hormones, 276

324

contractility

hypertension, 208, 212

CXCR4 (chemokine receptor),

conversion, Hormones, 256

hypoglycemia, 292

58

converting enzyme, 210

hypothalamus, 334

cyanide, 330

convex lens, 322

lipoproteins, 246

cyanosis, (see hypoxia),

convulsions, alkalosis, 90

obesity, 26

70, 80, 84f, 204

calcium, 128

peptic ulcer, 146

cyclic adenosine monophos-

fever, 20

phosphate, 130

phate, see cAMP

gastrectomy, 148

somatotropin, 262

cyclines cell growth, 2, 14

glycogen storage

thyroid hormones, 280

cyclo-oxygenase, 7, 296

disease, 244

tumors, 16

fever, 20

magnesium, 126

cosmetics, 54

hemostasis, 64

phosphate, 130

coughing, hyperoxia, 84

peptic ulcer, 146

copper, 20, 38, 252f

coumarin, 64

cyclosporin A, 45, 168

coproporphyrins, 254

coxsackievirus, 228

cystathionine-β-

cor pulmonale, 74ff,

51Cr, 32

synthase, 242

214f, 244

cramps, see convulsions

cysteine, see cystine

Silbernagl/Lang, Color Atlas of Pathophysiology © 2000 Thieme

All rights reserved. Usage subject to terms and conditions of license.

cystic fibrosis, 162f

decay accelerating factor, 40

desipramine, 350

cholestasis, 168

decompensation, heart

desulfiram, 354

liver failure, 174

failure, 224f

deuteranomaly, 324

malabsorption, 152

decomposition of movement,

deuteranopia, 324

obstructive lung disease,

316

deviation conjugée, 360

76

decorin, 172

D-glycerate dehydrogenase,

cystic fibrosis transmem-

decrescendo murmur, 200

242

brane conductance

dedifferentiation, 2

DHEA (dehydroepiandros-

regulator, 162

defecation, 156, 332

terone), 268

cystine, 242

defensins, 44

DHT (delayed hypersensitiv-

acidbase, 86ff

defibrillator, 190

ity type) cells, 54

malabsorption, 154

degenerative disease, 302,

diabetes insipidus, 98ff, 122,

renal transport, 96

316, 348

260f, 334

urolithiasis, 120

deglutition, 136

diabetes mellitus, 286ff

cystinosis, 242

dehydration, 122ff, 260f

acidosis, 88

cystinuria, 96, 120f, 154, 242

Addison’s disease, 270

apotic cell death, 12

cytochrome c, 12, 254

diabetes mellitus, 288

atherosclerosis, 236

cytokines, 20, 48, 268

gastrectomy, 148

autoimmune diseases, 56

cytokinesis, 2

7-dehydrocholesterol, 132

bone, 132

cytolysis, 44f, 52

dehydro-epiandros-

cataract, 322

cytomegalovirus, 142

terone, 268

cerebral edema, 358

cytoprotection, 144

Dejerine-Sottas

circulatory shock, 230

cytoskeleton, 40

syndrome, 302

consciousness, 342

cytostatica, 58, 274

delayed hypersensitivity, 54

constipation, 156

cytotoxic edema, 358

delayed sleep phase

Cushing’s disease, 268

cytotoxic T cells, 44, 58

insomnia, 340

female sex hormones, 276

 

deletion phenomenon, 318

heart failure, 226

D

delusions, 352

hemochromatoses, 252

dementia, 312, 336, 348 f

hyperthyroidism, 282

 

demineralization of

kidney, 94, 102, 106

D1, D2 receptor, see dopamin

bone, 90, 132f

magnesium, 126

DAF (decay accelerating

demyelination, 302f

motor unit, 306

factor), 40

dendrites, 336

obesity, 26

DAG (diacylglycerol), 7

dendritic cells, 44, 54

pancreatitis, 160

dantrolene, 22

dentate nucleus, 316

phosphate, 130

DAPs (depolarizing after

deoxycorticosterone, 212

somatotropin, 262

potentials), 188

11-deoxycorticosterone,

taste, 330

D-CDK4, see cyclins

212, 264

vomiting, 140

DCT1 (iron carrier), 38

11-desoxycortisol, 264

diabetic coma, see diabetes

DDT, 316

deoxythymidylate, 34

mellitus

dead space, 68, 78

deoxyuridylate, 34

retinopathy, 324f

Deafness, 284, 328f

depolarization, 10, 188, 300

diacylglycerol, 7

death, 18f

(see action potential)

dialysis, 132, 358

aortic stenosis, 198

depolarizing after-poten-

diapedesis, 50

atherosclerosis, 236

tials, 188

diaphragm, 136

cerebral edema, 358

depression, 350f

diarrhea, 150ff

EEG, 336

Addison’s disease, 270

acidosis, 88

glycogen storage diseases,

hypothyroidism, 284

Addison’s disease, 270

244

Parkinson’s disease, 312

allergies, 52

heart failure, 226

sleep disorders, 340

choleratoxin, 6

hemochromatoses, 252

dermatome, 298, 318

chronic renal failure, 110

lipidoses, 244

dermatomyositis, 156, 306

circulatory shock, 230

muscular dystrophy, 306

dermatosclerosis, 240

eicosanoids, 296

debrancher enzyme, 244

Descemet’s membrane, 252

gastrectomy, 148

cy

di

Index

375

Silbernagl/Lang, Color Atlas of Pathophysiology © 2000 Thieme

All rights reserved. Usage subject to terms and conditions of license.

di

ec

Index

376

hyperthyroidism, 282

potassium, 124

DR3/DR4, 56

malabsorption, 154

urinary concentration, 100

dromotropism, 90, 182f, 332

pancreatitis, 160

distribution abnormali-

drooping mouth, 360

salt balance, 122

ties, 72f, 78

drowsiness, 342

serotonin, 294

diuresis (see as well poly-

Dubin-Johnson

tumors, 16

uria), 98ff, 120ff, 294ff

syndrome, 168

diastole, 178f

diuretics, 98ff

Duchenne’s dystrophy, 306

aortic regurgitation, 200

cardiac rhythm, 188

ductus arteriosus, 202, 296

blood pressure, 206

circulatory shock, 230

duodenum, 144ff, 268

coronary circulation, 216

phosphate, 130

dumping syndrome,

heart failure, 224

potassium, 124

148f, 292

mitral stenosis, 194

diurnal rhythm, 266, 340f

duodeno-pancreatic

DIC (disseminated intra-

diverticulum, 156

reflux, 158

vascular coagulation),

diving, 84

duodenum, 144ff, 158ff,

64f, 230

dizziness, 330f

252, 268

diclofenac, 146

aortic stenosis, 198

dwarfism, 132, 262, 272ff

diencephalon, 346

cerebral edema, 358

d-wave (Electroretino-

diet, 26, 242, 247

hyperoxia, 84

gram), 324

diffusion, 70ff, 78ff, 84

hyperthermia, 22

dysdiadochokinesia, 316

DiGeorge’s syndrome, 58

stroke, 360

dysesthesia, 318

digestion, 134

DNA damage iron, 252

dysgeusia, 330

digitalis, 182f, 188ff

DNA repair, 14, 316

dyskinesia, 222 ff

calcium, 128

DNA synthesis, 34

dysmetria, 316

hypertension, 114, 210

DNA fragmentation, 12

dysmorphopsia, 326

renal failure, 112

DNA-helicase, 18

dysphagia, 138

salt balance, 122

DOC, see deoxycorticosterone

dysphoria, 354

vomiting, 140

dopamine, 312ff, 352ff

dyspnea, 66

7,8-dihydrofolate, 34

addiction, 354

aortic stenosis, 198

dihydrofolate reductase, 34

adrenocortical

coronary heart disease,

dihydropyridine, see Ca2+

hormones, 266

220

channel blockers), 226

antidiuretic hormone, 260

heart failure, 226

dihydropteridine reductase,

basal ganglia, 312

mitral stenosis, 194

242

depression, 350

pericarditis, 228

dihydropyramidole, 182

esophagus, 136

dysproteinemia, 64

dihydrotestosterone, 272

female sex hormones, 274

dysrhythmia, 186

diiodotyrosine, 280

memory, 346

dyssynergia, 316

dilator pupillae, 332

Parkinson’s disease, 314

dystonia, 314

diltiazem, 188

prolactin, 260

dystrophin, muscular

dipeptides, 134, 154

schizophrenia, 352

dystrophy, 306ff

diphenylhydantoin, 316

signal transmission, 6

dystrophy, 306

2,3-diphosphogycerate, 84,

somatotropin, 262

dys-β-lipoproteinemia, 247

130, 282, 290

thyroid hormones, 280

 

diplopia, 282

vomiting, 140

E

disaccharidase, 152

dopaminergic drugs,

disc prolapse, 132

see dopamine

 

disopyramide, 188

dorsal column, 318

E receptor, 247

disorientation, see confusion

Down’s syndrome, 348

E2 F, 14

Dissé space, 172

down-regulation of

eating center, 26

disseminated intravascular

receptors, 6f

Eaton, 304

coagulation, 64f, 230

androgens, 272

Ebstein’s anomaly, 202

distal diuretics, 98

diabetes mellitus, 286

E-CDK2, see cyclines

distal tubule, 98f

female sex hormones, 274

ECG (electrocardio-

antidiuretic hormone,

nerve cells, 300

gramm), 124, 128,

260

DP1, 14

178, 184ff

Silbernagl/Lang, Color Atlas of Pathophysiology © 2000 Thieme

All rights reserved. Usage subject to terms and conditions of license.

echinocytes, 168

electrolytes (see Na+, K+, Ca2+,

hepatorenal syndrome,

echocardiogram, 194

Cl, etc.), 92ff, 356

118

echovirus, 228

electromyography, 308

icterus, 168

ECL (enterochromaffin-like)

electrophoresis, 104

end-plate, 304

cells, 142ff, 294

electroretinogram, 324f

endsystolic volume, 178, 200

ectopic atrial depolariza-

embolism, see thrombo-

energy, 2ff, 130, 300, 338

tions, 186

embolism

enflurane, 22

ectopic hormonal produc-

embryonic development, 12

enophthalmos, 332

tion, 256, 260ff,

emetic, 140

enterochromaffin cells, 294

266, 270

emotions, 334, 352

enterochromaffin-like (ECL)

ectopic pacemakers, 226

emphysema, 72, 76ff

cells, 142

edema (see as well pulmo-

ENaC (epithelial Na+

enterohepatic recircula-

nary edema), 234f

channel), 98, 162

tion, 168

alkalosis, 86

encephalitis, 212, 312ff

enteropeptidase, 158

chronic renal failure, 110

encephalopathy, 170, 174

enterotoxins, 140

constipation, 156

end-diastolic pressure,

entorhinal cortex, 346ff

eicosanoids, 296

198, 222

enzyme defects, 242ff

heart failure, 226

end-diastolic volume, 178

adrenal hormones, 264 f

hepatorenal syndrome,

endocardial fibrosis, 294

androgens, 272

118

endocarditis, autoimmune

cerebellum, 316

histamine, 294

diseases, 56

female sex hormones, 274

inflammation, 50

myocardial infarction, 222

pseudohermaphro-

liver failure, 174

thromboembolism, 240

ditism, 278

malabsorption, 154

valve defects, 194ff

thyroid hormones, 280f

nephrotic syndrome, 104

endocardium, 216

enzymes, 222, 242ff, 316

pain, 320

endocrine, 256

enzymopathies, see enzyme

pancreatitis, 158

endocrine psychogenic

defects

pericarditis, 228

syndrome, 268

eosinophils, 42, 48

pregnancy, 116

endocytosis, 247

Addison’s disease, 270

valve defects, 202

endolymph, 328

allergies, 52

venous disease, 240

endonuclease, 12

Cushing’s disease, 268

EDTA, 62

endopeptidases, 144

eotaxin, 48

EDV (end-diastolic

endorphines, addiction, 354

ephaptic transmission, 302

volume), 178

breathing regulation, 82

EPH-gestosis (edema,

EEG, 336f

cholestasis, 168

proteinuria, hypertension),

effective filtration

female sex hormones, 274

116

pressure, 102, 234

pain, 320

epidermal growth factor,

EGF epidermal growth

prolactin, 260

4, 14, 144

factor, 4, 14, 144

endostatin, 16

epididymis, 278

Ehlers-Danlos syndrome,

endothelium, athero-

epilepsy, 16, 330, 336ff, 342

238

sclerosis, 236ff

epinephrine (see as well

Eicosanoids, 296f

blood-brain barrier, 356

catecholamines), 332f

Einthoven, 184

cell growth, 2

adrenocortical hormones,

ejaculation, 272, 332

coronary circulation,

266, 270

ejection click, 202

216, 220

breathing regulation, 82

ejection fraction, 178

glomerular function, 102ff

chronic renal failure, 112

elastase, 78f, 158ff

hemostasis, 60, 64

circulatory shock, 232

elastin, 4, 238

histamine, 294

diabetes mellitus, 286ff

elderly, see aging

hyperoxia, 84

eicosanoids, 296

electric shock, 188ff, 346

inflammation, 48ff

esophagus, 136

electrical axis, 184

tumors, 16

heart, 226

electroacupuncture, 320

endotoxins, 50f

histamine, 294

electrocardiogram, 124, 128,

constipation, 156

hypertension, 212

178, 184ff

fever, 20

hypoglycemia, 292

ec

ep

Index

377

Silbernagl/Lang, Color Atlas of Pathophysiology © 2000 Thieme

All rights reserved. Usage subject to terms and conditions of license.

ep

fe

Index

378

potassium, 124

excitement, 24, 186

fatigue, Addison’s

signal transmission, 6f

excitotoxins, 348

disease, 270

tumors, 16

exhaustion, 24

fever, 20

vomiting, 140

exophthalmos, 282

glycogen storage diseases,

epiphyseal fusion, 262, 272,

exotoxins, 50

244

276

expiration, 66 ff, 186

heart disease, 226

Epstein-Barr virus, 12

extensors, 310

inflammation, 50

ErbA, B, 14

extracellular matrix, 4, 238

myasthenia gravis, 304

erection, 332

extracellular volume, 88,

sleep disorders, 340

ERG (electroretino-

122f, 130, 208ff

fatty acid, alkalosis, 86

gram), 324

extracorporeal circula-

calcium, 128

ERP (endoscopic retrograde

tion, 24

cholelithiasis, 166

pancreatography), 160

extrasystole, 186f

coronary heart

erythroblast, 32, 254

exudative enteropathy, 174

disease, 220

erythrocytes, 28ff, 36f

eye, 322ff

Cushing’s disease, 268

allergies, 52

autoimmune diseases, 56

diabetes mellitus, 286ff

cell growth, 2

diabetes mellitus, 290

gastrointestinal tract, 134

cholestasis, 168

hyperthyroidism, 282

kidney, 92, 118

CSF, 356

Wilson’s disease, 252

lipoproteins, 246

Cushing’s disease, 268

eye muscles, 330

magnesium, 126

nephrotic syndrome, 104

 

pancreatitis, 158,

phosphate, 130

F

170, 288

potassium, 124

favism, 40

erythropoiesis, 30ff

F132

Fc (crystallisable fragment),

androgens, 272

44ff

hemochromatosis, 252

Fab (antigen binding frag-

Fc receptor, 48

hyperthermia, 24

ment) inflammation, 48

Fe (see iron), 38ff, 252

thyroid hormones, 282ff

facial nerve, 330, 360

Fe2+-H+-symport, 38

erythropoietin, 28ff, 40f

factor I– XIII

feces, 134

circulatory shock, 232

see blood clotting

feedback, heme synthesis,

kidney, 92, 102, 110

Fallopian tubes, 276ff

254

somatotropin, 262

false transmitters, 174

hormones, 256ff, 272

thyroid hormones, 282

familial hypercholesterol-

female sex hormones

esophageal varices,

emia, 247

(see estrogens, proges-

62, 170, 174

familial incidence,

terone), 274ff

esophagitis, 138, 284

see genetic disposition

fenestra cochleae, 328

esophagus, 134, 136ff

familial LCAT deficiency, 118

fenestra vestibuli, 328

essential, amino acids, 242

familial protein intolerance,

ferrireductase, 38

essential hypertension, 208

96

ferritin, 38, 252

estrogens, 274f

Fanconi’s syndrome, 96,

fertility, 272ff, 284

adrenocortical hormones,

130ff

fetal circulation, 202

264

farmer’s lung, 54

fetus, 282ff

bone, 132

FAS, see CD95 (Fas/Apo1)

FEV1 (forced exspiration

cholestasis, 164, 168

fasciculations, 306

volume), 74ff, 80

hypothalamus, 334

fasting, see starvation

fever, 20f

intersexuality, 278

fat, aging, 18

acidosis, 88

kidney, 92, 116f

androgens, 272

blood pressure, 206

olfaction, 330

Cushing’s disease, 268

cholelithiasis, 166

prolactin, 260

female sex hormones, 276

eicosanoids, 296

somatotropin, 262

hypothyroidism, 284

epilepsy, 338

thyroid hormones, 280

insulin, 288

heart, 186, 194, 228

ESV (see endsystolic

lipoproteins, 246

pulmonary hypertension,

volume), 178

malabsorption, 152ff

214

euphoria, 354

somatotropin, 262

salt balance, 122

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FGF, see fibroblast growth

Forbes, 244

schizophrenia, 352

factor

forced expiration

vomiting, 140

fiber, 156

volume, 74ff, 80

galactitol, 244

fibrillations, 240, 306

Forskolin, 6

galactokinase, 244

fibrin (ogen), 60ff

Fos, 7, 14

galactorrhea, 16, 260

acute renal failure, 108

fovea centralis, 324

galactose, 150ff

atherosclerosis, 236

fractures, bone, 132

galactose-1-uridyl trans-

diabetes mellitus, 290

circulatory shock, 230

ferase, 244

pericarditis, 228

lipidoses, 244

galactosemia, 174, 244f, 292

pregnancy, 116

olfaction, 330

liver failure, 174

fibrinolysis, 28, 60ff

Frank-Starling aortic

gallbladder, 152, 164ff

fibroblast growth factor,

regurgitation, 200, 204,

gallstones, 164ff

4, 226, 348, 226

208, 230

constipation, 156

fibroblasts, 2, 44, 50f, 172,

free radicals, 18

obesity, 26

226

frequency filter, 186, 190

pancreatitis, 158

fibronectin, 4, 60, 172, 284

frequency inotropism, 182

ganglion cells, 324

fibrosis, cirrhosis, 172

Freund’s adjuvant, 56

GAP (GTPase activating

heart failure, 226

flexors, 310

protein), 14

pancreatitis, 160

Friedreich’s ataxia, 316

gap junctions, 90, 180,

pulmonary hyper-

frontal lobe, 344, 348

190, 302

tension, 214

frostbite, 24

gasping, 82

tissue repair, 50f

fructose, 150, 244f, 292

gastrectomy, 38, 148ff

venous disease, 240

fructose intolerance,

gastric ulcers, see peptic

fight and flight reaction, 334

244f, 292

ulcers

filtration (see edema),

fructose-1,6-diphosphate

gastric acid, 134, 142ff

80, 102ff, 234ff

aldolase, 244

gastric inhibitory poly-

fistulas, 88

fructose-1-phosphate

peptide, 136, 292

fit3 ligand (FL), 28

aldolase, 244

gastric juice, 134ff, 140ff

Fitzgerald factor, 60

FSH (follicle stimulating

gastric reflux, 136, 140, 284

flaccid lung, 76ff

hormone), 260, 272ff

gastric rupture, 140

flatulence, 150, 154

functional dead space, 72

gastric ulcers, see peptic

Fletcher factor, 60

functional residual

ulcers

flickering light, 338

capacity, 74

gastrin, 142ff

flocculus, 316

fundoscopy, 212

calcium, 128

flow velocity, 178

fungi, CSF, 356

chronic renal failure, 112

fluordeoxyuridylate, 34

gastritis, 142

esophagus, 136ff

5-fluorouracil, 316

immune defense,

insulin release, 292

fluoxetine, 350

42, 48, 54, 58

signal transmission, 6

flush, 148, 294

Funny current, 180

gastrinoma, 146, 152

Fms (receptor), 14

 

gastrin-releasing pep-

foam cells, 236ff

G

tide, 144

folate, 30, 34

gastritis, 34, 38, 142ff, 152

atherosclerosis, 236

 

gastroesophageal reflux, 138

hemostasis, 64

G cells, 144

gastrointestinal infec-

hypothyroidism, 284

G proteins, 6f, 14, 226, 300

tions, 142ff, 150ff, 270

liver failure, 174

G protein receptor kinases,

gastrointestinal tract,

malabsorption, 154

354

134ff, 176

follicles, 274

G0/G1/G2 phase, 2

gastropathy, 142ff

follicle-stimulating hormone

GABA, addiction, 354

gastroscope, 142

(follitropin), 260, 272ff

antidiuretic hormone,

Gaucher’s disease, 244

foramen magnum, 358

260

genetic defects, amino acid

foramen ovale, 202

basal ganglia, 312

metabolism, 292

Foramina luschkae,

epilepsy, 338

androgens, 272

Magendii, 356

heme synthesis, 254

anemias, 36, 40

fg

ge

Index

379

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ge

gl

Index

380

cerebellum, 316

glomerular filtration rate

somatotropin, 262

cystic fibrosis, 162

see GFR

thyroid hormones, 282

hypoglycemia, 292

glomerular function, 102ff

glucose-6-phosphatase, 244

lipoproteins, 118, 247f

glomeruli, 78

glucose-6-phosphate dehy-

renal transport, 96ff

glomerulonephritis,

drogenase, 40

sceletal muscle, 306

102ff, 108

glucose-6-phosphate trans-

genetic disposition,

allergies, 54

locase, 244

addiction, 354

autoimmune diseases, 56

glucose-galatose mal-

Alzheimer’s disease, 348

diabetes mellitus, 290

absorption, 96

atherosclerosis, 236

hypertension, 210

α-glucosidase, 244

autoimmune diseases, 56

glossitis, 154

β-glucosidase, 164, 244

diabetes mellitus, 286

glossopharyngeal nerve, 330

glucuronyl transferase, 168

hypercholesterolemia,

glottis, 76, 294

glutamate, basal ganglia,

247

glucagon, autonomic

312ff

schizophrenia, 352

nervous system, 332

consciousness, 342

venous disease, 240

diabetes mellitus, 286

epilepsy, 338

genital tract, 162

insulin release, 292

kidney, 92, 96

germ cells, 2, 18

portal hypertension, 170

memory, 346

gestagens, see progesterone

signal transmission, 6

schizophrenia, 352

GFR, 94, 102ff

somatotropin, 262

stroke, 360

Addison’s disease, 270

tumors, 16

glutamate decarboxy-

aging, 18

β-glucocerebrosidase, 244

lase, 338

diabetes mellitus, 290

glucocorticoids, see cortisol

glutamate dehydrogen-

eicosanoids, 296

gluconeogenesis, alkalosis,

ase, 316

hepatorenal syndrome,

90

glutamate receptors, 18, 338,

118

glucocorticoids, 268ff

342, 346, 352

hyperthyroidism, 282

hormones, 258

glutamate decarbox-

magnesium, 126

hypoglycemia, 292

ylase, 286

pregnancy, 116

insulin, 288

glutamine, 86, 342

renal failure, 108ff

kidney, 92

glutathione, 40, 144, 172

salt balance, 122

somatotropin, 262

glycerol, 288

GFs, see growth factors

thyroid hormones, 282

glycerophesphoryl-

GH (growth hormone),

glucosaminoglycans, 4

choline, 110

see somatotropin

glucose, 244f, 288ff

glycine, 82, 94

Gi proteins, see G-proteins

coronary heart dis-

glycogen, 244f

giant-cell arteritis, 240

ease, 220

autonomic nervous

gigantism, 262, 276

CSF, 356

system, 332

Gilbert syndrome, 168

Cushing’s disease, 268

calcium, 128

GIP, see gastric inhibitory

depression, 350

female sex hormones, 276

polypeptid

diabetes mellitus,

insulin, 258, 288

Gitelman’s syndrome, 98

286ff, 324

thyroid hormones, 282ff

Glanzmann-Naegeli throm-

diarrhea, 150ff

glycogen storage diseases,

basthenia, 64

gastrectomy, 148

174, 242ff, 292

glaucoma, 322f

glycogen storage diseases,

glycolysis, 288ff

gliadin, 54

244

Addison’s disease, 270

glial cells, 356f

hyperoxia, 84

alkalosis, 90

Alzheimer’s disease, 348

insulin, 258, 286ff

thyroid hormones, 282

consciousness, 342

kidney, 92, 94ff, 100, 110

glycoproteins, 60ff,

hypothyroidism, 284

phosphate, 130

132, 172

immune defense, 44

potassium, 124

glycosamineglycan,

glial scars, 338

pregnancy, 116

50, 104, 284

globin, see hemoglobin

salt balance, 122

glycosuria, 96, 116, 126

globosus, 316

schizophrenia, 352

glycosylation, 290, 324

globus pallidus, 312

sensory system, 318

glycyrrhizinic acid, 212

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