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Файл:Ординатура / Хирургия / Библиотека им академика М.И. Перельмана / Книга_5430_Библиотеки_им_академика_М_И_Перельмана
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84
Metals in Medicine, Volume 2
inorganic (physicochemical traits attributable to their inorganic constituents,
such as metals or semiconductor materials) like metallic nanoparticles like
Due to their catalytic and antioxidant capabilities, metal oxide nanoparticles
include iron oxide (Fe
3
O
4
2
2
), ceria (CeO
2
), and
applications.
6,7
FIGURE 3.1
agent. Multidisciplinary teams comprising chemists, pharmacists, biologists,
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Zinc Oxide Nanoparticles in Disease Diagnosis
85
-
8
3.2 ZINC: AN ESSENTIAL ELEMENT
9,10
and humans in 1963. Much has been discovered during the past 40 years
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86
Metals in Medicine, Volume 2
-
not re-established, other metabolic adjustments occurs.
11
-
-
ments.
12
catalysis, energy , paints, textiles, cosmetics, paints, and the healthcare sector
(cancer therapy, drug delivery, gene delivery, antimicrobial application, bio
imaging, bio sensing, etc.).
13
structural support, and regulation. It actively takes part in the catalysis and
-
opment, membrane stability, behavioral response, reproduction, bone
14,15
compartments to carry out the numerous duties listed above, and there are
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Zinc Oxide Nanoparticles in Disease Diagnosis
87
16,17
FIGURE 3.2
In immunological responses, apoptosis, oxidative stress, homeostasis,
killer (NK) cell activity , and aging.
18
In the body , the skin has the third-largest
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88
Metals in Medicine, Volume 2
-
-
pathica.
19
20
diseases. An innovative idea that has been used in other illnesses is the use
21
per some studies.
22
23
-
ological relevance, biocompatibility, biodegradability, and pro-regeneration
-
covalent bonds predominate.
24
-
4
4
.2H
2
ZnFe
2
0
4
2
0
4
, and gahnite), carbonates (smithsonite, ZnC0
3
),
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Zinc Oxide Nanoparticles in Disease Diagnosis
89
phosphates (Zn
3
(P0
4
)
2
.4H
2
0, hopeite) and silicates (Zn
2
Si0
4
Zn
4
Si
2
0
7
(OH)
2
.H
2
9
TABLE 3.1
Compounds
of zinc
Formula Uses References
Zinc
gluconate
C
12
H
22
O
14
Zn •
•
25–27
Zinc
pyrithione
C
10
H
10
N
2
O
2
S
2
Zn
•
• -
28,29
Zinc
ricinoleate
C
36
H
66
O
6
Zn •
30
Zinc stearate C
36
H
70
O
4
Zn •
31
Zinc nitrate Zn(NO
3
)
2
• It is employed in the lab to create
coordination polymers, although it has
little practical usage on a broad scale.
32
• Used as oral supplementation to reduce
arthritis.
•
disease.
•
-
tered orally.
33-35
Zinc
phosphate
Zn
3
(PO
4
)
2
• Used as anticancer agent in breast cancer
therapy.
•
membranes can reduce irritation brought
on by membrane exposure and reduce
36,37
Zinc
molybdate
MoO
4
Zn • It is used as a corrosion inhibitor. 38
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Metals in Medicine, Volume 2
Compounds
of zinc
Formula Uses References
Zinc
chromate
ZnCrO
4
•
inhaled.
39
Zinc acetate Zn(C
2
H
3
O
2
)
2
•
ointment, a topical lotion, or in combina-
• It is used as adjunctive therapy in
disease.
40,41
ZnS
•
emitters, and electro catalytic.
42
Zinc cyanide Zn(CN)
2
• -
nine dyes.
43
Zinc
peroxide
H
2
O
2
Zn •
on by a micro aerophilic hemolytic
streptococcus.
• It has been used as a preventative measure
mucous membrane.
44,45
Zinc oxide ZnO
• Paints, creams, cosmetics, glass, cement,
photography, electrostatic copying paper,
-
turing, and as an ultraviolet absorber in
use it.
46
3.3 ZINC OXIDE NANOPARTICLES
TABLE 3.1 (Continued)
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Zinc Oxide Nanoparticles in Disease Diagnosis
91
-
characteristics. Zinc oxide (ZnO) has been designated by the US FDA as a
human toxicity.
47–50
-
becoming smaller particles at the nanoscale. On a small scale, this technique
molecules using chemical and physical techniques. It is more expedient and
51
Physical techniques comprise ball milling, laser ablation, etching, and
sputtering. Studies conducted by S. Wirunchit et al. used the ball milling
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Metals in Medicine, Volume 2
52
Another quick and
nm) submerged in NaOH (0.1 M).
53
54
-
55
FIGURE 3.3
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Zinc Oxide Nanoparticles in Disease Diagnosis
93
groups based on their physical state: liquid phase synthesis and gas phase
2
-
drate (Zn(CH
3
COO)
2
.2H
2
O) as the parent material to create ZnO nanopar-
56
K
2
CO
3
and Zn(NO3)
3
-
57
58
Gas phase synthesis comprises aerosol pyrolysis and gas condensation. One
electron microscopy (SEM) revealed that the produced nanoparticles had
59
Another
condensation to create ZnO nanoparticles.
60
-
61
-
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