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Файл:Ординатура / Хирургия / Библиотека им академика М.И. Перельмана / Книга_5430_Библиотеки_им_академика_М_И_Перельмана
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174
Metals in Medicine, Volume 2
6.1 INORGANIC NANOPARTICLES
-
1,2
Inorganic
nanoparticles such as Ag and Au NPs, magnetic nanoparticles, metal-oxide-
dots, nanorods, nanosheets, nanocomposites, and other structures gain
capabilities make them advanced materials, especially in sensor applica-
3
Nano-structured metal-oxide semiconductors had
potential in toxic gas and combustible gas sensor applications due to their
metal-oxide nanoparticles has a role in the optical, electrical, and thermal
2
nanoparticles have been
ammonia, carbon monoxide, and hydrogen gases because
small nanocomposites and SnO
2
Sampath et al.
4
into SnO
2
and decreasing band gap energy. Furthermore, the photocatalytic activity
untreated SnO
2
nanoparticles.
4
Magnetic nanoparticles (MNPs) have been
-
hyperthermia, magnetic imaging system, controlled drug release systems,
and sensor studies.
5
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ceramic nanosheets in packaging systems has been extensively investigated
-
0D and 1D nanocomposites. Moreover, it is possible to increase the barrier
6
-
-
specic characteristic
6.2 GREEN METHODOLOGIES OF Ag/Au NPs
uneven distribution. Chemical processes use both inorganic and organic
reducing agents. Compared to physical methods, they provide nanoparticle
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Metals in Medicine, Volume 2
components can exhibit toxic and corrosive properties. Due to global
-
synthesis using microorganisms as they do not require complex and special-
7
natural materials.
FIGURE 6.1
natural materials.
Ag NPs have properties that vary depending on pH and temperature.
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) to
Ag
0
phenols, proteins, and amino groups) contained in the plant extracts actively
8
Due to their excellent
characteristics such as optical, physical, electrical, morphology, chemical,
have other advantages, such as non-cytotoxicity and chemical inertness. In
-
Recently , microbial-based Ag and Au NPs have been investigated in various
et al.,
9
Pseu-
domonas indica
3
)
-
property against Mucor racemosus, Syncephalastrum racemosum, and
Rhizopus microsporus
9
Mistry et al.
10
Aspergillus brunneoviolaceus
-
−
10
11
used
Beauveria bassiana
study, Shunmugam et al.
12
Vibrio alginolyticus, marine bacterium,
-
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178
Metals in Medicine, Volume 2
50
lines, in conclusion.
12
It has been underlined that using plant extract-based methods rather than
With recent green trends, Ovas et al. investigated Conocarpus lancifolius
3
3
ions to Ag
0
3
precipi-
Rhizopus
stolonifer and Aspergillus avus
MDA MB-231 breast cancer cell lines.
13
In 2021, Sellami et al.
14
carried out
Olea europaea O. eur opaea
4
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method, these nanoparticles have cytotoxic potential against MCF-7 cancer
14
Natural sources
TABLE 6.1
Material Nanoparticles Size
Pseudomonas indica Ag NPs 2.3–53.5 nm
Aspergillus brunneoviolaceus Ag NPs 0.72 and 15.21 nm
Beauveria bassiana Ag NPs 10–50 nm
Vibrio alginolyticus Au NPs 100–150 nm
Conocarpus lancifolius Ag NPs 21–173 nm
Olea europaea Au NPs 40 nm
Pleurotus sajor-caju Au NPs-Ag NPs 15–20 nm
Pandanus canaranus Au NPs-Ag NPs 37.44 nm and 6.33–24.43 nm, respectively
Commiphora wightii Au NPs 20.2 nm
Waste banana stalks Au NPs-Ag NPs
37.44 nm and 6.33–24.43 nm,
respectively
6.3 SURFACE CHARACTERIZATION
interparticle interactions. For this purpose, various techniques, such as
-
X-ray photoelectron spectroscopy (XPS), scanning electron microscope
, and dynamic light scattering (DLS), have
nanosystems. For example, Abid et al.
15
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180
Metals in Medicine, Volume 2
-
15
In another study , Magogotya
et al.
16
polyethylene glycol (PEG)-liganded -carboxyl, -hydroxyl, and -amine Au
positively
-
16
In 2020, Chand et al.
17
2
NPs using Acacia catechu
-
17
Zhang et al.
18
-
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181
-
18
6.4 PROPERTIES OF Ag NPs AND Au NPs
-
examined.
19
-
uses in engineering, biotechnology , and especially medicine, considering the
20
applications in BiFeO
3
therapy.
21
22
polydispersity and homogeneous dispersion could be produced in a sodium
-
bial activity as compared to the tested microorganisms. For this reason, Au
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Metals in Medicine, Volume 2
22
In another study, Doan et
al.
23
strains demonstrated very robust bioactivity against the green Ag NPs. It
against Bacillus cereus (4.0 ppm) and Escherichia coli (E. coli) (2.0 ppm).
24
),
Ganoderma lucidum mushroom
detection and
-
4
-
including Staphylococcus aureus (S. aureus), Bacillus subtilis (B. subtilis),
Bacillus cereus (B. cereus), Escherichia coli (E. coli), and Pseudomonas
aeruginosa (P. aeruginosa). In ecological, toxicological, biomedical, and
over GL-Au NPs.
24
-
-
their antimicrobial properties. In biomedical applications, Ag NPs-based
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-
-
25
6.5 Ag AND Au NPs FOR DRUG DELIVERY SYSTEMS
kinetic models have been calculated to better understand drug release
26
phytocomponents, the green nanoparticles are extremely stable in aqueous
dispersions. According to the in vivo and in vitro experimental results, the
-
empirical observations.
26
In 2018, Jabir et al.
27
NPs had great potential in antimicrobial drug delivery systems.
27
Chaturyedi
et al.
28
Pleurotus sajor-caju
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