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Файл:Ординатура / Хирургия / Библиотека им академика М.И. Перельмана / Книга_953_Библиотеки_им_академика_М_И_Перельмана.pdf
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- •Dedication
- •Contributors
- •Foreword
- •Preface
- •Contents
- •Indications/Contraindications
- •Surgery
- •Conclusions
- •Complications
- •Results
- •Indications/Contraindications
- •Surgery
- •Technique
- •Complications
- •Results
- •Conclusions
- •Indications
- •Contraindications
- •Conclusions
- •Surgery
- •Complications
- •Results
- •Conclusions
- •Indications/Contraindications
- •Surgery
- •Complications
- •Results
- •Conclusions
- •Introduction
- •Indications/Contraindications
- •Surgery
- •Complications
- •Results
- •Conclusions
- •Acknowledgments
- •Indications/Contraindications
- •Surgery
- •Complications
- •Results
- •Conclusions
- •Indications/Contraindications
- •Surgery
- •Complications
- •Results
- •Conclusions
- •Indications/Contraindications
- •Surgery
- •Complications
- •Results
- •Conclusions
- •Indications/Contraindications
- •Surgery
- •Complications
- •Results
- •Conclusions
- •Indications/Contraindications
- •Surgery
- •Complications
- •Results
- •Conclusions
- •Introduction
- •Indications
- •Contraindications
- •Results
- •Indications/Contraindications
- •Surgery
- •Complications
- •Results
- •Conclusions
- •Introduction
- •Complications
- •Conclusions
- •Indications/Contraindications
- •Surgery
- •Complications
- •Results
- •Conclusions
- •Indications/Contraindications
- •Surgery
- •Complications
- •Results
- •Conclusions
- •Indications/Contraindications
- •Surgery
- •Complications
- •Results
- •Conclusions
- •Introduction
- •Indications/Contraindications
- •Surgery
- •Complications
- •Results
- •Conclusions
- •Acknowledgments
- •Introduction
- •Indications/Contraindications
- •Surgery
- •Conclusions
- •Complications
- •Results
- •Surgery
- •Complications
- •Results
- •Conclusions
- •Indications/Contraindications
- •Surgery
- •Complications
- •Conclusions
- •Introduction
- •Indications/Contraindications
- •Surgery
- •Complications
- •Results
- •Conclusions
- •Indications/Contraindications
- •Anatomy
- •Complications
- •Results
- •Conclusions
- •Indications/Contraindications
- •Surgery
- •Complications
- •Results
- •Conclusions
- •Introduction
- •Indications/Contraindications

POSTOPERATIVEMANAGEMENT
Patientsbeginsitzbathsontheeveningofthesurgery;ahigh-fiberdiet
and/orfibersupplementsarerecommendedtomaintainasoftandbulky
stool.Analgesicsareprovidedandpatientsareinformedthat
postoperativepaintypicallyresolveswithin1week.Patientsresume
activitiesastoleratedandareexpectedtoreturntonormalfunctions
within2weeks;fissurehealinggenerallyoccurswithin4weeks.

COMPLICATIONS
Abscess
Fistula-in-ano
Fecalincontinence
Recurrentandunhealedfissure
Alteredbowelfunctionandcontinencearenotunusualfollowingthe
surgeryandareaccentuatedwiththeuseofahigh-fiberdiet.Alterations
tocontrolaremorelikelytooccurwithflatusthanfeces(Table21-1).
Garcia-Aguilaretal.reported30%and12%lossofcontroltoflatusand
feces,respectively.Otherstudies(Table21-1)reportafarlower
percentageoflossofcontrol(0–9%).Impairmentofcontrolofflatus
(31%)andfeces(23%)andincreasedsoilinghavebeenreported.The
impairedcontrolistemporary.Thereisnoquestion,however,thatLISis
effective.Theoverallpercentageoffissurerecurrenceislow(0–5.6%)
exceptforonestudybyGarcia-Aguilarwhoreportedarecurrencerateof
10.9%.However,ofthosepatientswithrecurrenceonly3.4%requiredreoperation(Table17-1).
TABLE21-1 PatientOutcomesFollowingOpenLateralInternal
Sphincterotomy
Author Year
No.of
patients
Impaired
control
Fecal
soiling
(%)
Flatus
(%)
Feces
(%)
Abcarian 1980 Retrospective 150 0 0 0
Maryaetal. 1980 Retrospective 100 0 0 0
Ravikumaretal. 1982 Retrospective 60 0 0 5
Jensenetal. 1984 RCT 30 0 0 0
Frezzaetal. 1992 Retrospective 134 0 0 0
Leongetal. 1994 Retrospective 114 7.9 0 NR
PernikoffandSalvati 1994 Retrospective 500 2.8 0.4 4.4

RomanoGetal. 1994 Prospective 44 9 4.5 4.5
Neufeldetal. 1995 Retrospective 112 12.5
*
0.9 8.9
Ohetal. 1995 Retrospective 1313 1.5
*
1.5 0
Usatoffetal. 1995 Retrospective 98 7 1 11
Garcia-Aguilaretal. 1996 Retrospective 324 30 12 27
HananelandGordon 1997 Retrospective 265 0.4 0.4 0.4
NyamandPemberton 1999 Retrospective
†
487 31
*
23
*
39
*
Argovetal. 2000 Retrospective 2,108 1.5
*
0 1
Richardetal. 2000 RCT 38 0 0 0
CasillasandHull 2005 Retrospective
†
298 30 2.8 0
Arroyoetal. 2005 RCT 40 2.5 5 NR
Elsebaeetal. 2007 RCT 46+ 0 2.17 0
46++ 0 0 0
Mousavietal. 2009 RCT 29 0 0 0
Silerietal. 2010 Prospective 72 0 0 0
*
Impairedcontrolreportedastemporary.
†
Surveyofpreviouslyoperatedpatients.Responseratesvary.
+,traditionalLIS;++,“tailored”LIS;NR,notreported;RCT,randomizedcontroltrial.
Arandomizedcontrolledtrialcomparing“tailored”LISwithtraditional
LISshowsadecreasedriskofalterationincontrol.Thereisadecreased
rateoffecalincontinencewith“tailored”LIS.However,treatmentfailure
isslightlyhigher.
Persistentandrecurrentfissuresareinfrequent,anddependingon
clinicalfindings,mayrequireanadditionallimitedsphincterotomyon
thecontralateralsideoranadvancementflap.Inarecentstudy,therisk
ofredosphincterotomywasminorincontinenceinonly4%ofpatients
withanoverallhealingrateof98%.
AbscessformationisuncommonwithanopenLISbecauseany
collectionoffluidlikelydecompressesthroughthesurgicalincision.
Fistulaformationisalsouncommonandmaybeduetoincisionor
compromiseoftheanoderm.

CONCLUSIONS
OpenLISisasafesurgicaloptionforthetreatmentofanalfissures.Most
LISproceduresareperformedduetochronicsymptomsdespite
nonoperativemanagement,but,occasionally,anLISisnecessaryinthe
acutesettingofseverepain.

RECOMMENDEDREFERENCESAND
READINGS
AbcarianH.Surgicalcorrectionofchronicanalfissure:resultsoflateralinternalsphincterotomy
vs.fissurectomy–midlinesphincterotomy.DisColonRectum1980;23:31–6.
ArgovS,LevandovskyO.Openlateralsphincterotomyisstillthebesttreatmentforchronicanal
fissure.AmJSurg2000;179:201–2.
ArroyoA,PérezF,SerranoP,CandelaF,LacuevaJ,CalpenaR.Surgicalversuschemical
(botulinumtoxin)sphincterotomyforchronicanalfissure:long-termresultsofaprospective
randomizedclinicalandmanometricstudy.AmJSurg2005;189(4):429–34.
CasillasS,HullTL,ZutshiM,TrzcinskiR,BastJF,XuM.Incontinenceafteralateralinternal
sphincterotomy:areweunderestimatingit?DisColonRectum2005;48:1193–9.
EisenhammerS.Thesurgicalcorrectionofchronicinternalanal(sphincteric)contracture.SAfr
MedJ1951;25:486–9.
ElsebeeMM.Astudyoffecalincontinenceinpatientswithchronicanalfissure:prospective,
randomized,controlledtrialoftheextentofinternalanalsphincterdivisionduringlateral
sphincterotomy.WorldJSurg2007;31:2052–7.
FrezzaEE,SandeiF,LeoniG,BiralM.Conservativeandsurgicaltreatmentinacuteandchronic
analfissure.Astudyon308patients.IntJColorectalDis1992;7:188–91.
Garcia-AguilarJ,BelmonteC,WongWD,LowryAC,MadoffRD.Openvs.closedsphincterotomy
forchronicanalfissure:long-termresults.DisColonRectum1996;39:440–3.
p.163
p.164
GoligherJC,DuthieHL,NixonHH.SurgeryoftheAnus,RectumandColon.5thed.London:
BailliereTindall,1984.
GorfineSR.Treatmentofbenignanaldiseasewithtopicalnitroglycerin.DisColonRectum
1995;38:453–6;discussion6–7.
HananelN,GordonPH.Lateralinternalsphincterotomyforfissure-in-ano–revisited.DisColon
Rectum1997;40:597–602.
JensenSL,LundF,NielsenOV,TangeG.Lateralsubcutaneoussphincterotomyversusanal
dilatationinthetreatmentoffissureinanoinoutpatients:aprospectiverandomisedstudy.Br
MedJ(ClinResEd)1984;289:528–30.
JonasM,NealKR,AbercrombieJF,ScholefieldJH.Arandomizedtrialoforalvs.topical
diltiazemforchronicanalfissures.DisColonRectum2001;44:1074–8.
JostWH,SchimrigkK.Useofbotulinumtoxininanalfissure.DisColonRectum1993;36:974.
LeongAF,HusainMJ,Seow-ChoenF,GohHS.Performinginternalsphincterotomywithother
anorectalprocedures.DisColonRectum1994;37:1130–2.
LiangJ,ChurchJM.Lateralinternalsphincterotomyforsurgicallyrecurrentchronicanalfissure.
AmJSurg2015;210:715–9.

LittlejohnDR,NewsteadGL.Tailoredlateralsphincterotomyforanalfissure.DisColonRectum
1997;40:1439–42.
LockMR,ThomsonJP.Fissure-in-ano:theinitialmanagementandprognosis.BrJSurg
1977;64:355–8.
MaryaSK,MittalSS,SinglaS.Lateralsubcutaneousinternalsphincterotomyforacutefissurein
ano.BrJSurg1980;67:299.
MousaviSR,SharifiM,MehdikhahZ.Acomparisonbetweentheresultsoffissurectomyand
lateralinternalsphincterotomyinthesurgicalmanagementofchronicanalfissure.J
GastrointestSurg2009;13(7):1279–82.
NeufeldDM,ParanH,BendahanJ,FreundU.Outpatientsurgicaltreatmentofanalfissure.EurJ
Surg1995;161:435–8.
NyamDC,PembertonJH,IlstrupDM,RathDM.Long-termresultsofsurgeryforchronic
constipation.DisColonRectum1997;40:273–9.
OhC,DivinoCM,SteinhagenRM.Analfissure.20-yearexperience.DisColonRectum
1995;38:378–82.
PernikoffBJ,EisenstatTE,RubinRJ,OliverGC,SalvatiEP.Reappraisalofpartiallateralinternal
sphincterotomy.DisColonRectum1994;37:1291–5.
RavikumarTS,SridharS,RaoRN.Subcutaneouslateralinternalsphincterotomyforchronic
fissure-in-ano.DisColonRectum1982;25:798–801.
RichardCS,GregoireR,PlewesEA,etal.Internalsphincterotomyissuperiortotopical
nitroglycerininthetreatmentofchronicanalfissure:resultsofarandomized,controlledtrial
bytheCanadianColorectalSurgicalTrialsGroup.DisColonRectum2000;43:1048–57;
discussion57–8.
RomanoG,RotondanoG,SantangeloM,EsercizioL.Acriticalappraisalofpathogenesisand
morbidityofsurgicaltreatmentofchronicanalfissure.JAmCollSurg1994;178:600–4.
SileriP,StolfiVM,FranceschilliL,etal.Conservativeandsurgicaltreatmentofchronicanal
fissure:prospectivelongertermresults.JGastrointestSurg2010;14(5):773–80.
SultanAH,KammMA,NicholisRJ,BartramCI.Aprospectivestudyoftheextentofinternalanal
sphincterdivisionduringlateralsphincterotomy.DisColonRectum1994;37:1031–3.
UsatoffV,PolglaseAL.Thelongertermresultsofinternalanalsphincterotomyforanalfissure.
AustNZJSurg1995;65:576–8.

Chapter22
ClosedLateralInternal
Sphincterotomy
SeanJ.LangenfeldandJoshuaI.S.Bleier
INTRODUCTION
Lateralinternalsphincterotomy(LIS)isasafeandeffectivetechniquefor
thetreatmentofchronicanalfissures.AtraditionalopenLISinvolvesa
radialincisionovertheinternalanalsphincter(IAS)todividethemuscle
underdirectvisualization.TheclosedLIStechnique,alsoknownasa
subcutaneoussphincterotomy,hasbeenadvocatedasaless-invasive
approachwithequivalentratesoffissurehealing.

INDICATIONS/CONTRAINDICATIONS
Indications
ClosedLISforanalfissurehasthesameindicationsastheopen
technique.LISistypicallyperformedforchronicanalfissuresrefractory
tomaximummedicaltherapy,includingstoolsofteners,sitzbaths,
topicalvasodilatoryagents,andbotulinumtoxininjection.LISisalso
appropriateasaprimaryapproachforacuteanalfissureswhenthereis
severe,unrelentingpain.OnceLISischosen,thesurgeonshouldstill
addressthepatient’sunderlyingboweldysfunction,includingdiarrhea
and/orconstipation,toensureasuccessfulsurgery.
Contraindications
RelativecontraindicationstoclosedLISincludelow-pressurefissures,
preexistingfecalincontinence,uncontrolledbleedingdisorders,and
activeanorectalCrohn’sdisease.PatientswithpreviousLISshouldalso
beselectedcarefullytopreventunwantedchangesinlong-termfecal
continence.Patientswithimmunosuppressionand/oratypicalfissure
locationsshouldalsobeselectedcarefullytoensurethesurgeonhasthe
correctdiagnosis.

PREOPERATIVEPLANNING
Appropriatesurgicalcareofthepatientwithananalfissurebeginsinthe
officesetting,wherethesurgeonshouldperformathoroughhistoryand
physicalexamination.Thisincludesanin-depthreviewofthepatient’s
medications,medicalandsurgicalhistory,andlifestyleissuesthatmaybe
contributingtothecurrentpathology.Afissurecanusuallybeidentified
duringtheexternalexaminationandfissure-relatedpainmaylimitthe
patient’stoleranceofadetailedanorectalexamination.However,adigital
rectalexamination,anoscopy,andrigidproctoscopyshouldbeperformed
ifpossible,becauseitallowsforanassessmentofhypertonicity,andthe
exclusionofotheranorectalpathologyincludinginfectionand
inflammation.“Typical”analfissuresarefoundineithertheposterior
(mostcommon)oranterior(lesscommon)midline.Identificationof
“atypical”fissuresthatlieinlateralpositions,orhaveanatypical
appearanceshouldpromptworkupforalternativeetiologiessuchas
HumanImmunodeficiencyVirusandsexuallytransmitteddiseases,and
theunderlyingdiseaseprocessshouldbeidentifiedandtreated.
OncethedecisionhasbeenmadetoperformLISinthesettingofa
typicalfissure,thepatientshouldbeappropriatelyeducatedonwhatto
expectbeforeandafterthesurgery,andwhatstepsshouldbetakentoaid
inthehealingprocess.Formostanorectalsurgeries,apreoperative
enemacanbeself-administeredtoremovestoolsfromtheoperativefield
andimprovevisualization.However,patientswithananalfissureare
oftenintolerantofthis,anditcanbeomittedsafelywhennecessary.

SURGERY
Positioning
ClosedLIScanbeperformedsafelyinthepronejackknifeposition,dorsal
lithotomy,orleftlateraldecubituspositionwithequalefficacy,andthis
decisioncanbemadebasedonsurgeonpreference.Itistheauthor’s
preferencetousethelithotomypositionwithcandycanestirrupsbecause
itisoftenquickerandsubjectivelypreferredbytheanesthesiateam.
However,itshouldbenotedthatthepronejackknifepositionoffers
enhancedvisibilityandtheeasieruseofanassistant.
Technique
Locoregionalblock
Inspectionforotherconcomitantpathologies
Identificationoftheintersphinctericgroove
Insertionofalow-profilescalpelwithcarefuldivisionoftheIAS
Generalanesthesiaisoftenused,butitisalsosafetoinsteaduse
monitoredanesthesiacare(MAC).Theanusispreppedwithpovidoneiodineanddrapedinasterilefashion(Fig.22-1),andalocalanestheticis
usedtoperformalocoregionalblock,typicallywith30–40mlof0.25%
bupivacainewithepinephrine.WhenMACisused,initialinfiltrationwith
1%lidocainewithorwithoutepinephrineoffersaquickerandlesspainful
onsetoflocalanesthesia.
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