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Ординатура / Хирургия / Библиотека им академика М.И. Перельмана / Книга_953_Библиотеки_им_академика_М_И_Перельмана.pdf
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Vaginal/PerinealClosure
Oncethevaginalwallfibromuscularis(fascia)hasbeenreapproximated with2-0absorbablesutures,theperinealmusculature(bulbocavernosus andtransverseperinealmuscles)canbeapproximatedinthemidlineto addfurtherdepthtothefistularepair,asinaperineoplasty(Fig.11-8). Thevaginal/perinealskinislooselyapproximatedwith2-0absorbable sutures.Nodrainsaretypicallyneeded.Ifsignificantbleedingis encounteredduringthedissection,avaginalpackingmaybeplacedto provideexternalcompression.Ifthepatientcomplainsofcolickyperineal pain,spasmsoftheperinealmusculatureshouldbesuspectedandmuscle relaxants(likeFlexeril)canbeprescribed.
FIGURE11-8Aperineoplastyapproximatestheperineal
musculaturetoprovidefurthertissuemassalongtheRVF closuresite.
POSTOPERATIVEMANAGEMENT
Postoperatively,patientsareusuallydischargedhomeonthedayofthe surgerywithnarcoticanalgesics,stoolsofteners,andlaxatives.No postoperativeantibioticsareprescribed,unlessthepatientisunableto voidintherecoveryroomandaFoleycatheterisplacedfordischarge. Patientsareencouragedtofollowaclearliquiddietforthefirst2weeks— especiallyiftherectalwoundintraoperativelyis>1cm,followedbya high-fiberdietwithadequatewaterintake.Stoolsoftenersarestartedon postoperativeday1.Theyareencouragedtoengageinmodestphysical activitysuchaswalkingandlighthouseholddutiesbuttorefrainfrom sexualactivityfor6weeks.Sitzbaths,threetofourtimesdailyasneeded forcomfortandafterbowelmovements,maybesoothing.Clinicvisitsare scheduledin14daysand6weeksuntiltheperinealandrectalwoundsare healed.

COMPLICATIONS

Themostcommoncomplicationsassociatedwiththisprocedureare thoseassociatedwithanyanorectalsurgicalprocedure,urinaryretention, andlocalinfection.Theincidenceofabscessintherectovaginalseptum canbediminishedbyensuringthatthereisadequatedrainageofthe surgicalsite.Iftheperinealwounddoesnotappeartobehealingwellat thesecond-weekvisit,oranyevidenceofsurgicalsiteinfectionisnoted, sitzbathsshouldbefurtherencouraged,andoralantibioticsgivenasseen necessary.

RESULTS

TransperinealRVFclosurehasahighreportedsuccessrate.Depending onthetechniqueused,reportedsuccessratesrangefrom71%to78%for episioproctotomy-fistulotomy-layeredclosure,to70–100%fortransverse perinealincision-fistulaexcision-layeredclosure.ThepresenceofCrohn’s diseaseincreasesrecurrencerates,butrepeatrepaircanbeperformed oncethediseaseprocessisquiescent.Thereisonepublishedcaseseries utilizingatransperinealLIFTwithabioprostheticgraft(SurgisisES, CookSurgicalInc.,Bloomington,IN)torepairtheRVF.Therewerefive (19%)fistularecurrences,therecurrenceratebeinglowerinprimary repairs(8%)andhigher(29%)inthosewhohadfailedatleasttwo previousattempts.

CONCLUSIONS

ThetransperinealapproachforthemanagementofRVFsisaneffective techniquethatallowsforclearsurgicalsiteexposureandexcisionofthe entirefistulatract.Multilayerclosureoftherectovaginaldefectimproves surgicalsuccessrates,andabiologicgraftcanbeusedtoaugment connectivetissuenotedtobedeficientduringthesurgicalrepair.New techniquessuchasLIFTwithabioprostheticseemtoyieldresultsequal toifnotsuperiortoothermethodsofmanagementintheearly experience.
RECOMMENDEDREFERENCESAND READINGS
AkibaRT,RodriguesFG,DaSilvaG.Managementofcomplexperinealfistuladisease.ClinColon
RectalSurg2016;29:92–100. ChewSS,RiegerNA.Transperinealrepairofobsteric-relatedanovaginalfistula.AustNZObstet
Gynaecol2004;44:68–71.
DevesaJM,DevesaM,VelascoGR,etal.Benignrectovaginalfistulas:managementandresultsof
apersonalseries.TechColoproctol2007;11:128–34. EllisCN.Outcomesafterrepairofrectovaginalfistulasusingbioprosthetics.DisColonRectum
2008;51:1084–8. GoldaberKG,WendelPJ,McIntireDD,WendelGDJr.Postpartumperinealmorbidityafter
fourth-degreeperinealrepair.AmJObstetGynecol1993;168:489–93. GottgensKW,HeemskerkJ,vanGemertW,etal.Rectovaginalfistula:anewtechniqueand
preliminaryresultsusingcollagenmatrixbiomesh.TechColoproctol2014;18:817–23. MichelassiF,MelisM,RubinM,HurstRD.Surgicaltreatmentofanorectalcomplicationsin
Crohn’sdisease.Surgery2000;128:597–603. OakleySH,BrownHW,Yurteri-KaplanL,etal.Practicepatternsregardingmanagementof
rectovaginalfistulae:AmulticenterreviewfromtheFellows’PelvicResearchNetwork.Female
PelvicMedReconstrSurg2015;21:123–8. PetrouSP,JonesJ,ParraRO.Martiusflapharvestsite:patientself-perception.JUrol
2002;167:2098–9. PintoRA,PetersonTV,ShawkiS,DavilaGW,WexnerSD.Aretherepredictorsofoutcome
followingrectovaginalfistularepair?DisColonRectum2010;53:1240–7. PitelS,LefevreJH,ParcY,ChafaiN,ShieldsC,TiretE.Martiusadvancementflapforlow
rectovaginalfistula:short-andlong-termresults.ColorectalDis2011;13:e112–5. SheltonAA,WeltonML.Transperinealrepairofpersistentrectovaginalfistulasusinganacellular
cadavericdermalgraft(Alloderm).DisColonRectum2006;49:1454–7. WiskindAK,ThompsonJD.Transverseperinealrepairofrectovaginalfistulasinthelowervagina.
AmJObstetGynecol1992;22:694–9. YeeLF,BirnbaumEH,ReadTE,KodnerIJ,FleshmanJW.Useofendoanalultrasoundinpatients
withrectovaginalfistulas.DisColonRectum1999;42:1057–64. ZimmermanDD,GosselinkMP,BrielJW,SchoutenWR.Theoutcomeoftransanaladvancement
flaprepairisnotimprovedbyanadditionallabialfatflaptransposition.TechColoprocto
2002;6:37–42.
Chapter12
RectovaginalFistula: TransvaginalApproachwith BioprostheticMesh
H.DavidVargas

INTRODUCTION

Rectovaginalfistuladescribesacommunicationbetweentherectumand vaginaallowingforthepassageofflatusandstoolpervagina,whichcan
complexfistulas,includingtraumaticinjuryduringobstetricdeliveryor postsurgicalcomplications;violentorsexualtrauma;neoplasticdisease and/ortheirtreatmentwithradiation;ortheymayoccurdueto pathologicconditionssuchasinflammatoryboweldiseaseorinfections suchasanalcryptoglandularandBartholin’sgland.
Arectovaginalfistulagenerallyrequiressurgicalrepairforcorrection. Variousspecialtiesengageintherepairofthesedefects—generaland colorectalsurgeons,gynecologists,andurologists—leadingtomultiple approachesandtechniques.Techniquesdescribedincludetransanal, transvaginal,transperineal,andtransabdominalapproachesandoffera spectrumofrepairsvaryinginthemagnitudeandtheextentofoperative dissectionandattendantmorbidity.Mostcommonly,surgeonsuselocal repairsinvolvingflapcreationandlayeredrepair.Morecomplex proceduresutilizingrotationalflapssuchasMartiusorgraciloplastyare generallyofferedforrecurrentorcomplexfistulas.Finally,themost complexrepairsinvolverectalresection—rectalsleeveresectionwith advancementandanalanastomosis,orradicalresectioninvolving proctectomywithcoloanalanastomosis—playaroleinthetreatmentof recurrentandcomplexrectovaginalfistulas.
Theuseoffecaldiversionconsiderablyvariesthoughgenerally reservedforcomplexcases—recurrentfistulasafterlowanteriorresection
orilealpouchanalanastomosis,postirradiationfistulas,andinthe managementoffistulasassociatedwithCrohn’sdisease.Resultsof rectovaginalfistulasurgeryvaryconsiderably,andmostdistressingisthe realitythatsubsequentprimaryrepairsbecomeincreasinglylesslikelyto succeedwithrepeatedattempts.Forthisreason,interpositionoperations areusedinthissetting.Rigorousstudyofthisconditionandits managementremainlimitedbytheheterogeneityofcauses,varietyof anatomicdefects,andrelativerarityofthecondition.Thebestsurgical practicecontinuestobedifficulttodefine.
Transvaginalapproachtoinsertionofbiologicprostheticmeshasan optionforrepairofarectovaginalfistulawasreported2004byPyeetal. Theauthorssuccessfullyrepairedarecurrentfistulaandsuggestedthata bioprostheticmeshaugmentedtherepair.Thefollowingdiscussion describesthetechniquefortransvaginalapproachtomeshinsertionand theroleitmayofferinthemanagementofthischallengingand devastatingcondition.

INDICATIONS

Generally,thescientificliteraturedescribingthetechniqueof transvaginalapproachtobiologicmeshinterpositionrepairprimarily consistsofsmallsingleinstitutionalseriesandthereforethereader shouldbewillingtoacceptverygeneralstatementsregardingthe indicationforthistechnique.Theevidenceforthesuperiorityofone techniquecomparedwithanothersimplydoesnotexist,giventhe absenceofwell-designed,prospectivecomparativestudies.Thechosen operativeapproachreflectsmoreoftenthesurgeon’sspecialtytraining andfamiliaritywiththeanatomicdissection.Studiesinsupportofa transvaginalapproacharisefromthegynecologicspecialtyliterature, whereastransanalapproacheslikewiseoriginatefromstudiesbythe colorectalspecialty.Asacolorectalsurgeon,Iwouldofferthepotential followingadvantagesforatransvaginalapproach:inthecaseof recurrenceorpersistentfistulawhereinitialorprioroperationoccurred viaatransanalapproach,atransvaginaloperationofferssurgical dissectionintissuewithpotentiallylessscarringandfibrosis.Inaddition, thevaginaoffersalargerorificeimprovingexposurefordissection.On thecontrary,colorectalsurgeonsaregenerallylessfamiliarwiththe dissectionplanesfromatransvaginalapproach;thecomplexandrobust vascularsupplytothevaginalwallleadstonuisancebleeding;and whereasatransvaginalapproachprovidesabettervisualizationofthe vaginaldefectthelithotomypositioningrequiredmaylimittheexposure andrepairoftherectalmucosaldefect.
Therationaleforinsertionofbiologicmeshistwofold.First,the insertionofthemeshinterposedbetweenlayeredrepairoftherespective organsfurtherseparatesthemucosalrepairsactingasaphysicalbarrier. Interpositiongraftsoftissue,usuallymusclefromthebulbocavernosus (Martiusflap)orgracilis,areveryeffectiveinaugmentingrepair.The massoftissueactingasabarrierseparatesthemucosalrepairs.In addition,suchautologoustissuerotationgraftsprovidetheaddedbenefit ofwell-vascularizedtissuethatresistsinfectioninthecontaminatedfield ofafistula.
Biologicmeshdoesnotoffersuchsimilarmasseffectorvascularity vascularization,butthesegraftsareessentiallyunlimitedinsupplyand donotrequireharvestingofmuscleandcreatingseparatewoundsand thepotentialforpainandwoundmorbidity.Biologicgraftspossess collagenmatrix,glycoproteins,andglucosaminethatpromote neovascularization,cellrecruitment,andingrowthoftissue.Themesh matrixservesasa“scaffold”initiatingtheingrowthoftissue,whereasin mostcasesthegraftmaterialdegradesovertimeandultimately
undergoesabsorptionbythehosttissue.
Avarietyofmeshgraftshavebeenutilizedderivedfromhuman cadavericdermis,autologousbuccalmucosa,porcinedermis,porcine intestinalsubmucosa,porcinebladdersubmucosa,andcross-linked collagenmatrix.