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Файл:Ординатура / Хирургия / Библиотека им академика М.И. Перельмана / Книга_953_Библиотеки_им_академика_М_И_Перельмана.pdf
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- •Dedication
- •Contributors
- •Foreword
- •Preface
- •Contents
- •Indications/Contraindications
- •Surgery
- •Conclusions
- •Complications
- •Results
- •Indications/Contraindications
- •Surgery
- •Technique
- •Complications
- •Results
- •Conclusions
- •Indications
- •Contraindications
- •Conclusions
- •Surgery
- •Complications
- •Results
- •Conclusions
- •Indications/Contraindications
- •Surgery
- •Complications
- •Results
- •Conclusions
- •Introduction
- •Indications/Contraindications
- •Surgery
- •Complications
- •Results
- •Conclusions
- •Acknowledgments
- •Indications/Contraindications
- •Surgery
- •Complications
- •Results
- •Conclusions
- •Indications/Contraindications
- •Surgery
- •Complications
- •Results
- •Conclusions
- •Indications/Contraindications
- •Surgery
- •Complications
- •Results
- •Conclusions
- •Indications/Contraindications
- •Surgery
- •Complications
- •Results
- •Conclusions
- •Indications/Contraindications
- •Surgery
- •Complications
- •Results
- •Conclusions
- •Introduction
- •Indications
- •Contraindications
- •Results
- •Indications/Contraindications
- •Surgery
- •Complications
- •Results
- •Conclusions
- •Introduction
- •Complications
- •Conclusions
- •Indications/Contraindications
- •Surgery
- •Complications
- •Results
- •Conclusions
- •Indications/Contraindications
- •Surgery
- •Complications
- •Results
- •Conclusions
- •Indications/Contraindications
- •Surgery
- •Complications
- •Results
- •Conclusions
- •Introduction
- •Indications/Contraindications
- •Surgery
- •Complications
- •Results
- •Conclusions
- •Acknowledgments
- •Introduction
- •Indications/Contraindications
- •Surgery
- •Conclusions
- •Complications
- •Results
- •Surgery
- •Complications
- •Results
- •Conclusions
- •Indications/Contraindications
- •Surgery
- •Complications
- •Conclusions
- •Introduction
- •Indications/Contraindications
- •Surgery
- •Complications
- •Results
- •Conclusions
- •Indications/Contraindications
- •Anatomy
- •Complications
- •Results
- •Conclusions
- •Indications/Contraindications
- •Surgery
- •Complications
- •Results
- •Conclusions
- •Introduction
- •Indications/Contraindications

Vaginal/PerinealClosure
Oncethevaginalwallfibromuscularis(fascia)hasbeenreapproximated
with2-0absorbablesutures,theperinealmusculature(bulbocavernosus
andtransverseperinealmuscles)canbeapproximatedinthemidlineto
addfurtherdepthtothefistularepair,asinaperineoplasty(Fig.11-8).
Thevaginal/perinealskinislooselyapproximatedwith2-0absorbable
sutures.Nodrainsaretypicallyneeded.Ifsignificantbleedingis
encounteredduringthedissection,avaginalpackingmaybeplacedto
provideexternalcompression.Ifthepatientcomplainsofcolickyperineal
pain,spasmsoftheperinealmusculatureshouldbesuspectedandmuscle
relaxants(likeFlexeril)canbeprescribed.
FIGURE11-8Aperineoplastyapproximatestheperineal
musculaturetoprovidefurthertissuemassalongtheRVF
closuresite.

POSTOPERATIVEMANAGEMENT
Postoperatively,patientsareusuallydischargedhomeonthedayofthe
surgerywithnarcoticanalgesics,stoolsofteners,andlaxatives.No
postoperativeantibioticsareprescribed,unlessthepatientisunableto
voidintherecoveryroomandaFoleycatheterisplacedfordischarge.
Patientsareencouragedtofollowaclearliquiddietforthefirst2weeks—
especiallyiftherectalwoundintraoperativelyis>1cm,followedbya
high-fiberdietwithadequatewaterintake.Stoolsoftenersarestartedon
postoperativeday1.Theyareencouragedtoengageinmodestphysical
activitysuchaswalkingandlighthouseholddutiesbuttorefrainfrom
sexualactivityfor6weeks.Sitzbaths,threetofourtimesdailyasneeded
forcomfortandafterbowelmovements,maybesoothing.Clinicvisitsare
scheduledin14daysand6weeksuntiltheperinealandrectalwoundsare
healed.

COMPLICATIONS
Themostcommoncomplicationsassociatedwiththisprocedureare
thoseassociatedwithanyanorectalsurgicalprocedure,urinaryretention,
andlocalinfection.Theincidenceofabscessintherectovaginalseptum
canbediminishedbyensuringthatthereisadequatedrainageofthe
surgicalsite.Iftheperinealwounddoesnotappeartobehealingwellat
thesecond-weekvisit,oranyevidenceofsurgicalsiteinfectionisnoted,
sitzbathsshouldbefurtherencouraged,andoralantibioticsgivenasseen
necessary.

RESULTS
TransperinealRVFclosurehasahighreportedsuccessrate.Depending
onthetechniqueused,reportedsuccessratesrangefrom71%to78%for
episioproctotomy-fistulotomy-layeredclosure,to70–100%fortransverse
perinealincision-fistulaexcision-layeredclosure.ThepresenceofCrohn’s
diseaseincreasesrecurrencerates,butrepeatrepaircanbeperformed
oncethediseaseprocessisquiescent.Thereisonepublishedcaseseries
utilizingatransperinealLIFTwithabioprostheticgraft(SurgisisES,
CookSurgicalInc.,Bloomington,IN)torepairtheRVF.Therewerefive
(19%)fistularecurrences,therecurrenceratebeinglowerinprimary
repairs(8%)andhigher(29%)inthosewhohadfailedatleasttwo
previousattempts.

CONCLUSIONS
ThetransperinealapproachforthemanagementofRVFsisaneffective
techniquethatallowsforclearsurgicalsiteexposureandexcisionofthe
entirefistulatract.Multilayerclosureoftherectovaginaldefectimproves
surgicalsuccessrates,andabiologicgraftcanbeusedtoaugment
connectivetissuenotedtobedeficientduringthesurgicalrepair.New
techniquessuchasLIFTwithabioprostheticseemtoyieldresultsequal
toifnotsuperiortoothermethodsofmanagementintheearly
experience.

RECOMMENDEDREFERENCESAND
READINGS
AkibaRT,RodriguesFG,DaSilvaG.Managementofcomplexperinealfistuladisease.ClinColon
RectalSurg2016;29:92–100.
ChewSS,RiegerNA.Transperinealrepairofobsteric-relatedanovaginalfistula.AustNZObstet
Gynaecol2004;44:68–71.
DevesaJM,DevesaM,VelascoGR,etal.Benignrectovaginalfistulas:managementandresultsof
apersonalseries.TechColoproctol2007;11:128–34.
EllisCN.Outcomesafterrepairofrectovaginalfistulasusingbioprosthetics.DisColonRectum
2008;51:1084–8.
GoldaberKG,WendelPJ,McIntireDD,WendelGDJr.Postpartumperinealmorbidityafter
fourth-degreeperinealrepair.AmJObstetGynecol1993;168:489–93.
GottgensKW,HeemskerkJ,vanGemertW,etal.Rectovaginalfistula:anewtechniqueand
preliminaryresultsusingcollagenmatrixbiomesh.TechColoproctol2014;18:817–23.
MichelassiF,MelisM,RubinM,HurstRD.Surgicaltreatmentofanorectalcomplicationsin
Crohn’sdisease.Surgery2000;128:597–603.
OakleySH,BrownHW,Yurteri-KaplanL,etal.Practicepatternsregardingmanagementof
rectovaginalfistulae:AmulticenterreviewfromtheFellows’PelvicResearchNetwork.Female
PelvicMedReconstrSurg2015;21:123–8.
PetrouSP,JonesJ,ParraRO.Martiusflapharvestsite:patientself-perception.JUrol
2002;167:2098–9.
PintoRA,PetersonTV,ShawkiS,DavilaGW,WexnerSD.Aretherepredictorsofoutcome
followingrectovaginalfistularepair?DisColonRectum2010;53:1240–7.
PitelS,LefevreJH,ParcY,ChafaiN,ShieldsC,TiretE.Martiusadvancementflapforlow
rectovaginalfistula:short-andlong-termresults.ColorectalDis2011;13:e112–5.
SheltonAA,WeltonML.Transperinealrepairofpersistentrectovaginalfistulasusinganacellular
cadavericdermalgraft(Alloderm).DisColonRectum2006;49:1454–7.
WiskindAK,ThompsonJD.Transverseperinealrepairofrectovaginalfistulasinthelowervagina.
AmJObstetGynecol1992;22:694–9.
YeeLF,BirnbaumEH,ReadTE,KodnerIJ,FleshmanJW.Useofendoanalultrasoundinpatients
withrectovaginalfistulas.DisColonRectum1999;42:1057–64.
ZimmermanDD,GosselinkMP,BrielJW,SchoutenWR.Theoutcomeoftransanaladvancement
flaprepairisnotimprovedbyanadditionallabialfatflaptransposition.TechColoprocto
2002;6:37–42.

Chapter12
RectovaginalFistula:
TransvaginalApproachwith
BioprostheticMesh
H.DavidVargas
INTRODUCTION
Rectovaginalfistuladescribesacommunicationbetweentherectumand
vaginaallowingforthepassageofflatusandstoolpervagina,whichcan
complexfistulas,includingtraumaticinjuryduringobstetricdeliveryor
postsurgicalcomplications;violentorsexualtrauma;neoplasticdisease
and/ortheirtreatmentwithradiation;ortheymayoccurdueto
pathologicconditionssuchasinflammatoryboweldiseaseorinfections
suchasanalcryptoglandularandBartholin’sgland.
Arectovaginalfistulagenerallyrequiressurgicalrepairforcorrection.
Variousspecialtiesengageintherepairofthesedefects—generaland
colorectalsurgeons,gynecologists,andurologists—leadingtomultiple
approachesandtechniques.Techniquesdescribedincludetransanal,
transvaginal,transperineal,andtransabdominalapproachesandoffera
spectrumofrepairsvaryinginthemagnitudeandtheextentofoperative
dissectionandattendantmorbidity.Mostcommonly,surgeonsuselocal
repairsinvolvingflapcreationandlayeredrepair.Morecomplex
proceduresutilizingrotationalflapssuchasMartiusorgraciloplastyare
generallyofferedforrecurrentorcomplexfistulas.Finally,themost
complexrepairsinvolverectalresection—rectalsleeveresectionwith
advancementandanalanastomosis,orradicalresectioninvolving
proctectomywithcoloanalanastomosis—playaroleinthetreatmentof
recurrentandcomplexrectovaginalfistulas.
Theuseoffecaldiversionconsiderablyvariesthoughgenerally
reservedforcomplexcases—recurrentfistulasafterlowanteriorresection

orilealpouchanalanastomosis,postirradiationfistulas,andinthe
managementoffistulasassociatedwithCrohn’sdisease.Resultsof
rectovaginalfistulasurgeryvaryconsiderably,andmostdistressingisthe
realitythatsubsequentprimaryrepairsbecomeincreasinglylesslikelyto
succeedwithrepeatedattempts.Forthisreason,interpositionoperations
areusedinthissetting.Rigorousstudyofthisconditionandits
managementremainlimitedbytheheterogeneityofcauses,varietyof
anatomicdefects,andrelativerarityofthecondition.Thebestsurgical
practicecontinuestobedifficulttodefine.
Transvaginalapproachtoinsertionofbiologicprostheticmeshasan
optionforrepairofarectovaginalfistulawasreported2004byPyeetal.
Theauthorssuccessfullyrepairedarecurrentfistulaandsuggestedthata
bioprostheticmeshaugmentedtherepair.Thefollowingdiscussion
describesthetechniquefortransvaginalapproachtomeshinsertionand
theroleitmayofferinthemanagementofthischallengingand
devastatingcondition.

INDICATIONS
Generally,thescientificliteraturedescribingthetechniqueof
transvaginalapproachtobiologicmeshinterpositionrepairprimarily
consistsofsmallsingleinstitutionalseriesandthereforethereader
shouldbewillingtoacceptverygeneralstatementsregardingthe
indicationforthistechnique.Theevidenceforthesuperiorityofone
techniquecomparedwithanothersimplydoesnotexist,giventhe
absenceofwell-designed,prospectivecomparativestudies.Thechosen
operativeapproachreflectsmoreoftenthesurgeon’sspecialtytraining
andfamiliaritywiththeanatomicdissection.Studiesinsupportofa
transvaginalapproacharisefromthegynecologicspecialtyliterature,
whereastransanalapproacheslikewiseoriginatefromstudiesbythe
colorectalspecialty.Asacolorectalsurgeon,Iwouldofferthepotential
followingadvantagesforatransvaginalapproach:inthecaseof
recurrenceorpersistentfistulawhereinitialorprioroperationoccurred
viaatransanalapproach,atransvaginaloperationofferssurgical
dissectionintissuewithpotentiallylessscarringandfibrosis.Inaddition,
thevaginaoffersalargerorificeimprovingexposurefordissection.On
thecontrary,colorectalsurgeonsaregenerallylessfamiliarwiththe
dissectionplanesfromatransvaginalapproach;thecomplexandrobust
vascularsupplytothevaginalwallleadstonuisancebleeding;and
whereasatransvaginalapproachprovidesabettervisualizationofthe
vaginaldefectthelithotomypositioningrequiredmaylimittheexposure
andrepairoftherectalmucosaldefect.
Therationaleforinsertionofbiologicmeshistwofold.First,the
insertionofthemeshinterposedbetweenlayeredrepairoftherespective
organsfurtherseparatesthemucosalrepairsactingasaphysicalbarrier.
Interpositiongraftsoftissue,usuallymusclefromthebulbocavernosus
(Martiusflap)orgracilis,areveryeffectiveinaugmentingrepair.The
massoftissueactingasabarrierseparatesthemucosalrepairs.In
addition,suchautologoustissuerotationgraftsprovidetheaddedbenefit
ofwell-vascularizedtissuethatresistsinfectioninthecontaminatedfield
ofafistula.
Biologicmeshdoesnotoffersuchsimilarmasseffectorvascularity
vascularization,butthesegraftsareessentiallyunlimitedinsupplyand
donotrequireharvestingofmuscleandcreatingseparatewoundsand
thepotentialforpainandwoundmorbidity.Biologicgraftspossess
collagenmatrix,glycoproteins,andglucosaminethatpromote
neovascularization,cellrecruitment,andingrowthoftissue.Themesh
matrixservesasa“scaffold”initiatingtheingrowthoftissue,whereasin
mostcasesthegraftmaterialdegradesovertimeandultimately

undergoesabsorptionbythehosttissue.
Avarietyofmeshgraftshavebeenutilizedderivedfromhuman
cadavericdermis,autologousbuccalmucosa,porcinedermis,porcine
intestinalsubmucosa,porcinebladdersubmucosa,andcross-linked
collagenmatrix.
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