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Ординатура / Хирургия / Библиотека им академика М.И. Перельмана / Книга_953_Библиотеки_им_академика_М_И_Перельмана.pdf
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Theauthorsprefertousea3–5×2–4cmdiamond-shapedislandflap comprisingfullthicknessskinandsubcutaneousfat.Theflapoutlineis firstmarkedonthenonscarredbuttockskin(Figs.6-9and6-10AandB). Theflapiselevatedusingdiathermy,aimingtoensurethattheedges slopeoutlaterallyinthesubcutaneoustissuetogiveabroaderbase;this actionreducestheriskoftheflapbeingdevascularized,whenitis advancedintotheanalcanal.
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FIGURE6-9Probeinfistulatract(schematic).
FIGURE6-10Incisionfordiamond-shapedanocutaneous
advancementflap:(A)actualviewand(B)schematic.
Theinternalopeningofthefistulaisexcised,includingasmallamount oftheinternalsphinctersurroundingtheinternalopening,butthedistal sphincterisnotdivided.Theinternalopeningisclosedwitha longitudinallineofinterruptedabsorbablemonofilamentsutures.The
externalcomponentofthetract,extendingfromtheexternalopeningto theexternalsphincter,isalsoexcised.Thescartissuebetweenthe internalandtheexternalopeningsisalsoroutinelyincised,andif feasible,excised;or,alternatively,curetted.
Itisveryimportanttodisconnecttheleadingedgeoftheflapfromthe subcutaneoustissuesattachedtothesphinctertogivemobility.Oncethe flapismobile,itisadvancedintotheanalcanal(Figs.6-11AandB)and usedtocovertheinternalopening.Itisusuallynecessarytorotatethe flapfromthecontralateralsidetocoveramidlinedefectbecauseof ipsilateralscarring.Theflapissuturedinsituusinginterrupted2/0–3/0 absorbablebraidedsutures(polyglactin)(Fig.6-12AandB).Thebuttock defect,outsidetheadvancedflap,isalsoclosedusing2/0braided absorbablesuturesinalinearfashion.Braidedabsorbablesuturesare usedforpatients’comfort.
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FIGURE6-11Flapbeingadvancedtocovertheinternal
opening:(A)actualviewand(B)schematic.
FIGURE6-12Suturedanocutaneousadvancementflap:
(A)actualviewand(B)schematic.
Asmalldrain,suchasasmalldePezzerormushroomtipcatheter,is placedintolargertractsviatheexternalopening.
Note:OthersprefertouseabroadbasedU-shapedinverted
anocutaneousflap.Theapexoftheflapshouldbe2–2.5cminwidthand sitedjustproximaltotheinternalopening.Itismarkedoutsothatthe baseisapproximatelytwicethewidthoftheapex.Thebasecanbe releasedfrom(asahouseflap)orleftattachedtothebuttockasa “tongue.”Proximally,theflapshouldencompassthesuperficialfibersof thelowerinternalsphincter.Thelengthshouldbesuchthatitallowsa tension-freeclosure.Thedistalpartoftheflapwillincludetheskinand subcutaneousfatoftheperianalregion.Furtheradvancementcanbe gained,ifrequired,byexcisingBurrow’strianglesofskinfromthe adjacentbase.Adisadvantageoftheseflapsisthattheyhavelimited lengthofmobilitywhencomparedwiththeislandflapsthatcanbe mobilizedabovetheanorectaljunctionwhenneeded,forexample, followingafailedrectaladvancementflapforarecurrent suprasphinctericfistula.
Theuseofalocalanestheticisavoidedinflaprepairstohelpprevent flapedemaand/orischemia.Temporarydivertingstomasareonly fashionedifthepatienthascomplexunresolvedsepsisortherehavebeen multiplepreviousattemptsatrepair.
POSTOPERATIVEMANAGEMENT
Oralanalgesicsusuallysufficewiththeendorectaladvancementflapas postoperativediscomfortisminimal,becausethereisnoperinealwound. Patientsareadvisedtoshowergently.Sitzbathsareavoided,particularly ifananocutaneousflaphasbeenraised,topreventtheflapdonorsite becomingmacerated.Thewoundshouldbedriedthoroughlyusinga hairdryerandadrydressingisappliedonlytoseparatethebuttocks.The patientcanhaveanormaldietbutstoolsoftenersaregiven.Low-dose metronidazoleiscontinuedinthepostoperativeperiodfor5days.
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Thepatientsarereviewedinthesurgeon’soffice4–6weeks postdischarge.Theyareadvisedtoavoidvigorousexerciseduringthis period.Patientsarealsoadvisednottobeconcernedifthereisapartial dehiscenceoftheflapdonorsitewound(thiscanoccurinupto50%of thepatients).Onanaverage,ittakesabout6weeksfortheperineal woundtohealcompletely.Inourexperience,patientstendtocheckthe appearancewithamirrorregularlyandneedreassuranceaboutthe appearance,particularlyduringthefirstcoupleofweeks.

COMPLICATIONS

Specifictothefistularepair,thecomplicationsinclude:
failure/recurrence.Itisimportanttoreevaluatepatientstoassessthe outcomeassuccessratesdecreasewithtime.Recurrenceappearstobe
causedbothbyfailureofthetreatmentandbyrecurrentpatientdisease flapbreakdown
sphinctercompromiseandincontinence(attributedtooverstretchingof theanalsphinctersbytheself-retainingretractor,disruptionofthe
sphinctercomplexbyinclusionoftheinternalsphincterfibers,and sensorydisruptionwithadvancementofrectalmucosadistally)
anorectalsepsis hematomaformation iatrogenicfistulaformation,includingrectovaginalfistulaewithanterior
flaprepairs ectropion(MAFs)

RESULTS

Successratesrelatingtothedifferenttypesoffistularepairvarywidelyin thepublishedliterature.Therehavebeenfewrandomizedcontrolled trials(RCTs)andmostofthestudiesofthetreatmentofanalfistulaeare smallandheterogeneouswithrespecttothetypeoffistulaincluded,the surgicaltechnique,andthelengthofthefollow-up,makingcomparison difficult.
SimpleAppositionalClosure
Theliteratureincludesonlyafewstudiesreportingexcisionandclosure oftheinternalopeningalone,withouttheuseofaflapprocedure.In 2004,ThomsonandFowlerreportedtheirexperiencewith44patientsof directappositionalclosureoftheinternalopeningwithouttheuseofa flap.Twenty-sixfistulaein28patientsappearedhealedat2–5months; withlongerfollow-ups,therepairfailedin41%ofthepatients. Athanasiadisetal.usingathree-layeredclosure,reportedaseriesof90 patientshavingatotalof106operations,andafollow-uptimeofbetween 6monthsand6years(median2.6years).Theriskofrecurrencewas18% (19fistulae),withthepredominantcauseoffailurebeingsutureline dehiscence.Followingrepair,94%ofthepatientswerecontinentand6% sufferedminimaldisorderedcontinence.
Transanal/EndorectalAdvancementFlaps
Awiderangeofsuccesswiththistypeofflaphasbeenreportedinthe literature,rangingfrom37%to93%.Morerecentstudieswithlarger patientnumbersandlongerfollow-upssuggestthatsuccessisgenerally intheorderof60–70%.Alargesingle-surgeonexperiencefromthe ClevelandClinic,Ohioreportedtheresultsofrectaladvancementflap repairsin75patients,31ofwhomsufferedCrohn’sdisease.Theywere followedupforameanof7±3years,andprimaryhealingoccurredin 72%ofpatients.Functionalresultsfollowingtheendorectaladvancement flaprepairappeargood,althoughmildtomoderateincontinencehas beenreportedinupto7–38%,associatedwithadecreaseinbothresting andsqueezepressuresonpostoperativemanometry.
Higherrecurrenceratesfollowingendoanaladvancementflapsare associatedwithundrainedsepsis,Crohn’sdisease,rectovaginalfistulae, andpriorrepair;inaddition,thesuccessratedecreaseswithtime.An RCTcomparingMAFwithfull-thicknessflapshasshownalowerrateof recurrencewiththelatter(40%comparedwith10%;P<0.05).
Variousstudieshaveinvestigatedwhetheraflaprepairincombination withanothertechnique(includingfibringlue,bioprostheticfistulaplug, orLIFTprocedure)isbetterthanaflaprepairalone,withmixedresults.
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FewRCTshavebeenperformedcomparingsurgicaltechniques.A meta-analysisofthreeRCTscomparingMAFwithafistulaplug,failedto showanadvantageofeithertechniqueorasignificantdifferencein complicationrate,pre-andpostoperativecontinencelevelsorqualityof life.OnesmallRCTcomparingMAFwiththeLIFTprocedurefailedto showasignificantdifferenceinrecurrenceorpre-andpostoperative continencelevels,althoughtheLIFTprocedurewasassociatedwitha highersatisfactionrate,lowerpostoperativepainandshortertimeto resumingnormalactivities.
AnocutaneousAdvancementFlaps
Theauthorspublishedtheirresultsusingthistechniquein16patients withcomplex,recurrent,orchronicsuprasphinctericfistulaein2005. Afterameanperiodoffollow-upof20(range1.5–43)months,complete healingwasseenin15(94%)patients.Atemporarydefunctioningstoma wasformedintwopatients.Only11patients(almost70%)reported improvedincontinence,2patientsreportednochangeintheirlevelof incontinence,and3patients(19%)reportedworseincontinence.
Otherpublishedstudiesreportcompletehealingratesof46–100%in non-inflammatoryboweldisease(IBD)patients.Oneofthelargest studiesbyNelsonetal.includedpatientswithbothIBDandnon–IBD­relatedfistulatracts.Seventy-threedermalislandflapsusingateardrop incisionwereperformedin65patients.Theyreportedapatientfailure rateof20%andaprocedurefailurerateof23%afterameanfollow-upof
28.4(range4–63)months.

CONCLUSIONS

Despitefamiliaritywithtechniqueandexpertise,allcolorectalsurgeons areawareofthechallengescomplexfistuladiseaseposeandthe frustrationoffailureandrecurrence.Nottheleast,otherwisehealthy youngpatientswithcomplexfistulaefindthediseasefrustratingand oftendifficulttocomprehendintermsoftheneedforstagedrepairsand potentialneedformultipleprocedures.Goodresultsaredependentonan understandingoftheanatomyofthepathologicalcondition,controlof sepsispriortoaflaprepair,andattentiontodetailtoensureatension­free,well-vascularizedflap.

ACKNOWLEDGMENTS

TheauthorswouldliketothankProfessorA.Eyersforhiskind permissiontousehisEndorectalAdvancementFlapvideointhis publication.
RECOMMENDEDREFERENCESAND READINGS
AthanasiadisS,HelmesC,YazigiR,KöhlerA.Thedirectclosureoftheinternalfistulaopening
withoutadvancementflapfortranssphinctericfistulas-in-ano.DisColonRectum
2004;47:1174–80. DeGroofEJ,CabralVN,BuskensCJ,etal.Systematicreviewofevidenceandconsensuson
perianalfistula:ananalysisofnationalandinternationalguidelines.ColorectalDis
2016;18:O119–34. EltingAW.Thetreatmentoffistula-in-ano.AnnSurg1912;56:744–52. GolubRW,WiseWEJr,KernerBA,KhandujaKS,AguilarPS.Endorectalmucosaladvancement
flap:thepreferredmethodforcomplexcryptoglandularfistula-in-ano.JGastrointestSurg
1997;1:487–91. GottgensKW,SmeetsRR,StassenLP,etal.Systematicreviewandmeta-analysisofsurgical
interventionsforhighcryptoglandularperianalfistula.IntJColorectalDis2015;30:583–93. HossackT,SolomonMJ,YoungJM.Ano-cutaneousflaprepairforcomplexandrecurrentsupra-
sphinctericanalfistula.ColorectalDis2005;7:187–92. JarrarA,ChurchJ.Advancementflaprepair:agoodoptionforcomplexAnorectalFistulas.Dis
ColonRectum2011;54:1537–41. LairdDR.Proceduresusedinthetreatmentofcomplicatedfistulas.AmJSurg1948;76:701–8. NelsonRL,CintronJ,AbcarianH.Dermalisland-flapanoplastyfortranssphinctericfistula-in-
ano:assessmentoftreatmentfailures.DisColonRectum2000;43:681–4. RickardMJ.Analabscessesandfistulas.ANZJSurg2005;75:64–72. RiegerN,TjandraJ,SolomonM.Endoanalandendorectalultrasound:applicationsincolorectal
surgery.ANZJSurg2004;74:671–5. SteeleSR,KumarR,FeingoldDL,etal.Practiceparametersforthemanagementofperianal
abscessandfistula-in-ano.DisColonRectum2011;54:1465–74. ThomsonWH,FowlerAL.Directappositional(noflap)closureofdeepanalfistula.ColorectalDis
2004;6:32–6. WilliamsJG,FarrandsPA,WilliamsAB,etal.Thetreatmentofanalfistula:ACPGBIposition
statement.ColorectalDis2007;9(4):18–50. WongS,SolomonM,CroweP,OoiK.Cure,continenceandqualityoflifeaftertreatmentfor
fistula-in-ano.ANZJSurg2008;78:675–82.