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Ординатура / Хирургия / Библиотека им академика М.И. Перельмана / Книга_3585_Библиотеки_им_академика_М_И_Перельмана

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4.4 Stenting Strategy andProcedure
231
4.4.5.2 Practical Culotte Stenting
Additional stenting with KBI is all that is required to accom­plish culotte stenting. When performing two stenting of the LM bifurcation, the aim is to completely eliminate SB jailing by the rst stent. Note that to completely eliminate SB jail­ing, rewiring of the SB should be performed through the most distal cell at the carina and then KBI should be repeated.
If the LM has a large diameter and if a Nobori 3.5-mm JV
stent has been implanted in the LAD, you should also implant a Nobori 3.5-mm JV stent in the LCX. If the LCX diam­eter is <3.5mm, the stent should be deployed by inating the SDB at a low pressure such as 4 to 5atm. Subsequently, high-pressure post-dilatation should be performed with a balloon of the optimal size. When provisional culotte stent­ing is performed, it is ideal to limit protrusion of the SB stent to a distance of 6 to 8mm into the MB (LM) lumen so as to minimize overlap between the two stents in the proximal MB (LM). You should position the POT balloon accurately to ensure safe and effective POT.If the POT balloon position is too proximal, it will have little effect when inated, while the balloon may over-dilate and damage the ostium of the distal MB if its position is too distal.
As stated above, it is difcult to accurately position the
POT balloon at the LM bifurcation with extreme angulation of the LAD or LCX. You do not need to worry about the distance for which the two stents appear to overlap. The most important objective of performing POT is to reliably achieve dilation of at least the proximal part of the LM in order to stabilize the stent prior to KBI.
Similar procedures apply to T stenting, except that the
kissing balloons may be inated at slightly higher pressures after two stenting. When KBI is done in the LMT, there is no problem with the proximal ends of the kissing balloons protruding into the sinus of Valsalva. To prevent distal dis­section, the two kissing balloons should be inated with their distal edges slightly proximal to the distal edges of the stents. High-pressure ination of two optimally sized kiss­ing balloons at the LM bifurcation is likely to cause dissec­tion. Therefore, I generally limit the maximum pressure to about 14atm when performing KBI.If a higher pressure is required, I try to inate balloons one quarter size smaller at pressures escalating from 20atm.
For two stenting, it is necessary to prepare the lesion suf-
ciently to eliminate the need for post-dilatation at very high pressures. Particularly if the LM is long, insufcient prepara­tion will lead to luminal irregularity of the rst stent, which may prevent advancement of a second stent through it. If the second stent is pushed forward forcibly when it becomes blocked, the stent often undergoes deformation and then is very difcult to advance further.
After implantation of the rst stent, POT has to be per­formed in the presence of a jailed guidewire and therefore should be done by inating the balloon at a relatively low pressure of about 14atm. If high-pressure ination is needed to sufciently dilate the proximal MB, high-pressure POT may be performed before KBI after SB wiring. It is likely that high-pressure POT will smooth out irregularities in the rst stent. If delivering the second stent into the SB is dif­cult, you should withdraw it and perform high-pressure POT along with relatively high-pressure KBI.This often facili­tates delivery of the stent into the SB.
The second stent may also be blocked by the carina, but this can be prevented if KBI is performed using a guidewire that crosses the rst stent into the LCX in contact with the carina. However, the second stent may sometimes be blocked by a “hard” carina. If this obstacle cannot be overcome by various efforts, you should remove the guidewire from the LAD and advance it into the LCX for use as a buddy wire. Then you should attempt to advance the second stent across the rst stent. If this also fails, you should advance a bal­loon along the buddy wire across the point where the stent is blocked while slightly and gently pulling the SDB back. If the second stent is then advanced gently, it can often be delivered successfully.
If this technique also fails, you should inate a balloon at 2 to 4atm in the LCX to trap the guidewire along which the stent will be delivered. Then you should advance the stent while pulling the guidewire back slightly. After the stent has been advanced, you can remove the buddy wire or advance it into the LAD.If even this procedure cannot overcome stent blockage, it is a good idea to use a GuideLiner catheter. You should advance this catheter gently with the tip of the bal­loon protruding from the tip of the catheter. To facilitate pas­sage of the catheter past the site of blockage, you should pull the preceding balloon back slightly. You should never apply strong force to the catheter. If this technique also fails, trap­ping the guidewire at a distal point by inating a balloon at a low pressure will facilitate steady advancement of the stent.
When upfront culotte stenting is planned, the proximal edge of either stent is always positioned in the LMT. It is preferable to implant the rst stent from the LMT to the LCX and the second stent from the LM ostium to the LAD, because this order of stenting will not induce indentations of the parts of the stents in the LM or LAD (Fig.4.24).
Even if LAD stenting precedes LM-LCX stenting, plac­ing the proximal edge of the stent in the LMT and covering the LM ostium with the second sent deployed in the LCX will avoid indentation of the stent in the LM.While inverse indentation may occur at the LAD ostium in this situation, the extent of indentation is usually acceptable.
232
ac
4 Stenting ofLeft Main Coronary Artery (LM) Lesions
bd
Fig. 4.24 Planned upfront culotte stenting. (a) When implanting the
rst stent in the LCX, protrusion of the proximal stent edge into the LM lumen should be limited to a distance of about 3mm. (b) After initial
4.4.6 T Stenting
POT and KBI. (c) After implanting the second stent from the LM to the LAD. (d) After repeat POT and KBI
that for accurately placing the proximal edge of a stent at the LM ostium. When stenting the SB, you should advance
T stenting of the LM bifurcation may be performed if the LCX has a take-off angle of nearly 90 degrees and particu­larly if there is a marked difference in diameter between the LAD and LCX (LAD > LCX). Under these circumstances, the struts of the stent implanted in the SB will not lose their radial strength (Fig.4.25). You should implant the SB stent so that its proximal edge protrudes slightly into the MB lumen. IVUS guidance may assist with accurate positioning of the stent. The method of stent positioning is similar to
the IVUS probe along the guidewire inserted into the LAD and should conrm that the proximal edge of the stent is just at the LCX ostium. Since the SB stent will never cross over the LAD ostium, there is no need to remove the IVUS probe when inating the SDB.If it is left in the LM/LAD, the IVUS probe will not interfere with advancement of the stent. Because of the large angle between the SB stent and the IVUS catheter, it is slightly difcult to visualize the prox­imal part of the stent by IVUS.
4.5 LM Trifurcation Stenting
233
4.5.1 Stenting with(Triple) KBI
After stenting the LAD, you should perform KBI to achieve complete stent apposition and dilate the bifurcation to its normal diameter, as stated previously. As with bifurcation stenting, two-link stents should be implanted and the kiss­ing balloons should be inated at a relatively low pressure (8–10atm) to avoid causing dissection/injury in non-stented segments of the SBs.
4.5.1.1 Lesion Preparation
You should follow the procedure recommended for bifur­cation KBI. The individual branches should be adequately prepared to ensure that sufcient dilation can be achieved by low-pressure balloon ination. The objectives of triple KBI are to reduce the risk of SB compromise by plaque shift or carina shift and to estimate the responsiveness of the distal LM bifurcation to low-pressure balloon angioplasty. When the LM bifurcation can be reliably expected to show low responsiveness, you should consider performing triple KBI with Lacrosse NSE balloons in order to optimize preparation of the trifurcation lesion.
Fig. 4.25 T stenting. T stenting may be performed at the LM bifurca-
tion if the SB (LCX) has a take-off angle of nearly 90 degrees and if the LCX has a small diameter
4.5 LM Trifurcation Stenting
Sometimes an additional artery arises at the bifurcation of the LM, forming a trifurcation. If this artery has a similar diameter to the LCX, it may be necessary to perform triple KBI and to implant stents in all three branches.
4.5.1.2 Stent Placement
After implanting a stent in the LAD, you should perform POT and then triple KBI according to the following proce­dure (Fig.4.26): (1) insert a new guidewire into the high lat­eral (HL) branch via the Crusade catheter; (2) perform KBI in the LAD and the HL branch; (3) insert a guidewire into the LCX via the Crusade catheter advanced along the HL guidewire; and (4) perform triple KBI.When wiring the SB, you should always pass the guidewire through the most distal cell at the carina.
234
4 Stenting ofLeft Main Coronary Artery (LM) Lesions
Branch 3
Branch 1
Branch 2
b
d
f
a
c
e
Fig. 4.26 Stent placement at the LM trifurcation. (a) Placing a stent in
Branch 1. (b) POT. (c). Rewiring Branch 2 with the aid of the Crusade catheter. (d) Performing KBI in Branches 1 and 2. (e) Rewiring Branch
4.5.2 Culotte Stenting attheLM Trifurcation
If lesions in the LAD and LCX are treated by culotte stent­ing, the HL branch will be compressed by both the LAD stent and the LCX stent, even if the culotte stenting is completed with triple KBI (Fig.4.27). In other words, there will be dual carina shift toward the HL branch. If dual carina shift is con­sidered to be approximately double that of a single carina, it is unlikely to be negligible, and persistent compression from dual carina shift may well increase the risk of restenosis at this branch.
Thus, a third stent needs to be implanted in the HL branch when treating LM trifurcation lesions because culotte stenting cannot prevent restenosis of the branch. An inter­ventionalist who aims to recanalize all three branches at a trifurcation lesion should choose trifurcation stenting rather than culotte stenting. However, LM trifurcation stenting has
3 with the aid of the Crusade catheter advanced along the Branch 2 guidewire. (f) Performing triple KBI
been reported to achieve very poor mid-term outcomes with regard to patency of the HL branch.
The proximal HL largely overlaps the proximal LAD/LCX on CAG.If the HL branch is stented last, its ostium may not be covered sufciently. Also, if triple KBI is only performed after stenting the HL branch following culotte stenting of the LAD/LCX, the guidewire inserted into the HL branch may bypass the culotte stents. On the other hand, if triple KBI is added to LAD stenting and to LCX stenting, trifurcation stenting will achieve full coverage of the three branches and ensure that all three stents obtain sufcient radial strength.
It is best to additionally perform triple KBI after HL stent­ing using the balloons maintained in the LAD and LCX.The stent in the HL branch should be positioned with its proximal edge protruding slightly into the LM lumen from the LAD­LCX carina (Fig. 4.28). IVUS can be used to conrm the position of the proximal edge of the stent.
a
4.5 LM Trifurcation Stenting
235
b
c
Fig. 4.27 Culotte stenting of various trifurcation lesions. (a) HL
branch arising from the LAD ostium. (b) HL branch arising between the LAD and the LCX. (c) HL branch arising from the LCX ostium
236
a
b
4 Stenting ofLeft Main Coronary Artery (LM) Lesions
c
Fig. 4.28 Placement of the third stent in the HL branch (c, d) after culotte stenting of the LAD/LCX (a, b). With the balloons maintained in the
LAD/LCX, HL stenting should be performed, followed by triple KBI
4.6 Case Study
d
Then I manipulated a guidewire via a Crusade catheter to insert it into the SB (LCX). Angiography showed that
This section provides an example of stenting an LM bifurca­tion lesion at my center.
To treat a true bifurcation lesion (Fig.4.29), I introduced a Judkins left short-tip guiding catheter (Launcher SL4) into the LM.
I performed pre-PCI IVUS to estimate the sizes of the tar­get vessels, as well as the characteristics and distribution of plaques. Attenuated plaque was found in the LAD, so I deliv­ered a Filtrap catheter to protect the distal LAD and then pre­dilated the LAD with a 3.0 mm balloon (Fig. 4.30a). After simultaneously inating 3.0mm and 3.5mm kissing balloons in the LAD and LCX (Fig.4.30b), I implanted a Nobori stent (3.5 × 24mm) from the LM to the LAD and expanded it at a relatively low pressure (Fig.4.30c). Subsequently, I performed POT by inating a 5.0mm balloon in the LM (Fig.4.30d).
the wire had failed to cross the stent through the most distal cell at the carina (Fig.4.31a), so I performed SB rewiring (Fig.4.31b).
After simultaneously inating 3.0mm and 3.5mm kiss­ing balloons in the LAD and LCX (Fig. 4.32), there was residual stenosis in the LCX.Therefore, I decided to switch to culotte stenting and implanted a Nobori 3.5-mm JV stent from the LM to the LCX with expansion at a relatively low pressure (Fig.4.33a). I then performed POT by inating a
5.0mm balloon in the LM (Fig.4.33b).
Next, wiring of the SB (LAD) was done via the Crusade catheter, and I conrmed by angiography that the wire crossed the stent through the most distal cell at the carina (Fig.4.34a). After KBI (Fig.4.34b), the bifurcation lesion was successfully recanalized (Fig.4.34c).
ab
ab
4.6 Case Study
Fig. 4.29 True LM bifurcation lesion
237
Fig. 4.30 KBI plus stenting of an LM bifurcation lesion. (a) POBA of
the LAD was done using a 3.0-mm balloon. (b) KBI was performed with 3.0-mm and 3.5-mm balloons in the LAD and LCX, respectively.
LAD : POBA (3.0×20 mm) KBI :
LAD 3.0 mm×LCX 3.5 mm
8 atm
(c) A Nobori 3.5-mm stent was deployed in the LAD at a relatively low pressure. (d) POT was performed by inating a 5.0-mm balloon in the LM
238
cd
Fig. 4.30 (continued)
4 Stenting ofLeft Main Coronary Artery (LM) Lesions
LAD : Nobori 3.5×24 mm
8 atm
LM : 5.0×10 mm
a
Fig. 4.31 SB (LCX) rewiring via a Crusade catheter. SB (LCX) rewir-
ing was done under angiographic guidance. (a) The guidewire inserted into the SB has not crossed the stent through the cell nearest to the
carina. (b) The SB guidewire now crosses the stent through the most distal cell at the carina
4.6 Case Study
b
Fig. 4.31 (continued)
239
KBI : LAD 3.0 mm×LCX 3.5mm 10 atm
Fig. 4.32 Simultaneous balloon ination in the LAD and LCX.A 3.0-mm balloon in the LAD and a 3.5-mm balloon in the LCX were inated
alternately at high pressure and then were inated simultaneously (KBI)
LCX : POBA (3.5×20 mm) 14 atm
LAD : POBA (3.0×20 mm) 14 atm
KBI : LAD 3.0 mm×LCX 3.5 mm 10 atm
240
ab
4 Stenting ofLeft Main Coronary Artery (LM) Lesions
LCX : Nobori 3.5×24 mm
10 atm
Fig. 4.33 Culotte stenting. After implanting a Nobori 3.5-mm stent in the LCX (a), POT was performed by inating a 5.0-mm balloon in the
LM (b)
LM : 5.0×10 mm
14 atm