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USMLE®

Step 2 CK

Lecture Notes

2021

Pediatrics

Published by dr-notes.com

USMLE® is a joint program of the Federation of State Medical Boards (FSMB) and the National Board of Medical Examiners (NBME), which neither sponsor nor endorse this product.

This publication is designed to provide accurate information in regard to the subject matter covered as of its publication date, with the understanding that knowledge and best practice constantly evolve. The publisher is not engaged in rendering medical, legal, accounting, or other professional service.

If medical or legal advice or other expert assistance is required, the services of a competent professional should be sought. This publication is not intended for use in clinical practice or the delivery of medical care. To the fullest extent of the law, neither the publisher nor the editors assume any liability for any injury and/or damage to persons or property arising out of or related to any use of the material contained in this book.

© 2020 by Kaplan, Inc.

Published by Kaplan Medical, a division of Kaplan, Inc. 750 Third Avenue

New York, NY 10017

All rights reserved. The text of this publication, or any part thereof, may not be reproduced in any manner whatsoever without written permission from the publisher.

10 9 8 7 6 5 4 3 2 1

Course ISBN: 978-1-5062-6147-8

Course Kit ISBN: 978-1-5062-6135-5

Retail ISBN: 978-1-5062-6145-4

Retail Kit ISBN: 978-1-5062-6137-9

Kit items come as a set and should not be broken out and sold separately.

Kaplan Publishing print books are available at special quantity discounts to use for sales promotions, employee premiums, or educational purposes. For more information or to purchase books, please call the Simon & Schuster special sales department at 866-506-1949.

Editors

William G. Cvetnic, MD, MBA

Fellow of the American Academy of Pediatrics

Board Certified in Pediatrics and Neonatal-Perinatal Medicine

Jacksonville, Florida

Eduardo Pino, MD

Associate Professor, Department of Pediatrics

Marshall University School of Medicine

Medical Director, Hoops Family Children’s Hospital

Cabell Huntington Hospital

Huntington, West Virginia

Published by dr-notes.com

We want to hear what you think. What do you like or not like about the Notes? Please email us at medfeedback@kaplan.com.

Table of Contents

00

Chapter Title

Chapter 1: The Newborn . . . . . . . . . . . . . . . . . . . . . . .

. . . . . . . . . . . . . . . . . . . .

. .

.

 

. . 1

Chapter 2: Genetics/Dysmorphology . . . . . . . . . . . . .

. . . . . . . . . . . . . . . . . . . .

. .

.

 

. 21

Chapter 3: Growth and Nutrition . . . . . . . . . . . . . . . .

. . . . . . . . . . . . . . . . . . . .

. .

.

 

. 31

Chapter 4: Development . . . . . . . . . . . . . . . . . . . . . . .

. . . . . . . . . . . . . . . . . . . .

. .

.

 

. 43

Chapter 5: Behavioral/Psychological Disorders . . . . .

. . . . . . . . . . . . . . . . . . . .

. .

.

 

. 49

Chapter 6: Immunizations . . . . . . . . . . . . . . . . . . . . . .

. . . . . . . . . . . . . . . . . . . .

. .

.

 

. 53

Chapter 7: Child Abuse and Neglect . . . . . . . . . .

. . . . . . . . . . . . . . . .

. .

 

.

.61. . . . . . .

Chapter 8: Respiratory

Disease . . . . . . . . . . .

. . . . . . . . . . . . . .

.

.

.

67. . . . . . . . . . . . .

Chapter 9: Allergy and

Asthma . . . . . . . . . . .

. . . . . . . . . . . . . .

.

.

.

81. . . . . . . . . . . . .

Chapter 10: Immune-Mediated Disease . . . . . . . . . . .

. . . . . . . . . . . . . . . . . . . .

. .

.

 

. 91

Chapter 11: Disorders of the Eye .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. ..

.. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. ..

.. ..

..

..

99

Chapter 12: Disorders of the Ear, Nose, and Throat .

. . . . . . . . . . . . . . . . . . . .

. .

.

105

Chapter 13: Cardiology

. . . . . . . . . . . . . . . . . . . . . . . .

. . . . . . . . . . . . . . . . . . . .

. .

.

 

113

Chapter 14: Gastrointestinal Disease . . . . . . . . . . . . .

. . . . . . . . . . . . . . . . . . . .

. .

.

139

Chapter 15: Renal and Urologic Disorders . . . . . .

. . . . . . . . . . . . . .

. .

. 155. . . . . . . .

Chapter 16: Endocrine Disorders .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. ..

.. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. ..

.. ..

..

 

167

Chapter 17: Orthopedic Disorders . . . . . . . . . . . . . .

. . . . . . . . . . . . . . . . . .

. .

.

 

179. . .

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v

USMLE Step 2 CK λ Pediatrics

Chapter 18: Rheumatic and Vasculitic­ Disorders . . . . . . . . . . . . . . . . . . . . . . . . . . . 187

Chapter 19: Hematology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 197

Chapter 20: Oncology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 213

Chapter 21: Neurology . . . . . . . . . . .

. . . . . . . . . . . . .

.

. . . . . . . . . . . .

 

. 219. . . . . . . . .

Chapter 22: Infectious Disease . . . . . . . .

. . . . . . . . . . . . . . . .

.

. . . . . . . . . . . . . . .

.

237

Chapter 23: Adolescence . . . . . . . .

. . . . . . . . . . .

.

. . . . . . . . . .

.

261. . . . . . . . . . . .

Index . . . . . . . . . . . . . . . . . . . . . .

. . . . . . . . . .

.

. . . . . . . . .

.

267. . . . . . . . . . .

Additional resources available at kaptest.com/usmlebookresources

vi

The Newborn

1

Chapter Title

Learning Objectives

Calculate an Apgar score

Use knowledge of birth injuries to predict symptomology

Demonstrate understanding of newborn screening, fetal growth/maturity, and neonatal infections

APGAR SCORE

A newborn infant at birth is noted to have acrocyanosis, heart rate 140/min, and grimaces to stimulation. She is active and has a lusty cry. What is her Apgar score?

Table 1-1. Apgar Scoring System

 

Evaluation

 

 

0 Points

 

 

1 Point

 

 

2 Points

 

 

 

 

 

 

 

 

 

 

 

 

 

Heart rate

0

 

<100/min

 

>100/min

 

 

 

 

 

 

 

 

 

 

 

 

Respiration

None

Irregular, shallow, gasps

 

Crying

 

 

 

 

 

 

 

 

 

 

 

 

Color

Blue

Pale, blue extremities

 

Pink

 

 

 

 

 

 

 

 

 

 

 

 

Tone

None

Weak, passive

 

Active

 

 

 

 

 

 

 

 

 

 

 

 

Reflex irritability

None

Facial grimace

 

Active withdrawal

 

 

 

 

 

 

 

 

 

 

 

 

Apgar scores are routinely assessed at 1 and 5 minutes, and every 5 minutes thereafter as long as resuscitation is continuing.

The 1-minute score gives an idea of what was going on during labor and delivery.

The 5-minute score gives an idea of response to therapy (resuscitation).

In general, the Apgar score is not predictive of outcome; however, infants with score 0−3 at ≥5 minutes compared to infants with score 7−10 have a worse neurologic outcome.

Published by dr-notes.com

1

 

 

 

USMLE Step 2 CK λ Pediatrics

Newborn Care

Vitamin K IM

Prophylactic eye erythromycin

Umbilical cord care

Hearing test

Newborn screening tests

BIRTH INJURIES

On physical exam, a 12-hour-old newborn is noted to have nontender swelling of the head that does not cross the suture line. What is the most likely diagnosis?

Table 1-2. Common Injuries During Deliveries

 

Injury

 

 

Specifics

 

 

Outcome

 

 

 

 

 

 

 

 

 

 

Skull fractures

In utero from pressure against bones or

•  Linear: no symptoms and no treatment needed

 

 

 

forceps; linear: most common

•  Depressed: elevate to prevent cortical injury

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Brachial palsy

 

Erb-Duchenne: C5–C6; cannot abduct

 

Most with full recovery (months); depends on

 

 

 

 

shoulder; externally rotate and supinate

 

whether nerve was injured or lacerated; Rx: proper

 

 

 

 

forearm; Klumpke: C7–C8 ± T1; paralyzed

 

positioning and partial immobilization; massage

 

 

 

 

hand ± Horner syndrome

 

and range of motion exercises; if no recovery in

 

 

 

 

 

 

 

3–6 mo, then neuroplasty

 

 

 

 

 

 

 

 

 

 

Clavicular fracture

 

Especially with shoulder dystocia in vertex

 

Palpable callus within a week; Rx: with

 

 

 

 

position and arm extension in breech

 

immobilization of arm and shoulder

 

 

 

 

 

 

 

 

 

 

Facial nerve palsy

 

Entire side of face with forehead; forceps

 

Improvement over weeks (as long as fibers were

 

 

 

 

delivery or in utero pressure over facial nerve

 

not torn); need eye care; neuroplasty if no

 

 

 

 

 

 

 

improvement (torn fibers)

 

 

 

 

 

 

 

 

 

 

Caput succedaneum

 

Diffuse edematous swelling of soft tissues of

 

Disappears in first few days; may lead to molding

 

 

 

 

scalp; crosses suture lines

 

for weeks

 

 

 

 

 

 

 

 

 

 

Cephalohematoma

 

Subperiosteal hemorrhage: does not cross

 

May have underlying linear fracture; resolve in 2 wk

 

 

 

 

suture lines

 

to 3 mo; may calcify; jaundice

 

 

 

 

 

 

 

 

 

2

Chapter 1 λ The Newborn

PHYSICAL EXAMINATION

A newborn infant has a blue-gray pigmented lesion on the sacral area. It is clearly demarcated and does not fade into the surrounding skin. What is the most likely diagnosis?

A newborn has a flat, salmon-colored lesion on the glabella, which becomes darker red when he cries. What is the best course of management?

Table 1-3. Physical Examination—Common Findings

 

Finding/Diagnosis

 

 

Description/Comments

 

 

 

 

 

 

 

 

Skin

 

 

 

 

Cutis marmorata

 

Lacy, reticulated vascular pattern over most of body when baby is cooled; improves over first

 

 

 

 

month; abnormal if persists

 

Salmon patch

 

Pale, pink vascular macules; found in nuchal area, glabella, eyelids; usually disappears

 

(nevus simplex)

 

 

 

 

Mongolian spots

 

Blue to slate-gray macules; seen on presacral, back, posterior thighs; > in nonwhite infants;

 

 

 

 

arrested melanocytes; usually fade over first few years; differential: child abuse

 

Erythema toxicum,

 

Firm, yellow-white papules/pustules with erythematous base; peaks on second day of life; contain

 

neonatorum

 

eosinophils; benign

 

Hemangioma

 

Superficial: bright red, protuberant, sharply demarcated; most often appear in first 2 months;

 

 

 

 

most on face, scalp, back, anterior chest; rapid expansion, then stationary, then involution (most

 

 

 

 

by 5–9 years of age); Rx: beta blockers, embolization; deeper: bluish hue, firm, cystic, less likely

 

 

 

 

to regress; Rx: (steroids, pulsed laser) only if large and interfering with function

 

 

 

 

 

 

 

Head

 

 

 

 

Preauricular

 

Look for hearing loss and genitourinary anomalies.

 

tags/pits

 

 

 

 

Coloboma of iris

 

Cleft of lid, iris, lens, retina, or choroid. In iris, manifests as keyhole appearance at the 6 o’clock

 

 

 

 

position. May be autosomal-dominant or part of CHARGE syndrome.

 

Leukocoria—white

 

Retinoblastoma; cataract; retinopathy of prematurity; retinal detachment; larval granulomatosis

 

reflex

 

 

 

 

Aniridia

 

Hypoplasia of iris; defect may go through to retina; association with Wilms tumor

 

 

 

 

 

 

 

Extremities

 

 

 

 

Polydactyly

 

Extra digit, partial digit, or cleft digit after the 4th finger (ulnar side); world’s most common minor

 

 

 

 

malformation; usually surgically removed at 1–2 years of age

 

 

 

 

 

 

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