The optimal management strategy for AKI is the identica­tion of at-risk patients and preventively managing their care to minimize the risk of developing AKI.The goal is to main­tain euvolemia and normotension and avoid nephrotoxic drugs throughout their clinical course. Resuscitation with balanced crystalloid solutions, which are more similar to human plasma with respect to electrolytes, pH, and buffer capacity, is preferred. Once AKI has developed, there is no specic treatment to regain kidney function. The goal is to maintain adequate renal perfusion and to avoid further kid­ney injury, allowing the return of renal function. Supportive care, optimizing volume status, and time will dictate the clinical course. Conversion of oliguric to non-oliguric renal failure with use of diuretics will not alter the course but may help manage volume status and avoid the need for renal replacement therapy (RRT).