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Gallstone Ileus

KeshavKooragayala andYoungK.Hong
50
Way Question May BeAsked?
A 45-year-old female with a history of gallstones presents to the hospital with abdominal pain, nausea, and vomiting for 1week. She has no prior surgical history. She undergoes an abdominal X-ray in the emergency room, which identies a radiolucent stone in the small bowel and pneumonia.
How toAnswer?
Full History
• Onset of symptoms
• Any history of biliary symptoms (RUQ pain, postprandial abdominal pain)
• Nausea
• Emesis (bilious, non-bilious)
• PO tolerance
• Fevers
• Jaundice
• “Tumbling obstruction”—intermittent symptoms of obstruction as the stone intermittently blocks the lumen of the intestine

Surgical Procedure

Preoperative resuscitation, enteric decompression with NGT
• Management is focused on relieving bowel obstruction, and not the biliary stula
• Exploratory laparotomy
• Longitudinal enterostomy proximal to stone, with trans­verse closure of enterotomy
• Delayed management of biliary disease
• Cholecystectomy with/without takedown of biliary stula should be considered based on the patient’s specic comorbidities

Common Curveballs

• It is essential to examine the remainder of the bowel for additional stones that can cause recurrent symptoms
• The patient has postoperative bowel obstruction (missed second stone)
• Patient is unstable
Full Physical Examination
• Abdominal exam
• Evaluation of character of emesis
• Check for hernias as a source of bowel obstruction
Diagnostic Tests
• CT scan with IV and/or PO contrast
• RUQ ultrasound
K. Kooragayala · Y. K. Hong (*) Department of Surgery, Cooper University Healthcare, Camden, NJ, USA e-mail: kooragayala-keshav@CooperHealth.edu;
Hong-young@cooperhealth.edu
© The Author(s), under exclusive license to Springer Nature Switzerland AG 2025 M. Neff et al. (eds.), Passing the General Surgery Oral Board Exam, https://doi.org/10.1007/978-3-031-78244-2_50

Clean Kills

• Performing an up-front cholecystectomy and takedown of biliary stula before addressing gallstone.
• Performing a one-stage surgery in the setting of intense inammation in the right upper quadrant would place the patient at risk for signicant morbidity.
• Not milking the stone back from the terminal ileum (where it typically gets lodged).
165
166
Words ofWisdom
When managing a patient with gallstone ileus, it is crucial to evaluate the entirety of the bowel so as not to miss secondary stones. While it may be tempting to take down the choleduodenal stula, the primary objective of the index operation is to relieve the intestinal obstruction.
K. Kooragayala and Y. K. Hong

Choledochal Cyst

KeshavKooragayala andYoungK.Hong
51

Concept

In choledochal cysts, the pancreatic duct often joins the com­mon bile duct outside the pancreas, creating a long common channel allowing for biliary reux, leading to inammatory changes and cyst formation.
Characterization of Cyst Type
• Type I: Fusiform cysts: 50% of cysts, highest risk of malignancy
• Type II: Saccular diverticula of common bile duct
• Type III: Intraduodenal cysts
• Type IV: Multiple cysts, which could be intra- or extra-hepatic
– Type IVa: Intrahepatic disease – Type IVb: Isolated extrahepatic disease
• Type V: Caroli disease: multiple intrahepatic cysts
Way Question May BeAsked?
A 53-year-old female with a history of pancreatitis presents with abdominal pain, jaundice, and palpable mass. Alternatively, this patient may present with cholangitis.
How toAnswer?
Full History
• Onset of symptoms
• Any history of biliary symptoms (right upper quadrant (RUQ) pain, postprandial abdominal pain)
• Nausea
• Emesis (bilious, nonbilious)
• PO tolerance
• Fevers
• Jaundice
• History of any anomalies seen at birth, genetic syndromes, etc.
Full Physical Examination
• Abdominal exam
• Lymph node exam
• Functional assessment
Diagnostic Tests
• Laboratory studies, including liver function tests (LFTs), complete blood count (CBC), and lipase
• CT scan with IV and/or PO contrast
• RUQ ultrasound
• MRCP

Surgical Management

• Surgical management is based on the location and type of the cyst
• For type I/II, surgical excision of the cyst, cholecystec­tomy with or without Roux-en-Y hepaticojejunostomy is performed
• For type III cysts, the intra-duodenal segment may neces­sitate a pancreaticoduodenectomy for complete removal of the cyst or resection through a transduodenal approach
• For type IV, excision of all cysts, including segmental liver resection and reconstruction based on individual patient history
• For type V, liver transplantation is often the only treat­ment option for the eradication of all cystic tissue
K. Kooragayala · Y. K. Hong (*) Department of Surgery, Cooper University Healthcare, Camden, NJ, USA e-mail: kooragayala-keshav@CooperHealth.edu;
Hong-young@cooperhealth.edu
© The Author(s), under exclusive license to Springer Nature Switzerland AG 2025 M. Neff et al. (eds.), Passing the General Surgery Oral Board Exam, https://doi.org/10.1007/978-3-031-78244-2_51
167
168
K. Kooragayala and Y. K. Hong

Common Curveballs

• For patients presenting with cholangitis, clearance of infection should be managed before surgical resection
• The goal of resection is to reduce the risk of malignant potential
• Postoperative complication: stricture

Clean Kills

• After the excision of the choledochal cyst, performing a biliary–enteric bypass is critical if there is concern about biliary stricture.
• Incomplete cyst excision can lead to malignant conver­sion of remnant cystic tissue.
Words ofWisdom
When managing a patient with choledochal cysts, it is impor­tant to advise patients that the purpose of surgery is due to the malignant potential of the cystic tissue. Excision and reconstruction of the biliary tree can require complex recon­structive procedures and is best done at quaternary care cen­ters by biliary/pancreatic surgeons.

Choledocholithiasis

KeshavKooragayala andYoungK.Hong
52
Way Question May BeAsked?
A 53-year-old female with a history of weight loss presents with abdominal pain, jaundice, and intermittent pain. She has elevated serum bilirubin, alkaline phosphatase, and a dilated CBD on ultrasound. She has been afebrile but noted that these symptoms have progressed over the last week.
How toAnswer?
Full History
• Onset of symptoms
• Any history of biliary symptoms (RUQ pain, postprandial abdominal pain)
• Nausea
• Emesis (bilious, nonbilious)
• PO tolerance
• Fevers
• Jaundice
Charcot Triad: fevers, jaundice, RUQ pain Reynold’s Pentad: triad+hypotension and altered mental
status
Full Physical Examination
• Vital signs
• Abdominal exam
Diagnostic Tests
• Laboratory studies, including LFTs, CBC, and lipase
– Serum bilirubin, alkaline phosphatase, liver enzymes
• RUQ ultrasound—best initial test
• MRCP
• ERCP: diagnostic and therapeutic

Surgical Management

• NPO, IVF, and IV antibiotics before surgery
• ERCP with sphincterotomy to decompress the CBD fol­lowed by laparoscopic cholecystectomy
• If ERCP is unavailable, perform laparoscopic cholecys­tectomy with intraoperative cholangiogram through a transcystic approach
• If stones are too large or unable to cannulate, can perform CBD exploration
– Stay sutures on the duct, longitudinal choledochotomy
with clearance of duct
– Duct should be closed over T-tube

Common Curveballs

• If lling defects are identied during IOC during routine laparoscopic cholecystectomy, they can proceed with ERCP after surgery.
• Percutaneous transhepatic cholecystostomy tube or laparoscopy- assisted ERCP access is helpful in patients with RNY bypass anatomy.
• If stones are impacted at the ampulla, perform transduo­denal sphincterotomy.
• If stones are unable to be removed, perform choledocho­duodenostomy or RNY hepaticojejunostomy.
• The CBD will be small.
• The patient will have had a previous gastric bypass or pre­vious duodenal switch.
K. Kooragayala · Y. K. Hong (*) Department of Surgery, Cooper University Healthcare, Camden, NJ, USA e-mail: kooragayala-keshav@CooperHealth.edu;
Hong-young@cooperhealth.edu
© The Author(s), under exclusive license to Springer Nature Switzerland AG 2025 M. Neff et al. (eds.), Passing the General Surgery Oral Board Exam, https://doi.org/10.1007/978-3-031-78244-2_52
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170
K. Kooragayala and Y. K. Hong

Clean Kills

• It is critical to evaluate for signs of cholangitis, which could progress to systemic sepsis without prompt treat­ment
• Not leaving a T-tube if performing CBD exploration
Words ofWisdom
Choledocholithiasis with secondary stones from the gall­bladder is a typical disease process. While some are inciden­tally identied, biliary decompression and cholecystectomy are considered the standard of care to prevent recurrent symptoms and complications. Do not perform CBD explora­tions on small CBDs. They will stricture or leak or both, and your patient will not do very well.

Bile Leak

ClaraZhu andYoungK.Hong
53

Concept

A bile leak may occur after cholecystectomy, with similar preoperative symptoms. Reported incidence is approxi­mately 0.5–1%. Early detection of bile leaks allows for prompt treatment and avoidance of postoperative morbidity. Very important to rule out a major bile duct injury promptly.
Way Question May BeAsked?
A 45-year-old female with a history of obesity undergoes laparoscopic cholecystectomy for symptomatic cholelithia­sis. She presents to your ofce 5 days after the operation with right upper quadrant abdominal pain and fevers.
How toAnswer?
Full History
• Onset of symptoms
• Abdominal pain
• Nausea
• Emesis
• PO tolerance
• Fevers
• Jaundice
• Operative details of cholecystectomy
• Indication for cholecystectomy
• If a drain was left in the index operation. If so, what is the quality of and the amount of uid?
Full Physical Examination
• Vital signs
C. Zhu · Y. K. Hong (*) Department of Surgery, Cooper University Healthcare, Camden, NJ, USA e-mail: Zhu-clara@cooperhealth.edu;
Hong-young@cooperhealth.edu
– Abdominal tenderness on palpation – Peritonitis – Jaundiced skin – Scleral icterus
Diagnostic Tests
• Labs including CBC, BMP, LFTs, INR – Right upper quadrant ultrasound—least sensitive test
but inexpensive but a fast and safe initial test
– CT abdomen—more sensitive than ultrasound but can-
not differentiate biloma from abscess, hematoma, or simple uid
– HIDA—the most specic test for biliary leak and can
aid inlocalizing the source of the leak

Surgical Procedure

• IR drainage—the initial procedure to drain the biloma and
send uid for culture. Drain volume also aids in further decision-making.
• ERCP—if the output from a percutaneous drain is high or
increasing, ERCP has a high success rate of improving the leak volume. Sphincterotomy and CBD stent place­ment divert the ow of bile through the ampulla. However, patients will require stent removal or exchange at 6weeks.
• It is infrequent to require a washout operation. However,
this would be indicated when a large-volume leak causes diffuse peritonitis.

Common Curveballs

• Interventional radiology is not available – The patient has no window for interventional radiol-
ogy drainage
– The patient has Roux-en-Y anatomy, which precludes
normal ERCP
© The Author(s), under exclusive license to Springer Nature Switzerland AG 2025 M. Neff et al. (eds.), Passing the General Surgery Oral Board Exam, https://doi.org/10.1007/978-3-031-78244-2_53
171
172
C. Zhu and Y. K. Hong

Clean Kills

• Failure to check liver function tests
• Failure to resuscitate and start antibiotics in patients with sepsis
• Failing to obtain imaging to establish diagnosis
• Failing to drain the biloma
• Failing to perform ERCP after high drainage volume
• Performing surgery before noninvasive interventions
Words ofWisdom
When evaluating a patient with a postoperative bile leak, the rst step is to establish a diagnosis, as a differential diagnosis may include postoperative hematoma or abscess. The major­ity of bile leaks can be managed nonoperatively with percu­taneous drainage by interventional radiology and ERCP with sphincterotomy and stent placement.

Bile Duct Injury

ClaraZhu andYoungK.Hong
54

Concept

Early workup and transfer to a center with hepatobiliary experience are components of safe management. If a bile leak is detected intraoperatively and hepatobiliary capabili­ties are unavailable, it is best to widely drain the area and transfer the patient to a higher level of care.
Way Question May BeAsked?
There is a 60-year-old male on whom you perform a laparo­scopic cholecystectomy. The gallbladder is densely inamed. After transection of what you believe to be the cystic duct, you notice bile leaking from an unclear source. You decide to perform an intraoperative cholangiogram and do not see any contrast ow into the duodenum.
How toAnswer?
Full History
• Indications for cholecystectomy
• When the cholecystectomy was performed relative to the discovery of the injury
• Operative report of the cholecystectomy
• Previous surgical anatomy
• Abdominal pain
• Nausea or emesis
• Fevers or chills (indications of sepsis)
Full Physical Examination
• Vital signs
– Scleral icterus
C. Zhu · Y. K. Hong (*) Department of Surgery, Cooper University Healthcare, Camden, NJ, USA e-mail: Zhu-clara@cooperhealth.edu; Hong-young@cooperhealth.edu
– Jaundice of the skin – Abdominal pain – Peritonitis – Presence of a drain from cholecystectomy
Diagnostic Tests
• Labs including CBC, BMP, LFTs, INR.
• Cholangiography should be performed if a ductal injury is suspected intraoperatively and equipment is available.
• Right upper quadrant ultrasound—again, this test is non­specic but a safe and inexpensive test to order for com­plications after cholecystectomy.
• CT scan is also a high-yield test and allows for visualiza­tion of uid collections and associated hepatic vascular injury.
• MRCP is critical to delineate the level of injury.

Surgical Procedure

• If a bile leak is detected intraoperatively and hepatobiliary capabilities are unavailable, it is prudent to widely drain the area and transfer the patient to a higher level of care.
• If the patient has a delayed presentation (greater than 4 days), the leak should be temporized with a plan for operative repair in approximately 8 weeks. Short-term intervention includes percutaneous drainage of a biloma and an external biliary drain for complete ductal transection.
• Partial duct injuries <50% circumference can be repaired with absorbable suture over a T-tube. If the two ends can be brought together without tension, the duct can be pri­marily anastomosed over a T-tube. However, the bile duct will often retract, causing tension.
• Often, the safest surgical option is a Roux-en-Y hepatico­jejunostomy (HJ):
– Division of the jejunum 30 cm from the ligament of
Treitz.
© The Author(s), under exclusive license to Springer Nature Switzerland AG 2025 M. Neff et al. (eds.), Passing the General Surgery Oral Board Exam, https://doi.org/10.1007/978-3-031-78244-2_54
173
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C. Zhu and Y. K. Hong
– Bring up the limb to the debrided proximal edge of the
bile duct.
– Creation of the hepaticojejunostomy anastomosis with
absorbable suture.
– Creation of small bowel anastomosis 50 cm from the
HJ to prevent bile reux.

Common Curveballs

• The timing is 2 weeks or greater from the index operation
• The level of the injury is above the conuence

Clean Kills

• Performing a choledochoduodenostomy when there is tension
• Attempting to perform an HJ without experience
• Doing a primary repair for an injury that is greater than 50% circumference
• The examiner asks you how you explain the injury to the patient/family and you are not honest and upfront in your explanation
Words ofWisdom
The most important factors after diagnosis of a bile duct injury are timing from the index operation, level of the injury, and extent of the injury. The safest initial option is to transfer to a center with hepatobiliary experience. Early diagnosis is amenable to either primary repair or hepaticojejunostomy. Late diagnoses should have drainage and interval hepaticojejunostomy.