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120 Deep Vein Thrombosis
415
For patients with BMI >40, dose should be 7500units q8hr
– Enoxaparin dosing: 40mg qday
For patients with BMI>40, dose should be 40mg q12hr
• This patient should also have compression stockings or pneumatic compression if he is unable to ambulate while he is hospitalized.
• This patient is undergoing an epidural catheter placement, which is a high-risk procedure for bleeding into the spinal canal and paralysis; therefore it is appropriate to hold his DVT prophylaxis.
• For epidural placement, the amount of time you need to hold DVT prophylaxis will depend on if you gave heparin or enoxaparin.
– Heparin: Hold dose for 6 h prior to epidural
placement.
– Enoxaparin: If 30 or 40mg daily dose, hold DVT pro-
phylaxis for 12h.
If 1 mg/kg q12 dose, hold DVT prophylaxis for 24h prior to the procedure.
• The timing for restarting DVT prophylaxis is as follows:
– Heparin: can continue after epidural is placed. Hold
for 4 h prior to removal of the epidural. Can restart 2–4h after the epidural is removed.

Bonus Points

Thrombolysis and Surgical Treatment of DVT
• There is limited role for chemical thrombolysis with tis­sue plasminogen activator in a postoperative patient because the risk of life-threatening hemorrhage is too high (Gutt etal. 2005).
• Surgical thrombectomy should be reserved for patients with massive thrombosis and limb-threatening isch-
emia (phlegmasia cerulea dolens) to avoid venous gan­grene (Gutt etal. 2005).
Words ofWisdom
Ensuring appropriate chemical prophylaxis is indicated in nearly all surgical and trauma patients. Early prophylaxis can help to prevent morbidity and even mortality in patients who are at moderate to high risk. Having a heightened aware­ness of these populations may lead to early detection even in patients who are on prophylactic dosing to ensure that they are then receiving therapeutic dosing as needed. Similarly, it is important to know when alternative measures are neces­sary for patients with contraindications to chemoprophylaxis (intracranial hemorrhage, etc.).

Bibliography

Anderson D, Morgano G, etal. American Society of Hematology 2019
guidelines for management of venous thromboembolism: preven­tion of venous thromboembolism in surgical hospitalized patients. Blood Adv. 2019;3(23):3898–944.
Gutt MD, Oniu MD, et al. Prophylaxis and treatment of deep vein
thrombosis in general surgery. Am J Surg. 2005;189(1):14–22.
Kearon C, Akl EA. Duration of anticoagulant therapy for
deep vein thrombosis and pulmonary embolism. Blood. 2014;124(12):1794–801. https://doi.org/10.1182/
blood- 2013- 12- 512681.
O’Donnell M, Weitz J.Thromboprophylaxis in surgical patients. Can J
Surg. 2003;46(2):129–35.
Perrotti MD, Sadri MD, etal. One size does not t all: venous throm-
boembolism prophylaxis in colorectal cancer. J Soc Laparosc Robot Surg. 2020;24(3):e2020.00038. https://doi.org/10.4293/
JSLS.2020.00038.
Rumbaugh K, Schmidt L. Venous thromboembolism prophylaxis
guidelines. Vanderbilt University Medical Center; 2018.
Part XVI
Pediatric
Gastroesophageal Reflux Disease inPediatric Patients
ErikaB.Lindholm
121

GERD

Scenario
A 2-month-old baby, born prematurely at 29 weeks’ gesta­tion, presents with inability to take adequate PO and has an NGT placed. You are consulted for a gastrostomy tube and possible fundoplication. She is currently getting goal feeds, but they are unable to give bolus feeds because she starts spitting up. Nurses note that she arches during feeds periodi­cally and has small spit-ups during continuous feeds. She is otherwise healthy.
• Medications should be reviewed to determine if this infant has even been on antacid therapy. If she has been treated, it is important to know if her symptoms have improved.
• Patient has no signs of pulmonary disease, or ATLE.
• After a trial of antacid therapy, the patient fails to improve.
• What additional test would you like to perform?
– Upper gastrointestinal imaging to check for anatomy is
normal.
– Impedance probe is ordered. The patient comes off the
PPI for 1week and then test shows reux at time of symptoms. After a long discussion about the risks and benets, the parent opts for fundoplication at the time of gastrostomy tube.
• Describe laparoscopic Nissen fundoplication.
– Preoperative antibiotics and large OG tube or bougie
are placed by anesthesia.
– Obtain access at umbilicus using a 5 mm port; insuf-
ate to 8mmHg.
– Make a small subxiphoid incision for placement of the
liver retractor. Two additional ports are placed in the right and left abdomen.
E. B. Lindholm (*) Division of Pediatric Surgery, Children’s Regional Hospital, Cooper University, Camden, NJ, USA e-mail: Lindholm-Erika@cooperhealth.edu
– Minimal dissection has been shown to prevent compli-
cations with wrap migration. The gastric splenic liga­ment and short gastrics are ligated with LigaSure. Once the greater curvature is freed, a small window is made in the gastrohepatic ligament.
– A retrocrural space is dissected bluntly and the fundus
of the stomach pulled through this small window. A few sutures are then placed to approximate the 360° wrap.
– Following this gastrostomy tube is placed in the stan-
dard fashion.
• Postoperative management – Multiple multicenter trials have shown rapid scheduled
feeds should be given via the gastrostomy tube with patients on full feeds within 24h.
– In patients without feeding tube access, diet is similar
to an adult with liquids for a few days and then solids. No carbonated beverages, no bread, and no large pieces of meat.

Clean Kills

• Performing a wrap in patients with oropharyngeal dys-
motility which will make it more difcult for them to push food down the fundoplication.
• Failure to perform the correct workup on these patients
and failing to have a proper risk discussion with the family.

Bonus Points

• Literature does not support the use of fundoplication as a
preventive measure in neurologically devastated children. Unless there are concerning symptoms that are related to reux, most patients can safely grow out of their symptoms.
© The Author(s), under exclusive license to Springer Nature Switzerland AG 2025 M. Neff et al. (eds.), Passing the General Surgery Oral Board Exam, https://doi.org/10.1007/978-3-031-78244-2_121
419
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E. B. Lindholm
Words ofWisdom
• This is a disease that has wide practice variation patterns in regard to surgical treatment. Some pediatric centers perform many anti-reux procedures, and some perform hardly any. The key is that every patient should be evalu­ated systematically and care taken to ensure that surgery risks outweigh the benets.

Bibliography

www.surgicalcore.org. SCORE. Gastroesophageal Reux/Barrett’s
Esophagus (Pediatric/Fellowship Level) August 17, 2023.
Townsend JCM, Beauchamp RD, Evers BM, & Mattox KL. (2016).
Sabiston textbook of surgery (20th ed.). Elsevier - Health Sciences Division.
Holcom and Ashcraft’s Pediatric Surgery (7th ed.). Chapter 73.
Gastroesphageal Reux Disease. Hollwarth M. 2012.

Hypertrophic Pyloric Stenosis

M.VirginiaButchy, JohnWilliamson, andErikaB.Lindholm
122

Pyloric Stenosis

Scenario
A 3-week-old infant presents to the Emergency Department with non-bloody, non-bilious vomiting, which happens fre­quently with every feed. The dad describes vomiting as ini­tially “spit-ups” with every feed but it has progressed to forceful, projectile vomiting.
• What is the appropriate preoperative patient assessment?
– Preoperative resuscitation and correction of electrolyte
abnormalities is essential. Failure to establish adequate resuscitation can lead to postoperative apnea to increase respiratory carbon dioxide and compensate for the metabolic alkalosis.
– Anesthesia can allow for placement of a nasogastric or
orogastric tube for gastric decompression and leak test postoperatively.
• What is your preferred imaging modality?
– Ultrasound is the gold standard for diagnosis: pyloric
muscle thickness of 4mm (3.5in premature infants) and a length of 16mm or greater.
– Upper gastrointestinal imaging can also be utilized and
can see an elongated pyloric channel; barium should be seen exiting the stomach to exclude pyloric web or atresia.
• Describe open vs laparoscopic pyloromyotomy.
– Fredet-Ramstedt pyloromyotomy (open)
M. V. Butchy · J. Williamson Department of Surgery, Cooper University Hospital, Camden, NJ, USA e-mail: butchy-margaret@cooperhealth.edu;
williamson.john@lha6.navy.mil
E. B. Lindholm ( Department of Surgery, Cooper University Hospital, Camden, NJ, USA
Division of Pediatric Surgery, Children’s Regional Hospital, Cooper University, Camden, NJ, USA e-mail: Lindholm-Erika@cooperhealth.edu
*)
Obtain abdominal access, either periumbilical or right upper quadrant. Retract liver superiorly and deliver pylorus through wound. Open serosa sharply; from proximal to the hyper­trophied muscle to proximal to the pyloric vein, bluntly divide muscle bers to expose the submucosa. Check for leak.
– Laparoscopic pyloromyotomy:
Obtain access at the umbilicus using a 5mm port; insufate to 8mmHg. Make small abdominal incisions so that the atrau­matic grasper and extended cautery blade can enter the abdomen without port placement. From proximal to the hypertrophied muscle to proximal to the pyloric vein, bluntly divide muscle bers to expose the submucosa. Conrm that divided pyloric muscle halves move independently, conrming adequate myotomy. Perform leak tests using air insufated via OG or NGT.
– Goal of both procedures is to cut the hypertrophied cir-
cular pyloric muscle without causing mucosal injury.
– Laparoscopic pyloromyotomy is associated with
shorter length of stay and lower surgical site infection.
– Full thickness mucosal perforation is more common
with laparoscopic approach but incidence is rare (<1%).
• After completing the pyloromyotomy, you have a positive
leak test; what is the next step?
– Perforation occurs in approximately 1% of patients. If
this is identied intraoperatively, the defect should be closed with absorbable suture and can be bolstered with omentum.
– A new myotomy should be made 90–180° from the
original incision.
– Hold feeding for 24h.
© The Author(s), under exclusive license to Springer Nature Switzerland AG 2025 M. Neff et al. (eds.), Passing the General Surgery Oral Board Exam, https://doi.org/10.1007/978-3-031-78244-2_122
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M. V. Butchy et al.
– If there is additional concern, a water-soluble study
can be performed.
• Operative complications: incomplete myotomy, duodenal
or pyloric leak, hernia, wound infection, or dehiscence
– Infants with persistent emesis 7–10 days postopera-
tively should be imaged with a contrast study to evalu­ate for incomplete myotomy.
– Differential for persistent vomiting: GERD, discoordi-
nation of gastric peristalsis, gastric atony, incomplete myotomy, and leaks.
Alternate Scenario
A 3-week-old infant presents to the Emergency Department with non-bloody, non-bilious vomiting and lethargy, which happen frequently with every feed. The dad describes vomit­ing as initially “spit-ups” with every feed but it has pro­gressed to forceful, projectile vomiting. Physical exam shows dry mucous membranes, sunken fontanelle, and limp, lethar­gic infant.
• What laboratory tests would you order to assess the patient’s resuscitation status?
– A basic metabolic panel should be ordered. The serum
carbon dioxide (<30mmol/L), chloride (>100mmol/L), and potassium (4.5–6.5 mmol/L) can help guide resuscitation.
• What are the electrolyte abnormalities seen in patients
with HPS?
– Characteristic electrolyte abnormalities: hypokalemic,
hypochloremic metabolic alkalosis (elevated bicarbon­ate). Loss of hydrochloric acid secondary to persistent emesis leads to dehydration and hypokalemic, hypo­chloremic metabolic alkalosis.
• How would you resuscitate a neonate with hypokalemic,
hypochloremic metabolic alkalosis?
– Goals of resuscitation: Establish adequate UOP 2.0cc/
kg/hr. and serum bicarbonate of <30mEq/L prior to
surgery. – Start with a bolus of 20ml/kg bolus of normal saline. – Additional resuscitation with 5% dextrose, 0.45%
sodium chloride, and 20mEq/L potassium is appropri-
ate, at 1.25–2 times maintenance intravenous uid
resuscitation rate. – Electrolytes should be checked every 6 h and a new
bolus can be given until labs normalize and the alkalo-
sis resolves. – Preoperatively resuscitation and correction of electro-
lyte abnormalities is essential. Failure to establish ade-
quate resuscitation can lead to postoperative apnea to
increase respiratory carbon dioxide and compensate
for the metabolic alkalosis.
• Further recommendations
– Infants can start ad lib feeding immediately post-
procedure. Vomiting is common post-procedure; pro­viders are encouraged to “feed through it” and resume q3 feeds.
– Studies show that ad lib feeding can get the patient to
full feeds faster.
• Long-term follow-up

Clean Kills

• Taking a newborn to the OR prior to adequate resuscita­tion, continue to bolus until normal electrolytes. May take a few days for severely dehydrated patients.
• Failure to recognize a delayed perforation in the postop­erative setting. A concerning exam, or pain requiring more than Tylenol, should raise alarm, and the denitive test would be a UGI to check for leak.

Bonus Points

• Hypokalemic, hypochloremic metabolic alkalosis is on every test.
• The worse the electrolyte abnormalities, the longer it will take the baby to resume full feeds as the stomach needs to relearn how to pass food through the pylorus.
Words ofWisdom
• The key to a safe surgery is ensuring that the baby has normal electrolytes. In this modern age, most patients have access to ultrasound for diagnosis and thus present earlier than previously. Most patients are able to go to the OR within 24h, and then most are tolerating full feeds at 24h. In the operating room, if the pylorus does not look enlarged and is not typical of pyloric stenosis, do not pro­ceed with pyloromyotomy as likely this will cause perfo­ration. Caution when extending the incision onto both the stomach and duodenum is important to prevent perfora­tion which can be deadly if diagnosis is delayed.

Bibliography

www.surgicalcore.org. SCORE. Inguinal Hernia (Pediatric/Fellowship
Level) August 19, 2023.
Townsend, J. C. M., Beauchamp, R. D., Evers, B. M., & Mattox, K. L.
(2016). Sabiston textbook of surgery (20th ed.). Elsevier - Health Sciences Division.
Holcom and Ashcraft’s Pediatric Surgery (7th ed.). Chapter 50. Inguinal
Hernia. Hollwarth M. 2019.

Pediatric Inguinal Hernia

M.VirginiaButchy, JohnWilliamson, andErikaB.Lindholm
123

Inguinal Hernia

Scenario
“A 3-month-old male presents with intermittent groin bulge. The mom reports that she noticed a bulge in the patient’s scrotum when she was changing his diaper and he was cry­ing. Groin bulge disappears when the baby calms down. No bulge is present on examination today.”
• How would you assess and diagnose your patient? – Diagnosis of a hernia is done clinically based on
detailed history and physical exam. Parents, guardians, and primary care physicians are extremely helpful in diagnosis.
– Bulging can be intermittent; it’s common to have a
normal exam and a suggestive history.
– Physical exam: Palpate, identify, and document testic-
ular exam in males; palpate the external the ring lateral to the pubic tubercle; attempt provocative maneuvers (raising head, blowing through a straw, coughing, extending hips).
– Transillumination is not helpful in differentiating
hydrocele vs inguinal hernia for pediatric patients because the bowel wall is so thin.
– Ultrasound can be used but is operator dependent and
unnecessary in the diagnosis of an inguinal hernia.
• Describe open vs laparoscopic inguinal hernia repair. – Open inguinal hernia repair
M. V. Butchy · J. Williamson Department of Surgery, Cooper University Hospital, Camden, NJ, USA e-mail: butchy-margaret@cooperhealth.edu;
williamson.john@lha6.navy.mil
E. B. Lindholm ( Department of Surgery, Cooper University Hospital, Camden, NJ, USA
Division of Pediatric Surgery, Children’s Regional Hospital, Cooper University, Camden, NJ, USA e-mail: Lindholm-Erika@cooperhealth.edu
*)
Identify the anterior superior iliac spine and the pubic tubercle by palpation and make an incision in the skin crease at the midpoint between these landmarks. Divide Camper fascia and Scarpa fascia. External oblique aponeurosis in the direction of the external ring, taking care to protect the ilioinguinal nerve that runs beneath (this step is operator depen­dent and does not have to be done in many settings). Identify and isolate the cord; divide cremasteric bers. Identify sac (lies anteromedial to cord structures) and separate sac from vas deferens and vessels without causing injury. Dissect hernia sac to the internal ring and ligate the sac without injury to the cord structures. A 3 mm laparoscope can be inserted through the hernia sac and secured with a tie; the peritoneal cavity can be insufated allowing for visualization of contralateral internal inguinal ring.
– Laparoscopic inguinal hernia repair
A 5mm laparoscope via the umbilicus. Females: A grasper inserted via stab incision can be inserted into the hernia and the hernia grasped and inverted. An endoloop placed via another stab inci­sion can then be used to ligate the hernia sac. Finally the endoloop and hernia sac are excised. Males: There are multiple different approaches to the hernia repair for males depending on the instru­mentation available. The ring is accessed via the skin overlying the internal ring; saline is injected in the plane between the peritoneum and vas/vessels. A suture is then placed circumferentially around the internal ring making sure to exclude the vas and vessels. The suture is then tied into the subcutane­ous tissues.
• Why would you choose open vs laparoscopic repair? – Data is limited comparing outcomes from open vs lap-
aroscopic. Both have associated risk of injury to vas
© The Author(s), under exclusive license to Springer Nature Switzerland AG 2025 M. Neff et al. (eds.), Passing the General Surgery Oral Board Exam, https://doi.org/10.1007/978-3-031-78244-2_123
423
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M. V. Butchy et al.
deferens, testicular atrophy, surgical site infection, and recurrence.
• What is the signicance of an absent vas deferens? – Absence of the vas deferens should prompt evaluation
for cystic brosis or unilateral renal agenesis.
• What is the timing of surgical repair in premature infants? – Decision to operate should be balanced with the risk of
incarceration and recurrence. Discussion with parents should include the balance of these risks.
– Patients with post-conceptual age of <60weeks have a
higher risk of postoperative apnea and need to be observed overnight.
– Premature infants also have a higher risk of recurrence
that is proportional to their age, so some advocate for later repair if the parents are reliable to bring the baby back in the case of incarceration.
• What are the most common operative complications? – Supercial surgical site infection (<1%) and recur-
rence of hernia (1–5%).
– Risk factor recurrence includes increased intra-
abdominal pressure, pre-op incarcerated hernia, pre­maturity, high ligation, and intraoperative injury to the inguinal canal oor.
– Most common intraoperative complication is injury to
the spermatic cord which can cause testicular atrophy (vessel injury) and future reproductivity (vas deferens).
• How do you differentiate between a hydrocele and a
recurrence?
– Physical exam can be helpful in assessing recurrence
vs uid accumulation postoperatively if you can feel a
fullness in the inguinal canal. – Ultrasound can be performed. – Fluid can resolve spontaneously or be aspirated.

Incarcerated Inguinal Hernia

Alternate Scenario
“A 3-month-old male presents with groin bulge and pain. The mom reports that she noticed a bulge in the patient’s scrotum when she was changing his diaper and he was cry­ing. Bulge is hard and tender to palpation.”
pressure to the apex of the hernia to reduce contents through the external ring.
• After successful reduction, what is the appropriate inter-
val to surgical repair?
– Straightforward reduction—no need for urgent repair. – Difcult reduction—consider repair in 24–72 h after
reduction to allow the edema to subside.
• What if you are unsuccessful in reducing incarcerated
inguinal hernia?
– Proceed directly to the operating room. This patient
population benets from laparoscopic repair because you can visualize the bowel after reduction and deter­mine the need for small bowel resection.
• What if there are signs of bowel ischemia or necrosis? – Incisions can be enlarged to assess and run the bowel.
If unable to adequately assess the bowel, laparoscopy or laparotomy should be performed to adequately assess the viability of the bowel.
• Long-term follow-up – Routine follow-up is typically limited to one ofce
visit for a wound check.

Clean Kills

• Failure to take an irreducible, incarcerated hernia to OR
urgently
• Failure to identify signs of bowel strangulation

Bonus Points

• Female inguinal hernias are most commonly incarcerated
with ovary instead of bowel. If suspected and conrmed on US, the patient with an incarcerated ovary with blood ow and no external signs of strangulation may be taken to the OR on a semi-elective basis. This is not a case that would require emergency surgical intervention in the middle of the night. If there are signs of strangulation, OR is necessary, and the ovary should be returned to the abdo­men unless frankly necrotic, in which case removal is necessary.
• How would you attempt to reduce an inguinal hernia? – Place patient supine in Trendelenburg position. Dim
the lights in the room. Pain control and sedation can increase the rate of reduction.
– Two-handed technique of taxis: Cranial hand applies
lateral and caudal pressure to the hernia to extend the aperture of the external ring. Caudal hand applies rm
Words ofWisdom
• Pediatric inguinal hernias can be difcult to diagnose. The differential diagnosis includes hydrocele, hernia, lymph nodes, abscess, ectopic testicle, etc. While US can be helpful in the diagnosis, dilated bowel may be difcult
123 Pediatric Inguinal Hernia
425
to differentiate from hydrocele, and one should always err on the side of caution proceeding the OR unless very con­dent in the diagnosis. Reduction is usually successful but may take time and patience. Lastly, always ensure that you can feel both testicles and are not missing an alternate diagnosis.

Bibliography

Holcomb and Ashcraft’s Pediatric Surgery. Sabiston Textbook of Surgery. SCORE.

Pediatric Appendicitis

M.VirginiaButchy, JohnWilliamson, andErikaB.Lindholm
124

Acute Appendicitis

Scenario
“A 10-year-old boy presents to the ED with fever, abdominal pain, nausea, and vomiting. The mom reports that the patient was not hungry at breakfast before school. Patient had mild abdominal pain and stayed home from school. Over the course of the day, the patient developed nausea and non­bloody, non-bilious vomiting. The pain migrated and local­ized to the right lower quadrant and became more severe prompting them to present to the emergency department this evening.”
• What lab work and imaging would you acquire? How
would this differ in a female patient?
– A complete blood count, a C-reactive protein, and
basic metabolic panel are commonly ordered. Patients typically have elevated WBC and CRP. Patients also often have a urinalysis sent to conrm that the urine is free of bacteria and red and white blood cells. It is not uncommon to see ketones in urine because patients are often dehydrated.
– Diagnostic imaging decreases the rate of negative
appendectomies.
Ultrasound utilizes no contrast or radiation. Can show a uid-lled, non-compressible appendix and a diameter>6 mm. Can also visualize an appendi­colith or periappendiceal or pericecal uid and inammation. It is very operator dependent.
M. V. Butchy · J. Williamson Department of Surgery, Cooper University Hospital, Camden, NJ, USA e-mail: butchy-margaret@cooperhealth.edu;
williamson.john@lha6.navy.mil
E. B. Lindholm ( Department of Surgery, Cooper University Hospital, Camden, NJ, USA
Division of Pediatric Surgery, Children’s Regional Hospital, Cooper University, Camden, NJ, USA e-mail: Lindholm-Erika@cooperhealth.edu
*)
Computed tomography is accurate and not operator dependent. Risk of malignancy with ionizing radia­tion to children. Often CT is utilized if ultrasound does not provide adequate information and MRI is unavailable. MRI is extremely accurate and does not expose children to radiation. Fast MRI uses two sequences to get the diagnosis in a short amount of time in the scanner. Unfortunately it is not always available and many children require sedation to undergo the scan.
• What is the role of nonoperative management of acute appendicitis with antibiotics?
– Few studies in pediatric patients but extensively stud-
ied in adult patients. Shows a relatively high success rate of initial nonoperative management (75–90%) with no increased risk of perforation, but recurrence rate is as high as 14%.
– Presence of appendicolith, abdominal pain >48 h,
WBC >18k, profound bandemia, CRP >4mg/dL, and signs of bowel obstruction or abscess are all adverse indicators for nonoperative management.
• How will you prepare the patient for the OR? How quickly
will you take the patient to the OR?
– Intravenous access should be obtained and the patient
should be started on intravenous uids. Patients should also be started on broad-spectrum antibiotics.
– Patients should be taken to the OR <24 h of initial
diagnosis. Acute, uncomplicated appendicitis is no longer an indication for emergent surgical interven­tion. Studies have shown no difference in the rate of perforation or postoperative abscess with delays of 12–24h.
• What surgery will you choose for this patient and why?
– Laparoscopic appendectomies are associated with
fewer wound infections and fewer small bowel obstruc­tions for adhesive disease.
– Laparoscopic appendectomies can be same-day surgi-
cal procedures.
© The Author(s), under exclusive license to Springer Nature Switzerland AG 2025 M. Neff et al. (eds.), Passing the General Surgery Oral Board Exam, https://doi.org/10.1007/978-3-031-78244-2_124
427