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Metals in Medicine, Volume 2
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Metals in Medicine, Volume 2: Metallic Nanoparticles for Biomedical Applications.
Sonali Sundram, Rishabha Malviya, and GSN Koteswara Rao
© 2025 Apple Academic Press, Inc. Co-published with CRC Press (Taylor & Francis)
Peculiarities of Blood Iron Balance
During Arterial Hypertension Recovery
According to the Centralized Aerobic–
Anaerobic Balance Compensation
SHISHONIN A. Y.
1
, ZHUKOV K. V.
1
, GASPARUAN B. A.
1
, and
VETCHER A. A.
1,2
1
Complementary and Integrative Health Clinic of Dr. Shishonin,
Moscow, Russia
2
CHAPTER 10
ABSTRACT
-
municable diseases (NCDs). According to the theory, the misinterpreting
containing protein, hemoglobin (Hb), is the major player in the oxygen-
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328
Metals in Medicine, Volume 2
10.1 [FE], [HB], AND NCDS
1 billion (2020) to 1.4 billion, and by 2050, 2 billion.
1
According to this, the
2
2,3
4
genesis anemia remains unclear.
5
4
-
-
6,7
FIGURE 10.1
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Peculiarities of Blood Iron Balance During Arterial Hypertension Recovery
329
10.2 A BRIEF OVERVIEW OF IRON ROLE IN HUMAN BODY
-
the blood.
8
-
9
strictly regulated. Such regulation creates a virtually closed system to iron.
and Fe
,
10
11
So, according to this
systemic levels.
12
9,13
Iron excre-
mammalian diet is strictly regulated. It occurs in the duodenum and only in
).
In dietary intake, iron can be present either in Fe
or Fe
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330
Metals in Medicine, Volume 2
9,13
In the proximal
through the
enterocyte membrane into the bloodstream once, and its synthesis takes
9,13
Iron transport
FIGURE 10.2
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Peculiarities of Blood Iron Balance During Arterial Hypertension Recovery
331
).
9,13
by endogenous
ascorbate, cysteine, and glutathione.
14
9,13
In blood
)
in various body environments does not exceed 10
-18
considered a normal level.
15
15,16
is 10
30
–9
8
15
17
In oxidative reac-
tions involving Fe
ions, ceruloplasmin is the main plasma antioxidant blood
17
-
tion.
9,13,17
9,13
and enters the transient pool only in an acidic medium.
9,13
12
), and this has a deep physiological meaning. In
in the cytochrome (Fe
respiration.
17
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332
Metals in Medicine, Volume 2
) state.
17
-
18
(Fig. 10.3).
FIGURE 10.3 Erythoid cell.
-
diseases, etc.
16,18
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Peculiarities of Blood Iron Balance During Arterial Hypertension Recovery
333
systemic iron homeostasis.
19
-
organisms.
20
physiological parameters, including erythropoietic activity during hypoxia,
20,21
• -
are the leading ones), leading to microcirculation disorders, hypoxia,
•
•
) in the body is completely
•
body or in all studied oxygen-dependent living beings.
10,13,16,21
in iron balance.
10.3 LIVER
metabolism in the body. It is hepatocytes that carry out the biosynthesis
22,23
binds blood iron.
24
25,26
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