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Файл:Ординатура / Хирургия / Библиотека им академика М.И. Перельмана / Книга_5672_Библиотеки_им_академика_М_И_Перельмана
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Metals in Medicine, Volume 2
silver ions released by the active galactic nucleus (AGN), inhibiting the
71
Xing et al. examined the silver-containing poly(3-hydroxybutyrate-co-
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-
72
One more study
73
Patrascu et al.
74
-lactide co-caprolac-
75
Due to
PCL.
74–78
Although bacteria can become immune to SNPs, according to
study.
79
generation and ion release are considered to have a limited role.
80
Given that GNP has bacteriostatic and bactericidal activity, it can be
81
Antimicrobials can attach to GNPs via covalent as
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Silver and Gold Nanoparticles for Tissue Engineering Application
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82
Bacillus cereus, Salmonella typhimurium, and Staphylococcus aureus
83
Applica-
84
laser combined therapy against Corynebacterium pseudotuberculosis bacteria
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C. pseudotuberculosis
production boosts cell oxidative stress in microorganisms, and results in the
-
-
thermal degeneration in the combined approach, GNP-laser. When exposed
C. pseudotuberculosis
85
-
-
lates to it,
86,87
dioxide, likely to result in hydroxyl groups, peroxides, and improved oxygen
concentrations that generate too many ROS and cause microbial destruction.
°
88
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greater biosecurity , and their uptake and metabolic activity can be controlled.
Compared to conventional antibiotics, gold nanostructures cause less micro-
bial resistance.
89
90
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91
antimicrobial against S. aureus and Escherichia coli, indicating that they
92
Human development and physiology depend on mechanotransduction,
at every level, including molecules, the entire body, organs, tissues, and
dystrophies, vascular and cardiac hypertrophy brought on by high blood
pressure, abnormal bone healing, and cell death.
93
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Silver and Gold Nanoparticles for Tissue Engineering Application
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94,95
17,96,97
For instance, a biode-
2
98
poly(N-isopropyl acrylamide)
17
pressure, gravity, acoustic vibration, actomyosin contraction, blood vessel
activities.
99–105
106
107
given that the mechanical
110
Additionally,
activated drug delivery system raises the possibility that such a system may
108
, SNPs caused extra-
the appropriate chemicals to cause cell death, demonstrating the apoptotic
be cautious about other cellular processes that can unintentionally change as
112–116
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technology, and that cell destiny can be controlled to regenerate and repair
117,118
mechanotransduction research are already employing nanotechnology and
119,120
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Sensitivity, selectivity, and multiplexing capability have been improved as
as labels in biomolecular detection. But in order to move these technologies
121
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glucose, adenosines, and hydrogen peroxide play crucial roles in assessing
122,123
In applications
124,125
synthetic tissue structures as biological substitutes to replenish, sustain, or
126
Cell-cell and cell-
127
Figure 7.3 displayed several biosensor applications.
FIGURE 7.3
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TABLE 7.2
Pros Cons
Short response time Expensive
Broad detection range
Portable
Small sample volume Stringent regulatory compliance
constraints.
124,128
physical characteristics.
129
130
NPs or nanocapsules
employing nanotechnology is the ability to distribute medications, trophic
131
132
Nanocantilevers,
133,134
135
Sensors can be divided
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Metals in Medicine, Volume 2
approaches: Electrochemical detection, optical detection, and electrical
detection are listed in that order.
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-
136
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nanomaterials because these materials can serve as both a recognition agent
and a transducer. Noble MNPs have received the most attention among all
-
teristics
137
and have been used extensively in the research and the creation
diagnostics that are more precise and sensitive. Generally , noble metals have
a remarkable ability to resist oxidation and corrosion even in a harsh envi-
ronment.
138,139
bacteria diagnostics.
140
140,141
a metallic nanostructure or rather induces a collaborative vibration is called
142,143
According to numerous reports, plasmonic applications have a promising
resolved.
144,145
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in numerous optical measurement systems.
146,147
Additionally, the NPs can
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adjustable.
148,149
150
selective, and multiplexable.
151,152
Nanosensors can be read out in a variety
153,154
Electrical recognition is a rapidly
processes
155
Numerous electrochemically based products are currently being
156,157
processing.
158
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impedance, a signal is produced.
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156
SNPs are also used same as
sensitivity, selectivity, and stability are displayed by the sensors made using
this technique.
159–164
common laboratory-based assays. Lab-on-a-chip devices are seamless
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165–171
172
173
biomaterials, their high biocompatibility, and their excellent stability have
(III) ions
174
can be noted. According to certain research, SNPs have oxidation signals
-
tude and intensity,
175–177
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certain applications. Additionally, some electrochemical reactions can be
166
keeps stable biomolecules biologically active. Studies reveal that NPs are
178
7.3 CHALLENGES AND FUTURE PERSPECTIVES
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reliant on disclosure and dose paradox. Nanostructures are employed in a
countless merchandise on the market that contain NPs or nanomaterials,
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