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Файл:Ординатура / Хирургия / Библиотека им академика М.И. Перельмана / Книга_5672_Библиотеки_им_академика_М_И_Перельмана
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Metals in Medicine, Volume 2
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an insulin-sensitive glucose transporter and is mostly present in adipose tissue
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use glycogen to store energy. In diabetic patients, inadequate insulin prevents
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25
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inhibit murine intestinal glucosidase.
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microRNA (miR)-103. Studies have revealed that obese mice and diabetic
in miR-143 and miR-103 expression. Other miRNAs control insulin resis-
could control other miRNAs.
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noma RIN-5F cells against oxidative injury brought on by hydrogen peroxide.
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Metals in Medicine, Volume 2
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based on antimetabolites, alkylating chemicals, bioactive natural compounds,
etc. Additionally, because those treatment plans are unable to distinguish
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cancer types has been discussed here (Fig. 4.3).
FIGURE 4.3
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31
Gracilaria
edulis aqueous extract on cervical cancer cell lines (SiHa). When SiHa cells
Additionally , they noticed that ZnONPs led to both necrosis and mitochondria-
dependent apoptosis in SiHa cells. AbuMousa et al. in 2020,
32
investigated
the WO
3
photocatalytic anticancer activity against cervical cancer cells (HeLa cells).
3
on the time approach. At the maximum concentration, the nanocomposites
Fakhroueian et al. in 2018,
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34
investigated the anticancer properties
nanoparticles caused apoptosis in MCF-7 cells and decreased their migratory
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Metals in Medicine, Volume 2
Wu et al. in 2019
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-
Haitao et al.
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Euphorbia
fischeriana
proteins that promote and inhibit apoptosis and increased oxidative stress,
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ROS. Elje et al. in 2020,
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50
2
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Jevapatarakul et al. in 2020,
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-
Cratoxylum formosum leaves crude extract (sheet-like
∼500 nm and spherical shape ∼
-
Priyadharshini et al. in 2014,
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41
revealed that
cells died. Using Hyssop (Hyssopus officinalis
al. in 2020,
42
early and late stages in the PC3 cell line, depending on the dose (4.88–6.25
Bai et al. in 2017,
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Metals in Medicine, Volume 2
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ined by Padmanabhan et al. in 2019,
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oxide nanoparticles (polygonal and 50 nm) and short hydrophobic peptides
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cells, the peptide-conjugated ZnONPs displayed more cytotoxicity. Majeed
et al. in 2019,
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in 2018,
47
because oral cancer is the most prevalent cancer in the oral maxil-
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mL as the IC50 value and demonstrated dose-dependent cytotoxicity (5–100
about by ZnONPs resulted in a reduction in mitochondrial membrane poten-
autophagy.
Namvar et al. in 2016,
48
examined in human acute promyelocytic leukemia
oxide nanoparticles (polygonal and 3–8 nm) by the hyaluronic acid (HA)
Sargassum muticum
also examined by Soni et al. in 2017.
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ZnONPs produced DNA damage,
as the LC50 value.
Altunbek et al. in 2018,
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conjugate the mainly prevalent blood proteins,
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Metals in Medicine, Volume 2
Namvar et al. in 2016,
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Sargassum muticum on
human pancreatic adenocarcinoma (Panc-1) cell line. Zinc oxide nanopar-
Zhao et al. in 2018,
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Anacardium occidentale
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agents and ZnO-NPs have also been used in vivo and in vitro, providing
investigated by Jiang et al.
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cells, demonstrating that these ZnO nanostructures had entered the cells
Zinc oxide nanoparticles can be chosen as an antibacterial substance due to
.
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the bacterial cells to die.
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Acinetobacter
baumannii
such as meningitis and pneumonia, Ghasemi and Jalal
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researched ZnO
Mycobacte-
rium tuberculosis
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produced
Mycobacterium tuberculosis
et al.
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