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Файл:Ординатура / Хирургия / Библиотека им академика М.И. Перельмана / Книга_5672_Библиотеки_им_академика_М_И_Перельмана
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Metals in Medicine, Volume 2
physiologically active molecules served as capping and reducing agents. As a
result, this strategy is better than the traditional ones.
62
and NaHCO
3
100 nm by an electrochemical–thermal method.
63
Materials can be precisely
deposited via atomic layer deposition at the atomic level. Numerous appli-
cations, including magnetic recording, sensors, and medication delivery in
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FIGURE 3.4
nanoparticles.
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Zinc Oxide Nanoparticles in Disease Diagnosis
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Due to its extraordinary electrical, optical, mechanical, magnetic, and
-
tigation over the past several years.
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morphology, orientation, and ratio, ZnO exhibits unique properties such as
structure-dependent electrical and thermal transport capacities.
66
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niques, it is important to consider the shape-related physical and chemical
48
Due to its unique physical and chemical properties, such as its high photo-
-
tromechanical nanodevices, sun screen lotion (cream), antibacterial agent,
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applications because they can easily pass through blood bank barriers, such
as ZnONPs.
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Metals in Medicine, Volume 2
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72
3.4 ZINC OXIDE NANOPARTICLES (ZnO NPS) IN DISEASE DIAGNOSIS
physiological and pathological processes that take place on a Nano scale
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and thermal transport properties that can vary according to the particle
66
ZnO NPs. Based on its anticancer, antibacterial, drug delivery, antidiabetic,
believed that ZnO NPs smaller than 100 nm are reasonably biocompatible,
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Zinc Oxide Nanoparticles in Disease Diagnosis
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TABLE 3.2
ZnO NPs.
Nanoparticle
morphology
Precursor used Method of
synthesis
Characterization
technique
Applications References
Zinc oxide
Nano spheres
Yeast extract
Zinc acetate
method
XRD
Inducing oxidative stress by increasing lipid
peroxidation and reactive oxygen species (ROS)
73
Zinc oxide
nanosheets
99.5, methanol, ammonia,
solvothermal
process
XRD, SEM Used as ethanol sensor 74
Zinc oxide
nanorods
SnO
2
and ZnO -
tion (vapor phase
method
Material
photo detectors, sensors, intra-molecular p–n
junction diode, and Schottky diode devices
75
Zinc oxide
Nano comb
transport method
SEM, XRD,
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Zinc oxide
Zinc acetate dehydrate,
sodium bicarbonate,
Nutrient media and B.
licheniformis
Microbial method
(B. licheniformis
contaminant
77
Zinc oxide
anoneedles
Si(111 substrate, ZnO
evaporation
spectrophotometer
78
Zinc oxide
nNano-
pyramid
oxygen
phase deposition
SEM, XRD
79
Zinc oxide
nanocrystals
Zinc nitrate,
hexamethylenetetramine
hydrothermal
method
FESEM -
optoelectronics
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Metals in Medicine, Volume 2
FIGURE 3.5
photo physical characteristics.
66
Recently, in vivo and in vitro biomedical
biophysics, proteomics, drug development, illness diagnostics, and environ-
mental investigation. ZnO Nano Rods (ZnO NR) systems have demonstrated
biomedical detection in both laboratory and clinical settings.
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ZnO NPs can
cancer, toxoplasmosis, and diabetes at the very early stage so that accurate
medications can be provided to the patients, and may not let the disease
progress to the next level.
3.5 ZnO NPS IN DIAGNOSIS OF ALZHEIMER’S DISEASE
understood, but a solution has not yet been discovered. Only an extremely
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Zinc Oxide Nanoparticles in Disease Diagnosis
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loss and cognitive decline and may subsequently impact behavior, speech,
visuospatial orientation, and the motor system.
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According to the amyloid cascade hypothesis, amyloid-beta-deposits
-
-
tory mediators that may damage the brain, such as reactive oxygen and
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Amyloids,
-
-
ders. Biochemical methods such as ELISA and mass spectrometry (MS)
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Metals in Medicine, Volume 2
the initial stage to get over these constraints. ZnO NPs are a dependable
-
this chapter, a semiconductor nanocrystal that may be used as a dual-color
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amyloid that are undetected by traditional techniques.
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the theory that ZnO nanoclusters are created in vivo during the biosynthesis
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3.6 ZNO NPS IN DIAGNOSIS OF CANCER
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19.3 million cases and 10 million cancer deaths in 2020. More than 100
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Healthy cells respond
cancer as cancerous cells have metastatic properties.
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Metals in Medicine, Volume 2
techniques that are based on cell shape and use staining and microscopy.
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disease. More study is required to create tests that can detect malignancy
cancer biomarkers. Some ELISA tests are also not sensitive enough to detect
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medical procedures, including cancer diagnostics.
and in vitro during skin penetration.
97,98
cervix, and leukemia.
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oxide glass substrate, and covalently bond them to anti-ErB2 (epidermal
immunosensors demonstrated exceptional sensitivity, stability, reproduc-
-
98–100
Lip, oral cavity , and oropharynx tumors are all considered to be oral malignan-
been claimed that eating betel nuts in certain communities is linked to mouth
and mouth cancer are visual inspection and biopsy (such as leukoplakia and
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