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Part XXVIII
Renal Artery Stenting
Renal Artery Stenting forRenal Vascular Hypertension inaPatient withSolitary Kidney
History andPhysical Examination
A 52-year-old male was referred by his nephrolo­gist in October 2014 for possible renal artery stenting for uncontrolled hypertension. Patient has history of hypertension for the past 10years and had undergone laparoscopic nephrectomy in 2012 for atrophic kidney secondary to renal artery occlusive disease. He was on four blood pressure medications (amlodipine, metoprolol, hydrochlorothiazide, and clonidine). Patient underwent MRA in 2002 which showed occlu­sion of the right renal artery (Fig.98.1). Patient underwent renal duplex study which showed normal- size left kidney with greater than 70% stenosis of the left renal artery in September
2014.
98

Procedure

Patient underwent abdominal and renal arterio­gram in October 25, 2014, via right femoral artery approach using micropuncture technique with insertion of a 5F sheath. Using Omniush catheter (AngioDynamics, Latham, NY) over an angle stiff GLIDEWIRE® (Terumo, Tokyo, Japan), 180-cm-long 035mm aortogram showed slight aneurysmal dilatation of the abdominal aorta and 80% stenosis at the origin of the left renal artery (Fig.98.2). A 5F sheath was replaced with a 6 F 45 cm angled Pinnacle sheath
© Springer Nature Switzerland AG 2020 S. S. Hans, Challenging Arterial Reconstructions, https://doi.org/10.1007/978-3-030-44135-7_98
Fig. 98.1 MRA showing right renal artery occlusion
(Terumo). Using SOS Omni catheter (AngioDynamics) and a soft Glidewire 0.35 180cm was advanced into the upper pole branch of the left renal artery. Glidewire was exchanged for 180-cm-long 035 Magic Torque wire, and long sheath was advanced near the origin of the left renal artery. A 6×19mm Omnilink (Abbott, Abbott Park, IL) balloon expandable stent was
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450
98 Renal Artery Stenting forRenal Vascular Hypertension inaPatient withSolitary Kidney
advanced through the sheath. The sheath was retracted, and the stent was deployed with 2mm of the stent projecting into the lumen of the aorta. 14 atmospheric pressure was used for ination of the balloon so that the nal diameter of the stent was 6.4cm (Fig.98.3). Patient was followed for
1.5 years with no evidence of recurrent stenosis
Fig. 98.2 Abdominal aortogram showing greater than
80% left renal artery stenosis
with better control of blood pressure. Follow-up duplex imaging of renal artery showed satisfac­tory peak velocity in November 2014 and in June
2015.
However, in June 2016, renal artery duplex imaging showed greater than 70% left renal artery stenosis with elevation of serum creatinine from 0.9 to 1.2 mg/dL. Patient underwent left renal artery angioplasty for in-stent restenosis (greater than 70%) via percutaneous left brachial artery approach using exchange length glidewire 260-cm-long 035 and using a 6 F 90-cm-long sheath. A 6mm × 2-cm-long balloon was used (Fig. 98.4). The procedure was performed on July 6, 2006. During the later part of the proce­dure, patient developed left ank pain associated with nausea and became diaphoretic. Patient underwent CT scan of the abdomen which showed large subcapsular hematoma of the left kidney with small retroperitoneal hemorrhage (Fig. 98.5). Patient was treated conservatively, and his symptoms resolved in 6 hours, and he was discharged after a 24hour stay from the hos­pital. Patient was last seen in December 2019 with a serum creatinine of 1.2mg/dL with a nor­mal left renal duplex scan and better control of blood pressure.
Fig. 98.3 Aortogram following renal artery stenting

Discussion

Fig. 98.4 Renal angioplasty via a brachial approach for in-stent restenosis
hypertension, and ischemic nephropathy and unresponsive to medical therapy are most likely to benet from renal artery revascular­ization [1].
The result of CORAL (Cardiovascular Outcomes in Renal Atherosclerotic Lesions) trial has signicantly decreased the indication for renal angioplasty (stenting) for atheroscle­rotic renal artery stenosis. The CORAL trial did not show a statistically signicant reduction in blood pressure following renal angioplasty/ stenting when compared with best medical man­agement. Studies evaluating the use of renal angioplasty/stenting for preservation of the renal function have been even less promising
Fig. 98.5 CTA showing left renal subcapsular
hematoma
with no advantage for renal intervention but with a possibility of access-related complication [1]. Subgroup analysis of CORAL trial failed to identify severity of blood pressure as good pre-
Discussion
dictors of response to stent treatment. The one baseline variable that appears promising for pre-
Atherosclerotic renal artery stenosis accounts for greater than 90% cases of renal artery ste­nosis and most often presents in patients greater than 65years of age [1]. It may be an independent predictor of death in patients for coronary artery disease [1]. Patients with car­diac destabilization syndromes, renal vascular
dicting a favorable response to stent interven­tion is the urine albumin to creatinine ratio with a low UACR (urine albumin-to-creatinine ratio) portending a favorable response [2]. In this patient with uncontrolled blood pressure with severe renal artery stenosis in a solitary kidney, it was nephrologist’s opinion that renal stenting
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98 Renal Artery Stenting forRenal Vascular Hypertension inaPatient withSolitary Kidney
should be performed. Patient did develop com­plication of periprocedural renal subcapsular hematoma. Therefore, the benets of renal stenting with renal vascular hypertension and preservation of renal function must be weighed against the complications of intervention. At present, renal artery stenting should be infre­quently performed [3]. However, renal artery stenting may need to be performed during or following endovascular aneurysm repair in select group of patients [3]. In contemporary practice there are few indications of renal artery stenting, and patient should be very carefully selected with close consultation with nephrolo­gist. Primary patency of renal artery stenting exceeds 80% at 5years, and surveillance for in-
stent restenosis should be done with renal duplex imaging on a yearly basis [1].

References

1. Tafur JP, White CJ. Renal artery stenosis went
to revascularize in 2017. Curr Probl Cardiol.
2017;122:110–35.
2. Gupta R, Assiri S, Cooper CJ. Renal artery stenosis
ndings from the CORAL trial. Curr Cardiol Rep.
2017;19(9):75.
3. Alexander JQ, Green D, Sullivan TM.Endovascular
intervention for renal artery occlusive disease. In:
Hans SS, Shephard AD, Weaver MR, Bove PG, Long
GW, editors. Endovascular and open vascular recon-
struction: a practical approach. Boca Raton: CRC
Press; 2018. p.19–25.
Part XXIX
Subclavian Artery Stenting
Subclavian Artery Stenting forIschemic Left Index Finger
99
Physical Examination andHistory
A 48-year-old female was admitted to the hospital in October 2018 with pain and cyanotic discolor­ation of the ngers of the left hand more marked in the left index nger. There was associated cool­ness and paresthesia of the hand. The symptoms started 2weeks prior to admission (Fig.99.1). She
Fig. 99.1 Cyanotic discoloration of the left index nger
had history of nicotine abuse (60 pack years). On examination, left axillary brachial and radial pulses were absent. Upper extremity arterial Doppler study showed a wrist brachial index of
1.0 on the right and 0.68 on the left. CTA of the upper extremities showed near occlusion of the left subclavian artery 1.5cm from its origin with reconstitution of the artery beyond the stenosis. Left vertebral artery was smaller in caliber as compared to the right.

Procedure

Patient underwent left subclavian artery stenting on October 10, 2018, via left brachial artery cut­down. Using a small transverse incision, brachial artery was looped with a silastic loop, and a 5F sheath was inserted into the small diameter bra­chial artery (Fig. 99.2). An Omniush (AngioDynamics, Latham, NY) marker catheter was advanced over 180-cm-long angle stiff GLIDEWIRE subclavian arteriogram was obtained which showed severe stenosis of the left subclavian artery
1.5cm from its origin (Fig.99.3). A 5F sheath was exchanged for a 6 F sheath and 45-cm- long Pinnacle sheath (Terumo), and pre- angioplasty with a 6 mm × 2-cm-long Armada® balloon (Abbott, Abbott Park, IL) was performed followed by deployment of an 8×17mm balloon expand­able stent (Fig. 99.3). Completion run showed
®
(Terumo, Tokyo, Japan), and a left
© Springer Nature Switzerland AG 2020 S. S. Hans, Challenging Arterial Reconstructions, https://doi.org/10.1007/978-3-030-44135-7_99
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99 Subclavian Artery Stenting forIschemic Left Index Finger
Fig. 99.2 Aortogram via left brachial approach showing
severe stenosis of the left subclavian artery
Fig. 99.3 Post-stent angioplasty of the left subclavian
artery stenosis
excellent result (Fig. 99.4). Brachial artery was sutured with interrupted 7-0 cardiovascular poly­propylene suture (Ethicon Inc., Somerville, NJ). Patient had marked improvement in her symp­toms, and ischemic changes in the nger resolved during subsequent 6weeks (Fig.99.5). Patient had easily palpable left brachial and radial pulse. Wrist brachial index was normal on both sides (1). She was seen at follow- up on March 2019 without any symptoms in her left hand.
Fig. 99.4 Completion run with minimal residual stenosis
with robust lling of the left vertebral artery
Fig. 99.5 Complete resolution of cyanotic discoloration
of the hand (nger)

Discussion

The subclavian artery is the most frequent inter­vened on in the brachial cephalic distribution. Open surgical bypass has excellent outcomes but carries signicant morbidity and even mortality [1]. Therefore, endovascular therapy has become the rst-line consideration for treatment of sub­clavian artery lesions especially as patency rates have continued to improve and are reported to be

Reference

457
>90% secondary patency at 1 and 5 years [1]. Although femoral access is the preferred approach to subclavian artery lesions, brachial access is an important access site to subclavian artery interventions. Brachial artery approach is preferable for crossing the occlusions involving the origin of the subclavian artery as introduction of the catheter into the origin of the subclavian artery from the aortic arch in these situations may not be always feasible. One other consideration regardless of the vessels involved from the aortic arch branches is the relative location of other ves­sel origins. In patients with major branch origins located very close to one another, expose the other vessels for risk during intervention, espe­cially in a heavily calcied lesion [1]. In these circumstances, disruption of the calcium during the intervention can result in shift of the calcied lesion leading to compromise of the lumen of the
adjacent vessel. This should be evaluated with preoperative CTA or an evaluation performed during the performance of arch aortogram [1]. In order to protect the adjacent vessel origin, a bal­loon can be inated during the intervention [1]. This may require cannulation through an ancil­lary access or placement of a buddy wire via femoral access [1]. The protective balloon should be slightly undersized to the vessel diameter in order to avoid vessel trauma during ination [1].
Reference
1. Sullivan TM, Titus JM.Stenting for occlusive disease
to the aortic arch branches. In: Hans SS, Shephard
AD, Weaver MR, Bove PG, Long GW, editors.
Endovascular and open vascular reconstruction: a
practical approach. Boca Raton: CRC Press; 2018.
p.9–18.
Part XXX
Acquired Arteriovenous Fistula