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improved function of product, decreased 24-hour and in-hospital mortality, and decreased compli­cation rates [12, 20, 21].
Traumatic Brain Injury (TBI)
The initial evaluation of polytrauma patients with suspected TBI should prioritize the assess­ment of neurological status. The Glasgow Coma Scale (GCS) remains a valuable tool for quanti­fying the severity of TBI.The goal of preventing secondary injury in traumatic brain injury (TBI) is a crucial focus of evidence-based manage­ment. It is one of the major effects clinicians can have to prevent worsening of patient outcomes. The two major and preventable causes that are seen to cause secondary injury are hypoxia and hypotension.
Maintaining adequate cerebral perfusion pres­sure (CPP) by optimizing blood pressure and oxygen delivery to the brain is essential. Cerebral perfusion pressure = mean arterial pressure­ICP. Current guidelines support the use of advanced monitoring techniques to guide the management of TBI in polytrauma patients [22]. Intracranial pressure (ICP) monitoring is crucial for early detection and management of intracra­nial hypertension, which can lead to secondary brain injury. Classical recommendations per the Brain Trauma Foundation recommend maintain­ing an ICP of 22. However, more recent studies suggest that a patient specic ICP goal is more correlated with improved outcomes [23, 24]. There has recently been questioning if agents like hypertonic saline or mannitol are benecial. While they have been shown to decrease ICP, there appears to be no benet in mortality or neu­rological outcome with them [2527].
Two recent randomized control trials evalu­ated the utility of using prophylactic hypothermia in severe TBI. They differed slightly with one using hypothermia in patients with elevated ICP and the other study performed this in patients without elevated ICP [28, 29]. While prophylac­tic hypothermia was successful at decreasing ICP, but at the cost of increased mortality and worst neurological outcomes [28, 29]. Further, patients with TBI that present with accidental
hypothermia are found to have signicantly higher rates of mortality [30].
Surgical Interventions: In select cases of severe TBI, surgical interventions like decom­pressive craniectomy have gained prominence as a means to reduce intracranial pressure and pre­vent herniation. Some data suggests that use of decompressive craniectomy can improve out­comes, particularly in patients with refractory intracranial hypertension [31, 32]. In contrast, the DECRA study showed while early decompres­sive craniectomy decreased intracranial pressure, it was associated with worst 6-month mortality [33]. However, the correct patients that would benet most from decompressive craniectomy and have meaningful quality of life are still being investigated. Hypoxia and hypotension are associated with poorer outcomes in TBI patients, emphasizing the importance of oxygenation and hemodynamic stability. Addressing injuries that cause hemody­namic instability becomes a priority in patients with TBI. Additionally, avoiding hypercapnia and maintaining normocapnia, as well as manag­ing temperature to prevent hyperthermia, have been shown to reduce secondary injury. Close neurological monitoring, the use of advanced neuromonitoring techniques, and a multidisci­plinary approach are integral to the evidence­based prevention of secondary brain injury in TBI patients.
Abdominal Injuries
Damage Control Laparotomy
Damage Control Laparotomy (DCL) continues to be a fundamental part of trauma surgery. DCL focuses on controlling hemorrhage and contami­nation while minimizing operative time to save the physiologic reserve of the patient. Typical indications for DCL are as follows: metabolic acidosis (pH<7.2), hypothermia (<35°C), coag­ulopathy, patients who are unstable and operation will last longer than 2hours, or patients that will require further intra-abdominal surgical evalua­tion at a later time [34].
22 Surgical Decision-Making intheManagement ofPolytrauma Patients
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Combination of improvements in temporary abdominal closures and hemostatic resuscitation over the past decade have made the DCL more efcient and decreased the rate of complications we see. As stated above the focus of DCL is rst controlling hemorrhage and second, contamina­tion. Hemorrhage should be controlled with timely repair, packing, simple ligation, or tem­porary shunts. Hollow viscus injuries should be resected and anastomosis left for the time of denitive repair. Multiple different methods of temporary negative pressure systems exist com­mercially or can be fashioned with equipment readily available in the operating room, to serve as an optimal method of temporary abdominal closure. The initial portion consists of a porous plastic covering that allows extraction of uid while preventing the formation of adhesions. In authors’ experience, a sterile X-ray lm cover with perforations works very well, is inexpen­sive and readily available. Foam or operating room sterile towels are then placed with an even­tual occlusive dressing overtop with airtight drains being laid in bilateral gutters. Negative pressure is then typically applied between 100 and 150mmHg. There are also readily available commercial products that include all parts in a single package. Once the patient has been removed from the operating room, focus should be placed on further resuscitation, hemodynamic stability, correction of acid/base, electrolyte abnormalities and rewarming.
After the patient has been stabilized and phys­iologically optimized in the ICU setting, they should be considered for return to the operating room either for repeat exploration or denitive repair. While multiple centers and surgeons will opt for an arbitrary 48-hour period, we recom­mend returning to the operating room once the patient is physiologically optimized.
With the evolution of and utilization of the open abdomen strategy, it is important to keep in mind closure of the abdomen. Delay in closure is associated with increase in ventral hernias, enterocutaneous or entero-atmospheric stulas, and loss of abdominal domain. One recent study showed that closure of the abdomen within 8days can minimize complications [35].
Non-operative management
High quality data shows the benet of non­operative management (NOM) within abdominal trauma in certain clinical situations [36, 37]. The current standard of care for the majority of patients with blunt abdominal trauma who are hemodynamically stable without peritonitis is to pursue further radiological work up with com­puted tomography. However, patients who are hemodynamically unstable or exhibit peritonitis on examination should undergo surgical inter­vention, as stated above.
The management of transient responders involves institutional resources (availability of interventional radiology or surgical capabilities) to address the cause of hemodynamic instability. In facilities with quick access to interventional radiology, stable patients with solid organ inju­ries of advanced grading will often be effectively treated with angioembolization or other interven­tional radiologic interventions. Our institution uses the American Association for Surgery of Trauma grading of solid organ injuries.
Patients with known injuries who are being managed with NOM require hospital admittance with close monitoring for changes in the patient’s clinical status. There are no current recommenda­tions on the frequency of monitoring; however, it typically consists of serial laboratory values, NPO status, initial short-term limitations of activ­ity, and repeat abdominal examinations. Clinicians also need to maintain a high index of suspicion for injuries that are often missed on the patient’s initial CT scan, including hollow viscus injuries and diaphragmatic injuries. Furthermore, patients who experience deterioration in their clinical status should undergo operative interven­tion as quickly as possible.
Thoracic Injuries
Injuries resulting from trauma stand as the pri­mary global cause of mortality. In the United States, thoracic trauma contributes to as much as 35% of trauma-related fatalities, involving a diverse array of injuries resulting in signicant morbidity and mortality [38, 39]. Thoracic trauma is seen in approximately two-thirds of trauma patients and with varying degrees of severity,
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often ranging from simple rib fractures to more complex penetrating injuries. Thoracic trauma is broadly categorized as blunt or penetrating trauma. Blunt chest trauma is the most common, accounting for 80% of incidents, with less than 10% needing any form of surgical intervention vs. 15 to 30% in patients that sustained penetrating chest injuries [38]. However, blunt chest trauma directly contributes to 20 to 25% of trauma deaths [38]. Mortality rates, second only to head injuries, emphasize the critical signicance of prompt and effective initial management. Timely diagnosis and treatment can prevent a signicant number of these fatalities [38].
The management of chest trauma can be cate­gorized into three specic tiers of care: prehospi­tal trauma support, in-hospital or emergency room trauma support, and surgical trauma sup­port [36]. Recognizing thoracic injuries at each care level is pivotal for subsequent outcomes. The initial resuscitation and management of a patient with chest trauma adhere to protocols out­lined in Advanced Trauma Life Support (ATLS) [5]. Following a primary survey, the focus is on promptly excluding or addressing immediately life-threatening injuries, such as tension pneumo­thorax, massive hemothorax, ail chest, cardiac tamponade, aortic injury, and tracheobronchial disruption.
Prehospital support: The initial evaluation of the trauma patient begins with the primary survey, which is an essential step in recogniz­ing immediately life-threatening conditions such as tension pneumothorax, pulmonary con­tusion, massive hemothorax, and cardiac tam­ponade. General inspection of the thorax for asymmetry; palpation for tenderness, crepitus, and ail segments; percussion; and ausculta­tion [sensitivity of 90% and specicity of 98% will aid in identifying life-threatening condi­tions such as tension pneumothorax, which may necessitate immediate intervention such as needle decompression or tube thoracostomy [40, 41]. Given that tension pneumothorax stands as the most frequently reversible cause of death in trauma patients experiencing car­diac arrest, prompt and accurate assessment is crucial [4244].
In-hospital support: The assessment of patients with thoracic trauma commences with Advanced Trauma Life Support (ATLS) and sub­sequently utilizes diverse imaging methods con­tingent on the initial symptoms observed. Swift intervention is imperative for life-threatening injuries identied during the initial trauma assessment.
Ever since its initial formal description nearly ve decades ago, the emergency department tho­racotomy (EDT) has remained a subject of debate for many years [45]. Research indicates that out­comes depend on the mechanism of injury, ana­tomic location of injury, and the presence of signs of life on arrival [39]. Dened by the American College of Surgeons Committee on Trauma in 2001, signs of life are considered present with any of the following: pupillary response, spontaneous ventilation, presence of carotid pulse, measurable or palpable blood pressure, extremity movement, or cardiac electrical activity [45]. In penetrating chest trauma, the survival rate after resuscitative thoracotomy is 8.8%, contrasting with 1.4% in blunt chest trauma. Notably, patients with pene­trating chest trauma and signs of life upon arrival have an overall survival rate of 19.4% in contrast to 4.6% overall survival in blunt chest trauma with signs of life present upon arrival [46]. There have recently been some suggestions as to differ­ent indications in pediatric patients compared to adult patients [47, 48]. Adult and pediatric patient indications/contraindications for resuscitative thoracotomy include [4951]:
Adult Indications:
Salvageable postinjury cardiac arrest:
• Patients sustaining witnessed penetrating
trauma with <15minutes of prehospital CPR.
• Patients sustaining witnessed blunt trauma
with <5minutes of prehospital CPR.
Persistent severe postinjury hypotension (SBP60mmHg) due to:
• Cardiac tamponade.
• Hemorrhage—intrathoracic, intra-abdominal,
extremity, cervical.
• Air embolism.
22 Surgical Decision-Making intheManagement ofPolytrauma Patients
283
Adult Contraindications:
• Penetrating trauma: CPR>15minutes and no signs of life (pupillary response, respiratory effort, or motor activity).
• Blunt trauma: CPR>5minutes and no signs of life or asystole.
Pediatric Indications:
• Pediatric patients with penetrating thoracic or abdominopelvic injury and signs of life on presentation.
• Pediatric patients with blunt injury and signs of life on presentation.
Pediatric Contraindications:
• Pediatric patients with penetrating thoracic or abdominopelvic injury without signs of life on presentation.
• Pediatric patients with blunt injury without signs of life on presentation.
Hemothorax and pneumothorax are the most
common injuries frequently encountered in tho­racic trauma. These can be denitively managed through the use of a chest tube in 80% of cases [39]. Approximately 10% of all trauma patients and 30% of those with chest trauma exhibit rib fractures [43]. Initial management in patients with three or more rib fractures entails ensuring ade­quate analgesia, thoracostomy drainage if required, and pulmonary hygiene. Effective pain control is paramount and involves a multimodal approach beginning with acetaminophen and NSAIDs, with opioids administered on an as­needed basis. Regional anesthesia, such as epi­dural anesthesia can be used as a step-up approach for patients with multiple or displaced rib frac­tures, and for those with pain unresponsive to pharmacologic management [45]. Surgical rib xation is typically performed within 48 to 72 hours of the injury and is reserved for cases where adequate pain control cannot be achieved and for patients facing impending respiratory fail­ure or unable to wean off ventilatory support [39].
Certain patients require urgent or emergent oper­ative intervention. Thoracotomy performed in the operating room is indicated for various condi­tions in thoracic trauma including massive hemo­thorax with blood loss 1500 mL initially or > 200 mL/hour of chest tube output over 2–4 hours, cardiac tamponade, great vessel injury, signicant air leak persisting after thora­costomy placement, conrmed tracheobronchial injury, and open pneumothorax [34]. As mini­mally invasive techniques have become more popular, video-assisted thoracoscopic surgery (VATS) has been increasingly used in favor of thoracotomy in hemodynamically stable trauma patients, leading to faster recovery, reduced post­operative pain, and greater visualization of the entire pleural place for diagnosing and treating commonly missed injuries such as retained hemothoraces and diaphragmatic lesions [38, 52,
53].
Orthopedic Management
Orthopedic injuries are a signicant source of hemorrhagic shock and blood loss for poly­trauma patients and must be considered and addressed in the acute setting. It has been esti­mated that a signicant amount of musculoskel­etal injuries are missed during the primary survey [54].
Pelvic fractures can cause a signicant amount of blood loss without external physical signs other than vital changes. Open long-bone frac­tures also must be recognized and addressed as they have major vascular supply and will have no means of self-tamponade. Orthopedic trauma surgery has also taken a similar paradigm shift from what was previously known as “Early Total Care” (ETC) to what is now standard of care as “Damage Control Orthopedics” (DCO). The notion that the polytrauma patients with signi­cant musculoskeletal injuries were considered too physiologically unstable to undergo any major orthopedic surgery was questioned by the Bone et al. study in 1989 [55]. This landmark study found that early xation of all long-bone fractures within 24hours of initial injury led to reduced morbidity among patients, including
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reduced pulmonary complications and length of ICU and hospital stay [55]. The term “Early Total Care” was shortly established following this study, and it referred to denitive fracture surgery within 24–48hours for all long-bone fractures in a polytrauma patient. The practice of ETC was challenged as studies that followed found a rise in pulmonary complications and multiorgan dys­function observed in polytraumatized and physi­ologically unstable patients that were managed using this approach. The studies described these complications as arising from the “second hit” or inammatory response associated with fracture surgery [56]. This led to the emergence of “DCO.” Modeled after the concept of “damage control surgery,” “DCO” emphasizes that a cer­tain subgroup of patients require further resusci­tation and medical optimization prior to undergoing denitive fracture surgery and thus, temporizing measures such as external xation of fractures can lead to more favorable outcomes in such patient groups [57]. Current recommenda­tions though are for open fractures to be taken to the OR within 24hours for initially debridement and possible early closure [55].
Infection Prevention andAntibiotics
Prophylactic Antibiotics
Prompt antibiotic use is important in indicated clinical settings, while not overusing to create antibiotic resistance is also essential. The usage of antibiotics must still be driven by the etiology of disease process that the patient is experienc­ing. Patients who have open fractures, lacera­tions, or concern for viscus injuries justify the usage of antibiotics. The majority of trauma cen­ters will have intuitional protocols for recom­mended antibiotic and dosages given their area specic microbiome. Those who are being taken to the operating room for intervention also justify the use of prophylactic antibiotics given within one hour prior to incision. In regard to doing open abdomen, evidence shows that there is a benet in prompt prophylactic administration of antibiotics and early discontinuation in appropri­ate patients [58].

Multidisciplinary Care

Team Collaboration
The polytrauma patient often presents with inju­ries spanning various medical specialties, neces­sitating a comprehensive, multidisciplinary treatment approach. The optimal approach to car­ing for multiply injured patients requires a multi­disciplinary team, including but not limited to trauma surgeons, orthopedic surgeons, anesthesi­ologists, intensivists, neurosurgeons, maxillofa­cial surgeons, ophthalmologists, diagnostic/ interventional radiologists, and various other spe­cialists [59]. Vertical integration of various teams within the healthcare system is essential in the delivery of care and management of the poly­trauma patient. This includes integration of nurs­ing, advanced practice providers, pharmacists, blood bank, case managers, social workers, clini­cal psychiatry, and physical and occupational therapists to name a few.
This comprehensive approach to managing polytraumatized patients spans across various disciplines, commencing in the prehospital phase with the involvement of early responders and emergency medical service (EMS) personnel. It is these highly specialized prehospital teams who are tasked with the initial assessment, stabiliza­tion, and transportation of the polytrauma patient to the nearest trauma center equipped to address their needs [60]. Given the substantial volume of trauma patients, accurate triage is crucial, with over 90% best served inlocal community hospi­tals [60]. The remaining 10%, comprising severely injured individuals necessitating higher level of care at Level I and II trauma centers, demands a multidisciplinary approach to enhance overall clinical outcomes [60]. When in the trauma bay, effective, closed-loop communica­tion and level-appropriate division of tasks among members of the team is of crucial importance in effectively managing a polytrauma patient [61]. Team members such as anesthesiol­ogists play a major role in both the peri-operative and intraoperative care of the polytrauma patient. Ensuring that recommended large bore periph­eral IV access (or when not possible adequate vascular access, intraosseous needle, central
22 Surgical Decision-Making intheManagement ofPolytrauma Patients
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venous line, or arterial line for hemodynamic monitoring) has been obtained for resuscitation and infusion of intravenous uids, blood prod­ucts, and medications is a task that can be accom­plished by trained emergency room providers while the trauma surgeon can focus on the opera­tive management aspect of the patient. Once the patient has been stabilized, the intensivists not only provide additional critical care to trauma patients but are also intimately involved in con­sulting and coordinating care between different members of the healthcare team. Thus, success­ful integration of a collaborative, multidisci­plinary team approach in managing the polytrauma patient is crucial for minimizing complications, lowering mortality rates, and expediting recovery following injury [59].

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Decision-Making inComplex Dento-Alveolar Trauma intheMaxillofacial Region
LumnijeKqiku andKurtAloisEbeleseder
23

Introduction

General Remarks

Maxillofacial trauma, skull fractures, and dento­alveolar injuries are frequently found in blunt and penetrating trauma patients.
About 50% of isolated cases of traumatic den­tal injuries occur in children and teenagers, 19% in girls, and 33% of all boys are affected.
Dento-alveolar trauma has multiple etiologies including trafc collisions, sports injuries and falls, assaults, or industrial mishaps [13].
Proper decision-making on the treatment of dento-alveolar injuries is necessary to avoid seri­ous long-term morphologic, functional, and aes­thetic consequences. In addition to soft tissue injuries, dental trauma is the most common facial trauma in the maxillofacial region and primarily affects the anterior region of the teeth [47].
In clinical situations with polytraumatized patients showing multiple facial, orbital, and skull fractures, bleeding, dental avulsions, frac­tures of the alveolar process, intrusions, and severe intraoral soft tissue injuries, surgical
L. Kqiku (*) · K. A. Ebeleseder Department of Dental Medicine and Oral Health, Division of Restorative Dentistry, Periodontology and Prosthodontics, Medical University of Graz, Graz, Austria e-mail: lumnije.kqiku@medunigraz.at;
kurt.ebeleseder@medunigraz.at
decision- making is very important. The decision to perform denitive treatment during emergency or subsequently, once the major and high-risk injuries have been taken care and swelling has subsided, is a matter of intuition, patient’s physi­ology, and overall clinical status. Tooth avulsion, on the other hand, needs to be treated properly and immediately [8].
In fractures of the alveolar process, a quick decision should be made between manual reposi­tion/splinting and open surgery (Figs. 23.1 and
23.2).
This means that for complex trauma, early recognition of all injuries is necessary for the decision between closed treatment (nasal tam­pons, intermaxillary xation, rigid and exible splints for dental injuries) and open treatment (surgical intervention).
Facial fractures such as nasal bone fractures, naso-orbito-ethmoid complex fractures, orbital fractures, zygomaticomaxillary complex frac­tures, Le Fort fractures (Le Fort type 1,2,3), and mandibular fractures (body, symphysis mentalis, ramus, condyle, coronoid process, alveolar crest) are the most common injuries in maxillofacial emergencies. Dento-alveolar injuries are associ­ated with all types of facial trauma, and surgical decision-making should be guided by clinical scenario.
© The Author(s), under exclusive license to Springer Nature Switzerland AG 2024 R. Lati (ed.), Surgical Decision-Making, https://doi.org/10.1007/978-3-031-67391-7_23
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Figs. 23.1 and 23.2 Alveolar process fracture/manual reposition and splinting immediately after trauma
L. Kqiku and K. A. Ebeleseder
Classication ofDento-Alveolar Injuries
The most commonly used classication system for dental trauma is Andreasen’s classication (accepted by the WHO in 1972 and propagated by the International Association of Dental Traumatology, IADT) which is applied to both primary and permanent teeth [9]. It distinguishes between 4 types of fractures (crown fracture, crown root fracture, root fracture, and fracture of the alveolar process) and 6 types of luxations, respectively, dislocations (concussion, sublux­ation, lateral luxation, extrusion, intrusion, and avulsion).
This means that dento-alveolar injuries are described as syndromes. A more analytic classi­cation describes the tooth as composed of ve tis­sues that can also be injured independently from each other [10, 11]. Thus, any injured tooth is described in ve aspects: Dental Hard tissue, Endodontium, Periodontal ligament, Alveolar bone, and Gingiva.
By this method, also uninjured aspects are described automatically (Table23.1 depicts this classication).
Fracture injuries of the dental hard tissues comprise crown fracture, crown root fracture, and root fracture (Fig. 23.3), while the Endodontium (dental pulp) can be affected together with all forms of dento-alveolar injuries. It can be injured in the form of an indirect expo-
sure (dentin fracture), a direct exposure to the oral cavity, an internal exposure to the injured periodontal ligament (in root fractures), a strain, a contusion, or a separation (Fig.23.4). On the other hand, the Periodontium is affected in so- called Luxation injuries.
Six injury types with different healing patterns
can be distinguished:
Concussion
A slight injury to the periodontal ligament with edema and partial bleeding but without mobility of the affected tooth.
Subluxation
An injury with partial rupture of the periodon­tium structures accompanied by lip swelling and gingival sulcus bleeding.
Extrusion
An injury to the tooth characterized by a sub­total rupture of the periodontal ligament result­ing in partial displacement of the tooth out of its socket.
The affected tooth is elongated with high mobility to axial direction, accompanied by strong gingival sulcus bleeding and possible rup­ture of the papillae. The resulting hematoma pushes the tooth far out of the alveolus (Fig.23.5).