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R. Lati and A. Smiley
ization, improved dexterity, and tremor reduc­tion for surgeons. The robotic arms mimic the surgeon's movements while scaling them down, providing precise control during com­plex operations. Surgeons have embraced robotic assistance for procedures in every clinical surgical discipline from neurosurger­ies to like prostatectomies, hysterectomies, and colorectal surgeries, hepatobiliary sur­gery, and endocrine surgery, resulting in potentially decreased blood loss, shorter hos­pital stays, and improved patient outcomes.
3. Decision Support Systems (DSS): Technological advancements and the advent of electronic health records have paved the way for digital decision support systems in surgery. These systems leverage algorithms, data analytics, and articial intelligence to analyze patient-specic information and pro­vide evidence- based recommendations. DSS can assist surgeons in preoperative planning, predicting surgical outcomes, selecting treat­ment options, and assessing risks. By integrat­ing clinical data and evidence-based guidelines, DSS programs help surgeons make well- informed decisions tailored to individual patients.
4. Personalized Medicine: Genomic research and molecular proling have enabled person­alized surgical approaches. Genetic testing can identify specic genetic markers or muta­tions that inuence a patient's response to sur­gery, anesthesia, or drug therapies. This knowledge can guide surgical decision­making by identifying patients who might benet from particular procedures, predicting the likelihood of complications, optimizing drug selection, or identifying potential risks. Personalized medicine allows surgeons to customize treatment plans to individual patients, improving outcomes and reducing risks.
5. Enhanced Imaging Modalities: Advanced imaging technologies have had a profound impact on surgical decision-making. Magnetic resonance imaging (MRI), computed tomog­raphy (CT), and intraoperative ultrasound provide surgeons with detailed anatomical
information, facilitating precise surgical plan­ning and execution. These modalities help identify vital structures, vessels, and tumor margins, reducing the risk of complications and enabling more accurate and minimally invasive procedures. Additionally, intraopera­tive imaging systems provide real- time feed­back, enabling surgeons to adapt their strategies during surgery.
6. Risk Stratication Models: Predictive mod- els and risk stratication tools have emerged to estimate surgical risks and outcomes. These models use patient characteristics, clinical data, comorbidities, and sometimes genetic information to predict the probability of com­plications, length of hospital stay, or mortality rates. Surgeons can utilize this information to discuss risks and benets with patients, set realistic expectations, and adapt surgical plans or interventions accordingly. Risk stratica­tion models aid in shared decision-making, allowing patients to make informed choices about their surgical options.
7. Multidisciplinary Approach: Collaboration among multiple healthcare professionals has become integral to surgical decision-making. Surgeons now work closely with radiologists, pathologists, anesthesiologists, and other spe­cialists to ensure comprehensive patient eval­uation and optimize treatment plans. This multidisciplinary approach enables a holistic assessment of patients, incorporating exper­tise from various domains to develop the most appropriate surgical strategies. Collaborative discussions and input from different perspec­tives enhance surgical decision-making and contribute to improved patient outcomes.
These advancements collectively pave the way for more precise, individualized, and opti­mal surgical decision-making, improving patient outcomes and quality of care [14]. Ongoing research, innovations in articial intelligence, and further advancements in technology will likely continue to shape and rene surgical deci­sion-making approaches in the coming years.
But let’s get down to what really matters. Yet, in the center of all the above advances is the sur-
1 Surgical Decision-Making andtheChanging World
5
geon and what constitutes decision-making, since every surgical procedure potentially carries sig­nicant risks and complications. Despite the most conscientious preoperative preparations, surprising events may still occur. If the operation takes an unplanned turn, the surgeon has to make difcult decisions. Depending on the procedure, but an absolute must, continuous awareness of the patient’s physiologic status—including uid status, urine output, use of blood and blood prod­ucts, bleeding, current medications (such as vasopressors), and biochemical endpoints of resuscitation, frailty index, and how the patients look and feel, are the cornerstone of surgical decision-making. Even when the operation is going well, the biochemical prole of the patient may not be optimal, or even satisfactory, which may directly affect the outcome. In addition, the surgeon must recognize his or her own physio­logic status; if tired, for example, cutting corners and making major errors are much more likely. In my recent complex release of adhesion in a patient with complete mechanical bowel obstruc­tion from adhesions (grade 3 and 4), I noticed oozing from the raw surfaces. When I asked the anesthesia team, what was the patient’s tempera­ture, I was told 35.50C. He became cold and coagulopathic after three hours of intense lysis of adhesions. I decided to stop the procedure, pack his abdomen and performed a temporary abdomi­nal closure. Next day, after resuscitation and warming him up, I worked on him for three more hours and now he is recovering ne. The decision was a result of intense observation and communication.
Most recently, in order to assist in surgical decision-making and reduce errors and bias, among others, it has been suggested [3] the use of articial intelligence models that are continuously fed real-time data from electronic health records through mobile devices. By streamlining the data collection process and leveraging AI algorithms, the authors suggest that this approach may improve the accuracy and efciency of surgical decision-making. However, implementing this approach successfully would require overcoming certain obstacles. These include standardizing the data, ensuring the interpretability of AI models,
implementing and monitoring the system care­fully, addressing ethical concerns related to algo­rithm bias, being accountable for errors, and maintaining the importance of bedside assess­ments and human intuition in the decision- making process [1]. Irrespective of how helpful and crisp and fast, can AI be helpful, or potentially be help­ful, the missing link between AI and the patient will be trust and bond between the patient and sur­geon that needs to be established and maintained. This bond and trust can only be established with a handshake, looking straight in the eye of the patient, with detailed explanations or even regrets when we have, happiness when things go well, and sadness on the surgeon’s face, when things do not go as planned, or when there is not much that he/she can do. These are the most difcult conver­sations that we surgeons have with patients and their families. Articial intelligence cannot do that. It can summarize the literature quickly, so it will be useful, for some of us who are not up to date on every clinical issue.
In this book, as in the rst edition, we address these and other elements that are important for the perioperative decision-making process. For the majority of elective surgeries, the general checklist for surgery that includes some common steps and considerations include the preoperative evaluation, anesthesia consultation, preoperative instructions for the patient, surgical consent and discussion, preoperative preparation, preopera­tive medications and precautions, and time-out before the procedure starts, sufces, and it is designed to reduce surgical errors.
The question that has not been answered yet, is how do we as surgeons make intraoperative decisions? When a patient is dying in our hands from bleeding that we cannot control, when irre­versible metabolic shock does not respond to anything that we do, when new problems emerge out of the blue, when things go alarmingly wrong—in such dire moments during a carefully planned operation, how do we decide what to do next, and how should we overcome our own fears? Many of us make decisions that later on we cannot explain why we did things a certain way. Usually these are decisions made on the basis of a “gut feeling,” or “intuition,” or the “gray hair
6
R. Lati and A. Smiley
effect,” among other attributes. Yet, the anatomy of such decisions is of great importance to all sur­geons, patients, and those who work with sur­geons. In this book, we will review theoretical as well as any objective data that we as surgeons use to make perioperative decisions. The decisions we make, often with very limited information, will decide between someone living or dying. How do we make decisions in split seconds to take someone to the operating room now, as opposed to, let’s say “a bit later”? How do we decide to operate on a dying patient, without a CT scan, no laboratory data, just based on the fact that he or she is in shock, just to nd liters of blood in the abdomen, a torn vena cava, grade 4-5 liver injury, spleen, or some major blood vessel?
When the patient is dying in the operating room from massive bleeding, everyone panics, but the surgeon reaches in the open abdomen and compresses the aorta between his or her ngers, or puts a clamp on to let the anesthesia team catch up. Personally, when things get “tight,” I lower my voice and give deliberate commands. Is there a molecular explanation for this? Our collective rsthand experience as surgeons’ points to a combination of factors contributing to our intra­operative decision-making process, including education, clinical know-how, mentoring, and the creativity and excellence that come with long practice and with strict discipline.
Frankly, while the surgeon is the “captain of the ship,” there are many aspects of the surgical process that have recently received major public interest, which are not in the hands of surgeons at all. Involvement of other disciplines, mainly administration, regulations, insurance and gov­ernmental involvement, has taken many of these priorities, and even prevent surgeons from taking potential decisions. The majority of private and independent surgical groups, are no longer pri­vate, and no longer independent. They have been swallowed by the corporate world.
Prof Haile Debas, on his presidential address [1] titled “Surgery: A Noble Profession in a Changing World” given to American Surgical Association called surgery noble and quoted Webster’s Third New International Dictionary that denes the word
noble as:” (1) possessing outstanding qualities such as eminence, dignity; (2) having power of transmitting by inheritance; (3) indicating superior­ity or commanding excellence of mind, character, or high ideals or morals. Further, Prof Debas con­tinues: “These three attributes bet the profession
of surgery. Over centuries, the surgical profession has set the standards of ethical and humane prac­tice. Surgeons have made magnicent contribu­tions in education, clinical care, and science. Their landmark accomplishments in surgical science and innovations in operative technique have revolu­tionized surgical care, saved countless lives, and signicantly improved longevity and the quality of human life. Generations of surgeons have devel­oped their craft and passed it on to succeeding gen­erations, as they have to me and to each one of you, to take into the future.”
Practice of surgery has changed signicantly and dramatically; surgeons have become a replaceable workforce for major corporations, and worse we have become “shift doctors” man­aged by several VPs in expensive suits who often have just come out of MBA school, and have no clue how surgery or the department of surgery is run. Furthermore, As Prof Debas writes in the above cited paper: “Financial control and control
of access to healthcare were taken over by HMOs and insurance companies. As for-prot medicine proliferated, the health of our patients has come to be treated as a commodity traded daily on Wall Street. History will record that the medical pro­fession was sidelined and watched haplessly as MBAs and business executives dened the fate of healthcare. He calls these effects of HMO “deplorable”.”
While director and chairman of a major medi­cal center and academic department, I witnessed senior academic surgeons, deans, and others major academicians being “walked out” of the hospital or their ofces without any cause or explanation. They wanted to “move in a new direction.” The academic surgeons and surgery itself once the “crème de la crème” of the hospital, have come under major corporate attacks in the last 2-3 decades. Unfortunately, this is not hap­pening only in America. However, this hijacking
1 Surgical Decision-Making andtheChanging World
7
of the surgical world by the corporate world should not cloud our thoughts, our surgical deci­sions, and we should make the best decision pos­sible for every single patient that we evaluate and care for, by being trained well, being ready to care for every surgical disease. Surgeons should act like true leaders, own the care of the patient, lead the multidisciplinary and complex care with passion, love, and respect for everyone and those who directly affect people’s lives, save lives, and prevent morbidity.
The consequences may be because the sur­geon decided to operate, or when the surgeon makes a decision not to operate, or not to operate in a timely fashion. As my former Professor of surgery, Gazmend Shaqiri, a true (general, vascu­lar, cardiothoracic) surgeon used to tell us stu­dents at the University of Prishtina, Kosova, “When a patient dies in a medical ward, he or she dies from the disease; however, when the patient dies in the surgical ward, the patient dies from the surgery, or more importantly, of the decisions made by the surgeon.”
Every surgical decision that we make as sur­geons may have consequences, and regrets that have been reported in about 1in 7 surgical patients [2], both patient- and procedure-related. Yet, despite this gloomy outlook, surgery was and remains the best clinical discipline, and represents both a science and an art, and surgeons are the con­ductors of a symphony that truly needs to run per­fectly. There are other somewhat more silent consequences of surgical decision-makings. How articial intelligence will affect surgical decision making in the future it is not clear [3].
In a study of almost seven million patients, analyzed from the National Inpatient Sample database, we found that delaying the operation and not performing in the optimal time was the most common cause of mortality [4]. While we were unable to discern why the decision to oper­ate was delayed, the decision to operate or not is the surgeon’s and this decision not to operate had major consequences. While surgical procedures are far more complex than one individual’s deci­sions during surgery, there are elements to this small surgical microcosm that add additional
pressure on the surgeon and how he or she copes with this decision. Over the years, I have been reminded often of the consequences of making a decision, both wrong and right.
I am hoping this book will serve as a good ref­erence or even inspiration for others to explore the subject further and remind yourself what I teach everyone who listens that “surgery is easy, the decision is not. I did not and do not envision this as book of a bunch of algorithms both from some great books on the subject, or created by AI, whose computers are major polluter of our environment, to create strict protocols, although in a couple of chapters such suggestions have been made. I wanted this book to go a bit “beyond” the glory of being a surgeon and at the soul of the surgical decision-making process, and inside the surgeon being under his or her skin. I wanted to explore what makes the surgeon’s brain and heart “buzz,” and continue to work nonstop for many hours. While at Yale University, before the regulation of working hours for resi­dents, one of my vascular attending and I oper­ated basically non-stop from Friday morning until Sunday afternoon, with few “power naps” in the PACU or noisy operating room lounge between cases. When we nished Sunday after­noon, I thought I was doing “ne” until I went to start my car. Now that adrenaline was gone, I could not even drive myself home. I was com­pletely exhausted, and could not keep my eyes open. I had to call my wife Drita to come pick me up and take me home. How was I able to go on for so long while we were operating and yet, I could not drive myself home the ten miles to Hamden?
The anatomy and the physiology of the sur­geon are addressed in Chaps. 1 and 2. We cannot forget that we are not super creatures, despite what everyone may think of us; we are all just humans, like all others except we are leaders who really care.
Have you ever seen a surgeon emotionally “naked,” helpless, lonely, exhausted, disillu­sioned and, simply tired of everything? Even worse, most of us do not talk about the matter until it becomes a real problem. Not a pretty
8
R. Lati and A. Smiley
picture by all means. At this point, you may be thinking of friends and colleagues who commit­ted suicide or were on the brink of doing so. Drug and alcohol abuse, difculties with personal rela­tions, multiple divorces, or simply becoming obese and not caring for oneself are not uncom­mon among us surgeons. We are just humans, and yet like many other professions, we still have to get up and go to work, and make some incredible decisions, that will affect our patients and their families, and of course us, that we have to live with those decisions. Hopefully, this book will explain some of those decisions, and how we make them, but most importantly how we live with the decisions we make, and how we improve constantly.

References

1. Debas HT.Surgery: a noble profession in a changing
world. Annals of Surgery. 236(3):263–9.
2. Wilson A, Ronnekleiv-Kelly SM, Pawlik TM.Regret
in surgical decision making: a systematic review
of patient and physician perspectives. World J
Surg. 2017;41(6):1454–65. https://doi.org/10.1007/
s00268- 017- 3895- 9.
3. Loftus TJ, Tighe PJ, Filiberto AC, Efron PA,
Brakenridge SC, Mohr AM, Rashidi P, Upchurch
GR Jr, Bihorac A.Articial intelligence and surgical
decision-making. JAMA Surg. 2020;155(2):148–58.
https://doi.org/10.1001/jamasurg.2019.4917. PMID:
31825465; PMCID: PMC7286802.
4. Smiley A., Lati R.. The role of delayed operation
in hospital mortality in emergency general surgery
admissions: a 10-year study of 6,805,380 Patients.
Unpublished data.
Professor Rao Ivatury: ALegacy ofSurgical Decision-Making inTrauma Surgery, Excellence, Compassion, andHumility
RifatLati
2
Throughout his illustrious career, Dr. Rao R.Ivatury
revolutionized penetrating trauma with his groundbreaking advancements and unwavering commitment to patient care.
R. Lati (*) Department of Surgery, The University of Arizona, Tucson, AZ, USA
Tucson Medical Center, Department of Surgery, Tucson, AZ, USA e-mail: Lati@surgery.arizona.edu
© The Author(s), under exclusive license to Springer Nature Switzerland AG 2024 R. Lati (ed.), Surgical Decision-Making, https://doi.org/10.1007/978-3-031-67391-7_2
9
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R. Lati
His Textbook of Penetrating Trauma has been a bible of management of trauma surgery since it came out in 1996. (Photo of the book that I have on my desk and consult often to this day with his autograph and dedication to me.) In addition, the book Operative Techniques for Severe Liver Injury (2014) became a new model of manage­ment of liver trauma.
His expertise and dedication were unmatched, earning him immense respect and admiration from colleagues, patients, and the medical com­munity at large in all continents of the world. Dr. Ivatury’s legacy extends far beyond his profes­sional accomplishments; he was known for his
2 Professor Rao Ivatury: A Legacy of Surgical Decision-Making in Trauma Surgery, Excellence…
11
exceptional human character and humility, touch­ing the lives of all who had the privilege of know­ing him. His compassionate bedside manner, genuine empathy, and tireless advocacy for patient well-being set him apart as a truly remark­able individual. His surgical decision making was impeccable, always calm and collected, and always got ahead of death.
The loss of Dr. Ivatury is deeply felt by the trauma community worldwide, as his contribu­tions have had a lasting impact on the eld of emergency medicine. His innovative approaches to trauma care have saved countless lives and inspired future generations of medical profes­sionals. Dr. Ivatury’s absence leaves a void that will be difcult to ll, and his memory will con­tinue to be cherished by all of us who were fortu­nate enough to have crossed paths with this exceptional healer and visionary in the world of trauma medicine. He taught surgical decision making without making noise about it. He simply did it.
I met Dr. Ivatury or Iva as we fondly called him in June 1996 as a third-year General Surgery resident at Yale University Hospital, in New Haven, CT. That day, my Chairman, Dr. Ronald C Merrell, called me to his ofce to inform me that I needed to vacate my spot as the incoming fourth year resident to make room for another resident, Dr. Robert Knox, from the closing Bridgeport hospital residency program. Though unexpected, for me and for Dr. Merrell, he had arranged for me to join Professor Irvin Modlin’s laboratory at the VA Hospital, West Haven, CT few weeks later.
Coincidentally, on that Friday evening, one of the surgical critical care fellows informed me that Dr. Ivatury was giving a talk in New Haven and asked me to join him and go to that program. That evening, I met Dr. Ivatury, presented him with a copy of my book, Surgical Nutrition: Strategies in Critically Ill Patients, and told him that I am interested in a surgical critical care fellowship and sought his advice, since I have done 5 years of research before joining the residency. He invited me to an interview the following Monday and to meet some of other faculty. Following an interview with Dr. Ivatury and his partner Dr.
John Porter that Monday in June 1996, I was offered a fellowship in Surgical Critical Care at Lincoln Hospital in the Bronx, which due to Dr. Rao Ivatury was known as the Mecca of trauma surgery. And, thus, I entered the orbit of Rao Ivatury.
This meeting with Dr. Ivatury was one of the most important encounters, similar to the one when I met Dr. Stanley Dudrick (see chapter 23) in my life and career. I had been too busy operat­ing and was enjoying being a third-year resident and had not thought of a fellowship until then. However, after this fateful meeting with Dr. Merrell, I made the pivotal decision to pursue surgical critical care fellowship, and eventually become a trauma surgeon, a choice that would shape my future professional trajectory for years to come. This encounter with Dr. Ivatury was truly transformative and set me on a path that I am eternally grateful for. Daily trips by car or train (most of the time) to southern Bronx were memorable. I listen to books on tapes, or read books on trauma and critical care.
Finishing a fellowship in Surgical Critical Care was the best way to prepare for the next two nal chief years of my residency. Gaining com­petency in trauma and critical care is the most important way to really join the last few years of surgical residency. Walking (or running) in a trauma room without any hesitation or fear of what you will nd is an amazing and liberating feeling for a novice surgeon. Training in the Lincoln Bronx, the country’s most premier trauma center of those times, was a special treat and real destiny.
Following graduation from residency in July 1999, I joined both Dr. Ivatury and Dr. Merrell at Virginia Commonwealth University (VCU). Both had taken on new roles, with Dr. Merrell as the chairman of the department of surgery, and Dr. Ivatury as the chief of trauma. I became a close condant and partner of Dr. Ivatury during my time at VCU, forming a strong bond with him. Dr. Merrell, whom I had met during my time with Dr. Dudrick in Houston, Texas, at the Herman Hospital, the University of Texas, and who had become chairman of the department of Surgery at Yale University, invited me to leave
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R. Lati
Cleveland Clinic in Cleveland Ohio on December 6, 1993, where I was a categorical resident, and join Yale surgical residency program as a second year.
The transition from Yale to VCU marked a sig­nicant chapter in my career and solidied my relationship with Dr. Ivatury, further shaping my journey as a trauma and acute care surgeon. As the title of this essay, Dr. Rao Ivatury was an excellent and true master trauma and general sur­geon, outstanding author, editor, and researcher, all the while maintaining compassion and humil­ity, under whose quiet mentorship, I and many others who were lucky to work with him devel­oped and grew as a trauma surgeon.
While working together or being friends with Dr. Ivatury, after I moved to Arizona to work with John Porter, I recall another signicant moment that played a pivotal role in shaping further my destiny and professional journey. Dr. Merrell, a true pioneer in telemedicine, inuenced my inter­est in utilizing telemedicine and technology for rebuilding post-war countries. This newfound passion led me to delve into this eld further, when Dr. Merrell sent me to Toulouse in early 2000 for a telemedicine meeting. Subsequently, Dr. Merrell asked me to present him at the G8 Meeting in Berlin on May 4–5, 2000. My presen­tation titled The Anatomy of War and Destruction
of Kosovo: The Alumni’s View on Reconstruction of Health in Kosovo, showcased the vision for
leveraging telemedicine to aid in the reconstruc­tion and improvement of healthcare services in Kosova. This presentation marked a signicant milestone in my involvement with telemedicine and the advancement of healthcare initiatives in post-war regions like Kosova. It was in Berlin that I presented the idea to create the Telemedicine Project of Kosova and the International Virtual e-Hospital Network concept. Despite Dr. Merrell’s global leadership in telemedicine, there were no opportunities to establish trauma tele­medicine in Virginia at that time. I shared with Dr. Ivatury my plans to relocate to Tucson, Arizona, where Iva’s former partner John Porter was working, in January 2003. However, due to my commitment to oversee the building of the telemedicine center and program in Prishtina
starting in September 2002, I needed to leave, but still had to come back monthly to take calls at VCU and to meet my nancial obligations. Dr. Ivatury approved both decisions but expressed his hope that I would prioritize assisting my country, Kosova, before anything else.
Dr. Ivatury’s love and passion for helping underserved individuals in the Bronx and devel­oping countries around the world were truly immense. His unwavering commitment to sup­porting those in need, whether inlocal communi­ties or on a global scale, resonated deeply with all of us who knew him. His approval for me to travel the world, building telemedicine and trauma programs in various countries, was the best testament to his belief in the power of educa­tion, innovation, and compassion to make a posi­tive impact on healthcare systems and those they serve. Dr. Ivatury’s endorsement of my endeavors underscored his legacy of generosity, mentor­ship, and dedication to improving healthcare access for all. Our bond remained steadfast over the years, and Dr. Ivatury graciously accepted to become an Honorary Fellow of the Kosova College of Surgeons in 2021. Unfortunately, due to declining health, he was unable to travel to Kosovo and witness the progress we had made since the war. Our last conversation on the phone took place after the passing of his wife, Laila. I will deeply miss him, as will the world of trauma, which will feel the absence of his expertise and guidance, his compassion and humility. However, his written works will continue to educate and inspire generations to come. Dr. Ivatury’s legacy, wisdom, and compassion will forever be cher­ished and remembered through his writings and the lives he touched in profound ways.

Conclusion

Surgical decision-making is taught in a number of ways. Much of what I have done over the years and surgical decision that I made in trauma, I learned from Professor Rao Ivatury. He was mas­ter surgeon, a renowned trauma and critical care educator who has dedicated his career to improv­ing patient outcomes in emergency and trauma
2 Professor Rao Ivatury: A Legacy of Surgical Decision-Making in Trauma Surgery, Excellence…
13
care. Dr. Ivatury has made signicant contribu­tions to the eld through his research, teaching, and clinical practice, particularly in the areas of abdominal trauma, sepsis, and emergency medi­cal response. He has held leadership positions at multiple medical institutions and is considered a leading expert in the eld of trauma surgery. Dr. Ivatury’s work has had a lasting impact on the eld of emergency medicine and he continues to be a driving force in advancing the care of criti­cally ill and injured patients.
In addition to his professional achievements, Rao Ivatury, MD was known and will be remem­bered for his exceptional human character and
humble demeanor. He was and continues to be highly regarded by colleagues, patients, and stu­dents for his compassion, integrity, and dedica­tion to providing high-quality care. Despite his signicant accomplishments in the eld of trauma surgery, Dr. Ivatury remained approach­able and down-to-earth, always putting the needs of his patients rst. His humble nature and genu­ine concern for others have earned him the respect and admiration of those who have had the privilege of working with him. Dr. Ivatury’s com­bination of medical expertise and genuine kind­ness make him a truly exceptional physician and mentor.