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154
R. Peralta and R. Lati
a
b
cd
Fig. 13.7 (a–d). A 45 year old female with intra- abdominal catastrophe secondary to perforated sigmoid colon due to diverticulitis, underwent multiple trips to the operating room, post DCS, before she was eventually closed. (a) Patient who underwent DCS, eventually clo­sure primarily, followed by dehiscence and DCS. (b) Same patient as in Fig.13.7a, now with frozen abdomen.
(c) Due to frozen abdomen, and inability to perform pos­terior component release, we decided to “parashoot” the biologic mesh for re-enforcement. (d) Final placement of StratticeTM (biologic mesh), that was followed by “en­mass” closure. (Fig.13.8e). (** All gures are courtesy of Rifat Lati, MD)
13 Surgical Decision-Making Process andDenitive Abdominal Wall Reconstruction: AnUpdate
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e
Fig. 13.8 En masse closure of abdominal wall tissue in patient Fig.13.7. (e) En masse closure of abdominal wall tissue. (** All gures are courtesy of Rifat Lati, MD)

Summary

The reconstruction of complex abdominal wall defects continues to evolve and still poses a major challenge for the clinical surgeon. Successful abdominal wall reconstruction relies primarily on good judgment, careful perioperative prepara­tion, expertise in performing the surgical tech­nique, and close follow-up. The physiology of the patient, defect size, its location, and level of contamination are considerations that inuence the type of repair of abdominal wall defects and kind of mesh used [54].

References

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24. Deerenberg EB, Elhage SA, Shao JM, Lopez R, Raible RJ, Kercher KW, Colavita PD, Augenstein VA, Heniford BT.The effects of preoperative botulinum toxin a injection on abdominal wall reconstruction. J Surg Res. 2021;260:251–8. https://doi.org/10.1016/j.
jss.2020.10.028. Epub 2020 Dec 23.
25. Tashkandi A, Bueno-Lledó J, Durtette-Guzylack J, Cayeux A, Bukhari R, Rhaeim R, etal. Adjunct botox to preoperative progressive pneumoperitoneum for incisional hernia with loss of domain: no additional effect but may improve outcomes. Hernia. 2021.
https://doi.org/10.1007/s10029- 021- 02387- 8.
26. de Vries Reilingh TS, etal. Repair of giant midline abdominal wall hernias: “components separation technique” versus prosthetic repair. World J Surg. 2007;31(4):756–63.
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28. Leppäniemi A. The hostile abdomen—a system­atic approach to a complex problem. Scand J Surg. 2008;97(3):218–9.
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31. Kushimoto S, et al. Usefulness of the bilateral anterior rectus abdominis sheath turnover ap method for early fascial closure in patients requir­ing open abdominal management. World J Surg. 2007;31(1):2–8.
32. Sailes FC, et al. Synthetic and biological mesh in component separation: a 10-year single institution review. Ann Plast Surg. 2010;64(5):696–8.
33. Espinosa-de-los-Monteros A, et al. Components­separation technique for closure of transverse non­midline abdominal wall incisional hernia. J Plast Reconstr Aesthet Surg. 2011;64(2):264–7.
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org/10.1016/j.jamcollsurg.2012.02.017. Epub 2012
Apr 21. PMID: 22521439; PMCID: PMC3889113.
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40. Servant JM, etal. Reconstruction of large thoracoab­dominal defects using two-stage free tissue transfers and prosthetic materials. J Plast Reconstr Aesthet Surg. 2006;59(4):360–5.
41. Erni D, Harder Y. The dissection of the rectus abdominis myocutaneous ap with complete preser-
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53. Cobb WS, etal. Open retromuscular mesh repair of complex incisional hernia: predictors of wound events and recurrence. J Am Coll Surg. 2015;220(4):606–13.
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jamasurg.2021.6902.
Surgical Decision-Making inDicult Situations inPediatric Surgery
B.S.Ratta, GeetaKekre, DhananjayVaze, andKshamaKulkarni
14

Introduction

Pediatric surgery encompasses a wide array of clinical scenarios, each presenting unique chal­lenges and complexities. Within this specialized eld, surgical decision-making in difcult situa­tions demands a nuanced and comprehensive approach. To illustrate the intricacies of surgical decision-making in pediatric cases, we will explore the diverse use cases spanning congenital anomalies, trauma, oncology, and other complex conditions. These use cases showcase the multi­faceted nature of surgical decision-making in pediatric surgery, emphasizing the need for meticulous evaluation, collaboration, and ethical considerations in managing challenging scenarios.
Decision-making is a complex process, and surgical decision-making is no exception to the rule. It is not only complex to start with but needs renement, adjustments, and reconsidera­tion till the desired results are achieved. It is a process that happens at subconscious and con-
B. S. Ratta (*) · G. Kekre Department of Pediatric Surgery, Ruby Hall Clinic, Pune, India
D. Vaze Department of Pediatric Surgery, DY Patil Medical College, Pune, India
K. Kulkarni Department of Pediatric Surgery, Surya Hospital, Pune, India
scious/intellectual levels. These two levels can’t be visualized as water-tight compartments but need to be perceived as a continuum. An expert surgeon condently and repeatedly works through these levels to review, reanalyze, and reassess their own decisions to achieve the desired result.
Pediatric surgeons are tasked with making decisions that not only address immediate con­cerns but also consider the evolving needs of children as they grow. Congenital anomalies, growth-related changes, and the need for mini­mally invasive yet effective interventions are just a few of the challenges that make pediatric sur­gery distinct.
In the pediatric population, “surrogate decision- makers” are often required for the con­senting process to help understand the underlying pathology. This is especially important in some life-threatening emergencies like inhaled foreign bodies and midgut volvulus. In developing coun­tries, it is a social emergency to assign sex for the upbringing of a child born with ambiguous genitalia.
The challenges one faces when operating on a child may be medical as well as socioeconomic. In pediatric practice, one is likely to encounter children with associated genetic syndromes or multiple congenital anomalies. Resources for such patients are often limited. Equipment of the appropriate dimensions and expertise in ancillary services may not readily be available. Nevertheless, judicious utilization of available
© The Author(s), under exclusive license to Springer Nature Switzerland AG 2024 R. Lati (ed.), Surgical Decision-Making, https://doi.org/10.1007/978-3-031-67391-7_14
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resources could make the difference between morbidity (or even mortality) and a healthy life with normal life expectancy for these children.

The Medically Complex Pediatric Surgical Patient

It is not uncommon to be faced with a surgical problem in a pediatric patient who suffers from a genetic, chromosomal, or metabolic syndrome. Ideally, such patients should be cared for at spe­cialized centers with dedicated multidisciplinary pediatric teams. However, it is not rare for such children to present in an emergency at the health­care facility nearest to them.
Assessing a syndromic child in an emergency requires a calm and patient approach. A detailed history from the parent or caregiver when avail­able will provide valuable information that can help a surgeon understand the signs exhibited by the child. For example, a child with a neurologi­cal condition presents with what might be appen­dicitis but may not cry out loud even when in agony. A caregiver will be able to point out gri­maces and facial expressions of pain. Children with special needs may be difcult to soothe and cajole, making it challenging to pick up signs such as guarding and rebound tenderness.
Anesthesia risks require due consideration when treating such children. It is always advis­able to have pediatric intensive care available at the same center where the surgery is being per­formed. Difcult airway, poor muscle tone, and altered metabolism greatly increase the risks of general anesthesia. Post-operative care, wound care, analgesia, and drug therapy all must be tai­lored keeping in mind the child’s physical and mental status.
Pediatric Surgical Emergencies intheResource-Limited Setting
A time-sensitive emergency in a pediatric patient needs to be handled with prudence. Utilization of resources, especially diagnostic, must be opti­mized to provide the best patient outcomes.
Resources such as time, imaging modalities, ancillary services, nances, intensive care, etc. may all be in short supply. The astute surgeon must decide on the need for surgery, plan for the surgical process, and execute the surgery while keeping the patients’ interests in mind.

Testicular Torsion

A common example of a time-sensitive pediatric emergency is testicular torsion. One may not have a sonologist on hand to demonstrate the lack of testicular blood ow, but a sound clinical eval­uation and a high index of suspicion should enable the surgeon to establish the diagnosis. A reasonable surgeon may decide to explore the scrotum rather than wait for imaging when the index of suspicion is high.

Midgut Volvulus

Another example of a surgical emergency that may not allow the luxury of detailed imaging is midgut volvulus in the newborn. One may have little more than an X-ray and a clinical picture of bilious vomiting in the infant, with sonographic assessment either unavailable or not possible at the given moment. It may be better in that sce­nario to operate right away than to wait and run the risk of compromised bowel vascularity.

Trauma

The most limited resource while dealing with pediatric trauma is time. Surgical decisions in pediatric trauma must be guided above all by the patient’s clinical picture. There is no benet to rushing a hypovolemic, hypothermic child into a CT scanner before adequate uid resuscitation is done. Point-of-care ultrasound to detect free uid in the abdomen and the thorax when available can guide management. A detailed ultrasound study is seldom required. Lack of response to uid resuscitation in a child with abdominal or thoracic trauma should prompt surgical explora-
14 Surgical Decision-Making inDicult Situations inPediatric Surgery
161
tion rather than further imaging. A thorough clin­ical assessment, including a log roll and a per rectal examination, and a clear picture of the mechanism of injury (when available) go a long way in guiding surgical management. Bear in mind that blood pressure is an unreliable indica­tor of volume status in the pediatric patient. A decision on nonoperative management of solid organ injury will depend on the availability of intensive monitoring and a well-staffed 24-hour operating suite. In the absence of these, one must choose between transferring the patient to a cen­ter with these facilities or exploring the abdomen upfront.

Ileocolic Intussusception

The management of ileocolic intussusception is evolving toward nonoperative reduction. However, there are multiple caveats to this state­ment. Nonoperative reduction is best suited to ileocolic intussusception in a child between 6months and 18months of age. Outside this age group, nonoperative reduction must be approached with caution. The likelihood of a pathological lead point including a malignancy such as lymphoma being the cause of intussus­ception is high outside this age group. Even in the absence of a pathological lead point, nonopera­tive reduction is less likely to be successful in an intussusception older than 48hours or in a dis­tended abdomen. Obvious intestinal obstruction is a contraindication for nonoperative reduction. When attempting nonoperative reduction, the operating room must be ready for an emergency exploration. Intestinal perforation is a common and dreaded complication of nonoperative reduc­tion necessitating immediate exploration.
Factors Contributing toSurgical Decision-Making inDicult Situations
1. Clinical complexity in pediatric surgical
patients often presents with complex clinical conditions such as congenital anomalies,
tumors, or traumatic injuries. These complex cases require thorough evaluation and careful consideration of treatment options.
2. Anatomical variations in children’s anatomy can differ signicantly from that of adults posing challenges for surgical planning and execution. Anatomical variations in pediatric patients can impact the choice of surgical approach and techniques.
3. Physiological considerations such as the impact of surgery on growth and develop­ment, as well as the unique metabolic and nutritional needs of pediatric patients, must be factored into surgical decision-making.
4. Ethical and legal considerations in surgically treated pediatric patients often involve com­plex ethical and legal considerations such as the need for parental consent, the best inter­ests of the child, and the potential long-term implications of surgical interventions.
Strategies forSurgical Decision­Making inDicult Situations
1. Multidisciplinary approach: in difcult surgi­cal cases involving a multidisciplinary team of pediatric surgeons, pediatric anesthesiolo­gists, intensivists, and other specialists can provide comprehensive insights and expertise. Collaboration among team members can help in formulating the most appropriate treatment plan.
2. Shared decision-making: engaging parents or guardians in shared decision-making pro­cesses is essential in pediatric surgical care providing families with comprehensive information regarding the surgical options, potential risks, and expected outcomes allows families for more informed decision-making.
3. Advanced imaging and technology: utilizing advanced imaging modalities such as MRI, CT, and 3D modeling can aid in preoperative planning and intraoperative decision-making. These technologies provide detailed anatomi­cal information allowing for precise surgical interventions.
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4. Ethical consultation: in complex cases with ethical dilemmas, involving an ethics commit­tee or consultant can offer valuable insights and guidance in navigating the ethical considerations surrounding surgical decision-making.
5. Simulation and rehearsal: in some complex pediatric surgical cases, especially those involving rare anatomical anomalies or chal­lenging procedures, simulation and rehearsal of the surgical approach can be invaluable. This can help anticipate potential complica­tions and rene the surgical plan.

Use Cases

Use Case 1: Neonatal Abdominal Catastrophes

Surgical decision-making in neonatal abdominal catastrophes involves complex considerations due to the delicate nature of neonatal patients and the potential severity of abdominal conditions. Neonatal abdominal catastrophes may include conditions such as intestinal obstruction, necro­tizing enterocolitis, gastroschisis, omphalocele, and other congenital anomalies.
A surgeon called to the neonatal intensive care unit (NICU) to evaluate and plan treatment for a newborn baby with a surgical emergency must make some crucial decisions. When is the best time to operate the baby? What is the best surgery to perform in the given circumstances? Must this be a staged surgery? It is important to keep in mind that neonates have limited to no reserve, are highly susceptible to sepsis, and present a formi­dable anesthesiology challenge.
Anorectal Malformations
Anorectal malformations (ARMs) require imme­diate attention in the newborn period. If neglected, a neonate with an ARM will develop overt fea­tures of intestinal obstruction which can be life­threatening. Feeding must be held off until the malformation has been assessed and a decision on surgery has been made. Examination and
investigation for associated cardiac, spinal, and renal defects and VACTERL-H association must be complete. A prone cross-table X-ray lm helps to identify the level of the malformation.
Broadly speaking, all malformations other than vestibular stula in girls and some types of perineal stula in boys require a staged approach. The rst step is to construct a suitable colostomy to provide an outlet for stool. This colostomy must be constructed keeping in mind the subse­quent surgery. An adequate length of colon distal to the ostomy must be preserved to allow pull­through at a later date. Accordingly, the surgeon must construct a high sigmoid divided colostomy. In some cases, particularly in high lesions and in the pouch colon, it may be more prudent to con­struct a right transverse colostomy. However, children do not tolerate proximal bowel diver­sions as well as adults do. They are especially susceptible to dehydration, malnutrition, anemia, and prolapse with ileostomies and poorly con­structed transverse colostomies.
A perineal or a vestibular stula may be ade­quate to allow decompression of the bowel of a breastfed infant. In such cases, surgery can be deferred until the child can undergo a primary reconstruction. Where facilities are available, pri­mary reconstruction can be done in the rst 72 hours of life while the baby is still in the NICU.However, at most centers, it is still stan­dard practice to perform the reconstruction once the child has demonstrated satisfactory weight gain. Home rectal washouts are administered in the interim to ensure that the bowel remains decompressed.
Esophageal Atresia withor Without Tracheo-esophageal Fistula
A potentially life-threatening anomaly, esopha­geal atresia, calls for vigilance and promptness in surgical decision-making. The clear priorities are to prevent aspiration and to establish a conduit for feeding. Rapid evaluation for associated car­diac anomalies and the VACTERL-H association is imperative before intervention. The presence of a right-sided aortic arch as detected by 2D echo has a bearing on the operative approach.
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Surgery is usually deferred until the rst 24hours of life have passed. An X-ray taken after this interval is a more reliable indicator of whether or not a tracheo-esophageal stula is present. Until surgery is possible, the lungs must be protected from aspiration pneumonitis by thorough oral suctioning and use of a Replogle tube. Reux of secretions from the stomach into the lungs via the tracheo-esophageal stula must be prevented by appropriate positioning. If the child has to be transferred to another center for surgery, suctioning must continue during transport.
If an X-ray taken after 16 to 24hours of birth shows no abdominal gas shadows, it is unlikely that a stula between the esophagus and the tra­chea exists. In that case, one may forego thoracic exploration in the newborn period and simply construct a cervical esophagostomy and a feed­ing gastrostomy, with the understanding that the child will require gastroesophageal replacement at a later date.
If a stula is found to be present, it must be ligated through a thoracic approach. One must be careful to identify the stula correctly because it is easy to mistake the left bronchus or the aorta for the stula in such a tiny thoracic cavity. Moreover, either or both of the proximal and dis­tal esophageal pouches may be communicating with the trachea in which case both connections need to be ligated. The surgical approach is usu­ally through the right hemithorax, hence the sig­nicance of identifying a right-sided aortic arch by looking for it on 2D echo.
Once the stula has been ligated, a careful attempt must be made to establish esophageal continuity by a primary anastomosis. Care must be taken to avoid overzealous dissection and mobilization which can jeopardize the vascular­ity of the esophageal segments. A wide, oblong anastomosis is performed to minimize anasto­motic stricture. Anti-reux medication must be administered postoperatively. The child must be monitored for any signs of anastomotic disruption.
If a primary anastomosis is not possible, or a major anastomotic leak has developed, then a
cervical esophagostomy with a feeding gastros­tomy must be performed. If an anastomosis looks tenuous at the time of surgery, it is advisable to convert to a cervical esophagostomy with a feed­ing gastrostomy, as an anastomotic leak into the mediastinum can cause a newborn to deteriorate rapidly.
Myelomeningocele
Open neural tube defects are a direct portal for infection to the central nervous system (CNS). Moreover, they carry the risk of traumatic rupture and fatal coning in that event. It is for this reason that the defect must be closed within the rst few days of birth. A ventriculoperitoneal shunt is more often than not inserted during the same sur­gery. Emphasis is placed on maintaining asepsis and protecting the defect with sterile nonadhesive and nonirritant dressings until surgery can be per­formed. Cultures are obtained from the exposed neural placode to document sterility or contami­nation. The motor and sensory decit must be well documented before closure. Although clo­sure is not expected to improve neurological de­cits, care must be taken not to worsen it. Parental counseling regarding bowel and bladder manage­ment must begin at the time of diagnosis.
Intestinal Atresia
Intestinal atresia poses a surgical challenge due to the wide discrepancy between the proximal and distal bowel. The intestine proximal to the site of atresia may be many times the diameter of the distal unused intestine making end-to-end anastomosis difcult. Moreover, the ectatic prox­imal intestine is often hypoperistaltic, leading to stasis and increasing the risk of recurrent obstruc­tion or anastomotic leak. The ectasia may extend over a great length of the proximal intestine; therefore resection of the dilated bowel is not always a practical solution. Tapering or plication of the proximal bowel may be done with the attendant risk of a leak from the extended suture line or obstruction from the plicated bowel. Multiple atresias are often encountered, and mul­tiple anastomoses may be performed in these cases. The goal is to preserve as much bowel as
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possible, prevent short bowel syndrome, and minimize the need for parenteral nutrition. Of course, this may be easier said than done. Multiple intestinal atresias and apple peel defects of the mesentery often leave the surgeon with little choice. It is necessary in those cases to work closely with the neonatologist to establish paren­teral nutrition as well as enteral feeding.
Gastroschisis andRuptured Omphalocele
An abdominal catastrophe such as a ruptured omphalocele or a gastroschisis can be alarming at rst, but a calm and measured approach is neces­sary in both situations. The rst priority of the treating team is to prevent sepsis, hypothermia, and dehydration. Where feasible, immediate reduction can be achieved in the obstetric operat­ing room provided the center is equipped for intensive monitoring of abdominal compartment syndrome. Where immediate or primary closure is not possible or carries a high risk of abdominal compartment syndrome, a sterile silastic silo bag must be applied. In case the child must be trans­ported to another facility, care must be taken not to injure or aggravate the inammation of the bowel. The infant may be wrapped in a sterile plastic sheet to prevent loss of uid and heat as well as to prevent contamination of the exposed bowel. Delayed closure can then be undertaken at a well-equipped facility. During closure, the sur­geon needs to keep an eye on lower limb perfu­sion and ventilatory pressures. Decreased lower limb perfusion which can be identied by the use of a saturation probe on the foot and increased ventilatory pressure requirements to deliver tidal volume indicate raised intra-abdominal pressure. The surgeon may in this case opt to create a ven­tral hernia by closing the skin and without clos­ing the fascia. Alternatively, lateral release incisions may be placed on the skin and fascia. Gastroschisis is often associated with intestinal atresia. However, exposure to amniotic uid in utero renders the bowel edematous and inamed, unsuitable for resection and anastomosis. Therefore, it may be necessary to re-operate on the patient for an atresia a few days after closure.
The child will require parenteral nutrition in the interim.
Complicated Appendicitis (Abscess or Phlegmon Formation)
A lack of physiologic and immunologic reserve, a small abdominal cavity allowing an intra­abdominal infection to easily spread, a relatively small omentum that cannot wall off an infection, and a thin-walled appendix in young age group increase the morbidity and mortality for appendi­citis. Neonatal and infant perforation rates are high; hence tailoring of surgical recommenda­tions is needed. This is because many times the leucocyte counts may remain normal and the appendix may not be visualized or only mildly enlarged on ultrasonography in this age group.
Patients with imaging consistent with perfo­rated appendicitis with an associated large phleg­mon or abscess may be managed nonoperatively with intravenous (IV) antibiotics, with percutane­ous drainage of abscesses if technically feasible. Alternatively, appendectomy may be appropriate management in the hands of a skilled provider if available. For patients managed nonoperatively for their appendiceal abscess, the routine practice is to do an interval laparoscopic appendectomy; however, there are data to support that patients do not require standard “interval appendectomy” 6weeks following resolution; these cases should be individualized based on the shared decision between the parents of the child and the surgeon.
Complicated Inguinal Hernias
Any infant who has an inguinal hernia risks hav­ing their bowels becoming incarcerated and, in severe cases, strangulated. Most inguinal hernias are asymptomatic, and corrective surgery is advised early to avoid complications. Manual reduction of the incarcerated hernia is tried ini­tially, and if successful, the child is posted for denitive repair in the next 24 to 48hours. If the incarcerated inguinal hernia is left unreduced, these infants progress rapidly to strangulation. However, in children with an incarcerated ingui­nal hernia, reduction should be performed only if