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points to a combination of factors contributing to our intraoperative decision­making process. These factors include education, clinical know-how, mentor­ing, and the creativity and excellence that come with long practice and with strict discipline.
The aim of this book is to evaluate the current literature on the subject and to explore what is known and, more importantly, what is not known about this process. Frankly, while the surgeon may be considered the “captain of the ship,” there are many aspects of the surgical process that have recently received major public interest, and these aspects are not in the hands of sur­geons at all. Involvement of these other disciplines—mainly administration, regulations, insurance, and government—has become a priority in many cases. Often, we forget that surgery is both a science and an art, and surgeons are the conductors of a symphony that truly needs to run perfectly. There are other differences between surgeons and the physicians in many other clinical disciplines. While I was a medical student at the University of Prishtina, Kosova, Professor of Surgery, Dr. Gazmend Shaqiri would tell me and others: “When a patient dies in a medical ward, he or she dies from the disease; how­ever, when the patient dies in surgical ward, the patient dies from the surgery, or more importantly, from the decisions made by the surgeon.” This may be a decision by the surgeon to operate or not to operate. While surgical proce­dures are far more complex than one individual’s decisions during surgery, there are elements to this small surgical microcosm that add additional pres­sure on the surgeon and how he or she copes with this decision. Over the years, I have been reminded often of the consequences of making a decision, both wrong and right.
When I started this book, I thought it would be a single-author book, somewhat of a real rarity these days. However, as the months were passing by and the project was not being completed, I saw the real reason why: I really wanted to have other opinions on the matter.
I am hoping this book will serve as a good reference or even inspiration for others to explore the subject further. I did not and do not envision this as a book of algorithms and strict protocols although in a few chapters such sug­gestions have been made. I wanted myself and the other chapter authors to go a bit “beyond” the surgical decision-making process and inside the surgeon as being. I wanted to see if we can explore what makes the surgeon’s brain and heart “buzz” and continue to work nonstop for many hours.
While at Yale University, before the regulation of working hours for resi­dents, one of my vascular attendings and I operated basically nonstop from Friday morning until Sunday afternoon, with a few “power naps” between cases. I thought I was doing “ne” until I went to start my car. Now that the adrenaline was gone, I could not even drive myself home. I was completely exhausted and could not keep my eyes open. I had to call my wife Drita to come pick me up and take me home. How was I able to go on for so long while we were operating and yet I could not drive myself the 10miles home? The anatomy and the physiology of the surgeon are addressed in Chaps. 1 and
2. We cannot forget that we are not super creatures, despite what everyone
may think of us; we are all just human.
Prologue to First Edition
Prologue to First Edition
xiii
Have you ever seen a surgeon emotionally “naked,” burnt out, exhausted, disillusioned, and simply tired of everything? Even worse, most of us do not talk about the matter until it becomes a real problem. Not a pretty picture by any means. At this point, you may be thinking of friends and colleagues who committed suicide or were on the brink of doing so. Drug and alcohol abuse, difculties with personal relationships, multiple divorces, or simply becom­ing obese and not caring for oneself are not uncommon among surgeons. We are just human, and yet, like many other professions, we still have to get up and go to work and make some incredible decisions that will affect our patients and their families and, of course, us, and we have to live with those decisions.
I hope this book will explain some of those decisions and how we make them, but, most importantly, how we live with the decisions we make and how we improve constantly.
Valhalla, NY, USA RifatLati Spring 2016

Prologue to Second Edition

Since the publications of the rst edition of this book, there have been signi­cant advancements in surgical decision-making that surgeons have embraced and developed. Here are some noteworthy developments:
1. Minimally Invasive Surgery (MIS): Over the past decade, MIS tech-
niques have expanded to numerous surgical specialties, including general surgery, urology, gynecology, and orthopedics. These procedures involve smaller incisions, specialized instruments, and often the use of laparo­scopes or endoscopes for visualization. Benets include reduced damage to surrounding tissues, less postoperative pain, shorter hospital stays, and faster recovery times for patients. Surgeons now have a broader range of minimally invasive options to consider when planning surgeries.
2. Robotic-Assisted Surgery: Robotic surgical systems, such as the da
Vinci Surgical System, have made signicant strides in the last decade. These systems offer enhanced visualization, improved dexterity, and tremor reduction for surgeons. The robotic arms mimic the surgeon’s movements while scaling them down, providing precise control during complex operations. Surgeons have embraced robotic assistance for pro­cedures like prostatectomies, hysterectomies, and colorectal surgeries, resulting in potentially decreased blood loss, shorter hospital stays, and improved patient outcomes.
3. Decision Support Systems (DSS): Technological advancements and the
advent of electronic health records have paved the way for digital DSS in surgery. These systems leverage algorithms, data analytics, and articial intelligence to analyze patient-specic information and provide evidence­based recommendations. DSS can assist surgeons in preoperative plan­ning, predicting surgical outcomes, selecting treatment options, and assessing risks. By integrating clinical data and evidence-based guide­lines, DSS programs help surgeons make well-informed decisions tailored to individual patients.
4. Personalized Medicine: Genomic research and molecular proling have
enabled personalized surgical approaches. Genetic testing can identify specic genetic markers or mutations that inuence a patient’s response to surgery, anesthesia, or drug therapies. This knowledge can guide surgical decision-making by identifying patients who might benet from particu­lar procedures, predicting the likelihood of complications, optimizing drug selection, or identifying potential risks. Personalized medicine
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allows surgeons to customize treatment plans to individual patients, improving outcomes and reducing risks.
5. Enhanced Imaging Modalities: Advanced imaging technologies have
had a profound impact on surgical decision-making. Magnetic resonance imaging (MRI), computed tomography (CT), and intraoperative ultra­sound provide surgeons with detailed anatomical information, facilitating precise surgical planning and execution. These modalities help identify vital structures, vessels, and tumor margins, reducing the risk of compli­cations and enabling more accurate and minimally invasive procedures. Additionally, intraoperative imaging systems provide real-time feedback, enabling surgeons to adapt their strategies during surgery.
6. Risk Stratication Models: Predictive models and risk stratication
tools have emerged to estimate surgical risks and outcomes. These models use patient characteristics, clinical data, comorbidities, and sometimes genetic information to predict the probability of complications, length of hospital stay, or mortality rates. Surgeons can utilize this information to discuss risks and benets with patients, set realistic expectations, and adapt surgical plans or interventions accordingly. Risk stratication mod­els aid in shared decision-making, allowing patients to make informed choices about their surgical options.
7. Multidisciplinary Approach: Collaboration among multiple healthcare
professionals has become integral to surgical decision-making. Surgeons now work closely with radiologists, pathologists, anesthesiologists, and other specialists to ensure comprehensive patient evaluation and optimize treatment plans. This multidisciplinary approach enables a holistic assess­ment of patients, incorporating expertise from various domains to develop the most appropriate surgical strategies. Collaborative discussions and input from different perspectives enhance surgical decision-making and contribute to improved patient outcomes.
Prologue to Second Edition
These advancements collectively pave the way for more precise, individu­alized, and optimal surgical decision-making, improving patient outcomes and quality of care. Ongoing research, innovations in articial intelligence, and further advancements in technology will likely continue to shape and rene surgical decision-making approaches in the coming years.
But let’s get down to what really matters. While the new technological advances are very important, in the center of all the above advances is the surgeon and what constitute the decision-making. Despite the most conscien­tious preoperative preparations, surprising events may still occur. If the oper­ation takes an unplanned turn, the surgeon has to make difcult decisions. Depending on the procedure, continuous knowledge and awareness of the patient’s physiologic status—including uid status, urine output, use of blood and blood products, bleeding, current medications (such as vasopressors), and biochemical endpoints of resuscitation, frailty index and how the patients look and feel, are cornerstone of surgical decision-making. Even when the operation is going well, the biochemical prole of the patient may not be optimal, or even satisfactory, which may directly affect the outcome. In addi-
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tion, the surgeon must recognize his or her own physiologic status; if tired, for example, cutting corners and making major errors are much more likely. In my recent complex release of adhesion in patient with complete mechani­cal bowel obstruction from adhesions (grade 3 and 4), I noticed oozing from the raw surfaces. When I asked the anesthesia team, what was the patient’s temperature, I was told 35.5°C.He became cold and coagulopathic after 3h of intense lysis of adhesions. I decided to stop the procedure, pack his abdo­men, and performed a temporary abdominal closure. The next day, after resuscitation and warming him up, I worked on him for three more hours and he recovered ne. The decision was a result of observation and communica­tion. In order to assist in surgical decision-making, and reduce errors and bias, among others, we suggest the use of articial intelligence (AI) models that are continuously fed real-time data from electronic health records through mobile devices. By streamlining the data collection process and leveraging AI algorithms, the authors suggest that this approach may improve the accu­racy and efciency of surgical decision-making. However, implementing this approach successfully would require overcoming certain obstacles. These include standardizing the data, ensuring the interpretability of AI models, implementing and monitoring the system carefully, addressing ethical con­cerns related to algorithm bias, being accountable for errors, and maintaining the importance of bedside assessments and human intuition in the decision­making process (Debas 2002). Irrespective of how helpful, and fast AI can potentially be, the missing link between AI and the patient will be trust and bond between the patient and the surgeon that needs to be established and maintained. This bond and trust between the patient and the surgeon is most important element and can only be established with a “hand shake”, a straight look in the eye of the patient, detailed explanations, even the regrets when we have, happiness when things go well, and sadness seen on the surgeon’s face when things do not go as planned, or when there is not much that he or she can do. These are the most difcult conversations that we surgeons have with patients and their families. AI cannot do that. It can summarize the literature quickly, so it will be useful for some of us who are not up to date on every clinical issue.
In this book, as in the rst edition, we address these and other elements that are important for the perioperative decision-making process. For the majority of elective surgeries, the general checklist for surgery that includes some common steps and considerations include the preoperative evaluation, anesthesia consultation, preoperative instructions for the patient, surgical consent and discussion, preoperative preparation, preoperative medications and precautions, and time-out before the procedure starts, sufces, and it is designed to reduce surgical errors.
But, the question that has not been answered yet is, how do we as surgeons make intraoperative decisions? When a patient is dying in our hands from bleeding that we cannot control, when irreversible metabolic shock does not respond to anything that we do, when new problems emerge out of the blue, when things go alarmingly wrong—in such dire moments during a carefully planned operation, how do we decide what to do next, and how should we
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Prologue to Second Edition
overcome our own fears? Many of us make decisions that later on we cannot explain why we did things a certain way. Usually these are decisions made on the basis of a “gut feeling,” or “intuition,” or the “gray hair effect,” among other attributes. Yet, the anatomy of such decisions is of great importance to all surgeons, patients, and those who work with surgeons. In this book, we will review theoretical as well as any objective data that we as surgeons use to make perioperative decisions. The decision we make, often with very lim­ited amount of information, will decide between someone living or dying. How do we make decisions in split seconds to take someone to the operating room now, as opposed to, let’s say “a bit later”? How do we decide to operate on a dying patient, without a CT scan, no laboratory data, just based on the fact that he or she is in shock, just to nd liters of blood in the abdomen, a torn vena cava, grade 4–5 liver injury, spleen, or some major blood vessel?
When the patient is dying in the operating room from massive bleeding, everyone panics, but the surgeon reaches in the open abdomen and com­presses the aorta between his or her ngers, or puts a clamp on to let the anesthesia team catch up. Personally, when things get “tight,” I lower my voice and give deliberate commands. Is there a molecular explanation for this? Our collective rsthand experience as surgeons’ points to a combination of factors contributing to our intraoperative decision-making process, includ­ing education, clinical know-how, mentoring, and the creativity and excel­lence that come with long practice and with strict discipline.
Frankly, while the surgeon is the “captain of the ship,” there are many aspects of the surgical process that have recently received major public inter­est, which are not in the hands of surgeons at all. Involvement of administra­tion, regulations by varies agencies, insurance, and governmental involvement, may affect how surgeons make potential decisions. Recently, my decision to use a certain medical product was questioned by administration. Direct inter­ference in my surgical decision making. The majority of private and indepen­dent surgical groups are no longer private, and no longer independent. They have been swallowed by the corporate world.
Prof Haile Debas, on his presidential address titled “Surgery: A Noble Profession in a Changing World” given to the American Surgical Association, called surgery noble and quoted Webster’s Third New International Dictionary that denes the wordnoble as: (1) possessing outstanding qualities such as eminence, dignity; (2) having power of transmitting by inheritance; (3) indi­cating superiority or commanding excellence of mind, character, or high ide­als or morals. Further, Prof Debas continued: “These three attributes bet the profession of surgery. Over centuries, the surgical profession has set the stan­dards of ethical and humane practice. Surgeons have made magnicent con­tributions in education, clinical care, and science. Their landmark accomplishments in surgical science and innovations in operative technique have revolutionized surgical care, saved countless lives, and signicantly improved longevity and the quality of human life. Generations of surgeons have developed their craft and passed it on to succeeding generations, as they have to me and to each one of you, to take into the future.”
Practice of surgery has changed signicantly and dramatically, and sur­geons have become a replaceable workforce of major corporations, and worse
Prologue to Second Edition
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we have become “shift doctors” managed by several VPs in expensive suites that often have just come out of MBA schools and have no clue how surgery or department of surgery is run. Furthermore, as Prof Debas writes in the above-cited paper: “Financial control and control of access to healthcare were taken over by HMOs and insurance companies. As for-prot medicine proliferated, the health of our patients has come to be treated as a commodity traded daily on Wall Street. History will record that the medical profession was sidelined and watched haplessly as MBAs and business executives dened the fate of healthcare.” He calls these effects of HMO “deplorable.”
While director and chairman of a major medical center and academic department, I witnessed senior academic surgeons, deans, and other major academicians being “walked out” of the hospital or their ofces without any cause or explanation. They wanted to “move in a new direction.” The aca­demic surgeons and surgery itself once the “crème de la crème” of the hospi­tal have become under major corporate attacks in the last 2 to 3 decades. Unfortunately, this is not happening only in America. However, this hijacking of the surgical world by the corporate world should not cloud our thoughts and our surgical decisions, and we should make the best decision possible for every single patient that we evaluate and care for, by being trained well, being ready to care for every surgical disease. Surgeons as true leaders, should own the care of the patient, lead the multidisciplinary and complex care with pas­sion, love, and respect for everyone, and these affect people’s lives, save lives, and prevent morbidity.
The consequences may be because the surgeon decided to operate, or when the surgeon makes a decision not to operate, or not to operate in a timely fashion. As my former Professor of Surgery, Gazmend Shaqiri, a true (general, vascular, cardiothoracic) surgeon used to tell us students at the University of Prishtina, Kosova, “When a patient dies in a medical ward, he or she dies from the disease; however, when the patient dies in surgical ward, the patient dies from the surgery, or more importantly, of the decisions made by the surgeon.”
Every surgical decision that we make as surgeons may have consequences, and regrets that have been reported in about 1in 7 surgical patients (Loftus etal. 2020), both patient related and procedure related. Yet, despite this sur­gery was, and remains, the best clinical discipline, and represents both a sci­ence and art, and surgeons are the conductors of a symphony that truly needs to play perfectly. There are other somewhat more silent consequences of sur­gical decision-making.
In a study of almost 8 million patients, analyzed from the National Inpatient Sample data base, we found that delaying the operation and not performing in the optimal time was the most common cause of mortality (Smiley and Lati n.d). While we were unable to discern why the decision to operate was delayed, the decision to operate or not is the surgeon’s, and it is the decision not to operate that had major consequences. While surgical pro­cedures are far more complex than one individual’s decisions during surgery, there are elements to this small surgical microcosm that add additional pres­sure on the surgeon and how he or she copes with this decision. Over the
xx
years, I have been reminded often of the consequences of making a decision, both wrong and right.
I am hoping this book will serve as a good reference, or even inspiration, for others to explore the subject further and remind yourself what I teach everyone who listens—that “surgery is easy, the decision is not.” I did not and do not envision this as a book of a bunch of algorithms both from some great books on the subject, or created by AI, whose computers are major polluters of our environment, to create strict protocols, although in a couple of chapters such suggestions have been made. I wanted this book to go a bit “beyond” the glory of being a surgeon and at the soul of the surgical decision-making pro­cess, and inside the surgeon being, under his or her skin. I wanted to explore what makes the surgeon’s brain and heart “buzz,” and continue to work non­stop for many hours. While at Yale University, before the regulation of work­ing hours for residents, one of my vascular attendings and I operated basically nonstop from Friday morning until Sunday afternoon, with few “power naps” in the PACU or noisy operating room lounge between cases. When we n­ished Sunday afternoon, I thought I was doing “ne” until I went to start my car. Now that adrenaline was gone, I could not even drive myself home. I was completely exhausted and could not keep my eyes open. I had to call my wife Drita to come pick me up and take me home. How was I able to go on for so long while we were operating and yet I could not drive myself home the 10miles to Hamden?
The anatomy and the physiology of the surgeon are addressed in Chaps. 1 and 2. We cannot forget that we are not super creatures, despite what every­one may think of us; we are all just humans, like all others except we are leaders who really care.
Have you ever seen a surgeon emotionally “naked,” helpless, lonely, exhausted, disillusioned, and simply tired of everything? Even worse, most of us do not talk about the matter until it becomes real problem. Not a pretty picture by all means. At this point, you may be thinking of friends and col­leagues who committed suicide or were on the brink of doing so. Drug and alcohol abuse, difculties with personal relations, multiple divorces, or sim­ply becoming obese and not caring for oneself are not uncommon among us surgeons. We are just humans, and yet, like many other professions, we still have to get up and go to work and make some incredible decisions that will affect our patients and their families, and of course us, that we have to live with those decisions. Hopefully, this book will explain some of those deci­sions, and how we make them, but most importantly how we live with the decisions we make and how we improve constantly.
Prologue to Second Edition

Further Reading

Debas, Haile T. MD. Surgery: A Noble Profession in a Changing World.
Annals of Surgery 236(3):p 263–269, September 2002 Loftus TJ, Tighe PJ, Filiberto AC, Efron PA, Brakenridge SC, Mohr AM,
Rashidi P, Upchurch GR Jr, Bihorac A.Articial Intelligence and Surgical
Decision-making. JAMA Surg. 2020 Feb 1;155(2):148–158. https://doi.
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org/10.1001/jamasurg.2019.4917. PMID: 31825465; PMCID:
PMC7286802.
Abbas Smiley, Rifat Lati. The Role of Delayed Operation in Hospital
Mortality in Emergency General Surgery Admissions: A 10-year Study of 6,805,380 Patients. Unpublished data.
Wilson A, Ronnekleiv-Kelly SM, Pawlik TM.Regret in Surgical Decision
Making: A Systematic Review of Patient and Physician Perspectives. World J Surg. 2017 Jun;41(6):1454–1465. https://doi.org/10.1007/s00268-
017- 3895- 9. PMID: 28243695.
RifatLati

Contents

Part I Changing World and the Legacy of Surgical Decision-Making
1 Surgical Decision-Making and the Changing World . . . . . . . . . . 3
Rifat Lati and Abbas Smiley
2 Professor Rao Ivatury: A Legacy of Surgical Decision-Making
in Trauma Surgery, Excellence, Compassion, and Humility . . . 9
Rifat Lati
3 Surgical Decision-Making: More Questions than Answers? . . . . 15
Rifat Lati and Abbas Smiley
Part II The Complexity of Surgical Decision: Setting the Stage
4 The Anatomy of the Surgeon’s Decision-Making . . . . . . . . . . . . . 31
Rifat Lati and Abbas Smiley
5 The Role of the Surgeon’s Physiology and the State of Mind
in the Surgical Decision-Making Process: An Update . . . . . . . . . 41
Rifat Lati and Abbas Smiley
6 Surgeons and Pilots: What Do We Have in Common? . . . . . . . . 49
Rifat Lati
7 Planning and Preparing for the Operation: The Role of
Artificial Intelligence in Modern Surgery. . . . . . . . . . . . . . . . . . 57
J. Esteban Foianini and Genna Beattie
8 Decision-Making in Critical Care Rescue for Re-operative
Surgery . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 69
Diane N. Haddad and Gary A. Bass
Part III Surgical Decision Making in Difcult Scenarios of Acute
Care Surgery
9 Surgical Decision-Making in Postinjury Multiple Organ
Failure . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 83
Ryan S. Ting, Kate L. King, and Zsolt J. Balogh
xxiii