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22 Basic Otological Surgical Techniques
Periodic cleaning of the EAC and mastoid cavity is required in the postoperative follow-up as the anatomy and physiological cleaning of the cavity cannot be pre­served with the CWD approach. Hearing aid amplication and the effects of exter­nal physical factors are the main obstacles in the mastoid cavity.
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22.4.4 Retrograde Mastoidectomy
Retrograde mastoidectomy (inside-outside) is a type of combined CWD mastoidec­tomy approach. This approach, described by Dornhoffer [12], is used in cases of cholesteatoma limited to the attic, epitympanum, and upper mesotympanum. The EAC is partially lowered with a burr, starting from the attic and following the dis­ease posteriorly and superiorly. This technique allows limited removal of the attic cholesteatoma and reconstruction of the ossicular chain. The defect in the EAC wall is closed with palisade-shaped cartilage. Similar cholesteatoma recurrence rates of 5–10% have been observed when comparing cases operated with the retrograde mastoidectomy approach and CWD mastoidectomy [13].
22.4.5 Modified Radical Mastoidectomy
The modied RM (MRM) approach involves removal of the posterior and superior walls of the EAC, like CWD mastoidectomy, terminologically, CWD mastoidec­tomy and MRM are often used to refer to the same surgical technique. The Bondy approach [14], which is less commonly used today, involves the removal of disease from the attic and mastoid cavity in limited cholesteatomas that do not extend to the middle ear. Fascial grafts are placed lateral to the head of the malleus and the body of the incus and mastoid cavity without involving the middle ear.
22.4.6 Radical Mastoidectomy
The RM approach is also a CWD procedure. In contrast, RM does not preserve middle ear function, removes malleus and incus, and closes the Eustachian tube. No fascial or cartilaginous grafts are placed, allowing the epithelial lining of the entire middle ear and mastoid cavity to remain intact.
22.4.7 Mastoid Obliteration
This approach aims to reduce the size of the mastoid cavity in cases such as CWD, MRM, and retrograde mastoidectomy where the canal wall is lowered. This makes it easier to obliterate the mastoid cavity and amplify the device in patients who use postoperative cavity care and hearing aids. LSSC is exposed to external factors in an open cavity. Obliteration may be indicated in recurrent skin infections or when
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thermal changes, wind, or water exposure cause dizziness or vertigo. Autologous materials used for obliteration include bone pate, bone chips, minced cartilage, muscle ap, and fat, and allograft materials include hydroxyapatite bioactive glass and tricalcium phosphate. Palva [15, 16] rst described ap obliteration by placing postauricular pedicled musculoperiosteal tissue into the mastoid cavity.

22.5 Petrosectomy

The most common pathologies affecting the petrous apex include cholesterol granu­loma, cholesteatoma, aneurysm, asymmetric aeration and presence of bone marrow, arachnoid cyst, petrous apicitis (Gradenigo syndrome), mucocele, and petrous apex effusion. Surgical intervention may be required in symptomatic cases that do not respond to conservative management. Several surgical approaches can be used for petrous apex lesions depending on the surgeon’s experience, the location of the lesion in the petrous bone, and the preservation of hearing. Approaches to the petrous apex include transcanal infracochlear, transmastoid infralabyrinthine, mid­dle fossa craniotomy, translabyrinthine, suboccipital, transsphenoidal endoscopic, and infratemporal fossa (ITF) types A and B.

22.6 Conclusion

The primary purpose of all otological techniques dened in COM surgery is to remove the disease that may cause complications from the middle ear and associ­ated mastoid region or to manage the complication that occurs before surgery. The secondary purpose is hearing reconstruction through ossiculoplastic interventions by creating a ventilated and functional middle ear cavity. For these purposes, the microscope has long been used in all otological surgical interventions. In addition, recently the transcanal endoscopic approach, both in combination with microscopic surgery and alone, has become popular in the eld of otology. Although endoscopic ear surgery requires a more difcult learning process and experience than micro­scopic surgery. Since it is less invasive and provides an easier healing period, it will be the preferred method in the eld of otology in the future.

References

1. Zhang LC, Zhang TY, Dai PD, Luo JF.Titanium versus non-titanium prostheses in ossicu­loplasty: a meta-analysis. Acta Otolaryngol. 2011;131(7):708–15. https://doi.org/10.310
9/00016489.2011.556662. Epub 2011 Apr 15. PMID: 21492071.
2. Ho SY, Battista RA, Wiet RJ.Early results with titanium ossicular implants. Otol Neurotol. 2003;24(2):149–52. https://doi.org/10.1097/00129492- 200303000- 00005. PMID: 12621325.
3. House JW, Teufert KB. Extrusion rates and hearing results in ossicular reconstruction. Otolaryngol Head Neck Surg. 2001;125(3):135–41. https://doi.org/10.1067/mhn.2001.117163. PMID: 11555743.
22 Basic Otological Surgical Techniques
4. Grote JJ.Reconstruction of the middle ear with hydroxylapatite implants: long-term results. Ann Otol Rhinol Laryngol Suppl. 1990;144:12–6. PMID: 2154156.
5. Truy E, Naiman AN, Pavillon C, Abedipour D, Lina-Granade G, Rabilloud M.Hydroxyapatite versus titanium ossiculoplasty. Otol Neurotol. 2007;28(4):492–8. https://doi.org/10.1097/01.
mao.0000265203.92743.d1. PMID: 17529851.
6. Yung M, Vowler SL.Long-term results in ossiculoplasty: an analysis of prognostic factors. Otol Neurotol. 2006;27(6):874–81. https://doi.org/10.1097/01.mao.0000226305.43951.13. PMID: 16788423.
7. Kalcioglu MT, Ozerk A, Egilmez OK, Kokten N, Uzun L, Toplu Y, Tekin M.Mastoid cavity obliteration with cartilage graft; evaluation of 35 patients. Medeni Med J. 2019;34(4):360–7.
https://doi.org/10.5222/MMJ.2019.60948.
8. Shambaugh GE, Glasscock ME.Surgery of the ear. Philadelphia: Saunders; 1980.
9. Book review: The modern mastoid operation. Ann Otol Rhinol Laryngol. 1905;14(1):210–1.
https://doi.org/10.1177/000348940501400117.
10. Brackmann DE.Tympanoplasty with mastoidectomy: canal wall up procedures. Am J Otol. 1993;14(4):380–2. PMID: 8238275.
11. Jansen C. The combined approach for tympanoplasty (report on 10 years’ experience). J Laryngol Otol. 1968;82(9):779–93. https://doi.org/10.1017/s0022215100069462. PMID:
4878658.
12. Sheehy JL, Patterson ME. Intact canal wall tympanoplasty with mastoidectomy. A review of eight years’ experience. Laryngoscope. 1967;77(8):1502–42. https://doi.
org/10.1288/00005537- 196708000- 00018. PMID: 6034865.
13. Dornhoffer JL. Retrograde mastoidectomy. Otolaryngol Clin N Am. 2006;39(6):1115–27.
https://doi.org/10.1016/j.otc.2006.08.002. PMID: 17097436.
14. Bondy G. Totalaufmeisselung mit Erhaltung von Trommefell und Gehork nochelchen. Monatsschr Ohrenheilkd. 1910;44:15–23.
15. Palva T.Operative technique in mastoid obliteration. Acta Otolaryngol. 1973;75(4):289–90.
https://doi.org/10.3109/00016487309139718. PMID: 4702622.
16. Palva T. Mastoid obliteration. Acta Otolaryngol Suppl. 1979;360:152–4. https://doi.
org/10.3109/00016487809123502. PMID: 377902.
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Tympanoplasty

23
IsaKaya, TayfunKirazli, andJohnL.Dornhoffer

23.1 Introduction

Tympanoplasty is a surgical procedure that aims to reconstruct the tympano­ossicular system. The primary goal of this procedure is to remove diseased tissue from the tympanic membrane (TM) and middle ear cavity, reconstruct the tympano­ossicular structures, and create a functional, closed cavity that is aerated. The sec­ondary goal is to improve the patient’s hearing as much as possible.
Tympanoplasty can be broadly divided into four categories: myringoplasty, ossiculoplasty, canaloplasty, and meatoplasty. Myringoplasty is the surgical reconstruction of the TM.The goal of myringoplasty is to restore the ability of the TM to vibrate, which is necessary for hearing. Ossiculoplasty is the surgical reconstruction of the ossicular chain. The ossicular chain comprises the malleus, incus, and stapes, which transmit sound waves from the TM to the inner ear. Ossiculoplasty is performed when the ossicular chain is damaged and prevents sound waves from reaching the inner ear. Canaloplasty is the surgical restoration of the normal width and contour of the ear canal. Canaloplasty is performed to improve the patient’s ability to clean the ear canal and to facilitate a second-stage ossiculoplasty, if necessary. Meatoplasty is the surgical widening of the cartilagi­nous ear canal relative to the diameter of the medial bony canal. Meatoplasty is performed to improve the patient’s hearing by increasing the surface area of the TM exposed to sound waves.
I. Kaya (*) · T. Kirazli Faculty of Medicine, Department of Otorhinolaryngology, Ege University, Izmir, Turkey
J. L. Dornhoffer Arkansas Children’s Hospital, Department of Otolaryngology/Head and Neck Surgery, University of Arkansas for Medical Sciences, Little Rock, AR, USA e-mail: dornhofferjohnl@uams.edu
© The Author(s), under exclusive license to Springer Nature Switzerland AG 2024 M. T. Kalcioglu et al. (eds.), Otology Updates, Comprehensive ENT,
https://doi.org/10.1007/978-3-031-76173-7_23
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23.2 Etiology ofTM Perforations
23.2.1 Chronic Otitis Media
Chronic otitis media (COM) is a disease characterized by persistent or recurrent episodes of acute otitis media lasting more than 12weeks, typically culminating in a nonhealing perforation of the TM [1]. Affecting more patients worldwide than any other infectious disease [2], the development of COM is inuenced by multiple risk factors, including upper respiratory tract infections, malnutrition, poor hygiene, familial predisposition to ear infections, low birth weight, craniofacial anomalies, and ethnic background, particularly in populations of Native American, Native Alaskan, and Aboriginal Australian descent [3].
The cardinal symptoms of COM are otorrhea, discharge leakage through the per­forated TM into the external ear canal, and hearing loss [4]. The latter typically mani­fests as a mild conductive decit in the range of 10–20 decibels (dB). However, larger perforations can result in more signicant hearing impairment. Ossicular chain erosion, a potential complication, can further exacerbate audiologic decits, result­ing in a loss of 50–70 dB. In such cases, careful evaluation for cholesteatoma is crucial, as its presence signicantly complicates both management and prognosis [4].
Tympanic membrane perforations (TMP) can be classied according to their location, size, and presence of drainage. The vast majority occur in the pars tensa, while the pars accida is less commonly involved [5]. Based on their location rela­tive to the annulus, perforations can be classied as marginal or central [6]. In addi­tion, the presence or absence of active otorrhea (persistent discharge) denes them as wet or dry [6]. This classication system is crucial for guiding appropriate treat­ment strategies, as different types of perforations may require different surgical approaches or medical interventions [5, 6].
Tympanoplasty remains a cornerstone procedure in the management of chronic otitis media with the dual goals of eradicating infection and restoring TM integrity [7]. The two goals of this surgical procedure are to achieve an intact TM and improved hearing function [8]. Reconstruction of the perforated TM by graft place­ment is the core of tympanoplasty, as complete TM healing is the basis for establish­ing a healthy middle ear environment free of chronic inammation and infection [9].
23.2.2 Traumatic Perforations
The TM can be injured by both direct or indirect forces. Direct trauma can result from a blow to the ear, a foreign body penetrating the TM, or direct exposure of the TM to heat or ame. Indirect trauma can result from a skull fracture, either with or without a temporal bone fracture. Longitudinal skull fractures can injure the TM and other middle ear structures. Sounds of 195dB or greater can cause acoustic trauma that can damage the TM.Sudden changes in pressure can cause barotrauma, which can also damage the TM.Disruption of the ossicular chain and window stu­las may occur, especially after traumatic perforation of the TM.
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23.3 History ofTympanoplasty
The history of tympanoplasty reveals a dynamic evolution of graft materials. Pioneering efforts by Banzer in 1640 used pig bladder, followed by Blake’s paper patch in 1877 and Berthold’s rst skin graft in 1878 [1012]. Microscopic tympa­noplasty with skin grafts became the dominant technique in the 1950s [13]. Soon after, canal skin pedicle grafts were introduced to repair extensive perforations [13]. Vein grafts gained traction in the late 1950s, and House and Sheehy provided further innovations with canal skin overlay grafts in the early 1960s [13, 14]. Storrs’ land­mark report in 1961 described the fascia graft technique, adding another valuable option to the growing repertoire [15].
Tympanoplasty techniques have evolved over time and include approaches such as overlay, underlay, and over-underlay procedures [14, 16]. While microscopic tympanoplasty has dominated since the 1950s, endoscopic techniques have gained popularity since the 1990s [17, 18]. This diversity extends to graft materials, with temporalis muscle fascia remaining the most common choice due to its approxi­mately 90% success rate in primary tympanoplasties [19, 20]. However, there is concern for larger perforations where success rates have been reported to decrease [21]. A possible explanation lies in the unpredictable shrinkage of the fascia, which is attributed to its disorganized arrangement of elastic bers and interspersed brous connective tissue, with the latter exhibiting greater shrinkage than elastic bers [22]. This highlights the need for further investigation of alternative materials and techniques to optimize tympanoplasty outcomes, particularly for challenging cases.
In 1963, cartilage emerged as a promising alternative to temporalis fascia for TM reconstruction, especially in difcult cases [23, 24]. Unlike fascia, which is free of unpredictable brous components, cartilage has an inherent stiffness that resists resorption and retraction even in chronic Eustachian tube (ET) dysfunction [25]. This superior structural stability increases its attractiveness, not only in advanced middle ear pathologies but also in subtotal or total perforations. However, the rigid­ity of the cartilage has sparked debate regarding its impact on audiological out­comes [26]. Therefore, meticulous preoperative assessment of the degree and type of hearing loss, including the potential detection of occult pathology, is crucial to optimize material selection and surgical planning.
23.4 Anatomy andPhysiology
The middle ear cleft, also termed the tympanic cavity, resides within the petrous portion of the temporal bone. It houses key anatomical structures, including the inner layer of the TM, the ET orice, and the three ossicles (malleus, incus, stapes) that form the ossicular chain. Posteriorly, the middle ear cleft communicates with the mastoid air cell system via the tympanic antrum and the aditus ad antrum. This connection facilitates aeration and pressure equalization. Anteriorly, the ET con­nects the middle ear cavity to the nasopharynx, allowing for pressure equalization with the environment.
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The TM forms most of the lateral wall of the middle ear. This tri-layered structure has unique properties that are critical for sound transmission. The outermost layer, a seamless extension of the external auditory canal epithelium, consists of stratied squamous epithelium. The middle layer, the brous stratum (lamina propria), repre­sents the core and primary determinant of TM stability. Robust collagen bers travers­ing this layer limit stretchability, enabling the TM to exhibit high compliance at minimal acoustic pressure displacements while resisting excessive stretching at higher pressures. This compliance allows for efcient sound transmission. Finally, the inner­most layer, which is continuous with the cuboidal middle ear mucosa, completes the composite structure. The collagen bers of the brous stratum play a critical role in regulating compliance, ensuring that the TM responds effectively to changes in acous­tic pressure. Approximately 10mm in diameter and 0.1mm thick, the TM typically appears pearly gray and slightly translucent, allowing visualization of the underlying ossicular chain. This transparency facilitates clinical assessment and diagnosis [27].
The TM exhibits a distinct topographic division. The pars accida, located anteri­orly and posteriorly to the malleolar ligaments, occupies the superior region. This area lacks the central brous layer of the pars tensa, making it thinner and more compliant. As a result, the pars accida has greater exibility and responsiveness to acoustic pres­sure than the more rigid, brous pars tensa, which makes up the majority of the TM and covers the area below the neck of the malleus. In clinical practice, the TM is further subdivided into four quadrants for precise localization. These quadrants are delineated by horizontal and vertical lines intersecting at the umbo and passing through the handle of the malleus. A comprehensive understanding of these intricate spatial relationships within the middle ear is crucial for the otologic surgeon, as both functional and ana­tomical considerations signicantly inuence surgical approaches [5].
The TM and the ossicular chain serve as the exquisitely designed sound trans­mission apparatus of the middle ear. Airborne sound waves, manifested as air pres­sure uctuations, impinge on the TM, initiating a cascade of mechanical energy transfer [28, 29]. This energy transmission unfolds via the ossicular chain, a series of intricately linked ossicles—the malleus, incus, and stapes—that amplify the incoming signal. The amplied mechanical vibrations are delivered to the oval win­dow of the inner ear, ultimately creating a uid wave within the cochlea [29]. This uid wave interacts with specialized hair cells organized tonotopically on the basi­lar membrane, triggering the conversion of mechanical energy into electrical nerve impulses [30]. These neural signals, encoded with auditory information, are then transmitted via the cochlear nerve to the brainstem, completing the remarkable jour­ney of sound from the outside world to the central nervous system.
Hearing losses that occur in the case of TMP are shown in Table23.1.
Table 23.1 Hearing loss resulting from total membrane perforation and ossicular chain dislocation
Lack of leverage 7.3dB Lack of hydraulic effect 26.5dB Elimination of phase
protection effect Total loss 50dB
16.2dB
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23.5 Tympanoplasty Types

According to the classication made by Wullstein in 1956, there are ve types of tympanoplasty [31]. The methods are named according to the condition of the ossicles.
Wullstein Classication (Adapted from Reference [31])
• Type I: There is no problem in the middle ear and ossicles. Only the TM is
repaired. It is synonymous with myringoplasty.
• Type II: There is a defect in the malleus. The graft is placed on the incus.
• Type III: There is erosion of the malleus and incus. The graft is placed on the
suprastructure of the stapes.
• Type IV: The ossicles are eroded except for the base of the stapes. The graft is
placed on the stapes foodplate, which is mobile.
• Type V: The stapes base is xed. The fenestration is made and the graft is placed.
The Bellucci classication is based on the discharge in the middle ear [32].
Bellucci Classication (Adapted from Reference [32])
• Group I.The ear has been stable for a long time. The prognosis is good.
• Group II.The middle ear is stable, but discharge develops during upper respira-
tory tract infections. The middle ear is sometimes dry and sometimes wet. The
prognosis is fair.
• Group III.There is a constant discharge from the ear. There is no period when the
middle ear is dry. It may be mastoiditis. The prognosis is poor.
• Group IV.There is a persistent discharge from the ear accompanied by nasopha-
ryngeal problems such as cleft palate or choanal atresia. The prognosis is
very poor.
23.6 Perforation Size andLocation
Based on the percentage of the TM surface that is perforated, TMPs are classied as small, medium, subtotal, and total (⩽25%, ⩽50%, ⩽75%, and 76%, respectively). The severity of conductive hearing loss, a hallmark consequence of TMPs, has been shown to increase with the size and duration of the perforation [33]. In addition, subtotal and total perforations have limited self-healing potential and provide fewer suitable sites for graft adherence during surgical repair [34]. Reconstruction of total TMPs presents the most signicant challenge in tympanoplasty due to the complete absence of the annular remnant that serves as the primary vascular bed for the graft. Therefore, the choice of surgical approach depends on the condition of the protym­panum. In cases with intact protympanic mucosa, the underlay technique utilizing the mucosa as a vascular bed can be employed. Conversely, in situations where the protympanum is obliterated or signicantly compromised, the overlay technique may be required. Interestingly, spindle-shaped perforations have been shown to
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disproportionately disrupt sound conduction compared to circular perforations, especially at high frequencies [33]. These observations underscore the signicance of perforation size, shape, and chronicity in determining both the degree of hearing impairment and the success of reparative interventions.
TMP classication based on location includes posterior, anterior, marginal, median, and attic perforations. Notably, marginal and attic perforations carry a higher risk of retraction and cholesteatoma development compared to median per­forations, raising safety concerns [35]. This increased risk in marginal and attic locations stems from their vulnerability to retraction, a process in which the TM is pulled inward, creating a potential pocket for debris accumulation and subsequent cholesteatoma formation. In contrast, median perforations, which are centrally located, exhibit a lower propensity for retraction and cholesteatoma development. However, their location, particularly around the umbo/manubrium region, can sig­nicantly impact sound transmission through the middle ear, resulting in signicant conduction disturbances [36, 37]. Additionally, anterior and marginal perforations present surgical challenges due to limited graft attachment sites and anatomical constraints. The transcanal approach commonly used for tympanoplasty is often hampered by the narrower ear canal, angular TMP, and medial canal curvature asso­ciated with these perforations, compromising surgical access.
The anatomical limitations of certain perforation sites, particularly anterior and marginal sites, pose signicant challenges to surgical reconstruction using the trans­canal approach. As a result, surgeons may opt for more invasive alternatives such as postaural and endaural approaches to ensure optimal graft placement [5, 38]. The choice of approach ultimately depends on the specic anatomic features of the per­foration and the surrounding ear structures. By carefully considering these factors, surgeons can ensure effective and safe material placement to maximize the success of the TM repair.
Perforations extending into the anterior quadrants require meticulous graft place­ment to avoid complications. To prevent anterior blunting, the graft should be posi­tioned deep to the anterior portion of the annulus, effectively tucked under the bony ring. However, lateralization must also be avoided. Therefore, the graft should be placed medial to the manubrium mallei to ensure proper positioning. In addition, it is critical that the graft adequately covers the posterior wall to ensure intimate con­tact with the remaining TM and middle ear mucosa.

23.7 Graft Materials

Tympanoplasty is essentially a tissue transfer procedure aimed at reconstructing the TM.Surgeons have a repertoire of graft materials at their disposal, each with differ­ent characteristics that inuence their suitability for different scenarios. Temporalis fascia remains the mainstay of choice due to several advantages. Located in close proximity to the surgical site, temporalis fascia offers ease of harvest with minimal donor site morbidity. Its inherent properties, characterized by a dense collagenous structure and low vascularity, contribute to excellent stability and minimal
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shrinkage after grafting. This makes it ideal for primary tympanoplasty, promoting successful long-term TM closure and improved hearing outcomes [23, 39]. However, some surgeons prefer to use the loose areolar fascia of the temporalis muscle, espe­cially in revision cases or when true fascia needs to be preserved for future proce­dures. This alternative offers comparable ease of harvest but with increased vascularity, requiring careful selection in specic cases where graft vascularity may be a concern [40]. The popularity of cartilage grafts has increased dramatically over the past few decades. The ease of harvesting from the tragus or concha of the auri­cle, coupled with promising results in numerous studies, has fueled this trend [40,
42]. Cartilage grafts have several potential advantages. Their limited size minimizes
donor site morbidity, while their inherent rigidity and resistance to resorption pro­vide superior structural support compared to fascial grafts. This robustness makes them an attractive option for complex perforations with a history of failed repair [40, 41]. In addition, the passive diffusion of nutrients offered by cartilage may contribute to higher graft acceptance rates [43]. However, concerns regarding the effect of cartilage on sound transmission due to reduced sound conductivity com­pared to other materials have sparked ongoing debate.
Full-thickness cartilage grafts may actually cause some hearing loss compared to other materials due to their stiffness [44]. Fortunately, research suggests that this can be mitigated by utilizing partial-thickness grafts, which have been shown to improve hearing outcomes [45]. Interestingly, despite initial concerns regarding potential conductive hearing loss associated with cartilage thickness, several studies have reported surprisingly positive results [46]. Evidence from both experimental and clinical studies indicates comparable hearing outcomes with cartilage and fas­cia grafts [40, 42, 47]. In particular, the middle ear appears to tolerate cartilage well, with long-term graft survival consistently observed. These ndings challenge previ­ously held concerns about the impact of cartilage on hearing and suggest that its use as a graft material is not inherently detrimental to auditory function compared to alternatives such as fascia.
The growing body of literature documenting favorable outcomes with cartilage grafts in tympanoplasty underscores their efcacy and durability as a middle ear reconstruction material [48, 49]. To achieve this reconstruction, surgeons imple­ment two different techniques: the perichondrium/cartilage island ap and the pali­sade technique. Each technique offers distinct advantages that require careful consideration during surgical planning. The selection of the optimal technique depends on a nuanced understanding of the specic middle ear pathology, the con­dition of the ossicular chain, and the experience of the surgeon.
Ultimately, the optimal choice of graft material depends on careful consideration of several factors: the surgeon’s expertise and preference, the unique characteristics of the perforation (size, location, chronicity), and whether the procedure is a pri­mary or revision surgery. The variety of options available, including temporalis fas­cia, cartilage, perichondrium, and various composites, allows surgeons to tailor their approach to the specic needs of each case, maximizing the success of the tympanoplasty and ultimately improving patient outcomes [41]. A listing of poten­tial graft materials is provided in Table23.2.