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©2013 Kaplan, Inc.

Allrights reserved. No part of this book may be reproduced in any form, by photostat, microfilm, xerography or any other means, or incorporated into any information retrieval system, electronic or mechanical, without the written permission of Kaplan, Inc.

Not for resale.

Authors

James White, Ph.D.

Assistant Professor of Cell Biology

School of Osteopathic Medicine

University of Medicine and Dentistry of New Jersey

Stratford, NJ

Adjunct Assistant Professor of Cell and Developmental Biology

University of Pennsylvania School of Medicine

Philadelphia, PA

David Seiden, Ph.D.

Professor of Neuroscience and Cell Biology

Senior Academic Advisor to the Dean

Rutgers-Robert Wood Johnson Medical School

Piscataway, NJ

Contents

Preface . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . vii

Section I: Histology and Cell Biology

 

Chapter 1: Cell Biology and Epithelia ..........................

3

Chapter 2: Connective Tissue ...............................

27

Chapter 3: Cartilage and Bone ..............................

35

Chapter4: Muscle Tissue...................................

45

Chapters: Nervous Tissue..................................

55

Chapter 6: Immune Tissues.................................

65

Chapter 7: Respiratory System ..............................

77

Chapter 8: Gastrointestinal System...........................

87

Chapter 9: Urinary System..................................

115

Chapter 10: Male Reproductive System ......................

125

Chapter 11: Female Reproductive System ....................

139

Chapter 12: Integument...................................

149

Section11: Early Embryology

 

Chapter 1: Gonad Development............................

155

Chapter 2: Week 1: Beginning of Development.................

161

Chapter 3: Week 2: Formation of the Bilaminar Embryo ........

163

Chapter 4: Embryonic Period (Weeks 3-8) ...................

165

MEDICAL

V

Section Ill: Gross Anatomy

Chapter 1: Back and Autonomic Nervous System . . . . . . . . . . . . . . . 171

Chapter 2: Thorax.. . . ... . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 185

Chapter 3: Abdomen, Pelvis, and Perineum. . . . ... . . .. . .......

231

Chapter 4: Upper Limb . . .. . . ... . . .. . . . . . . . . . . . . . . . . . . . . . .

285

Chapter 5: Lower Limb . . . .. . . . ... . .. . . . .. . . . . . . . . . . . . . . . .

301

Chapter 6: Head and Neck . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

. 313

Section IV: Neuroscience

 

Chapter 1: Nervous System . .. . . .. . . . . . . . . . . . . . . . . . . . . . . ...

333

Chapter 2: Central Nervous System . . . . . .. . . . . . . . . . . . . . . . . . .

345

Chapter3: Ventricular System . .............................

351

Chapter4: The Spinal Cord................................

357

Chapter 5: The Brain Stem. . . . . . .. . . . ... . . . . . .. . . . . . . . . . . . .

383

Chapter 6: The Cerebellum . . . . . . . . . . . . . . . .. . . . ... . . . . . . . . .

421

Chapter 7: Basal Ganglia. . . . . . . . . . . . . . . . . .. . . . . .. . . . . . . . . .

429

Chapter 8: Visual Pathways . . . . . . . . . . . .. . . . . . . . . . . . . . . .. . . .

437

Chapter 9: Diencephalon. . . . .. . . . . . . . . . . . . . . . . . . . . . . . . . . . .

447

Chapter 10: Cerebral Cortex . . .. . . . .. . . ... . . . .. . . . ... . . . . . .

455

Chapter 11: Limbic System . ........... . ...................

475

Index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

481

Vi MEDICAL

Preface

These 7 volumes of Lecture Notes represent the most-likely-to-be-tested material on the current USMLE Step 1 exam. Please note that these are Lecture Notes, not review books. The Notes were designed to be accompanied by faculty lectures­ live, on video, or on the web. Reading them without accessing the accompanying lectures is not an effective way to review for the USMLE.

To maximize the effectiveness of these Notes, annotate them as you listen to lec­ tures. To facilitate this process, we've created wide, blank margins. While these margins are occasionally punctuated by faculty high-yield "margin notes:' they are, for the most part, left blank for your notations.

Many students find that previewing the Notes prior to the lecture is a very effec­ tive way to prepare for class. This allows you to anticipate the areas where you'll need to pay particular attention. It also affords you the opportunity to map out how the information is going to be presented and what sort of study aids (charts, diagrams, etc.) you might want to add. This strategy works regardless of whether you're attending a live lecture or watching one on video or the web.

Finally, we want to hear what you think. What do you like about the Notes? What could be improved? Please share your feedback by e-mailing us at medfeedback@ kaplan.com.

Thank you for joining Kaplan Medical, and best of luck on your Step 1 exam!

Kaplan Medical

MEDICAL

Vii

SECTION

Histology and

Cell Biology