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CHAPTER 7 Physiologic Monitoring
Catheter length (cm)
12
Total body length (cm)
58
Catheter length (cm)
22
Total body length (cm)
T8
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169
L5 L3
10
8
6
4
28
30 32 34 36 3840 42 44
FIGURE 7.3 Graph for distance of catheter insertion from umbilical ring for
low placement. (From Rosenfeld W, Biagtan J, Schaeffer H, et al. A new graph for insertion of umbilical artery catheters. J Pediatr. 1980;96(4):735.)
Dunn (bifurcation)
46 48 50 52 54 56
of extremely low-birth-weight (ELBW) infants. Catheters used to cannulate the umbilical vein are available as both single-lumen and double-lumen items. Double-lumen catheters permit the simulta­neous administration of infusates and medications. Use of a UVC reduces the need for peripheral devices when multilumen UVCs are used.
INTERVENTIONS
Invasive Monitoring
Placement of UACs or UVCs and placement of a peripherally inserted central catheter (PICC) are invasive monitoring techniques.
Umbilical Artery Catheter Placement
PROCEDURE
Determine the size and length of the catheter to be inserted. For infants weighing more than 1250 g,
use a 5-Fr catheter, and for infants weighing less than 1250 g, use a 3.5-Fr catheter. Figs. 7.3 and
7.4 correlate total body length with the length of
the catheter to be inserted. Whereas these charts have worked reasonably well in larger preterm and term infants, the Wright formula (4 × birth weight in kilo­grams + 7) resulted in significantly better placement in VLBW infants.
22,29
A comparison of formulas for the length of UAC placement found superior correct placement of the tip of the catheter with use of the Wright formula.
29
20 18 16 14 12 10
8 6 4 2 0
30 34 38 42
FIGURE 7.4 Graph for distance of catheter insertion from umbilical ring for
high placement (T8). (From Rosenfeld W, Estrada R, Jhaveri R, et al. Evalua­tion of graphs for insertion of umbilical artery catheters below the diaphragm. J Pediatr. 1981;98(4):627.)
46 50 54 58
Place the infant in a supine position on a radiant warmer bed or in an incubator. Ensure contin­uous temperature monitoring. Skin temperature should remain between 36°C and 37°C (96.8°F and 98.6°F). Provide appropriate oxygenation and ventilation. Ensure cardiorespiratory and oxygen saturation monitoring. Restrain the infant’s hands and feet to prevent him or her from contaminating the sterile field and interfering with the placement procedure. Don cap and mask. Open the catheter­ization tray; most units now use commercially avail­able disposable trays. Catheterization tray contents are shown in Fig. 7.5. Wash hands and dry with sterile towel before the procedure. Put on sterile gown and gloves.
Connect the catheter to the stopcock, and flush and fill the entire system, including the catheter, with flush solution. Turn off the stop­cock to the catheter to prevent fluid from draining out of the catheter during insertion and securing of the catheter. Cleanse the cord and base of the umbilicus with either povi­done-iodine or chlorhexidine with alcohol three times and allow the site to air-dry.33 Remove the povidone-iodine with alcohol. For infants weighing less than 1000 g, utilize sterile water.
Avoid using an excess of skin disinfectant so the infant is not lying in the solution during the procedure. Any residual skin disinfectant should be washed off the infant carefully after the procedure is completed.
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FIGURE 7.5 Argyle umbilical vessel catheter insertion tray. (Courtesy Tyco/Healthcare Kendall-LTP.)
Drape the infant by placing an eye sheet over the umbilicus. An alternative method is to use sterile drapes, as follows:
1. Hold the diagonal corners of one drape, and
allow the top half to fold over the bottom half.
The result is a V shape.
2. Place the tips of the V on either side of the
umbilicus.
3. Repeat with another drape, and place on the
other side of the umbilicus. The umbilical stump
is now visible yet surrounded by drapes.
After the UAC is inserted, the drapes can be removed easily without the need to pass the stop­cock and catheter through an eyehole of a drape or cut or tear the eyehole drape. Ensure that the
infant’s head and feet remain visible during the procedure to assess color. A small eye drape
with adhesive backing (such as a Steri-Drape) has the advantage of being transparent, so that the infant’s color can be seen, and temperature can be maintained. Towel drapes may interfere with a radiant heat source used for temperature regulation.
Place an umbilical cord tie (e.g., umbilical cord tape) around the base of the cord to control bleeding. A single overhand knot is preferred because it allows
tightening as needed. Using tissue forceps, pick up the cord and cut it with a scalpel about 1 to 1.5 cm above the base. Arterial spasm allows only minimal bleeding. Identify the vessels. There are usually two
arteries and one vein. The arteries are small, thick walled, and constricted. The vein is larger, thin walled, and usually gaping open. If the vein is at
the 12-o’clock position, the arteries are usually at the 4- and 8-o’clock positions (Fig. 7.6).
Stabilize the umbilical stump by grasping the cord between the thumb and index finger or grasping the edge of the stump with a mosquito hemostat. Ensure that the hemostat does not crush the umbilical vessels. With iris forceps, dilate one of the arteries by placing the tips of the forceps in the artery and gently allowing them to spring open. This procedure may need to be repeated several times. In ELBW infants, the artery may be so small that it may be necessary to initially insert one forcep tip and then both to dilate the artery. While grasping one side of the wall of the dilated artery with small forceps, gently insert the cathe­ter. An alternative method is to insert the catheter between the open prongs of the forceps used to dilate the artery. Instructional aids such as Baby Umb (Medical Plastics Laboratory, Inc., Gatesville,
Umbilical tape
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Umbilical
vein
Umbilical
arteries
FIGURE 7.6 Umbilical tape and position of umbilical vessels.
CHAPTER 7 Physiologic Monitoring
171
TX) and the Umbilical Artery Catheterization Slide-Tape Neonatal Educational Program (Charles R. Drew Postgraduate Medical School, Los Angeles, CA) are helpful. As the catheter passes into the artery, resistance may be encountered at several points, as follows:
• At the umbilical cord tie (tape): The tie (tape) may be tied too tightly. Loosen slightly.
• At the point at which the umbilical artery turns downward (caudal) into the abdomen: Steady, gentle pressure is important because forceful pressure may cause the catheter to perforate the artery wall and create a false channel.
• At the point at which the umbilical artery joins the external iliac artery: Once again, steady, gen­tle pressure is important. Insert the catheter to the predetermined length.
Aspiration on the syringe should provide immediate blood return. Lack of blood return may indicate the following:
• The catheter is not inserted far enough. Insert farther.
• The vessel wall has been perforated, or a false channel has been created. If the catheter has pierced the vessel wall, repeat the procedure using the other artery.
• The catheter is kinked. Pull back slightly and then advance.
• The stopcock is turned off. Correct the stopcock position. Return aspirated blood to the infant; then clear the catheter with flush solution.
There are several methods to secure the catheter,
including suturing to the umbilical stump, use of an
FIGURE 7.7 Umbilical artery catheter secured in “goalpost” design.
adhesive-type tape after using skin prep to protect the skin, use of a “goalpost” (Fig. 7.7), and use of sterile transparent dressing. The literature denotes these methods, but there is no evidence to delineate the most beneficial method. Advantages and disad­vantages of each method including skin issues, cost, and ease of use need to be researched.
14
Connect the stopcock to the intravenous (IV) solution, and set the prescribed infusion rate on the infusion pump. Ensure that no air is in the tub­ing, stopcock, or catheter. All connections must be secure. Automatic infusion pumps must be used for UACs because arterial pressure must be overcome to permit IV fluid infusion. Determine catheter placement by a radiologic examination (abdominal, chest, “babygram,” or ultrasound depending on placement of the catheter). Fig. 7.8 shows how the UAC appears on a lateral x-ray film.
Note that the catheter enters the umbilicus and travels inferiorly before turning superiorly. This “leg loop” is characteristic of an arterial catheter. A UAC follows the aorta and is positioned
slightly to the left of the patient’s vertebral column.
Optimal placement is below the renal arteries and above the aortic bifurcation (L3 to L4) for a low catheter and below the left subclavian artery and above the diaphragm (T7 to T9) for a high
catheter.24 High catheter placement has fewer
complications.3 Fig. 7.9 shows high catheter place-
ment, and Fig. 7.10 shows low catheter placement.
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FIGURE 7.8 High catheter demonstrating “leg loop.”
FIGURE 7.9 Umbilical artery catheter in high position (T8).
FIGURE 7.10 Umbilical artery catheter in low position (L3).
If the catheter is too high, measure on the x-ray film the distance from the tip of the catheter to the desired level, and pull the catheter back the appropriate distance. Some clinicians multiply this length by 0.8 to account for the magnifying effect of the x-ray film. If the catheter is placed too low,
the catheter cannot be advanced but must be removed and replaced because the external por­tion of the original catheter is no longer sterile.
Remove the umbilical cord tie (tape), or maintain the tie very loosely so as not to obstruct blood flow to the umbilical area.
As a teaching model, the umbilical cord can be used for teaching the procedure of both arterial and venous catheterization. Many of the steps can be effectively carried out using a fresh placenta. Special
UACs and monitors are available for continuous PaO2 or oxygen saturation monitoring.
NURSING CARE AND USE OF UMBILICAL ARTERY CATHETERS
Infants can be positioned on their sides or their backs. The abdominal position may be avoided because accidental slipping, kinking, and removal
of the catheter may occur without being imme-
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diately apparent. If the abdominal position is used,
the catheter should be monitored continuously; ensure that pressure alarms are on with parameter settings that would rapidly detect pressure changes.
Care needs to be taken so that the infant is posi­tioned to prevent dislodgement of the catheter.
Diapers are effective for preventing the feet and toes from becoming entangled in the catheter. The dia-
per is folded below the umbilicus. If the infant
is receiving phototherapy and thus is not diapered, leg restraints or positioning aids may be indicated. A mitten or positioning aids are useful to prevent hands and fingers from contacting the catheter. Positioning the catheter away from the extremities lessens the chance of accidental dislodgement. Unless
using a transparent dressing to secure the UAC, a dressing over the umbilicus is unnecessary. Nontransparent dressings inhibit inspection of the umbilicus and evaluation of the catheter. The
IV tubing, connecting tubing, and stopcock should be changed daily. Clots form in the stopcock, so changing it daily prevents the likelihood of thrombus formation. Blood backing into the catheter can be caused by the following:
• Increased intraabdominal pressure, commonly caused by vigorous infant crying
• Disconnection of tubing or a loose connection
• Stopcock turned in wrong direction
• Infusion pump malfunction
• A leak in the filter or tubing or a crack in the stopcock
CHAPTER 7 Physiologic Monitoring
FIGURE 7.11 Stopcock off to IV solution; 1 to 2 mL aspirated into syringe.
173
PROCEDURE FOR OBTAINING AN ARTERIAL BLOOD GAS SAMPLE
Drawing blood samples from an umbilical catheter is a sterile procedure. Samples may be
obtained for blood gas analysis and to obtain labo­ratory specimens. Necessary items include a syringe for initially aspirating IV fluid and blood from the catheter, a heparinized blood gas syringe (if a blood gas sample is to be obtained), a syringe for aspirating laboratory samples (if laboratory samples are to be obtained), and a syringe containing flush solution.
The reinfusion method of obtaining blood sam-
ples is described. This practice involves returning the “discard” blood and, in theory, minimizes patient blood loss.6 Remove the stopcock cap and
place it down so that sterility will be maintained. Attach the empty aspiration syringe to the stopcock. Turn off the stopcock to the IV solution so that the IV solution stops flowing. Aspirate 1 to 2 mL from
FIGURE 7.12 Stopcock in neutral position.
the catheter into the dry aspiration syringe (Fig. 7.11). The IV fluid is prevented from infusing, and aspiration clears the catheter of IV fluid. Turn the stopcock to the neutral position (Fig. 7.12), remove the syringe while keeping the tip sterile, and replace it with the heparinized blood gas syringe or laboratory sample syringe. The neutral position of the stopcock prevents contaminating the sample with IV fluid and prevents blood loss from the infant.
CAUTION: Never allow blood to drip from
an open stopcock. Attach the sample syringe.
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FIGURE 7.13 After blood is aspirated into heparinized 1-mL syringe, stopcock
is placed in neutral position before syringe is removed.
Turn the stopcock off to the IV fluid. Using steady, even pressure, aspirate blood into the laboratory or heparinized blood gas sample syringe. Turn the stopcock to the neutral position, and remove the syringe (Fig. 7.13).
For blood gas samples, remove any air from the syringe (because air bubbles in the sam­ple will cause an artificial rise in PaO2 and a slight fall in PaCO2), cap the end, and chill it to preserve values. Attach the aspiration syringe
containing the aspirated blood and IV fluid. Slightly aspirate to remove any air in the stopcock, and then slowly infuse the aspirated blood and IV fluid. Turn the stopcock to the neutral position, and remove the aspiration syringe. Replace the now-empty aspiration syringe that had aspirated blood and IV fluid in it with the syringe filled with flush solution. Turn the stopcock off to the IV fluid. Slightly aspirate to remove any air in the stopcock, and then slowly infuse the flush solution until the catheter is clear. Return the stopcock to the off position, allowing the IV fluid to now infuse. Replace the stopcock cap. Record the amount of blood removed from the infant and the amount of flush solution used to clear the catheter. Newer methods of gradual, automatic aspiration should be considered if available to prevent abrupt changes in arterial or cerebral pressure.
To ensure the integrity of all connections, the stopcock and other connections must be visible at all times. Do not place the stopcock and other connections under linen, because this would hamper the immediate detection of an accidental disconnection that would cause severe blood loss in the infant. Immediately remove any air in the
tubing or catheter because air is a potential embolus. It is best removed through the stopcock. If the air has passed the stopcock, it can be aspirated back into a syringe easily.
Obtaining an arterial blood gas specimen from a high UAC is better tolerated in premature infants when the entire procedure is done slowly.
Premature and ill term infants have limited cerebral blood flow (CBF) autoregulation. Rapid drops and rises in CBF, especially in the first few days of life, can contribute to neuronal injury and intracranial bleeding.
Rapidly obtaining blood samples from a UAC has detrimental hemodynamic effects on CBF thus, sampling from the UAC should be done slowly.
6
Umbilical Vein Catheter Placement
PROCEDURE
Determine the size and length of the catheter to be inserted. A 5-Fr catheter is normally used in the UVC placement procedure. The ELBW infant may require a 3.5-Fr catheter. To determine the
length of the catheter to be inserted, the distance from the umbilicus to the sternal notch should be measured and multiplied by 0.6. Complete
steps for the placement procedure are found in the Umbilical Artery Catheter Placement section earlier in this chapter. The only difference is that the vein is used instead of the artery. The catheter can be advanced to the desired position easily. The vein is
usually gaping open and does not require dila­tion. The catheter should lie in the inferior vena cava
with the UVC above the diaphragm but below the right atrium of the heart. Catheter position must be ensured. Historically, position confirmation was by
radiologic examination, using the anteroposterior
(AP) and lateral views. Ultrasonography is rapid
and determines correct catheter tip placement
and prevention of complications such as pericardial effusion and tamponade.18 UVCs do not have the
“leg loop” found on the lateral x-ray film of UACs. A UVC follows the inferior vena cava and
is positioned slightly to the right of the patient’s vertebral column. The catheter should be secured in
CHAPTER 7 Physiologic Monitoring
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FIGURE 7.14 Peripherally inserted central catheters and introducers. (Courtesy Becton, Dickinson and Company, Franklin Lakes, NJ.)
175
the same manner as for a UAC. The nursing care
and procedure for drawing blood samples from a UVC are the same as those for a UAC.
Peripherally Inserted Central Catheter Placement
PICCs are silicone or polyurethane products avail­able in a variety of styles including single catheter and needle introducer to a complete insertion kit with instruments, skin disinfectant, and cap, mask, gown, and gloves. Some products provide a stylet and several feature breakaway (splittable) needle introducers. PICCs are available in a variety of sizes for the neonatal population from 20 gauge (3 Fr) to 28 gauge (1.2 Fr).
PICCs typically are inserted for the following
reasons:
• Infants who require IV access that is expect-
ed to be necessary for an extended period
• Infants with limited access
• As a transition from umbilical catheters for
infants weighing less than 1000 g
• As a first-line catheter for infants weighing
1000 to 1500 g
• Infants with gastrointestinal anomalies, necro-
tizing enterocolitis, or gastrointestinal diseases that will require surgical correction
PICCs have long been used to provide highly
concentrated parenteral nutrition and hyperosmolar
medications.
1,43,52
These catheters are relatively easy to insert, affordable, and low maintenance and preclude surgical placement of central venous cath­eters. Due to the extensive dwell time, PICCs
significantly reduce or eliminate the need for repeated painful procedures such as peripheral venipunctures, thus improving patient and par­ent satisfaction.
PROCEDURE
The insertion sites for PICC lines include the bra-
chial cephalic veins, the axilla, the scalp vessels, and the saphenous veins. This sterile procedure can be performed when the infant is on a radiant warmer or in an incubator. A video demonstrating this pro­cedure is available.
28
For an arm or hand insertion, measure the dis­tance from the insertion site to the axilla and then to 1 cm above the nipple line. If the catheter is to be inserted in the scalp, measure from the insertion site to 1 cm above the nipple line, and for a leg insertion, measure from the insertion site to 1 cm above the umbilicus or to the level of the inferior vena cava.
Determine the size and length of the catheter to be inserted—PICC and introducer: 20 to 28 gauge, varying lengths 20- to 65-cm catheter (Fig. 7.14) . Recommendations to trim lengthy catheters vary with manufacturer. A national survey found that 75% of respondents trim catheters. Devices supplied
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by the catheter manufacturer for catheter trimming resulted in a precise cut, whereas scissors produced a ragged cut.
43
A eutectic mixture of lidocaine and prilo­caine (various manufacturers) anesthetic cream or a local anesthetic can be considered before the procedure begins, but these should be used
cautiously because of variable absorption rates and the potential for cardiovascular collapse in neonates (see Chapter 12). Place the infant in the supine position on a radiant warmer bed or in an incu­bator. Ensure continuous temperature monitoring. Skin temperature should remain between 36°C and 37°C (96.8°F and 98.6°F). Provide appropriate oxy­genation and ventilation. Ensure cardiorespiratory and oxygen saturation monitoring.
Restrain the infant’s hands and feet to prevent him or her from contaminating the sterile field and interfering with the placement procedure, or swad­dle the infant, with the site to be used exposed. For hand or arm insertion sites, turning the infant’s head toward the insertion site will cause a slight occlusion of the jugular vein so that, as the catheter is passed into the subclavian vein, the risk for the catheter advancing upward into the jugular is diminished.
52
Don cap and mask. Open the PICC insertion tray; most units now use commercially available disposable trays. PICC insertion tray contents are shown in Fig. 7.15. Open the PICC and introducer (if packaged separately from the PICC insertion tray).
Wash hands and dry with sterile towel before the procedure. Put on a sterile gown and gloves. Connect a lipid-compatible T-connector extension tubing to a syringe of flush solution, and fill the entire apparatus.
Grasp the extremity to be used with sterile gauze so that an occlusive dressing can be applied to the distal part of the extremity, thus allowing manipula­tion of the extremity and precluding contamination of the insertion site by bacteria from distal sites. Cleanse the site with either povidone-iodine or chlorhexidine three times, and allow the site to air­dry. Remove the povidone-iodine with alcohol. For infants weighing less than 1000 g, use sterile water.
Avoid using an excess of skin disinfectant so the infant is not lying in the solution during the procedure. Any residual skin disinfectant should be washed off the infant carefully after the pro­cedure is completed. Place sterile drapes under
the exposed insertion site. Reglove with new sterile gloves. Place the introducer, catheter either with or without stylet (clinician’s choice), syringe, and sterile forceps on the sterile field near the planned insertion site. Insert the catheter into the introducer, being cautious if a stylet is used not to let the stylet extend beyond the tip of the introducer.
Insert the introducer tip at a flat angle to access the vein. The introducer is not advanced into the vein; it is used only as an introducer. At this point, there will probably be no blood return. Once the introducer is in the vein, pick up the catheter with
FIGURE 7.15 Disposable tray used for PICC insertion. (Courtesy Becton, Dickinson and Company, Franklin Lakes, NJ.)
CHAPTER 7 Physiologic Monitoring
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177
the sterile forceps and gently advance the catheter to the premeasured length. Blood should fill the catheter. If the catheter is not advancing, pull the catheter back beyond the point of the introducer and reattempt to cannulate the vein. Once the catheter is advanced to the premeasured length, remove the stylet if used, and attach an empty sterile syringe. If a breakaway cannula is used, gen­tly retract the cannula and slowly peel it apart to prevent premature breakage. Blood should be aspi­rated easily with a syringe. Flush the catheter with
0.5 to 1 mL of flush solution. Secure the catheter using sterile tape or nonfiber adhesive strips at the insertion site. Wrap extra catheter material into a coil above or below the joint to prevent occlusion. Attach the lipid-compatible T-connector extension set, and secure it to the extremity. Dress the inser­tion site, extra catheter loops, and PICC catheter to the T-connector area with a sterile, transparent occlusive dressing. Ensure that the dressing does not completely encircle the extremity causing a tourni­quet effect. Label the dressing with the gauge and length of the catheter, the line type (PICC), and the initials of the insertion person.
Catheter position must be ensured by antero­posterior and lateral x-ray films, ultrasonography, or echocardiography.16 For PICC lines inserted in
the upper extremities, axillae, or scalp vessels, the catheter should lie in the superior vena cava above the right atrium of the heart. Catheters placed in other vessels have a significantly high­er rate of thrombus formation and infection. An
increase in PICC line infections is directly related to increased frequency of venipunctures, especially when no concurrent antibiotics are being used.12 For PICC lines inserted in the lower extrem-
ities, the catheter should lie in the inferior vena cava below the right atrium of the heart.
Catheter placement in the right atrium can lead to complications of dysrhythmias, pleural effusion, and perforation with cardiac tamponade.
NURSING CARE OF PICCS
Infants should be positioned to prevent dis­lodgement or kinking of the catheter. Diapers
are effective for preventing the feet and toes from becoming entangled in the IV tubing. If the infant is receiving phototherapy and thus is not diapered, leg restraints or positioning aids may be indicated. A mitten or positioning aids are useful to prevent hands and fingers from contacting the catheter
52
dressing and IV tubing. Positioning the catheter away from the extremities lessens the chance of accidental dislodgement. The IV tubing should be changed according to the standard of care. Observe
for disconnection of tubing or a loose connec­tion, and ensure an intact and occlusive inser­tion site dressing.
The occlusive dressing should be changed
only when the integrity of the dressing has been lost. A small amount of blood at the inser-
tion site is not a reason to change the occlusive dressing. Maintaining integrity of the occlusive
dressing is instrumental in decreasing the risk for infection.
Changing the current dressing is indicated
when it is no longer occlusive. The occlusive dressing is changed under sterile conditions. The
person performing the dressing change dons a cap, mask, and sterile gloves. Changing the dressing entails removing the transparent film covering the area, clean­ing the insertion site with either povidone-iodine solution or chlorhexidine, allowing this to dry, and then cleaning the site with sterile water to remove the preparation agent from the skin. If the nonfiber adhesive tape or strips are no longer adhesive, they are replaced. Dress the insertion site, extra catheter loops, and PICC catheter to the T-connector area with a sterile, transparent occlusive dressing. Ensure that the dressing does not completely encircle the extremity causing a tourniquet effect. Label the dressing with the gauge and length of the catheter, the line type (PICC), and the initials of the insertion person.
Because of the small gauge, PICCs are not
routinely used for blood sampling. Clotting of
the catheter may rapidly occur. Because the IV tub­ing does not contain a stopcock, significant blood loss and introduction of air into the venous circu­lation can occur.
Peripherally Inserted Midline Catheter
In infants not requiring or unable to receive a cen­tral catheter (vena cava placement) yet still needing IV access for a few days such as for antibiotic thera­py, a peripherally inserted midline catheter (PIMC) can be used. PIMCs are inserted to the midclavicu­lar line. These products are similar to PICCs and are available as a single needle introducer and catheter or as a complete kit.
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Removing Umbilical Artery, Vein, and Peripherally Inserted Central Catheters
When the UAC, UVC, or PICC is no longer needed, it is removed. For UAC catheter removal,
make certain the cord tie is snug. Sterile gauze is needed, and a suture removal kit should be available if the catheter was sutured in place. Turn off the stopcock to the patient and the IV fluid. Withdraw the catheter to 3 cm, and leave it in place for 30 minutes before withdrawing it completely. This procedure works well for infants with respiratory or abdominal issues because it avoids the application of external pressure to the abdomen. Alternatively, withdraw the catheter slowly over several minutes, allowing for the artery to spasm. Pinch the umbil­ical stump with the sterile gauze for 5 minutes until hemostasis is achieved. Observe the umbilicus for active bleeding or oozing. Observe the lower extremities and buttocks for diminished perfusion secondary to a thrombus or embolus.
The procedure is similar for UVCs, with the
exception that the catheter can be slowly with­drawn in one step. Pinch the umbilical stump with
the sterile gauze for 5 minutes until hemostasis is achieved. Observe the umbilicus for active bleeding or oozing. Observe the patient for respiratory dis­tress secondary to a pulmonary embolus.
For PICC removal, clamp the catheter, turn
off the IV fluid infusion, and withdraw the cath­eter slowly and steadily. Apply pressure over the
insertion site with the sterile gauze for 5 minutes until hemostasis is achieved. Observe the insertion site for active bleeding or oozing. Ensure that the entire catheter was removed.
Oxygen Saturation Monitoring by Pulse Oximetry
Oxygen saturation monitoring by pulse oximetry involves placing a small sensor on the infant in such a manner that his or her finger, toe, foot, or wrist comes between the light source and the photoreceptor. The light source emits wave-
lengths of light in the red and infrared spectrums. The difference between the absorption of the light is picked up by the receptor that is placed directly opposite the light source. The calculation of the
ratio of oxyhemoglobin and deoxyhemoglobin is displayed as the percent of oxygen saturation.
Key to accuracy of the monitor is that the light source and the receptor must be directly opposite each other over an area in which a pulse can be detected.
Oxygen saturation monitoring provides con-
tinuous and instantaneous readout of the oxy­gen saturation in the infant. In comparison with
a blood gas analyzer, which calculates the relative oxygen saturation based on established nomograms,
the oxygen saturation monitor measures the actual saturation of the hemoglobin. Calculated
values using standard nomograms do not reflect shifts in the affinity of oxygen for hemoglobin based on changes in the patient’s temperature, pH, PCO2, or 2,3-DPG.
An inorganic phosphate produced in red cells; 2,3-DPG binds to the beta chain of reduced hemo­globin (Hb), lowering Hb’s affinity for O2 and by extension, facilitating O2 release to tissues, causing a “right shift” of the O2 dissociation curve. 2,3-DPG further shifts the curve to the right by lowering the red cells’ pH. When transfused, red cells regain 50% of the 2,3-DPG within 3 to 8 hours and 100% within 24 hours.
The oxygen saturation monitor relies on
adequate perfusion to the site and the ability to detect arterial pulsations; thus, if it is placed
distal to a blood pressure cuff, the reading will be inaccurate while the cuff is inflated. Newer models of pulse oximetry reduce the artifact that results from motion and low perfusion. These newer mod­els also are indifferent to ambient light, whereas older models were affected by light sources such as phototherapy. Newer neonatal probes have built-in external light source protectors. Pigmentation of
the patient’s skin may produce artificially high readings, especially at lower oxygen levels.37 However, a recent comparison of two common­ly used pulse oximeters found no significant dif­ference in systematic bias based on skin pigment (comparing darker to lighter pigmentation in infants with hypoxemia) with either oximeter.
Oxygen saturation is more indicative of the total oxygen content of the blood than is PaO2 and is the most sensitive to hypoxemia when it is on the steep part of the oxygen dissociation curve (see Fig.
7.1). Keeping the SaO2 at 90% to 92% keeps
the infant in a normoxemic state under most conditions. Oxygen saturation monitoring by pulse
oximetry generally is considered reliable and prac­tical for use in infants over a wide range of birth
16