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204 Chapter 11 Anxiety Disorders, Obsessive-Compulsive Disorder, and Somatic Symptom Disorders
Box 11.1 Clinical Perspectives
Loneliness across Childhood and Adolescence
Loneliness is experienced by children, adolescents, and adults across the lifespan. Loneliness is complex and involves aversive emotions such as sadness or frustration coupled with a sense that one is alone or disconnected from others. Varied types of loneliness have been described, including intimate loneliness, the perceived absence of someone with whom one can be oneself and experience mutual connection and support; relational loneliness, the absence of quality friendships or family connections; and collective loneliness, the lack of a valued, shared social identity (Cacioppo et al., 2015). Sources of loneliness include loss, absence, and physical distance. The experience of loneliness peaks in adolescence (Qualter et al.,
2015). Chronic, prolonged loneliness is associated with significant negative impact on well-being, relationships, and health.
For many youth, loneliness is transient. With a strong need to affiliate with others, many children and adolescents are motivated by the aversive experience of loneliness to seek out and sustain social interactions and relationships (Qualter et al., 2015). The qualities of positive relationships change over time. “Children move from simply wanting to be physically close to others to wanting close friendships that are characterized by validation, understanding, self­disclosure, and empathy” (Qualter et al., 2015, p. 252). Peer rejection or isolation may lead to increases in loneliness. In addition to a lack of social partners, believing that one has undesirable social partners or is involved in harmful social relationships contributes to increases in loneliness (Yang et al., 2022).
The environments in which youth are embedded influence loneliness. Cumulative support from parents, peers, and teachers decreases loneliness (Cavanaugh & Buehler, 2016). The potential negative impact of environments was especially evident during
the COVID-19 pandemic, which disrupted the social lives of children and adolescents over several years. Increased rates of loneliness, anxiety, and depression have been repeatedly observed (e.g., Barbieri & Mercado, 2022). For youth with mental health difficulties, the pandemic, with stay-at-home regulations and school closures, amplified existing problems and increased the risk for future problems (Hards et al., 2022; Loades et al., 2020).
Children and adolescents who report being lonely often display negative cycles of isolation, negative social cognitions, and increases in loneliness (Cacioppo et al., 2015). Negative social cognitions include cognitive biases related to negative self-evaluations and negative evaluations of others. These may lead to hypervigilance to social threats and social withdrawal that maintain the negative cycle. For children diagnosed with anxiety disorders, social anxiety and other social information processing factors may exacerbate these negative cycles (Maes et al., 2019). Increasing social opportunities for lonely children is usually not enough to effect positive change (Qualter et al.,
2015). Clinical interventions focused on cognitive bias are designed to increase social motivation and develop social skills, interrupt the negative cycle, and enhance social success (Eccles & Qualter, 2021; Maes et al., 2019).
One last point: Children and adolescents report different reasons for being alone. Not all children and adolescents who spend time alone are lonely. Some choose to be alone, preferring solitary play or solitude. This preference is not necessarily problematic as long as they are able to engage socially when asked or when they choose to be with others. As long as they are not being rejected or rejecting others, for many youth (and adults), time alone can be actively sought, satisfying, and productive (Coplan et al., 2015).
Children and adolescents with OCD often request and receive accommodations from parents and family members. Over 95% of parents and families display some type of accommodation (Kagan et al., 2018; Wu et al., 2019). Accommodations may include verbal reassurance, help and support (such opening doors so child can avoid dirt or germs), participation in anxiety-related behavior (such as checking daily weather reports with a child), and modifying the environment or expectations to reduce anxiety (building in more time in the morning schedule for checking rituals before leaving for school). The more symptoms children or adolescents display, and the greater the symptom severity, the more likely it is that accommodations are made. These accommodations are associated with poor outcomes such as impairment at home and school.
Accommodation is similar in families of youth with anxiety disorders and families of youth with OCD (Lebowitz et al., 2014). Both mothers and fathers display high frequencies of accommodation and accommodate children in similar ways (Monzani et al., 2020). Irritability
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and oppositionality in children and adolescents increase the likelihood of accommodation (Wu et al., 2019).
Siblings, peers, and other adults such as teachers also exhibit accommodation. School accommodations are a complex phenomenon. Some accommodations are essential and support achievement. Accommodations such as extended time for testing for youth with ADHD are both reasonable and legally mandated. Allowing a child or adolescent to practice or present an oral report in front of the teacher rather than in a large class is also reasonable. Exempting youth from on-time arrivals or attendance requirements or substituting written reports for all oral presentations are more problematic. Well-intentioned accommodations by multiple individuals in multiple settings may lead to the maintenance or worsening of OCD or anxiety. “Helpful accommodations should also be a moving target, removed when a youth no longer needs them to be successful. The eventual removal of such accommodations may be indicated for some youths. Others may require additional strategies and supports throughout their life” (Kagan et al., 2018, p. 230).
Etiology 205
Continuity and Course of Somatic Symptom Disorders
Somatic symptom disorders interfere with individual, family, peer, and school functioning (Garralda, 2010; Williams & Zahka, 2017). One of the factors that appears to contribute to ongoing difficulties involves the social consequences of physical symptoms. For example, when children’s pain is associated with positive attention and activity restriction, symptom maintenance is more likely. Once established, a somaticizing pattern is generally chronic and resistant to both psychological and medical treatment (Walker et al., 2012). Individuals with somatic symptom disorders are subject to more frequent and more invasive medical procedures, leading to increased medical costs and potential medical problems. Children and adolescents with these disorders are also at increased risk for other psychopathology such as anxiety disorders and depressive disorders (Walker et al., 2012; Williams & Zahka, 2017).

Etiology

Genes and Heredity
Genetics has a significant impact on the development of both typical and pathological anxiety. Twin and family studies have provided ample evidence that anxious parents are more likely to have anxious children, and that monozygotic twins are more similar to each other in terms of anxiety than dizygotic twins (Iorfino et al., 2021; Lawrence et al.,
2019). As with so many other disorders, data suggest that the genetic influence is the result of many genes, each with a small effect. Genetic influences increase with age, and the influence of shared environments decreases (Vasey et al., 2014). For the most part, the genetic influence appears to involve a general vulnerability rather than a disorder­specific risk (Lawrence et al., 2019). Genetic influences are also significant for OCD (Arnold et al., 2018).
There are many anxiety-related investigations of gene­by-environment-by-time (G 3 E 3 T) and epigenetic processes. For example, some research suggests that genetic effects on generalized anxiety disorder are strongest for girls who experience frequent negative life events (Vasey et al., 2014). Other research emphasizes the impact of complex interactions among genetics, individual differences in stress response patterns, the timing and chronicity of adverse experiences, and perceptions of control and uncontrollability (Smith & Pollak, 2020).
An especially important finding involves the many connections bet ween vulnerabilit y to anxiety-base d disorders and vulnerability to depressive disorders. Over and over, the data suggest a clear overlap between genetic inf luences on the development of anxiety and the development of depression (Hettema et al., 2019; Nivard et al., 2015). Children with both of these internalizing disorders exhibit negative emotion and emotion dysregulation. There are several models that may explain the connections. First, the two types of disorders may share the same underlying etiologies. Second, there may be a temporal association, with anxiety usually preceding depression. Third, anxiety and depression may be distinct psychopathologies, each one increasing the risk that the other will develop. Other explanations involve specific environmental events that, coupled with underlying vulnerability, lead to the expression of either anxiety or depression (Hettema et al., 2019; Zavos et al., 2013).
These varied models of anxiety and depression comorbidity are presented in Figure 11.3 (Cohen et al.,
2014). In both the causal model and the correlated liabilities model, there are independent pathways to both anxiety and depression. Evidence from a longitudinal study supports the diathesis-anxiety model. In this model, children and adolescents diagnosed with anxiety disorders go on to develop depression “if they also tend to ruminate or be self­critical” (Cohen et al., 2014, p. 26).
Figure 11.3 Three models for depression and anxiety in children and adolescents
Causal Model
Anxiety
symptoms
Source: Cohen et al. (2014). Why are anxiety and depressive symptoms comorbid in youth? A multi-wave, longitudinal examination of competing etiological models.
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Depressive
symptoms
Correlated Liabilities Model
Stressors
Cognitive
vulnerability
Depressive
symptoms
Anxiety
symptoms
Diathesis-Anxiety Model
Cognitive
vulnerability
Depressive
symptoms
Anxiety
symptoms
206 Chapter 11 Anxiety Disorders, Obsessive-Compulsive Disorder, and Somatic Symptom Disorders
Physiological Factors
Genetic predispositions to anxiety-based disorders involve multiple mechanisms. Understanding neuroanatomy, neurophysiology, and neurodevelopment are important for explaining both typical and pathological anxiety. Many investigations involve the study of the brain’s right hemisphere, prefrontal cortex, and/or cerebellum. Given its central role in the fear circuit and the processing of threat, the limbic system, particularly the amygdala, is another important research focus. There are extensive connections between cortical regions and the amygdala that develop over time, and amygdala dysfunction such as hyperactivation has been repeatedly documented (Filippi et al., 2022; Zugman et al., 2021).
Stress response systems, including the autonomic nervous system and the hypothalamic-pituitary-adrenal (HPA) axis system, are other contributors to risk (Smith & Pollak,
2020). Research on distributed brain circuitry, or brain connectivity, with evidence of dysfunction across areas may provide meaningful information about neurodevelopmental risk (Zugman et al., 2021).
From the physiological perspective, then, hyperarousal, heightened emotional responsivity, and dysregulation are key contributors to increased risk for anxiety disorders, with early adverse experiences increasing stress sensitivity (Vasey et al., 2014). Other psychophysiological factors that contribute to increased risk include perceptual sensitivity to threat and attention biases toward threat (McLaughlin et al., 2020). G 3 E 3 T research provides important information about interactions between anxiety-related psychophysiological processes and parenting (Buss & Qu, 2018; Morris et al.., 2017; Tan et al., 2020).
For OCD, research is focused on the atypical development and function of the prefrontal-striatal circuits as well as brain connectivity across regions (Bijanki et al., 2021; Kraper et al., 2014). Certain infections may lead to pediatric autoimmune neuropsychiatric disorder associated with Streptococcus (PANDAS), an OCD-like presentation (Gilbert,
2019).
Child Factors
With the emphasis on arousal and dysregulation described in the previous section, it makes sense that temperament is one of the child variables that is associated with anxiety disorders and OCD (Buss, 2011; Stifter & Dollar, 2016). The temperamental trait most associated with anxiety is inhibition. Inhibition involves a mix of wariness, arousal, and emotional and behavioral preferences for any given child (Buss & Qu, 2018; Fox et al., 2005). Many influential investigations by Kagan and his colleagues describe children at risk for later anxiety as both highly inhibited and highly reactive (e.g., Kagan & Fox, 2006).
Inhibition influences anxiety problems in a number of ways. In the diathesis-stress model, inhibition is a risk factor that leads to wariness or fear in the presence of
environmental stressors. Inhibition or dysregulation may also co-occur with other factors that lead to anxiety (such as parental overprotection). Temperament characteristics and anxiety may interact with one another in a negative cycle, with heightened negative affectivity leading to increased anxiety and increased anxiety further increasing already high levels of inhibition, negative emotion, and dysregulation. Temperament characteristics and anxiety may also share the same underlying dimensions. These varied processes are not mutually exclusive, and likely all of them contribute to the multiple pathways to anxiety disorders (Buss & Qu, 2018; Fillipi et al., 2022).
Emotion regulation (monitoring, moderating, and enduring emotion) (ER) and emotion dysregulation also contribute to the etiology of anxiety disorders (Beauchaine & Cicchetti, 2019; Fox, 2018). Individual differences in ER and dysregulation appear early and are stable over time (McQuillan et al., 2018). As described previously, ER strategies include acceptance of emotion experience, problem solving, cognitive reappraisal, avoidance, suppression, and rumination. The most helpful ER strategies (acceptance, problem solving, reappraisal) are displayed less often in youth diagnosed with anxiety. More problematic strategies (avoidance, suppression, rumination) are displayed more often (Schäfer et al., 2017).
The strategy of acceptance involves some degree of distress tolerance (the perceived or actual ability to tolerate negative emotion). Youth with low levels of distress tolerance are less likely to view acceptance of the negative emotion experience as a potential ER or coping strategy. Indeed, distress intolerance is a transdiagnostic risk factor that predicts increases in anxiety, depression, and avoidance across development (Zvolensky et al.,
2010).
Anxiety sensitivity may further interfere with effective emotion and behavioral regulation (Knapp et al., 2016; Weems et al., 2010). To the extent that children and adolescents are predisposed to immediately focus on and overreact to uncomfortable body sensations, high levels of anxiety sensitivity may be conceptualized as a diathesis. Coupling this diathesis with significant or multiple stressors may explain the development of panic disorder or somatic symptom disorder in some youth.
Because effective ER develops over time and includes repeated practice with varied emotion experiences and varied strategies, children and adolescents who do not practice with at least some of the helpful strategies are unlikely to develop skilled ER. Emotion suppression (concealing emotion experience) is a strategy with emotional and social costs, including an increase in anxiety symptoms (Gross & Cassidy, 2019). Individual differences in emotion suppression are influenced by neurodevelopment, family processes, and cultural processes. Peers also provide signals about appropriate or acceptable emotion expressions (Gross & Cassidy,
2019).
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Etiology 207
The influence of cognitive variables on the development of anxiety disorders is also very salient. Cognitive and attentional biases to perceive and attend more closely to threatening stimuli, cognitive appraisals of ambiguous situations as negative and threatening, specific cognitive distortions related to the self (such as low self-efficacy), and rumination all contribute to increased risk for anxiety disorders (Schäfer et al., 2017; Songco et al., 2020; Vasey et al., 2014). With respect to specific patterns of negative cognitions and impaired decision making, combinations of hypervigilance for threat and self-doubt lead to “a hesitant, risk-averse, and self-deprecating decision-making style” (Sonuga-Barke et al., 2016, p. 335). Broad impairments in executive functioning may be especially important to consider in children and adolescents with OCD (Snyder et al., 2015).
Social information processing factors such as cognitive biases and negative interpretations are associated with heightened anxiety and avoidance of social interactions and social situations (Nikolić, 2020). Difficulties with social cognition, such as that observed with theory-of-mind difficulties in youth with autism, are also associated with social anxiety disorder (Pearcey et al., 2021).
Early experiences with control and lack of control may contribute to a lack of security and a cognitive predisposition to assume that one cannot control events or outcomes. This predisposition underlies a sense of helplessness and increases a child’s general vulnerability (Weems & Silverman, 2006). Perceptions of controllability/uncontrollability influence coping strategies and the development of internalizing disorders (Compas et al., 2017). Adolescents’ use of secondary control coping (acceptance, cognitive reappraisal) is associated with fewer internalizing symptoms (Anderson et al., 2021). Intolerance of uncertainty is also linked to high levels of anxiety and worry (Osmanagaoglu et al., 2018).
A cognitive model of OCD describes several factors related to dysfunctional beliefs and maladaptive interpretations of intrusive thoughts (Cervin et al., 2022). These include: inflated responsibility beliefs and heightened estimates of threat, thinking one caused or influenced an event that is associated with harm; perfectionism and intolerance of uncertainty associated with checking, rituals, reassurance seeking; overimportance and control of thoughts related to thought-action fusion, the belief that thoughts and actions are equivalent (that having a distressing thought is the same as engaging in distressing behavior); and dysfunctional metacognitive beliefs or meta­worry, which is the belief that worrying may help as well as the belief that worrying makes things worse (Cervin et al.,
2022). Various patterns of these factors are observed in OCD as well as in some anxiety disorders.
Behavioral models of risk and psychopathology emphasize that children’s learning is at the root of anxiety. Rachman’s (1977) theory of fear acquisition presented three pathways to disorder: direct conditioning, modeling, and/or instruction or information. There are data to support both direct and indirect pathways (Rapee et al., 2009; Vasey et al., 2014).
Avoidance is frequently discussed in connection with behavioral models. Avoidant behavior is associated with decreases in distress. The short-term benefits associated with decreased distress must be considered along with the long-term consequences of maintaining and strengthening escape and avoidant behavior related to fear and anxiety. If avoidance is coupled with problem solving or when it allows a child some space to settle down before re-engaging the feared stimulus or situation, however, it may be a flexibly­used strategy. Maladaptation occurs when avoidance is inflexible or unproductive (Hofmann & Hay, 2018).
Insecure attachments lead to both short- and long-term outcomes involving anxiety disorders (Lewis-Morrarty et al., 2015; Vasey et al., 2014). As summarized in Chapter 5, the heightened risk involves not only more frequent experiences of anxiety, but also difficulties engendered by the caregiver’s problematic and often ineffective attempts to manage the child’s wariness or distress. Although children with histories of resistant attachment, avoidant attachment, and disorganized attachment are all at increased risk, children with disorganized attachments appear to be at greatest risk. Clinical disorders are more likely when these insecure attachment-related risks are combined with other risk factors (Kerns & Brumariu, 2014).
Parent Factors
The family context in which children’s genetic inheritance and psychological makeup is embedded is critical to the development of anxiety-based disorders. The transactional approach to psychopathology, discussed in many other chapters, emphasizes the connections among child variables, parent and relationship variables, and larger ethnic and cultural variables. Parental psychopathology, including anxiety disorders and OCD (as noted in the previous section on genetics) is associated with increased vulnerability.
Multiple aspects of parenting have been identified as risk factors including overcontrol, overprotection, and overinvolvement (Creswell et al., 2020). Temperament interacts with parental behaviors, with inhibited children more likely to elicit overcontrol and overprotection (Bates & McQuillan, 2019). Dysregulation also plays a role. The more emotionally negative and dysregulated the child, the more important positive parenting is (Morris et al., 2017). Developmental status is another factor to consider. As young children shift from co-regulation of difficult emotions to a mix of co-regulation and independent regulation, how parents respond to children’s distress is important (Compas et al., 2017; Gross & Cassidy, 2019). Overall, parenting behaviors that are problematic are those that decrease the likelihood that children or adolescents will engage with anxiety-eliciting stimuli and situations and develop effective ER and coping strategies.
Parent fears and worries, modeling of avoidant behavior, and accommodation of anxiety and avoidance are all related to both the development and the maintenance of anxiety
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208 Chapter 11 Anxiety Disorders, Obsessive-Compulsive Disorder, and Somatic Symptom Disorders
disorders and OCD (Doom et al., 2021; Vasey et al., 2014). Parents contribute to several anxiety trajectories. Parents may socialize their children to view the world as dangerous and children themselves as unable to cope. Anxious parents may model anxiety and avoidance. Parents may respond to child anxiety in ways that maintain or increase anxiety and avoidance. These parenting factors may be more salient for temperamentally sensitive or hypervigilant children (Creswell et al., 2020; Vasey et al., 2014).
Individual and family dynamics are embedded into particular cultural contexts, which help explain the presentation, course, and treatment of anxiety disorders (Doom et al., 2021). Even in communities and cultures where parental control and involvement is more frequent and widely accepted (such as in Latino families), control and involvement are predictive of youth anxiety (Varela & Hensley-Maloney, 2009; Varela et al., 2013). In addition, culture-specific inf luences have also been observed. Strict adherence to cultural values emphasizing group harmony in Latino families, for example, combined with low levels of emotion awareness in youth, increases the risk for anxiety (Varela et al., 2019).
Environmental Factors
Adverse life events experienced by children also influence risk and vulnerability. Loss of parents, parental divorce, and maltreatment all increase the risk for the development of anxiety disorders (Lawrence et al., 2019; Vasey et al.,
2014). Chronic stressors such as socioeconomic adversity, discrimination, family problems, and friendship problems have also been identified as contributing to the development and stability of anxiety pathways (Doom et al., 2021; Kertz et al., 2019). Reviews of investigations of environmental risk factors for the etiology of OCD reveal few, if any, environmental contributions (Brander et al., 2016).
Two examples of the impact of environmental stressors on anxiety symptoms and trajectories involve exposure to COVID-19 pandemic stress. In the first study, adolescents and young adults displayed increased anxiety symptoms related to the psychosocial effects of the pandemic (Kujuwa et al., 2020). In the second study, a developmental pathway was described, from behavioral inhibition in preschoolers to dysregulated worry in adolescents to elevated and dysregulated anxiety in young adults during the pandemic (Zeytinoglu et al., 2021).

Assessment and Diagnosis

There are two main tasks of assessment: (1) to determine whether children’s anxiety reflects typical or atypical adjustment, and (2) to discriminate among anxiety disorders. Comprehensive assessment of anxiety disorders, including interviews, self-reports, rating scales, physiological assessments, and observations, is vital to evidence-based clinical practice (Creswell et al., 2020; Hunsley & Mash,
2020). Anxiety questionnaires, such as t he Rev ised Children’s Manifest Anxiety Scale (RCMAS) and the Screen for Child
Anxiety Related Disorders (SCARED), provide effective general screening for anxiety disorders. Other measures, such as the Multidimensional Anxiety Scale for Children (MASC), help differentiate among specific anxiety disorders. In addition, there are questionnaires that help clinicians distinguish between internalizing disorders, including anxiety and mood disorders (Fleischer et al., 2020).
For younger children, narrative stories may be used to elicit anxiety themes (Warren et al., 2000). Parent and teacher forms of anxiety rating scales are also used frequently (Reardon et al., 2018). Parent attitudes and expectancies can also be assessed (Eisen et al., 2004). A developmental systems framework focused on child-family transactions may be useful as well (Hunsley & Mash, 2020).
Even with abundant data, interpretation is often difficult. That’s because agreement between children’s reports and parents’ reports of anxiety symptoms and avoidant behavior is usually poor (Hoffman & Chu, 2015; Meiser-Stedman et al., 2007). Discrepancies among parent, teacher, and clinician ratings of adolescent disorders have also been reported, and these discrepancies are associated with poor outcomes (Hoffman & Chu, 2015). Transgender and gender-diverse youth, for example, report more severe anxiety compared to their parents (in contrast to similar ratings for depression (McGuire et al., 2021). Reasons for the lack of agreement include children’s ability (or inability) to describe their anxiety, children’s willingness (or lack of willingness) to disclose their anxiety, parental awareness (or lack of awareness), and parental distress. These reasons underscore the need to gather data from both children and parents and emphasize the need to increase parent recognition of youth mental health difficulties (McGuire et al., 2021; Youngstrom et al., 2003, 2004).
When an assessment for anxiety disorders involves youth with other disorders such as those with autism spectrum disorder, standardized instruments, especially self-report measures, may provide less useful information. Psychologists may rely more on observational methods along with parent and teacher questionnaires for an accurate diagnosis (Kalvin et al., 2020; Perihan et al., 2021).
Clinicians also need to take into account the cultural backgrounds of children and their families, especially when making decisions about internalizing disorders (Garralda & Raynaud, 2008; Hunt, 2020). Finally, as with every disorder, it is important to take into account a child’s strengths and resources. These positive characteristics remind the clinician (as well as parents and teachers) that children are more than their disorders. Further, these positive characteristics may be incorporated into a treatment plan that maximizes therapeutic engagement.
Assessment and diagnosis of obsessive-compulsive disorder, as with anxiety disorders, must take into account typical development, such as the routines and rituals of young school-aged children (Kraper et al., 2014). Structured interviews and child and parent reports are all part of a comprehensive clinical intake. Assessment of OCD severity
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Intervention 209
and impairment must be addressed. The Yale-Brown Obsessive-Compulsive Scales (Y-BOCS) is a widely-used questionnaire designed to rate symptom type and severity in youth with OCD. Comorbid and differential diagnoses are likely to focus on tic disorders, anxiety disorders, and autism spectrum disorder (Lewin & Piacentini, 2010).
Perhaps more than any other physical or psychiatric diagnosis, somatic symptom disorders require an integrated approach involving combined medical and psychological perspectives. The critical starting point is to rule out known physical causes. In pediatric settings, high rates of medically unexplained symptoms should prompt physicians to explore internalizing psychopathologies (Agarwal et al., 2019). This can then be followed by a consideration of how well the symptoms meet the criteria for a somatic symptom disorder, although it is again important to understand symptoms in the context of culture.
Because the child, and often the family as well, have a considerable psychological investment in the physical symptoms, both are likely to respond with frustration and even distrust when confronted by an inadequate medical explanation. Also, these children and adolescents are, by definition, resistant to an attribution that focuses on emotional functioning. Consequently, they are unlikely to accept a referral for psychological intervention. At least for the more severe somatization cases, then, collaboration between the psychologist and pediatrician is crucial.

Intervention

As with all psychopathologies, the prevention or reduction of anxiety disorders is the goal of mental health professionals. A number of prevention programs have demonstrated success, and new ideas related to prevention are also promising (Palitz et al., 2019; Vasey et al., 2014). These programs have been implemented in preschools and elementary schools. One relatively low-cost prevention program involves identifying highly inhibited preschoolers in a day care setting and providing a brief, six-session parenting intervention designed to reduce anxiety disorders (Mihalopoulos et al.,
2015). When prevention is not possible, early interventions become very important, not only for the immediate relief of symptoms but also to reduce the risk of later disorders. Early interventions for children with multiple phobias, for example, may decrease overall risk for later internalizing disorders and poor outcomes (de Vries et al., 2019).
The therapeutic alliance is an essential component of all psychological interventions. It is especially critical in psychological treatments for anxiety disorders, obsessive­compulsive disorder, and somatic symptom disorder. Children, adolescents, and parents are participating in interventions that require, at times, tolerance of increased distress and anxiety before improvement occurs. A strong therapeutic alliance ensures that children and adolescents understand the deep concern the therapist has for their well-being and supports ongoing engagement and effort across treatment sessions.
Pharmacological Treatment
Many effective treatments combine psychological and pharmacological techniques, with anxiety medications prescribed most frequently for children and adolescents with anxiety disorders and obsessive-compulsive disorder (Freeman et al., 2018; Norris & Kendall, 2021; Palitz et al., 2019). Although research continues, these combined therapies seem especially appropriate for older children and those with more severe symptoms as well as for complex cases that involve comorbidity. In the future, it is likely that the recent growth in the pharmacological treatment of anxiety disorders in young people will become more refined due to the ongoing clinical trials of medications that include children and adolescents.
Psychological Treatments
Given the nature of internalizing disorders, many children and adolescents become the focus of intervention efforts only after an anxiety disorder is firmly rooted. Many others who struggle remain undiscovered and untreated. Effective treatments for the wide range of anxiety disorders are available (Baker et al., 2021; Comer et al., 2019; Zhou et al., 2019). The treatment of choice is cognitive-behavioral therapy. Cognitive-behavioral therapy (CBT) is based, in large part, on the work of Phillip Kendall and his colleagues (e.g., Albano & Kendall, 2002; Kendall, 2012) and is associated with both immediate and long-term improvements. Problematic beliefs, such as being unable to cope with fear-eliciting threats or situations, are a key target of CBT interventions. Behaviors associated with ongoing or worsening anxiety such as avoidance are also intervention targets. New learning experiences related to what happens in anxiety-eliciting situations provide alternatives to maladaptive patterns. Relaxation training is often an important component of CBT.
The six main components of CBT are summarized in Table
11.5 (Velting et al., 2004). They are: (1) psychoeducation, (2) somatic management, (3) cognitive restructuring, (4) problem solving, (5) exposure, and (6) relapse prevention. Psychoeducation involves providing children and their families with information about typical anxiety and the emergence and maintenance of pathological anxiety as well as about the theoretical and practical aspects of CBT. Somatic management involves targeting the distressing physiological symptoms and is usually focused on relaxation and breathing techniques. In addition, children and adolescents learn how to predict and tolerate the anxiety that accompanies challenging and stressful events. Cognitive restructuring has to do with the identification and modification of negative thoughts that elicit and prolong anxiety. Thinking about emotions and emotional biases also may be important and is the focus of treatment efforts in some instances. Problem solving is a step-by-step, active, behaviorally oriented approach for coping. Exposure to the stimuli and situations that are associated with anxiety is systematic and controlled, with in vivo (real-life) practice
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210 Chapter 11 Anxiety Disorders, Obsessive-Compulsive Disorder, and Somatic Symptom Disorders
Table 11.5 Main Components of Cognitive-Behavioral Therapy
Components Focus/Goals Associated Techniques
Psychoeducation
Somatic management
Cognitive restructuring
Problem solving
Exposure
Provide corrective information about the nature of anxiety and feared stimuli
Target autonomic arousal and related physiological symptoms, focus attention away from anxiety-arousing physical sensations, break the association between physiological arousal and anxiety
Identify maladaptive (i.e., unhelpful) thoughts, beliefs, and images, and teach realistic, coping-focused thinking
Develop a variety of active methods for coping with specific problem situations and a system for testing the potential solutions
Graduated, systematic, and controlled exposure to feared situations to provide experience at using anxiety management skills and consolidation of psychoeducation material
Didactic instruction, self-monitoring (diaries), and assigned reading
Breathing retraining (deep and slow diaphragmatic breathing), relaxation training (progressive muscle/applied relaxation), meditation, and exercise
Monitoring of thought processes (diaries), identification of automatic thoughts, teaching rational disputation of automatic thoughts, use of behavioral experiments to gather evidence to refute automatic thoughts, and use age-appropriate methods for younger children
Identify the specific problem, generate multiple alternative actions for improving the situation, explore costs and benefits of each potential solution, determine and implement the preferred or most feasible alternative, and evaluate outcomes
Behavioral exposure to feared situations, interoceptive exposure to feared bodily sensations (such as in panic disorder), exposure should be direct (in vivo), but may begin with imaginal or symbolic exposure (e.g., use of photos of the feared object instead of actual stimulus)
Relapse prevention
Source: Velting et al. (2004). Update on and advances in assessment and cognitive-behavioral treatment of anxiety disorders in children and adolescents.
preferred. Relapse prevention involves laying the groundwork for the maintenance and generalization of improvements.
Both individual and group formats do very well, with approximately 60% of youth displaying positive outcomes. Many children and adolescents display full recoveries (Creswell et al., 2020; McKinnon et al., 2018; Warwick et al., 2017). Sociodemographic variables such as age, sex/ gender, and race/ethnicity do not appear to influence treatment outcomes. Research on comorbidity is mixed, with some findings related to less positive treatment response for youth with multiple diagnoses, while other findings reveal similar treatment response (Norris & Kendall, 2021). CBT is effective for youth with comorbid autism spectrum disorder and anxiety disorder (Warwick
Focus on consolidating anxiety management skills and generalizing treatment gains over time, and decrease reliance on therapist and others (e.g., parents) for managing anxiety
et al., 2017; Wood et al., 2020). In addition to the anxiety disorders, empirical support has also been found for psychological interventions such as CBT for somatic symptom disorders (Bonvanie et al., 2017; Williams & Zahka, 2017). Computer-based CBT is also effective for many youth (Christ et al., 2020).
Cognitive control training (CCT) is focused on youths’
abilities to increase control over mental processes (shifting attention and focus, inhibition of automatic responses). The goals of CCT include direction of attention away from emotionally-upsetting stimuli and better management of cognition-emotion interactions. A review of CCT treatment studies suggests that it is an effective anxiety-reduction intervention.
Fading of sessions (from weekly to biweekly), role reversal (child acts as therapist for a session), videotape commercial of therapy program, and planned booster sessions
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Intervention 211
Internet-based treatments, with various educational and experiential components presented in interactive formats, have also been effective and are well received by both children and parents (Lenhard et al., 2017; Nordh et al.,
2021). Because anxiety treatments are in high demand, stepped-care treatment approaches may be used. All youth needing treatment at a clinic, for example, may begin with a computer-administered intervention. After completion, those requiring more intensive help would be offered the opportunity to step-up to individual CBT. This type of approach is cost effective and increases the number of children and adolescents who receive treatment (Yeguez et al., 2020). Mental health monitoring apps for anxiety also provide opportunities for increased engagement in treatment for some youth. The ethical use of such apps requires careful consideration (Williams & Pykett, 2022).
For children and adolescents whose anxiety has interfered with the development of age-appropriate and rewarding peer relationships, social skills interventions may be especially important. School-based group interventions provide opportunities for achieving anxiety- and peer­related improvements (Haugland et al., 2020; Silverman et al., 2019). Summer programs with camp-based activities are another option (Santucci et al., 2015).
For children and adolescents with OCD, exposure­based CBT—exposure and response prevention (ERP) treatments—are the standard evidence-based interventions (Freeman et al., 2018; Metcalfe et al., 2022). ERP includes gradual exposure to situations designed to provoke OCD symptoms in a safe environment and under supportive conditions coupled with the prevention of problematic behaviors such as avoidance or rituals. The goal of ERP is not to totally remove anxiety-eliciting situations, negative thoughts, and compulsions but to develop greater distress tolerance and coping skills in the face of them.
Acceptance and commitment therapy (ACT) emphasizes mindfulness and focuses on the present moment and acceptance of thoughts and feelings without judgment. ACT has increasingly been incorporated into the treatment of anxiety disorders as well as OCD (Twohig et al., 2018).
Given the salient role of the parents in etiology and maintenance of anxiety disorders, OCD, and somatic symptom disorders, it makes sense to work within a treatment framework that incorporates family factors and includes parents in treatment design and implementation (de Barros et al., 2020; Cardy et al., 2020; Hulgaard et al.,
2019). It is also important to consider more general and bidirectional cultural factors (Kendall, 2012). In particular, treatments for anxiety disorders and OCD need to address parent and family accommodation (Kagan et al., 2018). Trajectories of decreasing accommodation predict better outcomes (O’Connor et al., 2021).
Designing various treatments for several of the children described earlier in the chapter provides examples of these psychological treatments. To help Lakshmi with her separation anxiety disorder and school refusal, it was
important to first clarify for her parents and family that it was not school that was upsetting Lakshmi. Rather, anxiety about separating from her mother was interfering with her entry into first grade. Consequently, intervention efforts were aimed at restoring Lakshmi’s confidence in her relationship with her mother as well as her own self­confidence. To help with the transition to a calmer start to the school day, a picture of her mother was taped to the inside of her desk as a reminder that her mother was fine and would be waiting for her at home at the end of the day. For several days, Lakshmi was also allowed to call her mother after lunch if she wished. By the end of four weeks of these efforts, Lakshmi was again looking forward to her school day and separated from her mother easily in the morning.
For Jack’s weather phobia, any of four classic behavioral treatments for fears (or combinations of these treatments) might be used, including modeling, systematic desensitization, reinforced exposure, and self-talk (Weisz,
2004), with attention paid to the individual response pattern and developmental status. Modeling treatments are based on the impact of observational learning. With this approach, Jack might participate in symbolic modeling (using videos of children displaying nonfearful behavior during bad weather), live modeling (using in-person observation of nonfearful children playing outside in the rain), or participant modeling (pairing Jack with a nonfearful child). Depending on the child, modeling treatments may achieve good outcomes quite quickly. Systematic desensitization involves teaching an anxious child how to relax and how to maintain relaxation when exposed to the feared stimulus. Exposure is done gradually (i.e., systematically, from watching clouds and rain showers on videos, to watching actual storm clouds and rain from inside the home, to going on drives with a parent during a rainstorm), building on the child’s successes over time. Exposure involves rewarding a child for desired behavior. In Jack’s case, he might receive tokens for more functional weather-related behaviors. Self-
talk is a cognitive technique focused on providing positive
self-statements such as “I am brave,” to enhance appropriate behaviors. All these treatment approaches depend on establishing a trusting relationship with a therapist because children need to believe (and feel deep down) that this adult will keep them safe.
Charlotte, the girl diagnosed with generalized anxiety disorder, needed to spend several sessions becoming accustomed to, and comfor table with, the therapeutic setti ng, the therapist, and the therapeutic relationship. Charlotte and her parents discussed the age-related expectations and tasks that were important to her and the ways that it would be advantageous (and even fun) to meet them. She spent many of the sessions engaged in role playing and practicing self-talk strategies that would help her manage her base levels of anxiety and her specific anxiety symptoms.
Asher, diagnosed with autism spectrum disorder and generalized anxiety disorder, received more specialized support in school settings. The school psychologist and
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212 Chapter 11 Anxiety Disorders, Obsessive-Compulsive Disorder, and Somatic Symptom Disorders
Asher’s teachers more effectively identified anxiety triggers and early signs of Asher’s distress. A new behavioral plan was developed to clearly signal upcoming transitions and reward Asher for verbalizing thoughts and feelings. Asher’s teachers and parents collaborated to help Asher develop new ways of coping with increases in anxiety. The school psychologist also made a referral to a community therapist experienced in working with ASD youth and their families. This therapist worked with Asher and his parents using a CBT approach adapted for higher functioning autistic youth that focused on the identification and differentiation of emotions combined with anxiety management techniques such as deep breathing and relaxation.
Daniel, diagnosed with OCD, received an intervention that first involved education for him and his parents about the disorder. During these discussions, Daniel’s father also revealed that he also had experienced a variety of significant anxiety symptoms, including some sub-clinical obsessive­compulsive behaviors. A cognitive-behavioral treatment plan was developed, and a referral for a medication consultation was made. Cognitive techniques were used to identify patterns of thoughts and behaviors that had become maladaptive, and new, more effective strategies for dealing with anxiety were developed. Behavioral plans to limit compulsive behaviors were also created, including techniques that exposed Daniel to triggering stimuli while
preventing the compulsive response. In this way, he became desensitized to anxiety-provoking stimuli and no longer felt the urgent need to engage in the compulsive behaviors.
After several meetings with Isabella and her parents, the hospital team working with her diagnosed a somatoform pain disorder. In discussing this with Isabella and her parents, it was emphasized that no one thought that she was faking. Rather, the facts that Isabella very much wanted to do well in high school and also please her parents were noted, and the suggestion was made that although Isabella was not feeling directly anxious about this, the pressure to perform had begun to interfere with her ability to manage her daily demands. As part of this suggestion, the therapist mentioned that there were many ways in which bodies and minds work together, in both positive and negative ways. A plan was developed with input from the family, physician, and psychologist in which medical monitoring would be combined with help from the psychologist a s Isabella returned to school. It was emphasized that although they would continue to investigate physiological factors, the most truly dangerous possibilities had already been ruled out, and it was medically safe for Isabella to return to school. Gradually, the psychologist helping her became more involved in coaching her to develop more adaptive and effective ways of managing stress in her life. Mind–body pain management strategies were an important component of ongoing treatment.
Key Terms
Distress tolerance (193) Fears (194) Worries (194) Anxiety disorders (195) Anxiety sensitivity (195) Separation anxiety disorder (SAD) (195) Phobic disorders (197) Specific phobias (197) Social anxiety disorder (197) Agoraphobia (197) Generalized anxiety disorder (GAD) (199) Panic disorder (200)
Chapter Summary
Fears and worries are typical and expected parts of childhood and adolescence. When they consistently interfere with healthy development, an anxiety disorder may be present.
Emotional experiences, including emotion regulation (ER), follow a developmental course that must be considered when determining whether typical anxiety crosses over to pathological anxiety.
Obsessive-compulsive disorder (OCD) (201) Obsessions (201) Compulsions (201) Somatization (202) Somatic symptom disorders (202) Conversion disorder (functional neurological symptom
disorder) (202)
Accommodation (203) Cognitive-behavioral therapy (CBT) (209) Cognitive control training (CCT) (210) Modeling (211) Systematic desensitization (211) Exposure (211) Self-talk (211)
Anxiety disorders represent the maladaptive experience of
anxiety in terms of intensity, duration, and pervasiveness.
They are also characterized by inhibition and withdrawal,
exaggerated and unrealistic fears and worries, and
overcontrol. Avoidant behavior is frequently part of the
clinical presentation.
Anxiety disorders are among the most frequently
diagnosed disorders in children, adolescents, and adults.
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Intervention 213
Some of these disorders, such as generalized anxiety disorder, represent an anxious reaction to a wide array of stimuli, while others, such as separation anxiety disorder and specific phobias, are rooted in more specific anxiety­producing situations.
Obsessive-compulsive disorder involves obsessions (persistent, intrusive, and negative thoughts or images) coupled with compulsions (impulses or ritualized behaviors). Clinical presentations are varied.
Somatic symptom disorders involve the experience of physical symptoms that appear related to the moderation of emotions, especially anxiety. Anxiety sensitivity is often exhibited.
Genetic and other physiological risk factors are clearly linked to the development of anxiety disorders. Research suggests that anxiety and mood disorders result from closely related risk factors.
Child factors related to increased risk include behavioral inhibition, emotion dysregulation, and varied cognitive factors.
Parenting behaviors that may potentially contribute to the development of anxiety disorders include an anxious style of parenting, such as overinvolvement and overprotection, as well as the modeling of anxious and avoidant behavior. Accommodation is associated with the maintenance of symptoms and worse outcomes.
Comprehensive assessments, i ncludi ng clinical i nter views, self-report measures, and clinical observations, are used to differentiate typical from pathological levels of anxiety and to discriminate among anxiety disorders.
A variety of psychological interventions (cognitive­behavioral therapy in particular), often in combination with pharmacological approaches, have proven effective in the treatment of anxiety disorders.
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