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Файл:Ординатура / Хирургия / Библиотека им академика М.И. Перельмана / Книга_1056_Библиотеки_им_академика_М_И_Перельмана.pdf
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- •Preface
- •Contents
- •About the Editors
- •Contributors
- •3 Host Factors: Age, Gender, Lifestyle
- •4 IBD and Other Etiologically Relevant Comorbid Conditions
- •5 Anatomical Presentation and Rectovaginal Fistula
- •6 Anal Fistula Development: Microbiological Factors
- •7 Recurrence and Cancer Risk
- •8 Conclusion
- •References
- •1 Epidemiology of Anal Fistula and Abscess
- •1 Introduction
- •2 Incidence and Prevalence
- •2.1 Europe
- •2.2 USA and Canada
- •2 Anorectal Anatomy Related to Anal Fistula and Abscess
- •1 Introduction
- •2 Mucosal Layer and Submucosal Space
- •3 Internal Anal Sphincter
- •4 Intersphincteric Space and Conjoint Longitudinal Muscle
- •5 External Anal Sphincter
- •6 Pelvic Floor
- •7 Extra-anal Spaces/Ischioanal Fossae
- •8 Anal Glands
- •10 Conclusion
- •11 Cross-References
- •References
- •3 Anorectal Physiology Related to Anal Fistula and Abscess
- •1 Principal Aspects of Anorectal Physiology
- •1.1 Secretory Function of the Anorectum and the Cryptoglandular Hypothesis
- •1.2 Histology and Cellular Physiology of the Anorectum and Fistula
- •1.3 Microbiology and Fistula
- •1.4 Host Factors Relevant to Abscess and Fistula
- •1.5 Anal Continence
- •1.5.1 The Rectum
- •1.5.2 The Musculature of the Pelvic Floor and Sphincter Complex
- •1.6 Defecation
- •1.7 Anorectal Physiology Testing in the Context of Fistula
- •1.7.2 Perioperative Anorectal Physiology Testing
- •2 Conclusion
- •References
- •4 Unconventional Insights in the Pathogenesis and Etiology of Fistulas in the Perianal Region
- •1 Introduction
- •1.1 Etiology
- •1.2 Risk Factors for Development of Perianal Fistula
- •1.3 Risk Factors due to the Type of Perianal Fistula
- •1.4 Treatment-Related Risk Factors for Failure
- •1.5 Preliminary Conclusions
- •2.1 Anatomy of the Anal Canal
- •2.2 Histology of the Anal Canal
- •2.3 Histopathologic Concepts of Perianal Fistulas
- •3.1 Old Stories, New Histopathological Concepts?
- •3.2 Old Stories, New Clinical Concepts?
- •3.2.1 Basic Concepts
- •3.3 Based on Previous Medical History
- •3.4 Aspect and Localization of the Fistula Opening
- •3.5 Phenotype 1
- •3.6 Phenotype 2
- •3.7 Phenotype 3
- •3.8 Phenotype 4
- •3.9 Phenotype 5
- •4 Discussion and Conclusions
- •5 Cross-References
- •References
- •5 From Abscess to Fistula
- •1 Anorectal Abscess
- •References
- •6 Classification of Anal Fistula and Abscess
- •1 Introduction
- •2 Purpose and Attributes of a Classification
- •3 Overview of Anal Fistula Classifications
- •4 Anal Fistula Classifications
- •4.1 Parks Classification
- •4.1.1 Strong Points
- •4.1.2 Weak Points
- •5.1 Strong Points
- •5.2 Weak Points
- •6 Garg Classification
- •6.6 Strong Points
- •6.7 Weak Points
- •7 Status of Extrasphincteric Fistulas
- •8 Evaluation of Existing Classifications on Long-Term Data
- •9 Conclusions
- •References
- •7 Clinical Assessment of Anal Cryptoglandular Abscess and Fistula
- •1 Introduction
- •2 Types of Clinical Evaluation
- •3 Diagnosis
- •4 Topographic Evaluation
- •4.1 The Cryptic Endoanal Primary Opening
- •4.2 The Secondary Opening or Openings
- •4.3 The Main Tract of the Fistula
- •4.4 Possible Purulent Collections
- •1.1 Physical Examination of the Anus and Rectum: General Principles
- •4.5 Possible Secondary Extensions
- •5 Conclusion
- •References
- •8 Clinical Assessment of Crohn Perianal Abscesses and Fistulas
- •1 Introduction
- •1.2 Inspection
- •1.3 Palpation
- •1.4 Endoscopy
- •2 Clinical Presentation
- •2.1 Skin Lesions
- •2.2 Fistulas
- •2.3 Abscesses
- •2.4 Diagnostic Workup
- •2.4.1 General Principles
- •2.5 US
- •2.6 Effectiveness and Sensitivity
- •2.6.1 Endoscopy
- •2.7 MRI
- •2.7.1 CT Scan
- •2.7.2 Fistulography
- •2.8 Diagnostic Follow-up
- •References
- •9 Anorectal Physiology Assessment in Patients with Anal Fistula: When Necessary
- •1 Introduction
- •2 Anorectal Physiology Assessment
- •2.1 Anamnesis
- •2.2 Physical Examination
- •2.3 Anorectal Manometry
- •2.3.1 Equipment
- •2.3.2 Manometry Systems
- •2.4 Neurophysiologic Tests
- •2.4.1 Electromyography
- •2.4.2 Nerve Conduction Studies
- •2.5 Endoanal Ultrasound
- •2.6 Role of Anorectal Physiology Patterns in the Decision-Making
- •3 Discussion
- •References
- •1 Introduction
- •2 Anal Anatomy
- •3 Classification of Fistulas
- •4 EAUS Imaging
- •4.1 Probes EAUS
- •4.2 Performing EAUS
- •4.3 EUS in Perianal Fistulas
- •4.4 Adding Hydrogen Peroxide (H2O2)
- •4.5 Cryptoglandular Fistulas
- •5 Comparison with Other Diagnostic Modalities
- •5.1 Comparison with Surgery
- •5.2 Comparison with MRI
- •5.3 Perineal Ultrasound
- •6 Conclusion and Recommendation
- •References
- •1 Introduction
- •2 Imaging
- •2.1 Conventional Contrast Material-Enhanced Fistulography
- •2.2 CT
- •2.3 Magnetic Resonance Imaging
- •2.3.1 Anatomy MRI
- •2.3.2 MRI Technique (Coils, Volume, and Sequences) and Findings
- •2.3.3 MRI Reconstruction Techniques and Fistulography MRI
- •2.3.4 Internal and Cutaneous Opening
- •2.3.5 Classifications of Perianal Fistulas and Abscesses
- •2.3.6 Deep Posterior Anal Fistulas and Abscess
- •2.3.7 MRI Report
- •2.3.9 MR Role in the Evaluation of the Crypto-Glandular Fistulas
- •3 Conclusion
- •4 Cross-References
- •References
- •1 Introduction
- •2 Clinical Presentation
- •3 Utility and Limitations of Endoanal Ultrasound
- •4 Conclusion
- •5 Cross-References
- •References
- •1 Introduction
- •2 Imaging
- •3 Diagnosis
- •4 MRI Technique
- •5 Disease Monitoring
- •6 Future Directions
- •7 Conclusion
- •8 Cross-References
- •References
- •14 Future Perspectives in the Diagnosis of Anal Fistula and Abscess
- •1 Introduction
- •2 Assessment of Abscess and Anal Fistula
- •3 Abscess
- •3.1 Computed Tomography (CT)
- •3.2 Magnetic Resonance Imaging (MRI)
- •3.3 Endoanal Ultrasound
- •3.4 Transperineal Ultrasonography (TP-US)
- •4 Anal Fistula
- •4.1 Imaging
- •4.1.1 Endoanal Ultrasound
- •4.1.2 Magnetic Resonance Imaging
- •5 Conclusion
- •6 Cross-References
- •References
- •15 How to Drain an Abscess
- •1 Introduction
- •2 Epidemiology and Etiology
- •3 Classification
- •4 Clinical Manifestations and Diagnosis
- •5 Management
- •7 Wound Dressing
- •8 Microbiology and Antibiotics
- •9 General Postoperative Management
- •10 Conclusion
- •11 Cross-References
- •References
- •16 The Seton in Anal Fistula Management
- •1 Introduction
- •2 2500 Years of Setons
- •3 To Put or Not to Put
- •4 To Cut or Not to Cut
- •5 What Kind of Seton to Use?
- •7 Seton 2.0: New Perspectives
- •8 Uncomfortable Questions (How to Do It)
- •9 What Patients Should Know
- •10 Conclusions: Seton in Guidelines
- •References
- •17 Fistulotomy
- •1 Introduction
- •2 Indications
- •3 Fistulotomy: Standard Technique
- •4 Other Fistulotomy Techniques
- •4.1 Addition of Loose Seton
- •4.2 Slow Dissection of the Sphincter: Cutting Seton
- •4.3 Addition of Marsupialization
- •5 Fistulotomy with Immediate Primary Sphincteroplasty (FIPS)
- •7 Postoperative Care
- •8 Complications and Recurrence Rate
- •9 Discussion
- •10 Conclusion
- •References
- •18 Fistulectomy
- •1 Introduction
- •2 Preoperative Evaluation
- •2.1 Patient Selection
- •2.2 Imaging
- •2.3 Physiologic Testing
- •2.4 Endoscopic Examination
- •3 Technique
- •3.1 Patient Preparation
- •3.2 Patient Positioning
- •3.2.1 Technical Steps
- •4 Postoperative Care
- •5 Results
- •5.1 Fistulectomy
- •6 Fistulectomy with Sphincter Reconstruction
- •7 Conclusions
- •References
- •19 Utility of Adding Sphincter Reconstruction to Fistulotomy/Fistulectomy
- •1 Introduction
- •2 General Classification
- •3 Preoperative Preparation
- •4 Surgical Technique Step by Step
- •5 Results
- •6 Conclusion
- •7 Cross-References
- •References
- •20 Utility of Marsupialization Following Anal Fistula Surgery
- •1 Introduction
- •2 Marsupialization
- •3 Clinical Evidence
- •4 Conclusion
- •References
- •21 Transanal Advancement Flap Repair
- •1 Introduction
- •2 Nomenclature
- •3 Effectiveness of the Technique
- •4 Effectiveness of Repeat Procedures
- •5 Impact on Fecal Continence
- •6 Severity of Incontinence
- •7 Perioperative Care
- •7.1 Bowel Preparation
- •7.2 Antibiotic Prophylaxis
- •7.3 Prolonged Antibiotic Therapy
- •7.4 Type of Anesthesia
- •7.5 Immobilization
- •7.6 Bowel Confinement
- •7.7 Stool Softeners
- •7.8 Position
- •8 Aspects of Surgical Technique
- •8.1 Preoperative Care
- •8.2 Step 1
- •8.3 Step 2
- •8.4 Step 3
- •8.5 Step 4
- •8.6 Step 5
- •8.7 Postoperative Care
- •8.8 Types of Flap
- •8.9 Shape of Flap
- •8.10 Thickness of Flap
- •8.11 Addition of Accessory Techniques
- •9 Necessity of Preoperative Imaging
- •10 Factors Contributing to Successful Healing
- •10.1 Fistula-Related Factors
- •10.2 Patient-Related Factors
- •10.3 Influence of Covering Ostomy
- •10.4 Impact of the Use of Draining Setons
- •11 Conclusion
- •References
- •22 Dermal Flap Anoplasty for Trans-sphincteric Anal Fistula
- •1 Rationale
- •2 Technique
- •3 Other Dermal Flaps
- •4 Discussion
- •5 Cross-References
- •References
- •23 (LIFT) Ligation of Intersphincteric Fistula Tract
- •References
- •24 Anal Fistula: Glue and Paste Injection
- •1 Introduction
- •2 Fibrin Glue
- •3 Collagen Paste
- •4 Conclusion
- •5 Cross-References
- •References
- •25 VAAFT
- •1 Introduction
- •1.1 VAAFT Story
- •2 Surgical Equipment and Accessories
- •3 VAAFT Indications
- •3.1 Preoperative Assessment
- •4 VAAFT Procedure
- •4.1 Diagnostic Phase (Fistuloscopy)
- •4.2 Operative Phase
- •5 Closure of the Internal Opening
- •5.1 Use of a Linear or Semicircular Stapler
- •5.2 Advancement Flap
- •5.3 Use of a Bioabsorbable Mesh (Xenograft)
- •5.4 Autologous Dermis Graft
- •5.4.1 VAAFT Associated to the LIFT Procedure
- •5.5 Postoperative Management
- •6 Discussion
- •7 Conclusions
- •References
- •26 The Laser Treatment of Anal Fistulas
- •1 Introduction
- •1.1 Literature Review
- •1.3 Diagnosis and Treatment of Complex Anal Fistulas
- •2 Materials and Methods
- •3 Conclusion
- •References
- •27 Treatment by Over-the-Scope-Clip
- •1 Introduction
- •2 Technical Background
- •3 Surgical Application
- •4 Principle of Action
- •5 Clinical Data
- •References
- •28 Stem Cells in Cryptoglandular Anal Fistulas
- •1 Introduction
- •2 History of a Novel Approach
- •2.1 Mesenchymal Stem Cells
- •2.2 Adipose Tissue: The Ideal MSCs Source
- •2.3 Adipose Tissue Graft
- •2.3.1 Lipogems
- •3 Results
- •3.1 Literature Review
- •3.2 Personal Experience
- •4 Discussion and Conclusion
- •References
- •1 Introduction
- •2 Perianal and Rectovaginal Fistulas
- •2.1 Epidemiology and Diagnosis
- •2.2 Classification
- •2.3 Treatment Modalities
- •3 Flap Reconstruction
- •3.1 Overview and Considerations for Flap Reconstruction
- •4 Gracilis Interposition Flap
- •4.1 Background and Indications
- •4.2 Operative Technique
- •4.3 Results/Complications
- •5 Martius Interposition Flap
- •5.1 History and Indications
- •5.2 Surgical Technique
- •5.3 Results/Complications
- •6 Gluteal Muscle Interposition Flap
- •6.1 History and Indications
- •6.2 Surgical Technique
- •6.3 Results/Complications
- •7 Conclusion
- •References
- •30 Quality of Life Following Anal Fistula Treatment
- •1 Introduction
- •2 Quality of Life with an Anal Fistula
- •2.1 Cryptoglandular Fistulas
- •2.3 Conclusion
- •3 Quality of Life with a Seton and a Fistula

18 Fistulectomy 293
Fig. 8 Pudendal nerve
terminal motor latency
(PNTML) testing and anal
electromyography (EMG)
equipment
Fig. 9 Terminal ileal deep
and wide ulcerations noted on
colonoscopy in a patient who
presented with anal fistula.
Biopsies confirmed Crohn’s
disease with granulomas

294 M. A. Abbas
3.2 Patient Positioning
While fistulectomy can be performed in the lithotomy position, my personal preference is the prone jackknife position (Fig. 10) which provides ample access to the
anus and the perineum. Retracting the buttocks laterally and securing them in place
with tape offers the surgeon and the assistant great exposure to the surgical field. The
prone jackknife position allows for clear visualization of the anal region. With the
surgeon on one side of the patient and the assistant on the opposite side, it offers
both surgeon and assistant the unhindered physical space to conduct the operation
with ease.
Fig. 10 Prone jackknife position

18 Fistulectomy 295
3.2.1 Technical Steps
Fistulectomy can be achieved by two different techniques: (1) the coring-out technique with en bloc excision of the entire fistula tract including skin, subcutaneous
tissue, fistula tract, and surrounding cuff of sphincter muscle with closure of the
intramuscular portion of the internal opening or (2) division of the fistula over a
probe and limiting the excision to the epithelialized tract of the fistula. I prefer the
second option as it is done under direct visualization and it minimizes any potent ial
anal sphincter damage and loss especi ally to the proximal portion of the sphincter
cephalad to the fistulous tract. Furthermore, in select group of patients, it allows for
the proper exposure for sphincter muscle repair.
The anorectum is evacuated of any residual stool and irrigated with an antiseptic
solution such as betadine. Rigid proctoscopy is often helpful to inspect the cleanness
of the rectum, to perform betadine antiseptic irrigation, and to exclude any other
rectal pathology including proctitis. The first step of the operation is to clearly
identify the internal openin g of the fistula with the passage of a probe from the
external to the internal opening. If there is an existing seton, it is removed after
clearly marking the internal opening. If no seton is present, hydrogen peroxide
injection can be helpful in delineating the internal opening. With the fistula probe
inserted inside the fistula, 0.5% bupivacaine solution is injected into the tissue
surrounding the fistula for preemptive analgesia (Fig. 11).
Fig. 11 0.5% bupivacaine
injected into the tissue
surrounding the fistula for
preemptive analgesia

296 M. A. Abbas
Fig. 12 The Pratt bivalve
speculum
An anoscope is used for anal exposure. I prefer the Pratt bivalve speculum for
most of my proctologic cases (Fig. 12). The probe is advanced from the external to
the internal opening until it clearly protrudes into the anal canal (Fig. 13). Electrocautery (thermal cautery) is used to divide the tract over the probe. Care is taken to
divide the tissue in a perpendicular fashion, avoiding a tangential oblique dissection
which leads to more muscle division (Fig. 14). Once the division of the fistula is
completed into the lumen of the anus, the immediate tissue surrounding the fistulous
tract is infiltrated with additional 0.5% bupivacaine anesthetic to create a buffer
dissection plane between the epithelialized tract and the adjacent sphincter muscle
(Fig. 15). Using fine tip tenotomy scissors and tooth forceps (Fig. 16), the
epithelialized tract is separated from the surrounding muscular cuff for a precise
dissection with minimal damage to the anal sphincter (Fig. 17). The excised tissue is
sent for histopathologic evaluation. The mucosal aspect of the internal opening and
surrounding glands is fulgurated with electrocautery (Fig. 18). In order to reduce the
wound size, the edge of the skin is marsupialized to the center of the wound using a
running 2.0 Vicryl (polyglycolic acid) suture from the distal anus to the anoderm
portion of the wound (Fig. 19). At the completion of the marsupialization, the wound
center is open to promote adequate drainage and minimize the risks of postoperative
sepsis (Fig. 20).
Fistulectomy with sphincter reconstruction can be considered in some patients. It
is achieved by approximation of the external sphincter muscle using a row of

18 Fistulectomy 297
Fig. 13 The fistula probe
linking the external with the
internal fistula opening
horizontal mattress stitches. Care is taken to avoid recreating a fistulous tract
underneath the reconstruction. The technique of sphincter repair following
fistulotomy or fistulectomy is described in detail in another chapter in this book
and previous publications (Ratto et al. 2013, 2015; Litta et al. 2019).
4 Postoperative Care
Fistulectomy is undertaken on an outpatient basis in the majority of patients.
Discharge to home is achieved after a short period of observation in the postoperative recovery unit. Once discharge criteria are met and the patient is able to void
urine, the patient is discharged home. Overnight observation can be considered in
patients with significant medical comorbidities, large wounds with significant pain
issues, or those who undergo sphincter reconstruction and have muscle spasm pain
requiring intravenous medications or urination issues necessitating bladder
catheterization.
When sphincter repair is undertaken, the patient may experience some degree of
muscular spasm for a few days which is best treated with a benzodiazepine muscle
relaxant such as diazepam. In most patients, postoperative pain is adequately
controlled with paracetamol and nonsteroidal anti-inflammatory medications
(NSAIDS) such as ibuprofen, naproxen, or diclofenac. Severe pain can be relieved

298 M. A. Abbas
Fig. 14 Electrocautery
divides the tract over the
fistula probe in a
perpendicular fashion
with a short course of tramadol or a codeine-based medication such as oxycodone or
hydrocodone. I reserve oral antibiotics for patients who undergo sphincter reconstruction. A 1-week course of a combination of ciprofloxacin and metronidazole or a
cephalosporin and metronidazole is sufficient. Postoperative constipation should be
avoided. A bulking agent such as psyllium husk is recommended once or twice a day
and if needed, with the addition of a gentle laxative such as bisacodyl tablets or
lactulose syrup.
The patient is advised to perform a 15-minute sitz bath in warm water twice a day
for 2 weeks. A thin wet to dry gauze dressing is used as a wick inside the depth of the
wound and changed twice a day for 1 to 2 weeks depending on the size of the wound.
The first postoperative visit is scheduled between 10 and 14 days and every 2 weeks
thereafter until the wound is healed.
5 Results
The interpretation of outcome data is critical when managing patients with anal
fistula. It is important to note that the current literature on anal fistula treatment is
mostly retrospective in nature. Such studies are challenging to understand due to

18 Fistulectomy 299
Fig. 15 Additional 0.5%
bupivacaine injection into the
tissue cuff surrounding the
divided fistula to create a
buffer plane for dissection
their heterogene ity and lack of standardization in de fining various variables
related to the disease, intervention, and outcome measures. An ideal literature
and data would include standard reporting par ameters of patie nt and fistula
characteristics, prior interventions, a detailed description of operative technique,
a clearly defined set of outcome variables, and a minimum follow-up period. All
of these elements are important for an accurate comparison of results. F or
instance, the difference in terminology for persistent vs. recurren t disease is
often blurred and inconsistent. Some failures are classified as recurrence, when
in reality they should be reported as persistence of the disease. Furthermore, most
studies combine both failure and recurrent disease as one outcome va riable of
recurrence. Similarly, many studies do not make a clear distinction between
fistulotomy whic h entails division of the fistula only vs. fistulectomy which
necessitates excision of the fistulous tract. Academically speaking, the terms of
fistulotomy a nd fistulectomy should not be used interchangeably as reported in
some studies even when fistulectomy is limited to excision of the fistulous t ract
without any muscle. An additional challenge is the sporadic and loose reporting
of functional outcome and the lack of adequate follow-up to assess the long-term
outcome. With those limitations in mind, the following section presents some of
the results reported for this technique.

300 M. A. Abbas
Fig. 16 Fine tip tenotomy
scissors and tooth forceps
5.1 Fistulectomy
Sheikh and colleagues compared the outcome of fistulotomy and fistulectomy in
262 male patients with low lying anal fistula (Sheikh et al. 2015). Mean healing
time was 4.04 weeks in the fistulotomy group vs. 4.57 weeks in patients undergoing fistulectomy ( p ¼ 0.108). The recurrence rate was slightly lower in the
fistulotomy group compared to the fistulectomy group (10.7% vs. 15.3%,
p ¼ 0.27). Salem reported his experience with 272 patients treated for low anal
fistula over a 10-year period (Salem 2012). The mean follow-up was 12 months
(range 1–24). Recurrence rate was 6% in patients who underwent fi stulectomy and
10% in those with fistulotomy. The reported healing time was 3 weeks vs. 4 weeks
in the fistulectomy and fistulotomy groups, respectively. Barase and Shinde
reported a comparative study of fistulotomy and fistulectomy in the management
of 84 patients with simple anal fistula (Barase and Shinde 2018). The patients were
equally divided into the two groups. The median duration of healing was shorter in
the fistulotomy group (12 days vs. 21 days, p < 0.001). During a mean follow-up
of 6 months, a recurrence rate of 2.38% was similar in both groups. Kanchwala and
colleagues studied the recurrence rates after fistulotomy and fistulectomy
(Kanchwala et al. 2018). They tracked 110 patients undergoing fistulect omy and
fistulotomy for primary or recurrent low anal fistula for 6 months. Recurrence rate
was9.4%vs.12.3%inthefistulectomy and fistulotomy groups, respectively

18 Fistulectomy 301
Fig. 17 Fine tip tenotomy
scissor dissects the
epithelialized tract off the
surrounding sphincter muscle
minimizing any damage to
anal musculature
( p ¼ 0.763). Tobisch and colleagues reported their results w ith total fistulectomy
with simple closure of the internal opening in the management of complex
cryptoglandular fistulas (Tobisch et al. 2012). A total of 252 patients were studied
with a median follow-up of 70 months (range 14–141). Fistula closure was noted in
74% of the patients. The success rate was highest in patients with posterior transsphincteric or supra-sphincteric fistulas compared to other types of fistulas (82%
vs. 67%, p ¼ 0.014). Athanasiadis and colleagues prospectively studied
169 patients with high fist ula who underwent fistulectomy with occlusion of the
internal fistula opening (Athanasiadis et al. 1991). A total of 147 patients had high
trans-sphincteric fistula and 22 presented with supra-sphincteric. Their modified
technique included one-stage fistulectomy with the addition of internal
sphincterotomy for the drainage of the intersphincteric space. The internal aspect
of the intramuscular aspect of the fistula was closed and the external aspect was left
open to heal by secondary intention. During a mean follow-up of 3.2 years,
32 patients (18.9%) required re-operation for recurrent abscess or fi stula of immediate failure of the procedure.
Fistulectomy is overall safe with a low rate of postoperative complications.
Sheikh and colleagues reported an incidence of postoperative bleeding in 3.1% of
patients and infections in 3.8% (Sheikh et al. 2015). In their study of 252 patients,
Tobisch and colleagues reported early reoperation in 12 patients (4.76%) for suture
line dehiscence (Tobisch et al. 2012).

302 M. A. Abbas
Fig. 18 Fulguration of the
mucosal aspect of the internal
opening and surrounding
glands to minimize recurrence
In his study of 146 patients undergoing fistulectomy for low fistula, Salem
reported no incontinence (Salem 2012). However, it is unclear whether formal
surveying or assessment of the patients was conducted to carefully document any
continence disturbance. In the study reported by Barase, the incontinence rate was
11.9% in the fistulotomy patients compared to 2.38% in fistulectomy ( p < 0.05)
(Barase and Shinde 2 018). Kanchwala and colleagues assessed patient’s incontinence in 110 patients using the Cleveland Clinic Florida Incontinence score
(Kanchwala et al. 2018). At 6 months follow-up, continence level was normal in
92.5% vs. 91.2% of the fistulectomy and fistulotomy groups, respectively
( p ¼ 0.564). However, such a high continence rate was not noted in the study by
Tobisch and colleagues who meas ured continence using the same scale (Tobisch
et al. 2012). Normal postoperative continence was noted in only 56% of the healed
patients without prior anal fistula surgery. In their prospective study, Athanasiadis
and colleagues performed preoperative and postoperative anal manometry in their
patients. They noted a decrease in anal rest ing and squeeze pressure of 10 to 40%
from baseline with an approximate average of 30% (Athanasiadis et al. 1991). A
postoperative impairment of continence was noted in 15% of the patients who had
not been previously operated and in 40% of patients with previous operations. In the
majority of those patients, soiling was noted but total incontinence to formed stool
was not noted.
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