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About the Editors

Prof. Carlo Ratto was born in Naples, Italy, on July 6, 1962. He completed his graduation in medicine and surgery at the Catholic University of Rome in 1987 and specialized in emergency surgery at the Catholic Uni­versity of Rome in 1992. He is a colorectal surgeon, experienced in clinical and scientic research, training and educational support, and innovations in coloproctology. His clinical practice concerns particu­larly the colo-recto-anal disorders and diseases. He was coordinator of several scientic projects, with pub­lication of results in prestigious scientic journals. He has been editor of books on different topics in coloproctology. He was Scientic Director and Member of Board of numerous training and master courses, meetings, and congresses. Prof. Ratto is an active mem­ber of the most prestigious scientic societies in coloproctology. He was frequently involved, as invited speaker, in a number of national and international con­gresses and meetings, and he has also performed live surgery.
He is active member of
– American Society of Colon and Rectal Surgeons
(ASCRS), Fellow
European Society of Coloproctology (ESCP)International Anal Neoplasia Society (IANS)
Prof. Ratto was/is member of the several committees
of the ASCRS.
Prof. Ratto is member of the editorial board of sev-
eral scientic journals.
xi
xii About the Editors
Dr. Angelo Parello was born in Agrigento, Italy, on
October 17, 1980. He graduated with honors in medi­cine and surgery from the Catholic University of Rome in 2004. From 2004 to 2010, he was resident in general surgery at the Catholic University of Rome, which he attended with particular interest directed to diagnosis and treatment of coloproctological diseases.
His clinical practice is mainly directed to diagnosis and treatment of colo-rectal-anal diseases, and he is an expert in performing both anorectal and pelvic oor diagnostics tests (e.g., anorectal manometry and endoanal and transrectal ultrasound) and treatment (e.g., transanal hemorrhoidal Doppler-guided dearterialization for hem­orrhoidal disease, and sacral neuromodulation for fecal incontinence and constipation).
Dr. Parello collaborated in the development of a novel minimally invasive surgical approach to treat fecal incontinence – THD implant Gatekeeper and SphinKeeper.
He was teacher and tutor in many national and inter­national courses conducted in Italy and other European countries.
Dr. Parello is author of several scientic publications in international journals and author of several book chapters, and has presented his research results at national and international scientic conferences.
Dr. Francesco Litta was born in Matera on April 25, 1983. He graduated with honors in medicine and surgery from the Catholic University of Rome in 2008. He is a specialist in general surgery.
Dr. Litta is a consultant surgeon in the Proctology Unit at the Foundation University Hospital A. Gemelli,IRCCS, Rome, Italy.
His clinical practice focuses mainly on the diagnosis and treatment of disease of the colon and the rectum, and all proctological diseases. He is involved in anorectal physiology testing, with particular interest in the evalu­ation of benign and malignant disease by means of the anorectal manometry, three-dimensional endoanal ultra­sound, and the high-resolution anoscopy.
His research activity is mainly based on the evalua­tion and treatment of patients affected by anal stula, fecal incontinence, constipation, hemorrhoidal disease,
About the Editors xiii
obstructed defecation syndrome, and inammatory bowel diseases, with studies concerning pathophysiol­ogy and surgical treatment by means of traditional and new minimally invasive therapeutic options.
Dr. Litta is author of several scientic publications in international journals and author of several book chap­ters, and has presented his research results at national and international scientic conferences. He is teacher in a series of national and international courses on the management of coloproctological diseases.
Dr. Litta is active member of the European Society of Coloproctology (ESCP), and member of the Guidelines Committee on the diagnosis and treatment of cryptoglandular perianal stula, on behalf of this Society.
Dr. Veronica De Simone was born in Avellino, Italy, on January 4, 1987. She graduated with honors in med­icine and surgery from the Catholic University of Rome in 2011 (110/110 cum laude).
She completed her training in general surgery at the Catholic University of Rome (2012–2017).
She works in the Proctology Unit at the Foundation University Hospital A. Gemelli,Rome, Italy.
Her clinical practice concerns the diagnosis and treat­ment of benign and malignant colorectal and anal dis­eases. She developed a particular expertise in the diagnosis and management of anal and perianal HPV-related disease, performing anal cancer screen ing and second-level diagnostic tests (high resolution anoscopy) in high-risk population (HIV+, transplant recipients, and inammatory bowel diseases).
She is expert in performing anorectal diagnostics tests (e.g., anorectal manometry, and endoanal and transrectal ultrasound), in particular for the diagnostic evaluation of patients affected by fecal incontinence, obstructed defecation, and anal stula and abscess. She is also involved in multidisciplinary team for the diag­nosis, treatment, and follow-up of patients affected by rectal and anal cancer.
Her research activity is mainly based on the evalua­tion and treatment of patients affected by fecal inconti­nence, anal HPV-related diseases, and anorectal dysfunctional outcomes after rectal resection surgery.
xiv About the Editors
She is author of several scientic publications in international journals and has presented her research results at national and international scientic confer­ences. She is teacher in a series of national and interna­tional courses on the diagnosis and treatment of colorectal diseases.
Dr. Paola Campennì was born in Vibo Valentia, Italy, on January 17, 1984. She graduated with honors in medicine and surgery from the University of Rome La Sapienzain October 2008 with an experimental research about transanal endoscopic microsurgery for rectal cancer.
She worked as resident in the Digestive Surgery Unit at the University of Udine, and she focused on colorectal diseases and minimally invasive surgery at the Univer­sity of Milan.
In May 2015, she concluded her surgical training with honors and published her degree thesis.
From 2016 to 2019, she worked at Humanitas Research Hospital, Rozzano (MI), as colorectal surgeon and at Humanitas University as clinical tutor for medi­cine and surgery students (cours e of SimulationLab: patients management).
She is now a staff surgeon in the Proctology Unit at the Foundation University Hospital A. Gemelli, Rome, Italy, and consultant proctologist at Mater Olbia Hospital, Olbia, Italy. She is mainly dedicated to treat­ment of:
– Proctological diseases (hemorrhoidal disease, anal
ssure, anal stula, anorectal abscess, proctitis,
HPV infection, and anorectal dysplasia/cancer) – Chronic inammatory bowel disea ses (Crohn disease
and ulcerative colitis) – Pelvic Disorders (complete rectal prolapse, internal
intussusception, rectocele, obstructed defecation syn-
drome, and fecal incontinence)
She routinely performs endoanal and transrectal ultrasound, anorectal manometry, and high-resolution anoscopy, and she is actively involved in the conserva­tive treatment of fecal incontinence by the adoptio n of percutaneous tibial nerve stimulation (PTNS).
About the Editors xv
She is author of several papers concerning functional disorders and rectal cancer.
She is one of the founders of the Young Group of Italian Society of Colorectal Surgery (SICCR-Y), secre­tary from 2017 to 2019, and promoter of numerous multicenter studies.

Contributors

Maher A. Abbas Kings College Hospital London, Dubai, UAE
Michel Adamina Department of Surgery, Cantonal Hospital Winterthur, Winter-
thur, Switzerland Faculty of Medicine, University of Basel, Basel, Switzerland
Rebecca Aglietti Proctology and Pelvic Floor Clinical Centre, Cisanello University Hospital, Pisa, Italy
Alessandro Armuzzi Dipartimento Universitario di Medicina e Chirurgia Traslazionale, Università Cattolica del Sacro Cuore, Rome, Italy
UOC di Medicina Interna e Gastroenterologia; CEMAD – IBD UNIT; Dipartimento di Scienze Mediche e Chirurgiche, Fondazione Policlinico Universitario A. GemelliIRCCS, Rome, Italy
Manuel Aubert Service de Proctologie Médico-Chirurgicale, Groupe hospitalier Paris Saint-Joseph, Institut Léopold Bellan, Paris, France
Heeva Baharlou Centre for Virus Research, The Westmead Institute for Medical Research, Westmead, NSW, Australia
The University of Sydney, School of Medical Sciences, Faculty of Medicine and Health Sydney, Sydney, Australia
Izaskun Balciscueta Surgery Unit, Hospital Universitario La Ribera, Alzira, Spain
Zutoia Balciscueta Colorectal Surgery Unit, Hospital Arnau de Vilanova, Valen-
cia, Spain
Nadav Ben David Division of Colon and Rectal Surgery, Humanitas Clinical and Research Center IRCCS, Milan, Italy
Paul Benfredj Service de Proctologie Médico-Chirurgicale, Groupe hospitalier Paris Saint-Joseph, Institut Léopold Bellan, Paris, France
Antonio Bevere Università Cattolica del Sacro Cuore, Istituto di Radiologia, Rome, Italy
xvii
xviii Contributors
Birgit Bittorf Department of Surgery, University Erlangen, Erlangen, Germany
Andrea Bondurri General Surgery, Luigi Sacco University Hospital, Milan, Italy
M. E. Bos Department of Surgery, Proctos Kliniek, Bilthoven, The Netherlands
Luigi Brusciano Division of General, Mini-invasive and Obesity Surgery, Univer-
sity of Study of Campania Luigi Vanvitelli, Naples, Italy
Paola Campennì Proctology Unit, Dept. of Medical and Surgical Sciences, Foun­dation University Hospital A. Gemelli, IRCCS, Rome, Italy
Kirsty R. Cattle Mid and South Essex Hospitals NHS Foundation Trust, Chelms­ford, UK
Giovanni Cimino Università Cattolica del Sacro Cuore, Istituto di Radiologia, Rome, Italy
Jacopo Crippa Division of Colon and Rectal Surgery, Humanitas Clinical and Research Center IRCCS, Milan, Italy
Vincent de Parades Service de Proctologie Médico-Chirurgicale, Groupe hospitalier Paris Saint-Joseph, Institut Léopold Bellan, Paris, France
Veronica De Simone Proctology Unit, Dept. of Medical and Surgical Sciences, Foundation University Hospital A. Gemelli, IRCCS, Rome, Italy
Eloy Espin-Basany Colorectal Surgery Unit. Servei de Cirurgia General, Hospital Vall dHebrón. Universitat Autonoma de Barcelona, Barcelona, Spain
Bernardina Fabiani Proctology and Pelvic Floor Clinical Centre, Cisanello Uni­versity Hospital, Pisa, Italy
Nadia Fathallah Service de Proctologie Médico-Chirurgicale, Groupe hospitalier Paris Saint-Joseph, Institut Léopold Bellan, Paris, France
Richelle J. F. Felt-Bersma Department of Gastroenterology and Hepatology, Amsterdam University Medical Centre, Amsterdam, The Netherlands
Proctos Clinic, Bilthoven, The Netherlands
Lorenzo Ferri Proctology Unit, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Largo A. Gemelli, Rome, Italy
Caterina Foppa IRCCS Humanitas Research Hospital, Milan, Italy Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan,
Italy
Jace Franko Department of Surgery, Madigan Army Medical Center, Fort Lewis, WA, USA
Contributors xix
Giuseppe Gagliardi University of Illinois at Chicago School of Medicine Depart­ment of Surgery, Chicago, IL, USA
Chicago Surgical Clinic, Chicago, IL, USA
Álvaro García-Granero Colorectal Surgery Unit, Hospital Universitario Son Espases, Mallorca, Spain
M. Garcia-Arranz Department of Surgery, University Hospital Fundación Jiménez Díaz, Madrid, Spain
New Therapy Laboratory, Instituto de Investigación Sanitaria Fundación Jiménez Díaz, Madrid, Spain
Surgery Department, Universidad Autonoma de Madrid, Madrid, Spain
D. Garcia-Olmo Department of Surgery, University Hospital Fundación Jiménez Díaz, Madrid, Spain
New Therapy Laboratory, Instituto de Investigación Sanitaria Fundación Jiménez Díaz, Madrid, Spain
Surgery Department, Universidad Autonoma de Madrid, Madrid, Spain
Pankaj Garg Colorectal Surgery, Garg Fistula Research Institute, Panchkula, India
Ibrahim Ethem Gecim Colorectal Unit, Ankara University Medical School,
Ankara, Turkey
Martijn P. Gosselink Department of Surgery, Dr. Horacio E. Oduber Hospital, Oranjestad, Aruba
H. Guadalajara Department of Surgery, University Hospital Fundación Jiménez Díaz, Madrid, Spain
New Therapy Laboratory, Instituto de Investigación Sanitaria Fundación Jiménez Díaz, Madrid, Spain
Surgery Department, Universidad Autonoma de Madrid, Madrid, Spain
Dieter Hahnloser Department of Visceral Surgery, University Hospital Lausanne, Lausanne, Switzerland
Toby M. Hammond Mid and South Essex Hospitals NHS Foundation Trust, Chelmsford, UK
Alexander Herold Deutsches End- und Dickdarm-Zentrum, Mannheim, Germany
Luigi Larosa Fondazione Policlinico Universitario A. Gemelli IRCCS, UOC di
Radiologia Diagnostica e Interventistica Generale, Dipartimento di Diagnostica per immagini, Radioterapia Oncologica ed Ematologia, Rome, Italy
Lucrezia Laterza Università Cattolica del Sacro Cuore, Rome, Italy
xx Contributors
M. Leon Department of Surgery, University Hospital Fundación Jiménez Díaz, Madrid, Spain
New Therapy Laboratory, Instituto de Investigación Sanitaria Fundación Jiménez Díaz, Madrid, Spain
Francesco Litta Proctology Unit, Dept. of Medical and Surgical Sciences, Foun­dation University Hospital A. Gemelli, IRCCS, Rome, Italy
Loris Riccardo Lopetuso Università Cattolica del Sacro Cuore, Rome, Italy
Phillip F. C. Lung Fistula Research Unit, St Marks Hospital and Academic
Institute, Harrow, UK
Y. Maeda Department of Colorectal Surgery, University of Edinburgh, Western General Hospital, Edinburgh, UK
Riccardo Manfredi Fondazione Policlinico Universitario A. Gemelli IRCCS, UOC di Radiologia Diagnostica e Interventistica Generale, Dipartimento di Diagnostica per immagini, Radioterapia Oncologica ed Ematologia, Rome, Italy
Università Cattolica del Sacro Cuore, Istituto di Radiologia, Rome, Italy
Franco Marinello Colorectal Surgery Unit. Servei de Cirurgia General, Hospital Vall dHebrón. Universitat Autonoma de Barcelona, Barcelona, Spain
Angelo Alessandro Marra Proctology Unit, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Largo A. Gemelli, Rome, Italy
Jacopo Martellucci Emergency Surgery/Pelvic Floor Center, Careggi University Hospital, Florence, Italy
Klaus E. Matzel Department of Surgery, University Erlangen, Erlangen, Germany
Piercarlo Meinero Minimally-Invasive Proctology Center, Montallegro Clinic,
Genoa, Italy Beata VergineHospit al, Mendrisio, Switzerland
Claudia Menconi Division of General, Mini-invasive and Obes ity Surgery, Uni­versity of Study of Campania Luigi Vanvitelli, Naples, Italy
Proctology and Pelvic Floor Clinical Centre, Cisanello University Hospital, Pisa, Italy
Laura Maria Minordi Fondazione Policlinico Universitario A. Gemelli IRCCS, UOC di Radiologia Diagnostica e Interventistica Generale, Dipartimento di Diagnostica per immagini, Radioterapia Oncologica ed Ematologia, Rome, Italy
C. B. H. Molena ar Department of Surgery, Proctos Clinic, Bilthoven, The Netherlands
Douglas Morte Department of Surgery, Madigan Army Medical Center, Fort
Lewis, WA, USA
Contributors xxi
Sthela Murad-Regadas School of Medicine, Federal University of Ceara, Forta­leza, Ceará, Brazil
Gabriele Naldini Division of General, Mini-invasive and Obesity Surgery, Uni­versity of Study of Campania Luigi Vanvitelli, Naples, Italy
Proctology and Pelvic Floor Clinical Centre, Cisanello University Hospital, Pisa, Italy
Richard Nelson University of Illinois at Chicago School of Public Health, Epide­miology/Biometry Division, Chicago, IL, USA
Lucia Camara Castro Oliveira Department of Anorectal Physiology of Rio de Janeiro, CEPEMED, Rio de Janeiro, Brazil
Angelo Parello Proctology Unit, Dept. of Medical and Surgical Sciences, Founda­tion University Hospital A. Gemelli, IRCCS, Rome, Italy
Gianluca Pellino Colorectal Surgery, Vall dHebron University Hospital, Barce- lona, Spain
Department of Advanced Medical and Surgical Sciences, Università degli Studi della Campania Luigi Vanvitelli, Naples, Italy
Marco Pizzoferrato Università Cattolica del Sacro Cuore, Rome, Italy
Vlasta Podzemny General, Emergency and Minimally Invasive Surgery, Careggi
University Hospital, Florence, Italy
Elise Pommaret Service de Proctologie Médico-Chirurgicale, Groupe hospitalier Paris Saint-Joseph, Institut Léopold Bellan, Paris, France
Felipe Celedon Porzio Department of Coloproctological Surgery, Hospital de la Fuerza Aerea de Chile, Santiago de Chile, Chile
Proctology and Pelvic Floor Clinical Centre, Cisanello University Hospital, Pisa, Italy
Gioia Pozza Department of Surgery, Cantonal Hospital Winterthur, Winterthur, Switzerland
Department of Surgery, University of Trieste, Trieste, Italy
Giuseppe Privitera Dipartimento Universitario di Medicina e Chirurgia Traslazionale, Università Cattolica del Sacro Cuore, Rome, Italy
Ruediger L. Prosst Proctological Institute Stuttgart, Stuttgart, Germany
Pierluigi Puca Dipartimento di Medicina e chirurgia traslazionale, CEMAD –
UOC di Medicina Interna e Gastroenterologia Fondazione PoliclinicoA. GemelliIRCCS, Rome, Italy
Università Cattolica del Sacro Cuore, Rome, Italy