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Файл:Ординатура / Хирургия / Библиотека им академика М.И. Перельмана / Книга_927_Библиотеки_им_академика_М_И_Перельмана.pdf
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- •Contributors
- •Acknowledgments
- •Contents
- •Inferior Mesenteric Artery
- •Collateral Circulation
- •VENOUS DRAINAGE
- •Superior Mesenteric Vein
- •Inferior Mesenteric Vein
- •LYMPHATIC DRAINAGE
- •INNERVATION
- •COLON AND RECTUM PHYSIOLOGY
- •Colonic Physiology
- •Absorption and Secretion
- •Digestion
- •Propulsion and Storage
- •ANAL CANAL ANATOMY
- •Lining
- •Muscles of the Anorectal Region
- •Perineal Body
- •Pelvic Floor Muscles
- •Innervation of the Anus
- •Motor Innervation
- •Sensory Innervation
- •Arterial Supply of the Anus
- •Lymphatic Drainage of the Anus
- •Venous Drainage of the Anus
- •ANAL CANAL PHYSIOLOGY
- •Mechanisms of Continence
- •Defecation
- •Physiologic Testing
- •Anal Manometry
- •Defecography by Fluoroscopy or Magnetic Resonance Imaging
- •Balloon Expulsion Test
- •Colon
- •Saline Continence Test
- •Rectal Compliance
- •Electromyography
- •Nerve Stimulation Techniques
- •Course and Peritoneal Coverings
- •Rectum
- •Peritoneal Relations and Fascial Attachments
- •ARTERIAL SUPPLY
- •Superior Mesenteric Artery
- •Suggested Reading
- •EXTERNAL HEMORRHOIDS
- •CLINICAL EVALUATION
- •NONEXCISIONAL OPTIONS
- •Medical Management
- •Sclerotherapy
- •Energy-Based Destruction
- •Hemorrhoidal Ligation with Rubber Bands
- •EXCISIONAL HEMORRHOIDECTOMY
- •Instrumentation for Excisional Hemmorrhoidectomy
- •PROCEDURE FOR PROLAPSING HEMORRHOIDS (STAPLED HEMMORHOIDOPEXY)
- •DOPPLER-GUIDED HEMORRHOIDAL DEARTERIALIZATION
- •POSTOPERATIVE MANAGEMENT AFTER HEMORRHOID SURGERY
- •CONCLUSION
- •Suggested Reading
- •INTRODUCTION
- •DIAGNOSIS
- •PATHOPHYSIOLOGY
- •High-Pressure Chronic Anal Fissure
- •Low- and Normal-Pressure Chronic Anal Fissure
- •MANAGEMENT
- •Topical Creams
- •Botulinum Toxin
- •Fissurectomy
- •Cutaneous Advancement Flap
- •Lateral Internal Sphincterotomy
- •Surgical Technique
- •Risk of Incontinence
- •Tailored Sphincterotomy
- •SUMMARY: CHOICE OF TREATMENT
- •Suggested Reading
- •CLASSIFICATION
- •PRESENTATION
- •DIAGNOSIS AND EVALUATION
- •Preparation and Examination
- •TREATMENT
- •INTERSPHINCTERIC ANAL FISTULA
- •Clinical Findings
- •TREATMENT
- •Incontinence Risk
- •TRANSSPHINCTERIC ANAL FISTULA
- •Clinical Findings
- •Treatment
- •Cutting Seton
- •Sphincter-Preserving Techniques
- •LIFT
- •ADVANCEMENT FLAP
- •PARTIAL FISTULOTOMY
- •SUPRASPHINCTERIC ANAL FISTULA
- •Fistula Plugs
- •EXTRASPHINCTERIC ANAL FISTULA
- •SPECIAL SITUATIONS
- •Crohn Disease
- •Deep Postanal Space Abscess with a Horseshoe Fistula
- •SUMMARY
- •Suggested Reading
- •DEFINITION
- •CAUSES
- •HISTORY AND PHYSICAL EXAMINATION
- •SURGICAL ANATOMY
- •ETIOLOGY
- •NATURAL HISTORY OF THE DISEASE AND SPREAD PATHWAYS
- •CLINICAL FEATURES
- •Perianal Abscess
- •Ischiorectal Abscess
- •Intersphincteric Abscess
- •Supralevator Abscess
- •Deep Postanal Abscess
- •Submucosal Abscess
- •DIAGNOSIS
- •Treatment of Anorectal Abscesses
- •Large Abscesses
- •Searching for a Fistula
- •Ischiorectal Abscess
- •Intersphincteric Abscesses
- •Supralevator Abscess
- •Submucosal Abscess
- •Role of Antibiotics and Biopsy
- •Postoperative Care
- •Complications
- •RECURRENCE AND THE DEVELOPMENT OF FISTULA IN ANO
- •Suggested Reading
- •INTRODUCTION
- •ETIOLOGY
- •TREATMENT OPTIONS
- •Medical
- •Nonsurgical Closure
- •Fistula Plug
- •Fibrin Glue
- •Surgical Closure
- •Anal Approach
- •Rectal Advancement Flap
- •Advancement Sleeve Flap
- •Turnbull-Cutait Anastomosis
- •Transvaginal Approach
- •Perineal Approach
- •Ligation of the Intersphincteric Fistula Tract
- •Episioproctotomy
- •Tissue Interposition
- •SPECIAL CONSIDERATIONS
- •Use of a Stoma
- •Postoperative Care
- •Sexual Function/Vaginal Dryness
- •Recurrence
- •CONCLUSION
- •Suggested Reading
- •ETIOLOGY
- •PRESENTATION
- •TREATMENT
- •Asymptomatic Pilonidal Sinus
- •Pilonidal Abscess
- •Chronic Pilonidal Sinus
- •NONOPERATIVE MANAGEMENT
- •Hair Removal
- •SURGERY
- •Lateral Drainage, Curettage, and Midline Pit Excision
- •Local Excision and Healing by Secondary Intention
- •FLAP-BASED PROCEDURES
- •Karydakis Procedure
- •Cleft Lift Procedure
- •Rhomboid Excision and Flap Repair
- •Cavity Drainage
- •CONCLUSION
- •Suggested Reading
- •ETIOLOGY
- •CLINICAL PRESENTATION AND EVALUATION
- •ANTIBIOTIC TREATMENT
- •NONANTIBIOTIC TREATMENT
- •SURGICAL TREATMENT
- •SUMMARY
- •Suggested Reading
- •INTRODUCTION
- •ETIOLOGY
- •PRIMARY CAUSES OF PRURITUS ANI
- •Pathophysiology
- •HISTORY
- •EXAMINATION
- •TREATMENT
- •SECONDARY PRURITUS ANI TREATMENT
- •Anorectal Conditions
- •Infections
- •Dermatologic Conditions
- •Neoplastic Causes
- •Systemic Disease
- •REFRACTORY OR PERSISTENT PRURITUS ANI
- •SUMMARY
- •Suggested Reading
- •INTRODUCTION
- •DEFINITION
- •CLASSIFICATION OF ANAL STENOSIS
- •Cause
- •Spasm
- •Postoperative Scarring
- •Stenosis Due to Chronic Diarrhea
- •Age-Related Stenosis
- •SYMPTOMS
- •Examination Findings
- •PREVENTION OF POSTOPERATIVE ANAL STENOSIS
- •TREATMENT
- •Nonoperative Management
- •Anal Dilation
- •Surgical Management
- •Anoplasty
- •Postoperative Complications of Anoplasty
- •Suggested Reading
- •BACKGROUND AND EPIDEMIOLOGY
- •PRESENTATION OF DISEASE AND DIAGNOSIS
- •TREATMENT OF ANAL CONDYLOMA
- •Medical Therapies
- •Trichloracetic and Bichloracetic Acid
- •Imiquimod
- •Other Medical Treatments
- •Ablative Therapies
- •Cryotherapy
- •Surgical Excision/Fulguration
- •Laser
- •Recurrent Disease
- •Treatment Algorithm
- •CONCLUSION
- •Suggested Reading
- •BACTERIAL INFECTIONS
- •Gonorrhea
- •Preferred Clinical Approach
- •Chlamydia trachomatis and Lymphogranuloma venereum
- •Preferred Clinical Approach
- •Chancroid
- •Preferred Clinical Approach
- •Granuloma Inguinale
- •Preferred Clinical Approach
- •Syphilis (“The Great Masquerader”)
- •Preferred Clinical Approach
- •VIRAL INFECTIONS
- •Herpes Simplex Virus
- •Preferred Clinical Approach
- •Condylomata Acuminata
- •Clinical Manifestations
- •Treatment
- •Preferred Clinical Approach
- •Electrocautery
- •OTHER DISORDERS
- •Suggested Reading
- •INTRODUCTION
- •HIGH-GRADE SQUAMOUS INTRAEPITHELIAL LESION (FORMERLY BOWEN DISEASE)
- •Management
- •PERIANAL PAGET DISEASE
- •Management
- •Suggested Reading
- •INTRODUCTION
- •EPIDEMIOLOGY AND RISK FACTORS
- •PATHOPHYSIOLOGY
- •CLINICAL PRESENTATION AND DIAGNOSIS
- •SURGERY
- •Management of the Primary Tumor
- •Management of Lymph Nodes
- •SURVIVAL
- •BASAL CELL CANCER OF THE PERIANAL REGION
- •Suggested Reading
- •INTRODUCTION
- •ANATOMIC CONSIDERATIONS
- •EPIDEMIOLOGY
- •SQUAMOUS CELL CARCINOMA OF THE ANAL CANAL
- •Surveillance
- •Local Excision
- •Inguinal Lymph Node Management
- •Extrapelvic Metastases
- •PERIANAL SQUAMOUS CELL CARCINOMA
- •ANAL CANCER AND HIV INFECTION
- •Suggested Reading
- •A GENERAL APPROACH
- •CHRONIC PROCTALGIA
- •LEVATOR ANI SYNDROME
- •Diagnosis
- •Treatment
- •PROCTALGIA FUGAX
- •COCCYGODYNIA
- •CONCLUSION
- •Selected Readings
- •DESCRIPTION OF DEFECTS
- •Perineal Fistula
- •Rectal Atresia
- •Vestibular Fistula
- •Imperforate Anus without Fistula
- •Rectourethral Bulbar Fistula
- •Rectourethral Prostatic Fistula
- •Cloaca
- •Recto-Bladder-Neck Fistula
- •NEONATAL MANAGEMENT
- •Anoplasty
- •Management of Functional Sequelae
- •ETIOLOGY, PATHOPHYSIOLOGY, AND INCIDENCE
- •DIAGNOSIS
- •Anorectal Manometry
- •Rectal Biopsy
- •Resuscitation
- •Main Repair
- •Duhamel Procedure
- •Soave Procedure
- •Dehiscence and Retraction
- •Constipation
- •ASSESSMENT
- •Medical Management
- •Postanal Repair
- •Anal Encirclement
- •Muscle Transposition
- •Continence Enemas
- •Stem Cells, Bulking Agents, and Other Techniques
- •Fecal Diversion
- •CONCLUSIONS
- •DEFINITION
- •ETIOLOGY
- •BENIGN RECTAL STRICTURES
- •Medical Treatment
- •Digital Evacuation
- •Enemas and Colonic Lavage
- •Oral Solutions
- •Stool Softeners
- •Laxatives
- •Endoscopic Disimpaction
- •SURGERY
- •Acute
- •PREVENTION
- •CONCLUSION
- •PATHOPHYSIOLOGY
- •Recommendations
- •Nonoperative Management
- •CONCLUSIONS
- •DEFINITION
- •DIAGNOSIS
- •Transanal Repairs
- •Transvaginal Repairs
- •EPIDEMIOLOGY
- •Location of the Foreign Body
- •Intraperitoneal or Extraperitoneal
- •Tailgut Cysts
- •Duplication Cysts
- •Transanal Excision
- •Anterior Resection
- •Physical Examination
- •Locoregional Evaluation
- •Nodal Staging
- •Extramural Venous Invasion
- •Locoregional Imaging Synoptic Reports
- •Distant Metastatic Evaluation
- •RADIATION-RELATED TOXICITIES
- •Boosting the Dose
- •HIGH-DOSE-RATE ENDORECTAL BRACHYTHERAPY
- •Total Mesorectal Excision
- •Ligation of the Inferior Mesenteric Artery
- •Distal Resection Margins
- •Drainage
- •Positioning and Equipment
- •Trocar Placement
- •Exposure of the Operating Field
- •Division of the Vessels and Splenic Flexure Mobilization
- •Mobilization and Division of the Rectum
- •Exteriorization of the Specimen
- •Creation of the Anastomosis
- •Abdominoperineal Resection
- •Closure of the Anal Opening
- •Mobilization of the Rectum
- •Proximal Division of the Left Colon
- •Perineal Dissection and Exteriorization
- •Closure of Pelvic Wound and Trocar Incisions and Creation of the Colostomy
- •INITIAL SELECTION
- •Patient Preparation
- •Transanal Excision
- •MANAGEMENT OF THE SPECIMEN
- •Salvage Resection after Local Excision
- •Axial Recurrences
- •Anterior Recurrences
- •Posterior Recurrences
- •Lateral Recurrences
- •THERAPY
- •Patient Selection
- •Procedures
- •Complications
- •PREVENTION
- •SUMMARY
- •RISK ASSESSMENT
- •PREOPERATIVE PULMONARY ASSESSMENT AND MANAGEMENT
- •MANAGEMENT OF PATIENTS RECEIVING ANTITHROMBOTIC THERAPY
- •Diagnosis
- •Diet
- •5-Aminosalycilic Acid
- •Mild to Moderate Ulcerative Colitis
- •Proctitis and Left-Sided Ulcerative Colitis
- •Left-Sided Disease
- •Extensive Disease
- •Lack of Response to 5-Aminosalycilic Acid
- •Oral Budesonide
- •Corticosteroids
- •Severe Ulcerative Colitis
- •Cyclosporine
- •Azathioprine and 6-Mercaptopurine
- •Biologic Agents
- •Adalimumab
- •Golimumab
- •How to Choose an Anti-TNF-α Agent
- •Complications
- •What to Do Before Starting Anti-TNF-α Therapy
- •What to Do Once Treatment with an Anti-TNF-α Agent Is Started
- •Antiadhesion Molecules
- •Alternative Therapies
- •Nicotine
- •Clinical Scenarios
- •Quiescent Disease
- •Fulminant or Toxic Colitis
- •Flexible Sigmoidoscopy with Biopsies
- •Deep Vein Thrombosis Prophylaxis
- •Evaluate for Tuberculosis and Hepatitis B
- •Avoid Narcotics and Antidiarrheal Medications
- •Do Not Use Antibiotics
- •Diet as Tolerated
- •Perform Close Observation and Consult Colorectal Surgery upon Admission
- •Vaccinations
- •Pregnancy
- •Cancer Risk
- •Drug-Induced Colitis
- •Proctectomy Surgical Technique
- •Staging the Procedure
- •Technique of Creation of an Ileoanal J Pouch
- •Problems with Reach of the Pouch
- •Complications after Ileal Pouch–Anal Anastomosis
- •Overall Quality of Life
- •Function of the Pouch
- •Pouchitis
- •Pouch Failure
- •Salvage of the Failed Pelvic Pouch
- •PRESENTATION
- •EVALUATION
- •Surgical Options
- •CONCLUSION
- •Pelvis Sepsis and Anastomotic Leak
- •Postoperative Bleeding from the Pouch
- •Pouch-Perineal and Pouch-Vaginal Fistulae
- •Outlet Dysfunction
- •POUCHITIS
- •Genetic Factors
- •CONCLUSIONS
- •Late Complications
- •Valve Slippage
- •Parastomal Hernia
- •Crohn Disease
- •Pouchitis
- •Valve Stenosis
- •Pouch Excision
- •CONCLUSIONS
- •Crohn Disease
- •Radiation
- •PREVENTION
- •Reconstruction of the Perineum with a Flap
- •5-Aminosalicylates
- •Antibiotics
- •Biologic Agents
- •SMOKING
- •NUTRITION
- •Disease of the Colon and Rectum
- •SPECIAL SITUATIONS
- •Medications
- •Abscess
- •Fistula
- •Neoplasia
- •OUTCOME
- •Anal Sepsis
- •Stenosis
- •CONCLUSION
- •CONCLUSION
- •CYTOMEGALOVIRUS COLITIS
- •KAPOSI SARCOMA
- •COMPLICATED DIVERTICULITIS
- •INTRODUCTION
- •ETIOLOGY
- •Right-Sided Obstruction
- •Left-Sided Obstruction
- •Self-Expanding Metallic Stents
- •COLONIC VOLVULUS
- •Signs and Symptoms
- •Diagnostic Imaging
- •Signs and Symptoms
- •Diagnostic Imaging
- •TRANSVERSE COLON VOLVULUS
- •Pathophysiology
- •Diagnostic Imaging
- •Signs and Symptoms
- •Treatment
- •EPIDEMIOLOGY
- •ETIOLOGY
- •Initial Management
- •Pharmacologic Management
- •BIOLOGY
- •MARGIN
- •NODES
- •COMORBIDITIES
- •SUMMARY
- •SCREENING FOR COLORECTAL CANCER
- •Flexible Sigmoidoscopy
- •Stool DNA
- •Surveillance Colonoscopy after Endoscopic Resection of a Malignant Polyp
- •Surveillance Colonoscopy in Patients with Colorectal Cancer
- •Surveillance Colonoscopy in Patients with a Family History of Colorectal Cancer or Adenomatous Polyps
- •CONCLUSION
- •INTRODUCTION
- •GROWTH CONTROL
- •DNA REPAIR
- •COMPLEXITY
- •REGISTRIES
- •DEFINITIONS
- •Genotype/Phenotype
- •Surgical Options for the Large Bowel
- •Extracolonic Manifestations
- •Hepatoblastoma
- •Surveillance
- •The IRA
- •The IPAA
- •Oligopolyposis/Attenuated Familial Adenomatous Polyposis
- •PTEN Tumor Hamartoma Syndrome
- •INTRODUCTION
- •BIOLOGY
- •EPIDEMIOLOGY
- •GENETICS AND DESMOID RISK
- •DESMOID SEVERITY: A STAGING SYSTEM
- •MANAGEMENT
- •Setting Expectations
- •A Philosophy of Care
- •Extra-abdominal Desmoid Tumors
- •Abdominal Wall Tumors
- •Intra-abdominal Desmoid Disease
- •Workup
- •Medical Treatment
- •Role of Surgery
- •Complications of Desmoid Disease
- •Small Bowel Obstruction
- •Ureteric Obstruction
- •Abscess/Enterocutaneous Fistula
- •Superior Mesenteric Artery Aneurysm
- •Points about Operating on Persons with Desmoid Disease
- •SUMMARY AND GENERAL COMMENTS ABOUT THE EFFECT OF DESMOID DISEASE ON SURGICAL STRATEGY IN FAMILIAL ADENOMATOUS POLYPOSIS
- •Suggested Reading
- •INTRODUCTION
- •HISTORICAL PERSPECTIVE AND CLARIFICATION OF TERMS
- •GENETIC AND MOLECULAR CAUSE OF LYNCH SYNDROME
- •HISTOLOGIC FEATURES OF LYNCH TUMORS
- •DIAGNOSING LYNCH SYNDROME
- •Clinical Criteria
- •Models
- •Tumor Testing
- •GENETIC COUNSELING AND TESTING
- •CLINICAL MANIFESTATIONS AND MANAGEMENT
- •COLORECTAL CANCER RISK MANAGEMENT
- •Surveillance Colonoscopy and Polypectomy
- •Chemoprevention
- •Surgery
- •Colectomy in the Absence of Cancer
- •Treatment of Colon Cancer
- •Rectal Cancer in Persons with Lynch Syndrome
- •RISK MANAGEMENT OF EXTRACOLONIC MANIFESTIONS
- •Endometrial and Ovarian Cancer
- •Upper Gastrointestinal Tract
- •Urinary Tract
- •Skin Neoplasms
- •Other Cancers
- •CLINICAL VARIATIONS OF HNPCC AND LYNCH SYNDROME
- •Familial Colorectal Cancer Type X
- •Tumor Lynch
- •SUMMARY
- •Suggested Reading
- •INTRODUCTION
- •PATHOLOGY OF APPENDICEAL MALIGNANT TUMORS
- •Carcinoid Tumors
- •Epithelial (Noncarcinoid) Tumors of the Appendix
- •Mucinous Adenoma and Adenocarcinoma
- •Nonmucinous Adenocarcinoma
- •DIAGNOSIS OF APPENDICEAL MALIGNANT TUMORS
- •Carcinoid
- •Adenocarcinoma and Mucinous Adenocarcinoma
- •Pseudomyxoma Peritonei Syndrome
- •Carcinoid Tumors
- •Appendiceal Adenocarcinoma
- •Management of Appendiceal Neoplasms with Peritoneal Dissemination
- •Perioperative Chemotherapy
- •Serial Debulking
- •CYTOREDUCTIVE SURGERY AND PERIOPERATIVE CHEMOTHERAPY
- •Survival by Completeness of Cytoreduction
- •Survival by Histologic Assessment
- •Survival by Prior Surgical Score
- •Morbidity and Mortality Rates
- •Peritonectomy
- •Perioperative Chemotherapy
- •Suggested Reading
- •INTRODUCTION
- •EPIDEMIOLOGY
- •Prognostic Factors
- •PREOPERATIVE EVALUATION
- •PREOPERATIVE PREPARATION
- •OPERATIVE PRINCIPLES AND TECHNIQUES
- •Exploration
- •Surgical Treatment of Right Colon Cancer
- •Surgical Treatment of Transverse Colon Cancer
- •Surgical Treatment of Splenic Flexure and Descending Colon Cancer
- •Surgical Treatment of Sigmoid Colon Cancer
- •LAPAROSCOPIC COLECTOMY
- •SPECIAL CONSIDERATIONS
- •Obstruction and Perforation
- •Prophylactic Oophorectomy
- •POSTOPERATIVE SURVEILLANCE
- •SUMMARY
- •Suggested Readings
- •INTRODUCTION
- •CHEMOTHERAPY
- •5-Fu
- •Capecitabine
- •Irinotecan
- •Oxaliplatin
- •MAINTENANCE CHEMOTHERAPY
- •BIOLOGIC AGENTS
- •FIRST-LINE TARGETED OPTIONS
- •THIRD- AND FOURTH-LINE OPTIONS
- •OLIGOMETASTATIC DISEASE
- •ROLE OF RESECTION OF PRIMARY LESION
- •IMMUNOTHERAPY
- •CONCLUSIONS
- •Suggested Reading
- •INTRODUCTION
- •DIAGNOSIS AND PREOPERATIVE WORKUP
- •Imaging
- •Serologic and Molecular Markers
- •Histology
- •Needle Biopsy
- •Multidisciplinary Planning
- •STAGING AND PROGNOSIS
- •PROGNOSTIC SCORES
- •TREATMENT
- •Chemotherapy
- •Neoadjuvant Chemotherapy for Resectable Liver Disease
- •Neoadjuvant Chemotherapy for Unresectable Liver Disease
- •Adjuvant Chemotherapy
- •Hepatic Arterial Infusion
- •Resectability
- •Resectable Liver Disease
- •Synchronous Liver Metastasis
- •Unresectable Liver Disease
- •Repeat Resections for Multiple Liver Metastases
- •Local Ablative Therapy
- •Radiofrequency Ablation
- •Microwave Ablation
- •Cryotherapy
- •Irreversible Electroporation
- •Colorectal Liver Metastases with Extrahepatic Spread
- •Lung
- •Peritoneal
- •Lymph Node Involvement
- •Inferior Vena Cava
- •Recurrence
- •SURVEILLANCE
- •CONCLUSION
- •Suggested Readings
- •INTRODUCTION
- •INDICATIONS FOR RESECTION OF COLORECTAL METASTASES
- •OUTCOMES OF PATIENTS UNDERGOING RESECTION AND PROGNOSTIC FACTORS
- •LUNG AND LIVER METASTASIS
- •SURGICAL APPROACH
- •DEVELOPMENT OF A PROSPECTIVE RANDOMIZED TRIAL: THE PULMONARY METASTASECTOMY IN COLORECTAL CANCER TRIAL
- •CONCLUSION
- •Suggested Reading
- •INTRODUCTION
- •BENIGN NONADENOMATOUS LESIONS OF THE COLON AND RECTUM
- •Benign Lymphoid Hyperplasia
- •Lipomas
- •Treatment
- •CAVERNOUS HEMANGIOMA
- •Characteristic Features
- •Treatment
- •Surgery (Laparotomy/Laparoscopic)
- •LEIOMYOMA AND LEIOMYOSARCOMA
- •Characteristic Features
- •Surgery
- •PRIMARY LYMPHOMA OF THE COLON AND RECTUM
- •SUMMARY
- •Suggested Reading
- •INTRODUCTION
- •ETIOLOGY AND PATHOGENESIS
- •CLASSIFICATION
- •CLINICAL PRESENTATION
- •DIAGNOSIS
- •MANAGEMENT
- •OUTCOME
- •SPECIAL TOPICS
- •Ischemic Colitis after Aortic Surgery
- •Colonic Ischemia after Cardiopulmonary Bypass
- •Ischemic Colitis Associated with Colon Carcinoma and Obstructing Colon Lesions
- •Total Colonic Ischemia
- •Ischemic Proctosigmoiditis
- •CONCLUSION
- •Suggested Readings
- •INTRODUCTION
- •ETIOLOGY
- •DIAGNOSIS
- •Physical Examination
- •Imaging
- •Diagnostic Peritoneal Lavage
- •Laparoscopy
- •TREATMENT
- •Colon Injuries
- •Damage Control
- •Rectal Injuries
- •Overview
- •Diversion
- •Direct Repair
- •Drainage
- •Distal Washout
- •Rectal Foreign Bodies
- •Suggested Reading
- •INTRODUCTION
- •PAIN
- •INFERTILITY
- •DIAGNOSIS
- •Physical Examination
- •Endoscopy
- •Imaging
- •SURGICAL MANAGEMENT
- •Results after Surgical Therapy
- •Combined Medical and Surgical Therapy
- •CONCLUSION
- •Suggested Reading
- •INTRODUCTION
- •ETIOLOGY
- •CLASSIFICATION
- •HISTOLOGY AND GROSS PATHOLOGY
- •SYMPTOMS
- •DIAGNOSIS
- •TREATMENT
- •Suggested Readings
- •INTRODUCTION
- •CAUSES
- •CLASSIFYING CONSTIPATION
- •ASSESSMENT
- •History
- •Physical Examination
- •INVESTIGATIONS
- •TREATMENT
- •Medical
- •Newer Promotility Agents
- •Biofeedback for Pelvic Floor Dyssynergia
- •Change in Position of Defecation
- •Surgery
- •Outlet Obstruction Constipation
- •Suggested Reading
- •EXTENT OF THE PROBLEM
- •CLINICAL PRESENTATION
- •IMAGING
- •MRI and Ultrasound
- •MANAGEMENT OF SMALL BOWEL OBSTRUCTION
- •Nonadhesive Obstruction
- •Hernias
- •Crohn Disease
- •Malignancy
- •Intussusception
- •Gallstone Ileus
- •Bariatric Patient
- •Surgical Technique
- •Adhesive Obstruction
- •Hernias
- •Malignancy
- •Intussusception
- •Gallstone Ileus
- •The Bariatric Patient
- •Laparoscopic versus Open Lysis of Adhesions
- •Early Postoperative Bowel Obstruction
- •Prevention of Adhesions
- •SUMMARY
- •Suggested Reading
- •INTRODUCTION
- •DIETARY MANAGEMENT OF SHORT BOWEL SYNDROME
- •PHARMACOLOGIC TREATMENT OF SHORT BOWEL SYNDROME
- •PARENTERAL AND ENTERAL NUTRITION
- •HORMONAL TREATMENT FOR SHORT BOWEL SYNDROME
- •COMPLICATIONS ASSOCIATED WITH SHORT BOWEL SYNDROME
- •CONCLUSION
- •Suggested Reading
- •INTRODUCTION
- •GUT ADAPTATION
- •MEDICAL MANAGEMENT
- •SURGICAL REHABILITATION
- •Strategy
- •Autologous Reconstruction
- •Intestinal Lengthening
- •INTESTINAL AND MULTIVISCERAL TRANSPLANTATION
- •Types
- •Indications
- •Contraindications
- •Early Referral
- •Transplantation Surgery
- •Postoperative Management
- •Current Global Activities
- •Long-Term Survival
- •Allograft Function
- •Quality of Life
- •New Insights
- •SUMMARY
- •Suggested Reading
- •INTRODUCTION
- •CLINICAL PRESENTATION
- •INVESTIGATIONS IN UPPER GASTROINTESTINAL CROHN DISEASE
- •MEDICAL TREATMENT
- •ENDOSCOPIC TREATMENT
- •SURGERY
- •SUMMARY
- •Suggested Readings
- •INTRODUCTION
- •MEDICAL MANAGEMENT
- •INDICATIONS FOR SURGERY
- •PREOPERATIVE CONSIDERATIONS
- •OPERATIVE APPROACH
- •SURGICAL OPTIONS
- •Bypass
- •Resection
- •Strictureplasty
- •SPECIAL SITUATIONS
- •Medications
- •Abscess
- •Free Perforation
- •Hemorrhage
- •Growth Retardation
- •Fistula
- •Neoplasia
- •Obstruction
- •OUTCOME
- •SUMMARY
- •Selected Reading
- •INTRODUCTION
- •PRESENTATION
- •DIAGNOSIS
- •MANAGEMENT
- •Adenocarcinoma without Metastatic Disease
- •Carcinoid Tumors
- •Lymphomas
- •GIST Tumors
- •CONCLUSION
- •ACKNOWLEDGMENT
- •Suggested Readings
- •DEFINITION
- •INCIDENCE, EPIDEMIOLOGY, AND RESEARCH
- •CLINICAL PRESENTATION
- •DIAGNOSIS
- •CLASSIFICATION
- •SURGICAL TREATMENT
- •Small Intestine
- •Appendix
- •Colon
- •Rectum
- •Locally Advanced and Metastatic Disease
- •Hedinger Syndrome
- •ADJUVANT THERAPY
- •FOLLOW-UP
- •PROGNOSIS
- •Suggested Reading
- •INTRODUCTION
- •PATHOGENESIS
- •GENERAL ASPECTS OF CARE
- •COMPLICATIONS
- •PLAN OF CARE
- •Prevention
- •Stabilization
- •Wound Care
- •Nutritional Support
- •Nasogastric Tubes and Other Drainage Tubes
- •Protection of the Gastric, Duodenal, and Upper Gastrointestinal Tract Mucosa from Ulceration
- •Other Supplements
- •Investigation/Elucidation
- •Therapeutic Decisions
- •Will It Close?
- •The Decision to Operate
- •Timing of Surgery
- •Surgery
- •Choice of Incision
- •The Operation Itself
- •Anastomosis
- •Abdominal Wound Closure
- •What Type of Operation Should One Undertake?
- •Gastrostomy and Feeding Jejunostomy
- •The Healing Phase
- •Fibrin Glue
- •Short Bowel Syndrome
- •PROGNOSIS
- •Suggested Reading
- •INTRODUCTION
- •ACUTE MESENTERIC ISCHEMIA
- •Clinical Presentation
- •Evaluation
- •Treatment
- •SMA Embolus
- •SMA Thrombus
- •Mesenteric Venous Thrombosis
- •Nonocclusive Mesenteric Ischemia
- •Bowel Viability
- •Laparoscopy
- •CHRONIC MESENTERIC ISCHEMIA
- •Presentation
- •Evaluation
- •Operative Treatment
- •Angioplasty
- •CONCLUSION
- •Suggested Readings
- •BACKGROUND
- •PATHOPHYSIOLOGY
- •PREDISPOSING RISK FACTORS
- •GRADING SYSTEMS
- •DIAGNOSTIC WORKUP
- •PREVENTION
- •MANAGEMENT OF RADIATION ENTERITIS
- •Management of Radiation Injury to the Small Bowel
- •Acute Radiation Enteritis
- •Chronic Radiation Enteritis
- •Management of Radiation Injury to the Colon
- •Acute Radiation Colitis
- •Chronic Radiation Colitis
- •Management of Radiation Injury to the Rectum
- •Topical Therapy
- •Hyperbaric Oxygen
- •Medical Therapy
- •Endoscopic Management
- •Surgery
- •CONCLUSION
- •Suggested Readings
- •INTRODUCTION
- •IDENTIFICATION OF THE HIGH-RISK PATIENT
- •MINIMIZING RISK ASSOCIATED WITH EMERGENCY SURGERY
- •MINIMIZING RISK ASSOCIATED WITH CARDIAC DISEASE
- •MINIMIZING RISK ASSOCIATED WITH PULMONARY DISEASE
- •MINIMIZING RISK ASSOCIATED WITH IMMUNOSUPPRESSION
- •Steroids
- •Diabetes
- •Chemoradiotherapy
- •MINIMIZING RISK ASSOCIATED WITH MALNUTRITION
- •MINIMIZING RISK ASSOCIATED WITH HEPATIC DISEASE
- •MINIMIZING RISK ASSOCIATED WITH RENAL DISEASE
- •MINIMIZING RISK IN MORBIDLY OBESE PATIENTS
- •Suggested Reading
- •INTRODUCTION
- •ANATOMIC FACTORS
- •The Ureters
- •Presacral Veins
- •Pelvic Nerves
- •POSTOPERATIVE CHANGES IN THE PELVIS
- •Approach to Reoperative Pelvic Surgery
- •Preoperative Planning
- •Timing
- •Patient Preparation
- •Functional Considerations
- •Intraoperative Conduct
- •Patient Positioning
- •Optimizing Visibility and Exposure
- •Access to the Pelvis
- •Ureter
- •Bladder
- •Rectal Stump
- •Vagina
- •Autonomic Nerves
- •Control of Bleeding
- •Drainage
- •SPECIFIC CLINICAL SITUATIONS
- •Reversal of Hartmann Procedure for Diverticulitis
- •Recurrent Rectal Cancer
- •Redo Ileoanal Pelvic Pouch Procedure
- •SUMMARY
- •Suggested Reading
- •INTRODUCTION
- •NUTRITIONAL ASSESSMENT
- •INDICATIONS FOR NUTRITIONAL SUPPORT
- •General Indications
- •Severe Malnutrition
- •Postoperative Nutrition
- •Colorectal Cancer
- •ESTIMATION OF NUTRIENT REQUIREMENTS
- •Calories
- •Protein
- •PREVENTION
- •Preventive Measures
- •Bowel Preparation
- •Prophylactic Antibiotics
- •Intact Anastomosis
- •Tension-Free Anastomosis
- •Well-Vascularized Anastomosis
- •Consideration for Diversion
- •Appropriate Use of Drains
- •Goal-Directed Hemodynamic Support
- •Evaluation
- •Nonoperative Interventions
- •Operation versus Observation
- •Open Abdomen
- •Return to the Operating Room
- •Suggested Readings
- •INTRODUCTION
- •WHAT DEFINES A LEAK?
- •PRINCIPLES OF MANAGEMENT
- •EARLY DIAGNOSIS
- •IMAGING
- •CRP LEVELS
- •ENDOSCOPY
- •VARIABLES DIRECTING MANAGEMENT
- •Location: Intraperitoneal versus Extraperitoneal
- •Symptoms: Sepsis versus Symptomatic versus Asymptomatic
- •Previously Diverted: Proximal Diverting Ostomy versus Nondiverted
- •LEAK MANAGEMENT TOOLS
- •ENDO-VACUUM ASSISTED CLOSURE
- •ENDOSCOPIC STENTS, CLIPS, AND GLUE
- •DIETARY COMPOSITION AND DELIVERY
- •Hospital-Based Diets
- •Clear Liquid Diet
- •Regular Diet
- •Low-Residue Diet
- •Oral Supplements
- •Liquid Formula Diets
- •Enteral Nutrition
- •Access for EN
- •Early Postoperative Feeding: “Fast Track”
- •Parenteral Nutrition
- •Access for PN
- •Concomitant EN and PN
- •Overfeeding
- •NEW DIRECTIONS
- •Immunonutrition
- •Preoperative Carbohydrate Loading
- •SUMMARY
- •Suggested Reading
- •BACKGROUND
- •TRANSANAL REPAIR TECHNIQUES
- •TURNBULL-CUTAIT PULL THROUGH
- •SUMMARY
- •Suggested Reading
- •INTRODUCTION
- •RISK MANAGEMENT
- •HEMORRHAGE
- •Steps Prior to Colonoscopy
- •Risk Factors for Bleeding
- •Prevention of Bleeding
- •Treatment of Bleeding
- •PERFORATION
- •Causes of Perforation
- •Diagnosis of Perforation
- •Management of Perforation
- •Suggested Readings
- •INTRODUCTION
- •PERTINENT ANATOMY
- •BLEEDING
- •Major Vessel Bleeding
- •Iliac Vessels
- •Minor Vessel Bleeding
- •Presacral Bleeding
- •Pelvic Packing
- •Suture Ligation
- •Thumbtacks
- •Muscle Fragment Welding
- •Bipolar Electrocautery
- •Hemostasis Step-by-Step Technique
- •Hemostatic Agents
- •Mechanical Hemostatic Agents
- •Active Hemostatic Agents
- •Flowable Hemostatic Agents
- •Fibrin Sealants
- •CONCLUSION
- •Selected Reading
- •INTRODUCTION
- •INFECTION
- •URETER
- •BLADDER
- •URETHRA
- •REPRODUCTIVE STRUCTURES
- •NERVES
- •BLOOD VESSELS
- •Suggested Readings
- •INTRODUCTION
- •GENERAL COMPLICATIONS
- •Contraindications
- •Peritoneal Access Complications
- •Pneumoperitoneum Complications
- •Thromboembolic Complications
- •Electrosurgical Complications
- •Positioning Complications
- •Bleeding Complications
- •Contamination
- •Anastomosis Complications
- •Urologic Complications
- •CONCLUSIONS
- •Suggested Reading
- •INTRODUCTION
- •OSTOMY CREATION
- •Preoperative Discussion and Consent
- •Siting the Stoma
- •Creating and Maturing the Stoma
- •End Ileostomy
- •Loop Ileostomy
- •COMPLICATIONS
- •Early Complications
- •Appliance Issues/Skin Irritation
- •Ischemia
- •Stoma Stenosis
- •Retraction
- •Late Complications
- •Parastomal Hernia
- •Prolapse
- •Stricture
- •Peristomal Pyoderma
- •Parastomal Ulcer
- •Abscess and Fistula
- •SUMMARY
- •Suggested Reading
- •PREOPERATIVE PREPARATION
- •Preoperative Counseling
- •Stoma Site Marking
- •POSTOPERATIVE MANAGEMENT
- •SPECIAL CONSIDERATIONS
- •Continent ileostomy
- •WOUND MANAGEMENT
- •POSTDISCHARGE FOLLOW-UP
- •COLOSTOMY IRRIGATION

CONTRIBUTORS
ix
Alok A. Khorana, MD
Professor of Medicine
Cleveland Clinic Lerner College of Medicine
Case Western Reserve University
Sondra and Stephen Hardis Chair in Oncology Research
Vice Chair (Clinical Services and Strategy)
Director GI Malignancies Program
Taussig Cancer Institute
Cleveland Clinic
Cleveland, Ohio
Ravi P. Kiran, MBBS, MS, FRCS (Eng), FRCS (Glas), FACS
Kenneth A. Forde Professor of Surgery
Columbia University Medical Center and Mailman School
of Public Health
Chief and Program Director
Division of Colorectal Surgery
Director
Center for Innovation and Outcomes Research
New York-Presbyterian Hospital/Columbia University Medical
Center
New York, New York
Walter A. Koltun, MD, FACS, FASCRS
Professor of Surgery
Peter and Marshia Carlino Chair in IBD
Chief, Division of Colon and Rectal Surgery
Director, Inammatory Bowel Disease Center
Milton S. Hershey Medical Center
Pennsylvania State College of Medicine
Hershey, Pennsylvania
Rodney J. Kratz, MD, FASCRS
Attending Surgeon
Swedish Colon and Rectal Clinic
Seattle, Washington
Ajit Krishnaney, MD
Sta, Center for Spine Health
Department of Neurosurgery
Neurological Institute
Cleveland Clinic
Cleveland, Ohio
Nicholas La Gamma, MD
Assistant Professor of Surgery
Hofstra Northwell School of Medicine
Hempstead, New York
Sergio Larach, MD, FACS
Associate Professor of Colon and Rectal Surgery
University of Florida
Gainesville, Florida
Philip A. Linden, MD
Chief, Division of oracic and Esophageal Surgery
University Hospitals Case Medical Center
Associate Professor
Case Western Reserve University School of Medicine
Cleveland, Ohio
Ian Lindsey, MBBS, FRACS
Department of Colorectal Surgery
John Radclie Hospital
Oxford, United Kingdom
Walter E. Longo, MD, FACS, FASCRS
Department of Surgery
Yale University School of Medicine
New Haven, Connecticut
Kim C. Lu, MD, FASCRS
Associate Professor of Surgery
Division of Gastrointestinal and General Surgery
Department of Surgery
Oregon Health and Science University
Portland, Oregon
Kirk A. Ludwig, MD
e Vernon O. Underwood Professor
Professor of Surgery
Chief, Division of Colorectal Surgery
Department of Surgery
Medical College of Wisconsin
Milwaukee, Wisconsin
Carole Macaron, MD
Section of Gastroenterology
Department of Veterans Aairs
Louis Stokes Cleveland Medical Center
Cleveland, Ohio
Nikita Neha Machado, MD
University Hospitals Case Medical Center
Cleveland, Ohio
Mark L. Manwaring, MD
Assistant Professor of Surgery
East Carolina University
Greenville, North Carolina
David A. Margolin, MD
Ochsner Clinic Foundation
New Orleans, Louisiana
John H. Marks, MD, FACS, FASCRS
Chief of Colorectal Surgery
Main Line Health Systems
Director
Minimally Invasive Colorectal Surgery and Rectal Cancer
Management Fellowship
Lankenau Medical Center
Professor
Lankenau Institute of Medical Research
e Lankenau Hospital
Main Line Health System
Wynnewood, Pennsylvania
Beatriz Martin-Perez, MD
Clinical Research Fellow
Colon and Rectal Surgery Fellowship
Florida Hospital
Orlando, Florida
Joseph Martz, MD, FACS, FASCRS
Chief, Division of Colon and Rectal Surgery
Mount Sinai Beth Israel,
Associate Professor of Surgery
Icahn School of Medicine at Mount Sinai
New York, New York

x
CONTRIBUTORS
Michael H. McCafferty, MD
Professor
Department of Surgery
University of Louisville School of Medicine
Louisville, Kentucky
Robin S. McLeod, MD, FRCSC, FACS
Professor
Departments of Surgery and Health Policy, Management, and
Evaluation
University of Toronto
Toronto, Ontario, Canada
David S. Medich, MD
Associate Professor of Surgery
Chief, Section of Colon and Rectal Surgery
University of Pittsburgh School of Medicine
Pittsburgh, Pennsylvania
Kurt Melstrom, MD, FACS, FASCRS
Assistant Professor of Surgery
City of Hope
Duarte, California
Victor L. Modesto, MD, FACS, FASCRS
Orlando VA Medical Center
Clinical Assistant Professor of Surgery
University of Central Florida College of Medicine
Orlando, Florida,
Clinical Adjunct Assistant Professor of Surgery
F. Edward Hebert School of Medicine
Uniformed Services University of the Health Sciences
Bethesda, Maryland
Graham L. Newstead, AM, MB BS, FRACS, FRCS(Eng),
FACS Hon FASCRS, Hon FRSM, Hon FACP (GB&I)
Conjoint Associate Professor
University of New South Wales
Head, Colorectal Surgery
Prince of Wales Private Hospital
Sydney, Australia
Tamim Niazi, MD, FRCP
Jewish General Hospital
McGill University
Montreal, Quebec, Canada
Pasha J. Nisar, MA, MBBChir, DM, FRCS (Gen Surg)
Department of Colorectal Surgery
St. Peter’s Hospital
Chertsey, United Kingdom
Marcus S. Noel, MD
Assistant Professor of Medicine
Wilmot Cancer Institute
University of Rochester
Rochester, New York
Joseph R. Notaro, MD, FACS, FASCRS
Clinical Assistant Professor Surgery
Robert Wood Johnson University Hospital
New Brunswick, New Jersey
David P. O’Brien, MD, FASCRS
Gastrointestinal and Minimally Invasive Surgery Division
e Oregon Clinic
Portland, Oregon
Drogo K. Montague, MD
Center for Genitourinary Reconstruction
Department of Urology
Glickman Urological and Kidney Institute
Professor of Surgery
Cleveland Clinic Lerner College of Medicine
Cleveland, Ohio
Grace A. Montenegro, MD
Minimally Invasive Colon and Rectal Surgery Fellow
Lankenau Medical Center
Wynnewood, Pennsylvania
Harvey G. Moore, MD, FACS, FASCRS
Assistant Professor of Surgery
Section of Colon and Rectal Surgery
Division of Advanced Oncology and Gastrointestinal Surgery
Duke University School of Medicine
Durham, North Carolina
Jesse Moore, MD, FACS
Assistant Professor of Surgery
University of Vermont Medical Center
University of Vermont College of Medicine
Burlington, Vermont
Mark Muhlmann, MBBS (hons), FRACS
Conjoint Lecturer
University of New South Wales
Sydney, Australia
P. Ronan O’Connell, MD, FRCSI, FRCS(Glas), FRCS(Edin)
Professor
Section of Surgery and Surgical Specialties
School of Medicine
University College Dublin
Dublin, Ireland
Guy R. Orangio, MD, FACS, FASCRS
Associate Professor of Surgery
Chief, Section of Colon and Rectal Surgery
Department of Surgery
Louisiana State University School of Medicine
New Orleans, Louisiana
In Ja Park, MD, PhD
Associate Professor
Surgery, Division of Colon and Rectal Surgery
University of Ulsan College of Medicine and Asan Medical Center
Seoul, Korea
Alberto Peña, MD
Professor of Surgery
University of Colorado
Director
International Center for Colorectal Care
Children’s Hospital Colorado
Aurora, Colorado
Jason Penzer, MD, FACS
Attending Surgeon
Northwell Lenox Hill Hospital
Clinical Assistant Professor of Surgery
New York Medical College
New York, New York

CONTRIBUTORS
xi
Clayton C. Petro, MD
General Surgery Research Scholar
Case Comprehensive Hernia Center
University Hospitals Case Medical Center
Cleveland, Ohio
Danielle M. Pickham, MD
General and Colorectal Surgeon
Kaiser Permanente San Jose Medical Center
San Jose, California
John Procaccino, MD, FACS, FASCRS
Assistant Professor of Surgery
Hofstra Northwell School of Medicine
Hempstead, New York
Siraj Rajaratnam, MBChB, FRACS
Colorectal Unit
North Shore Hospital
Auckland, New Zealand
Vikram Reddy, MD, PhD, FACS, FASCRS
Department of Surgery
Colon and Rectal Surgery
Yale University School of Medicine
New Haven, Connecticut
Jonathan Rice, MD, PhD
Senior Resident in Surgery
University of Louisville
Louisville, Kentucky
Peter M. Sagar, MB ChB, FRCS, DM
Consultant Colorectal Surgeon
St. James’s University Hospital
Leeds, United Kingdom
Javier Salgado Pogacnik, MD
Assistant Professor of Surgery
Department of Colon and Rectal Surgery
University of Pittsburgh Medical Center
Pittsburgh, Pennsylvania
Dana R. Sands, MD, FACS, FASCRS
Sta Surgeon
Director, Colorectal Physiology Center
Department of Colorectal Surgery
Cleveland Clinic Florida
Weston, Florida
William Sangster, MD
General Surgery Resident
Department of Surgery
Pennsylvania State University
Hershey Medical Center
Hershey, Pennsylvania
Anthony J. Senagore, MD, MS, MBA
Professor
Chief of Gastrointestinal and Oncologic Surgery
Department of Surgery
University of Texas–Medical Branch at Galveston
Galveston, Texas
Timothy J. Ridolfi, MD
e Vernon O. Underwood Professor
Professor of Surgery
Chief, Division of Colorectal Surgery
Department of Surgery
Medical College of Wisconsin
Milwaukee, Wisconsin
John L. Rombeau, MD, FACS, FASCRS
Emeritus Professor of Surgery
Perelman School of Medicine
University of Pennsylvania
Philadelphia, Pennsylvania
Michael J. Rosen, MD, FACS
Professor of Surgery
Lerner College of Medicine
Cleveland Clinic Foundation
Cleveland, Ohio
Andrew J. Russ, MD
University Colon and Rectal Surgery
Department of Surgery
University of Tennessee Graduate School of Medicine
Knoxville, Tennessee
Theodore J. Saclarides, MD
Professor of Surgery
Rush Medical College
Head, Section of Colon and Rectal Surgery
Rush University Medical Center
Chicago, Illinois
Skandan Shanmugan, MD
Assistant Professor
Department of Surgery
Division of Colon and Rectal Surgery
University of Pennsylvania
Philadelphia, Pennsylvania
Abdullah Shatnawei, MD
Center for Gut Rehabilitation and Transplantation
Transplant Center
Cleveland Clinic
Cleveland, Ohio
Bo Shen, MD
Professor of Medicine and the Ed and Joey Story Chair
Center for Inammatory Bowel Diseases
Cleveland Clinic Foundation
Cleveland, Ohio
Christopher T. Siegel, MD, PhD, FACS
Schulak Endowed Director of the Transplant Institute
University Hospitals Case Medical Center
Surgical Director, Liver Center of Excellence
Digestive Health Institute
Chief, Division of Hepatobiliary and Transplant Surgery
Associate Professor of Surgery
Case Western Reserve University
Cleveland, Ohio
Tim Slack, BSc, MBBS, FRACS
Senior Lecturer
University of Queensland
Queensland, Australia

xii
CONTRIBUTORS
Nathan Smallwood, MD
Research Fellow
Department of Surgery
Baylor University Medical Center
Dallas, Texas
Michael J. Snyder, MD
Associate Professor of Surgery
e University of Texas Health Science Center McGovern Medical
School
Houston, Texas
Scott R. Steele, MD
University Hospitals Case Medical Center
Case Western Reserve University School of Medicine
Cleveland, Ohio
Ezra Steiger, MD
Consultant Digestive Disease Institute
Department of General Surgery
Cleveland Clinic
Cleveland, Ohio
David B. Stewart, Sr., MD, FACS, FASCRS
Associate Professor of Surgery
Department of Surgery/Division of Colorectal Surgery
Pennsylvania State University
Hershey Medical Center
Hershey, Pennsylvania
Scott A. Strong, MD, FACS, FASCRS
Chief, Gastrointestinal and Oncologic Surgery
Surgical Director, Digestive Health Center
Northwestern Medicine
James R. Hines, MD, Professor of Surgery
Northwestern University Feinberg School of Medicine
Chicago, Illinois
Paul H. Sugarbaker, MD, FACS, FRCS
Director, Center for Gastrointestinal MalignanciesMedStar
Washington Hospital Center
Washington, D.C.
Ursula M. Szmulowicz, MD, FASCRS
Retired Sta Surgeon
Department of Colorectal Surgery
Cleveland Clinic
Cleveland, Ohio
Té Vuong, MD, FRCP
Jewish General Hospital
McGill University
Montreal, Quebec, Canada
Steven D. Wexner, MD, PhD (Hon), FACS, FRCS, FRCS
(Ed)
Professor and Chairman
Department of Colorectal Surgery
Director, Digestive Disease Institute
Cleveland Clinic
Florida Florida Atlantic University
Florida International University
Weston, Florida
Mark H. Whiteford, MD, FASCRS
Gastrointestinal and Minimally Invasive Surgery Division
e Oregon Clinic
Director of Colon and Rectal Surgery
Providence Cancer Center
Portland, Oregon
Maria Widmar, MD, MPH
Icahn School of Medicine at Mount Sinai
Memorial Sloan Kettering Cancer Center
New York, New York
Kirsten Bass Wilkins, MD, FACS, FASCRS
Clinical Assistant Professor Surgery
Robert Wood Johnson University Hospital
New Brunswick, New Jersey
Jon Worsey, MBBS, FRCS, FACS, FASCRS
Sta Surgeon
Scripps Memorial Hospital
La Jolla, California
Massarat Zutshi, MD
Associate Professor of Surgery
Lerner College of Medicine of Case Western Reserve University
Sta Surgeon
Colorectal Surgery
Cleveland Clinic Foundation
Cleveland, Ohio
Matthias Turina, MD, PhD
Section Head, Coloproctology
Division of Visceral and Transplant Surgery
University of Zürich Hospital
Zürich, Switzerland

preface to the
third edition
When this edition of Current erapy in Colorectal Surgery was con-
ceived, Editor-in-Chief Victor Fazio was an integral part of the team.
Since then he has been lost to us, and we are the poorer for his loss.
is book is akin to a festschri in his memory.
e new edition continues the surgical and educational philosophies espoused by Vic Fazio, philosophies that have made the book
a unique volume much loved by surgical residents and surgeons
managing colorectal diseases throughout the world. We, the current
editors, have sought to achieve a uniform style that facilitates this edition’s use as a practical handbook of which Vic would be proud.
is is not meant to be an all-inclusive encyclopedia of the literature on colorectal surgery; there are other books that serve that
function. We aim to provide for the reader a very practical aid to the
management of patients suering from any of the conditions within
the full spectrum of colorectal disease. We chose expert authors and
asked them to focus on the practicalities of their topics, highlighting
dicult and controversial issues. ey were charged with providing
advice in the same way that an experienced, worldly-wise surgeon
shares wisdom with a young colleague. We hope that the book will
not linger on the shelf, but rather will be in constant use in meeting
the daily clinical challenges that are the essence of our profession.
In this edition, we have maintained the emphasis on current practice in the light of recent developments in colorectal disease and provided a state-of-the-art understanding of the conditions. e same
old chapters are here, with simple instruction in the basics of their
topics updated with the latest information. New chapters have been
added with emphasis on the way that health care is heading into the
21st century. e chapters on risk assessment, operating on the highrisk patient, and outcomes in general address the increasing emphasis on quality, while the chapters on documentation and coding and
enhanced recovery pathways are essential reading in this time of
value-based reimbursement. We have a whole section on complications, because complications are inevitable in a busy colorectal surgical practice, and we all need help in minimizing their incidence
and optimizing their management. ere are ve chapters dealing
with rectal cancer, which reects the major role that colorectal surgeons are expected to play in treating this condition. Other chapters
that are well worth a read include those on short bowel syndrome,
small bowel transplantation, pouchitis, and the medical management
of IBD. e chapters relating to pouch creation and complications
incorporate the techniques and principles developed and espoused
by Vic; this was an area close to his heart and where his skills were
superlative. e continually advancing area of hereditary colorectal
cancer is also well, and helpfully, covered.
Finally we hope that, in reading this, you will hear the gru, Australian accent of Vic Fazio as he dispenses the wisdom and accumulated experience of his 40 years of practice.
James M. Church, Conor P. Delaney, and
Ravi P. Kiran
xiii

acknowledgments
To my wife, Lois Church, in appreciation of her seless love and support.
James M. Church
To Clare for her love and support, and to my parents, without whose direction and support I would not have entered medicine.
Conor P. Delaney
To my wife, Madhu, for her love and support, and my parents for their guidance and encouragement.
Ravi P. Kiran
xiv

contents
1. A P R
1. Anatomy and Physiology of the Colon, Rectum, and Anal
Canal 3
Marylise Boutros and Philip H. Gordon
2. Hemorrhoids 12
Anthony J. Senagore
3. Chronic Anal Fissure 16
Siraj Rajaratnam and Ian Lindsey
4. Anorectal Abscess 21
Ravi P. Kiran
5. Anal Fistula 24
Mark L. Manwaring
6. Rectovaginal Fistula 30
Tracy Hull
7. Pilonidal Sinus 36
Tim Slack, Graham L. Newstead, and Mark Muhlmann
8. Perianal Hidradenitis Suppurativa 41
Mark L. Manwaring
9. Management of Pruritus Ani 43
J. Andres Cervera-Servin, Rodney J. Kratz, and Daniel P. Froese
16. Pelvic Pain 73
Joseph R. Notaro and Kirsten Bass Wilkins
17. Anorectal Congenital Disorders 77
Andrea Bischoff and Alberto Peña
18. Hirschsprung Disease 83
Andrea Bischoff and Alberto Peña
2. R P R
19. Fecal Incontinence 93
P. Ronan O’Connell
20. Rectal Stricture: Etiology and Management 98
William Sangster and David B. Stewart, Sr.
21. Management of Fecal Impaction 102
Sergio Larach and Beatriz Martin-Perez
22. Rectal Prolapse 107
Andrew J. Russ and Conor P. Delaney
23. Solitary Rectal Ulcer Syndrome 111
David Bartolo
24. Rectocele 114
Preetha Ali and Richard P. Billingham
10. Cause and Management of Anal Stenosis 48
Theodore E. Eisenstat and Jason Penzer
11. Management of Anal and Perianal Warts 53
Jennifer Blumetti and Jose R. Cintron
12. Anorectal Venereal Infections 57
Victor L. Modesto and Lester Gottesman
13. Management of High-Grade Squamous Intraepithelial
Lesion (Formerly Bowen Disease) and Paget
Disease 62
Nicholas La Gamma and John Procaccino
14. Anal Melanoma and Basal Cell Cancer of the Perianal
Region 65
Kurt Melstrom and Joseph Martz
15. Anal Carcinoma 68
Timothy J. Ridolfi and Kirk A. Ludwig
25. Rectal Foreign Bodies 118
Joanne Favuzza
26. Diagnosis and Management of Sacral and Retrorectal
Tumors 121
Sharon Grundfest-Broniatowski and Ajit Krishnaney
27. Management of Rectal Villous Tumors 132
James M. Church
28. Preoperative Evaluation of the Patient with Rectal
Cancer: Staging and Strategy 135
Marylise Boutros and Steven D. Wexner
29. Cancer of the Rectum: Neoadjuvant erapy 141
Té Vuong, Aurélie Garant, and Tamim Niazi
30. Cancer of the Rectum: Operative Management 146
Knut Magne Augestad, Benjamin Crawshaw, and
Conor P. Delaney
xv

xvi
CONTENTS
31. Local Treatment of Rectal Cancer 152
Maria Widmar and Julio Garcia-Aguilar
32. Locally Recurrent Rectal Cancer: Management and
Follow-up 157
Vanessa W. Hui, Harvey G. Moore, and José G. Guillem
33. Perineal Hernia 162
David E. Beck
3. C
34. Preoperative Preparation of the Patient for Colon and
Rectal Surgery 167
Danielle M. Pickham, Terrell C. Hicks, and David A. Margolin
35. Medical Treatment of Ulcerative Colitis and Other
Colitides 174
Aaron Brzezinski
36. Chronic Ulcerative Colitis: Surgical Options 186
Ravi P. Kiran
37. Management of Acute Toxic Colitis and
Megacolon 191
Ursula M. Szmulowicz and Victor W. Fazio
38. Pelvic Pouch: Complications and eir
Management 197
Ravi P. Kiran
39. Pouchitis and Functional Complications of the Pelvic
Pouch 201
Bo Shen
40. Continent Ileostomy 204
Jon Worsey and Victor W. Fazio
41. Unhealed Perineal Wound 209
Jesse Moore and Neil Hyman
42. Medical Management of Crohn Disease 213
Edith Y. Ho, Jeffry A. Katz, and Fabio Cominelli
43. Management of Crohn Colitis 217
Scott A. Strong
44. Management of Perianal Crohn Disease 222
James M. Church
45. Cecal Ulcer 226
Peter G. Deveaux and Michael H. McCafferty
46. Pseudomembranous Clostridium Dicile Colitis 228
Javier Salgado Pogacnik, Jennifer Holder-Murray, and
David S. Medich
47. Cytomegalovirus Ileocolitis and Kaposi Sarcoma in
HIV/AIDS 231
Henry R. Govekar and Dana R. Sands
48. Diagnosis and Management of Acute Colonic
Diverticulitis 234
Daniel L. Feingold and Ravi P. Kiran
49. Surgical Treatment of Diverticulitis and Its
Complications 239
Raul M. Bosio and Conor P. Delaney
50. Lower Gastrointestinal Hemorrhage 244
Caroline C. Jadlowiec and Jeffrey L. Cohen
51. Large Bowel Obstruction 249
David P. O’Brien, Kim C. Lu, and Mark H. Whiteford
52. Colonic Volvulus 255
Deborah S. Keller
53. Colonic Pseudo-obstruction (Ogilvie Syndrome) 260
Theodore J. Saclarides and Elizabeth Berger
54. Management of the Malignant Polyp 264
Skandan Shanmugan and Cary B. Aarons
55. Colorectal Cancer Screening and Surveillance 267
Carole Macaron and Carol A. Burke
56. Molecular Genetics of Colorectal Cancer 273
James M. Church
57. Polyposis Syndromes 275
James M. Church
58. Desmoid Disease 281
James M. Church
59. Hereditary Nonpolyposis Colorectal Cancer and Lynch
Syndrome 285
Matthew F. Kalady
60. Cancer of the Appendix and Pseudomyxoma Peritonei
Syndrome 292
Paul H. Sugarbaker
61. Surgical Management of Cancer of the Colon 301
In Ja Park and George J. Chang
62. Management of Metastatic Colorectal Cancer 309
Marcus S. Noel and Alok A. Khorana
63. Management of Colorectal Liver Metastasis 314
Terence Jackson, Nikita Neha Machado, and Christopher T. Siegel
64. Colorectal Metastases to the Lung 320
Philip A. Linden
65. Nonepithelial Colorectal Tumors 323
Angelle M. Gelvin and Guy R. Orangio
66. Management of Colonic Ischemia 328
Vikram Reddy and Walter E. Longo
67. Colon and Rectal Trauma 334
Scott R. Steele and Eric K. Johnson
68. Endometriosis of the Colon and Rectum 341
H. Randolph Bailey, Michael J. Snyder, and Colin P. Bird
69. Pneumatosis Cystoides Intestinalis 345
Susan Galandiuk, Jonathan Rice, Peter G. Deveaux, and Russell Farmer
70. Constipation 349
Evie Carchman and Massarat Zutshi

CONTENTS
xvii
4. S I
71. Small Bowel Obstruction 359
Matthias Turina and Ravi P. Kiran
72. Medical Management of Short Bowel Syndrome 366
Mary Jo Alberino, Dileep Atluri, and Ezra Steiger
73. Surgery for Gut Failure: Auto-Reconstruction and
Allo-Transplantation 372
Kareem Abu-Elmagd, Ajai Khanna, Masato Fujiki, Koji Hashimoto,
Galal El-Gazzaz, Abdullah Shatnawei, and Guilherme Costa
74. Crohn Disease of the Duodenum, Stomach, and
Esophagus 385
Pasha J. Nisar and Ravi P. Kiran
75. Management of Small Bowel Crohn Disease 388
Scott A. Strong
76. Small Bowel Neoplasms 393
Susan L. Gearhart
77. Neuroendocrine Tumors of the Small and Large
Intestine 396
Seraina Faes and Dieter Hahnloser
78. Enterocutaneous Fistulas 404
Josef E. Fischer
79. Acute and Chronic Mesenteric Ischemia 412
Susan Galandiuk, Jeffrey R. Jorden, Jonathan Rice, and Peter G. Deveaux
80. Radiation Enteritis and Proctocolitis 418
Sandy H. Fang and Jonathan E. Efron
83. Nutritional Support in Colorectal Surgery 439
John L. Rombeau, Kimberly J. Hwa, and Dan Eisenberg
84. Prevention and Management of Sepsis 445
Dan Geisler and C. Neal Ellis
85. Management of Anastomotic Leak 448
Nathan Smallwood and James Fleshman
86. Complications of Colonoscopy 452
Rhodri J. Codd and Peter M. Sagar
87. Management of Hemorrhage During Pelvic Surgery 456
John H. Marks and Grace A. Montenegro
88. Urologic Issues in Colorectal Surgery 462
Bradley C. Gill and Drogo K. Montague
89. Prevention and Treatment of Complications of
Laparoscopic Colorectal Surgery 468
Benjamin Crawshaw, Knut Magne Augestad, and Conor P. Delaney
90. Prevention and Management of Ostomy
Complications 472
Victor W. Fazio
91. Stoma and Wound Considerations: Nursing
Management 477
Paula Erwin-Toth and Barbara J. Hocevar
92. Measuring Outcomes 486
Robin S. McLeod
93. Medical Documentation and Coding for the Colorectal
Surgeon 490
Anthony J. Senagore
5. C ( O
M T)
81. Colorectal Surgery in the High-Risk Patient 427
Walter A. Koltun and Tara M. Connelly
82. Reoperative Pelvic Surgery 434
Jon Worsey and Victor W. Fazio
94. Enhanced Recovery Pathways Aer Colorectal
Surgery 493
Henrik Kehlet, Andrew G. Hill, and Robin H. Kennedy
95. Managing Complex Ventral/Parastomal Hernias in
Colorectal Surgical Patients 496
Clayton C. Petro and Michael J. Rosen

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