In 2011, after a preliminary work in a dry labo­ratory setting, the next step was validation in a cadaveric model. This was conducted using the da Vinci S model, which, at the time, was the only system for cadaveric evaluation (Fig.16.3). With the introduction of the GelPOINT Path Transanal Access Platform (Applied Medical, Inc. Rancho Santa Margarita, CA), the rst sin­gle port specically designed for transanal access, the experiments were conducted utiliz­ing this platform at the Global Robotics Institute (Celebration, FL, USA), and it was demon­strated that intricate, precise operative maneu­verability was quite feasible [27]. Specically, local excision (full thickness) and suturing with intraluminal knot tying was possible, and the level of difculty was subjectively determined to be low by the operators [27]. Potential advantages of robotic TAMIS over standard TAMIS include image stabilization under single-surgeon control, 3D stereoscopic video processing, tremor cancelation, and image magnication. In theory, this could lead to improved excision quality, which is believed to be a factor as to why advanced transanal plat­forms carry an advantage over conventional parks local excision [28–31]. While TEM had been the gold standard for advanced endolumi­nal rectal surgery for over a quarter century, the birth of TAMIS seemed to give rise to other options–since it was not only disposable, but also economical (as the material from which the platform is constructed are much less important in retaining the quality of excision, and for single- use devices the durability is not relevant). Perhaps the most economical of all modern platforms is the simplest – the glove port. Introduced rst in 2012 by A.Carrara as a technique for TEM [32], the glove port was subsequently applied by R. Hompes as an interface for robotic TAMIS with excellent results later that year [33] and represented an effective, low-cost interface quite suitable for transanal access [34].