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45 Colonic: Diverticulitis
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Colonic Conditions: Large Bowel Obstruction

SarahB.Stringeld andBardC.Cosman
46
Refer toAlgorithm inFig. 46.1
A. Although large bowel obstruction (LBO) may
have a long prodromal period, the clinical presentation is usually acute. A thorough his­tory is important, though focus should be on bowel movements, abdominal pain, and a­tus. Common associated symptoms include abdominal distention, crampy pain, nausea and vomiting, obstipation or constipation, and bloating relieved by defecation. Signicant prodromal symptoms may include chronic constipation, stool caliber change, and intermittent left lower quadrant pain over months to years. A physical examination should be performed, focusing on the abdo­men to assess for tenderness, peritoneal signs, and any mass or fullness. Additionally, the patient should be checked for incarcerated inguinal and femoral hernias, and a rectal examination should be performed to assess stool consistency and the contents of the rec­tal vault.
B. Due to potential morbidity and mortality, sus-
picion of LBO should lead to rapid evaluation
S. B. Stringeld Department ofSurgery, University ofCalifornia San Diego Health System, San Diego, CA, USA
B. C. Cosman (*) Surgical Services, VA San Diego Healthcare System, University ofCalifornia School ofMedicine, San Diego, CA, USA
and surgical consultation. Pain relief, control of vomiting with antiemetics and/or nasogas­tric decompression, and correction of uid and electrolyte abnormalities should occur simultaneously with diagnostic evaluation. It is unproven, but reasonable, to give antibiot­ics with gram-negative aerobic and anaerobic coverage to patients with suspected or con­rmed LBO if the patient appears septic and there is concern for perforation. Laboratory studies can assess degree of dehydration and electrolyte imbalance, and evaluate for infec­tion, anemia, and ischemia.
C. Radiographic studies can conrm obstruction
and identify its cause or other pathology causing the patient’s symptoms. Computed Tomography (CT) is the imaging of choice for suspected LBO, as it can conrm the diag­nosis, identify intraluminal, mural, and extra­mural causes, and detect inammation and bowel ischemia. The presence of a transition point in the colon can make the diagnosis of LBO, though it does not always distinguish between mechanical obstruction and pseudo­obstruction. Intravenous and oral contrast can often help delineate between partial and com­plete obstruction, ileus, and small bowel obstruction. Rectal contrast may be useful when the suspected obstruction is in the rec­tum or sigmoid, and it allows a clearer dis­tinction between mechanical and functional obstruction. Water-soluble contrast enema
© Springer Nature Switzerland AG 2020 S. R. Steele etal. (eds.), Clinical Decision Making in Colorectal Surgery,
https://doi.org/10.1007/978-3-319-65942-8_46
363
364
Fig. 46.1 Algorithm for evaluation and management of large bowel obstruction
S. B. Stringeld and B. C. Cosman
with plain lms has been replaced by CT with rectal contrast, but the enema itself has thera­peutic value in intussusception, regardless of what imaging modality is used to monitor it. Plain lms are of little value when compared to CT, although upright chest radiographs may be useful as an initial screen for pneu­moperitoneum, pneumatosis intestinalis, and portal venous gas, suggesting a concomitant perforation or ischemia that might necessitate prompt surgical intervention. Sigmoid or cecal volvulus (Fig.46.2) may have a kidney­bean or giant-loop appearance on abdominal radiographs. Abdominal radiographs may also help distinguish constipation from LBO and may localize the site of obstruction, showing colonic dilation proximal to the obstruction and a paucity or absence of gas distal to the obstruction.
D. All patients with peritoneal signs on abdomi-
nal examination or signs of perforation or ischemia on radiographs should undergo prompt surgical exploration. Cecal diameter greater than 12cm, unless it is known to be chronic, should raise concern for impending perforation, and urgent decompression should
Fig. 46.2 Cecal volvulus on plain lm
be considered, either via endoscopic or surgi­cal intervention. The patient without signs of an acute abdomen can undergo further evaluation and consideration of whether sur­gical or endoscopic intervention is indicated,
46 Colonic Conditions: Large Bowel Obstruction
365
or whether non-operative measures, e.g. for pseudo-obstruction, may be appropriate.
E. Colonic malignancy is the most common
cause of LBO.The most common locations are the rectum, sigmoid colon, and the splenic exure; while lesions in the right colon, where stool is liquid, require the lumen to be almost completely closed to cause clinical LBO. In the absence of perforation or isch­emia, endoscopic dilation and stenting of masses and strictures may be helpful in selected cases, and may provide an alterna­tive to multistage surgery. Stenting or dilation permits relief of acute obstruction, resuscita­tion of the patient, and mechanical bowel preparation prior to resection and re­anastomosis, thus potentially avoiding ileos­tomy or colostomy. Stenting is most often successful for left-sided lesions. Right-sided lesions and distal rectal lesions tend to be much more difcult technically and not great candidates. Patients with left-sided obstruc­tion may be treated with a decompression tube as a bridge to surgery. Palliative stenting may be an option in patients who are poor surgical candidates or who have advanced cancer.
F. Acute colonic volvulus may account for
10–15% of LBO. In the United States, sig­moid volvulus is 3–4 times more common than cecal volvulus; however, their relative frequency varies greatly internationally. In a stable patient, sigmoid volvulus can be treated with endoscopic reduction and decompres­sion. Yet, if mucosal ischemia is found on colonoscopy, the procedure should be aborted and the patient should undergo urgent surgi­cal exploration. Recurrence of volvulus after decompression is common and expected, therefore surgical resection is indicated in all but the sickest patients. Elective resection should be performed in all patients with cecal volvulus and in patients with sigmoid volvu­lus following successful endoscopic reduc­tion, if they are surgical candidates from a co-morbidity standpoint. Emergent operation is indicated in patients for whom endoscopic reduction is not successful.
G. Acute diverticulitis can rarely present as par-
tial or complete LBO due to bowel wall edema and/or pericolonic inammation. Obstruction usually occurs after multiple episodes, which causes narrowing and stricture formation. Diverticulitis is seen on CT as segmental, symmetric bowel wall thickening with hyper­emia, in a longer segment than a typical malignancy (Fig. 46.3). However, it can be difcult to distinguish radiographically between diverticulitis and cancer, so colonos­copy and biopsy is valuable if there is the opportunity. Principles of treatment are the same as with malignant obstruction. Elective resection should be offered to patients with recurrent diverticulitis with LBO, following resolution of an acute episode.
H. Intussusception can successfully be treated with
a contrast enema in 60–80% of cases. This is more successful in children, in whom a patho­logic lead point is unlikely. In adults, a patho­logic lead point is usually present, and patients are more likely to require elective surgery after successful reduction by contrast enema. The lead point should be investigated by colonos­copy after reduction of the intussusception. Urgent operation is indicated in all patients with signs of peritonitis or bowel perforation, or if reduction with contrast enema is unsuccessful.
I. Colonic ileus may not exist as a distinct entity:
certainly, the colon shares in generalized ileus, and arguably isolated colonic ileus may be the
Fig. 46.3 Diverticulitis on CT
366
S. B. Stringeld and B. C. Cosman
same as acute colonic pseudo- obstruction. In principle, adynamic ileus of the colon is treated with conservative measures, including correc­tion of uid and electrolyte abnormalities and treatment of the underlying disorder. Nasogastric tube decompression may be helpful if the patient is vomiting. Medications that slow colonic motility should be stopped or avoided.
J. Acute colonic pseudo-obstruction, also called
Ogilvie’s syndrome, is treated the same as colonic ileus if there are no signs of colonic perforation. Additionally, IV neostigmine and/ or colonoscopic decompression may be effec­tive. Surgery may be required in refractory cases and those complicated by perforation.

Suggested Reading

Frago R, Ramirez E, Millan M, Kreisler E, del Valle E,
Biondo S. Current management of acute malignant large bowel obstruction: a systematic review. Am J Surg. 2014;207:127–38.
Jaffe T, Thompson W. Large-bowel obstruction in the
adult: classic radiographic and CT ndings, etiology, and mimics. Radiology. 2015;275:651–63.
Lopez-Kostner F, Hool GR, Lavery IC.Management and
causes of acute large-bowel obstruction. Surg Clin North Am. 1997;77:1265–90.
Yeo HL, Lee SW. Colorectal emergencies: review and
controversies in the management of large bowel obstruction. J Gastrointest Surg. 2013;17:2007–12.
Zahid A, Young CJ.How to decide on stent insertion or
surgery in colorectal obstruction? World J Gastrointest Surg. 2016;8:84–9.

Colonic Conditions: Volvulus

RichardGarnkle andMaryliseBoutros
47

Refer to Algorithm in Fig. 47.1

Introduction
Colonic volvulus accounts for 10–15% of all large bowel obstructions in Western countries, and is the third leading cause behind colorectal cancer and diverticular disease. Volvulus refers to torsion of a segment of bowel on its mesen­tery; colonic volvulus involves the sigmoid colon and cecum in over 95% of cases, with the transverse colon and splenic exure more sel­dom affected. With rotation of the redundant and mobile segment of colon, closed-loop luminal obstruction and mesenteric malperfusion ensue, leading to the symptoms of bowel obstruction and possible ischemia. If not treated urgently, colonic volvulus can be fatal, and carries a vari­able mortality rate that can exceed 50% when gangrenous colon is present.
The sigmoid colon accounts for the majority of colonic volvulus, with a variable incidence. The anatomic abnormality that predisposes to volvulus is a long redundant sigmoid colon with a narrow mesenteric attachment.
R. Garnkle · M. Boutros (*) Division ofColon and Rectal Surgery, Jewish General Hospital, Montreal, QC, Canada
The incidence of cecal volvulus has increased steadily over the past decade. Like its sigmoidal counterpart, cecal volvulus occurs secondary to organoaxial rotation of the colon. The basic ana­tomic requirement is a sufciently mobile cecum and ascending colon, which is present in 11–22% of adults according to autopsy studies. Cecal bas­cule, a distinct and less commonly observed entity, involves anterosuperior folding of the cecum over a xed ascending colon. Though it presents similarly to cecal volvulus, it does not involve axial rotation of the bowel and thus does not result in mesenteric vascular obstruction.
A. Sigmoid volvulus usually occurs in the
elderly with a mean age of presentation of 70years old, and affects males in a 2:1 ratio. Patients typically have many medical comor­bidities, and often suffer from chronic consti­pation, cathartic/laxative abuse, or colonic motility disorders. They are also dispropor­tionately institutionalized with neuropsychi­atric conditions. In many third-world countries, where sigmoid volvulus represents the leading cause of large bowel obstruction, Chagas disease and high-ber diets have been implicated in the pathogenesis of the redun­dant sigmoid, and affected adults are typi­cally younger, between 40–50 years old. Patients with a cecal volvulus are usually female (3:1) and 10–20 years younger than those with sigmoid volvulus. Precipitating
© Springer Nature Switzerland AG 2020 S. R. Steele etal. (eds.), Clinical Decision Making in Colorectal Surgery,
https://doi.org/10.1007/978-3-319-65942-8_47
367
368
Fig. 47.1 Sigmoid volvulus algorithm
R. Garnkle and M. Boutros
factors include surgical adhesions, congenital bands, pregnancy, and colonic atony.
B. Colonic volvulus may be difcult to distin-
guish from other forms of bowel obstruction on history and physical examination alone. Sigmoid volvulus tends to have an insidious onset of progressive abdominal pain, fol­lowed by nausea, vomiting, abdominal dis­tension and obstipation. Patients tend to present after 3–4 days of symptoms, and per­haps longer in institutionalized patients. The symptoms of cecal volvulus are similar, but affected individuals are more likely to present earlier with steady abdominal pain. In both cases, physical examination may reveal vary­ing degrees of abdominal tenderness, disten­sion and tympany. The presence of hemodynamic abnormalities (tachycardia or hypotension), fever, rigidity, severe guarding, and rebound tenderness are indicative of colonic ischemia and/or perforation.
C. The diagnosis of colonic volvulus usually
relies on a combination of imaging modalities (Fig. 47.2). Plain abdominal radiographs are diagnostic of sigmoid volvulus in roughly 50% of cases, and classically feature a mark-
edly distended, gas-lled anhaustral colon extending from the pelvis to as high as the dia­phragm, referred to as the “bent inner tube”, “omega”, or “coffee-bean” sign. The addition of a water-soluble contrast enema can improve the diagnostic accuracy of plain radiograph up to 90%, giving the characteristic “bird’s beak” sign as the contrast tapers off to the point of obstruction. Abdominal radiographs are less diagnostic of cecal volvulus, with only 15% of cases readily recognizable. Unless the clinical exam or radiograph ndings warrant urgent exploratory laparotomy, contrast-enhanced CT scan has become the diagnostic test of choice for both sigmoid and cecal volvulus. The “whirl sign” is specic for volvulus, rep­resenting the swirling appearance of the col­lapsed bowel and its mesentery.
D. The initial assessment of a patient with sus-
pected colonic volvulus should focus on iden­tifying signs of colonic ischemia or perforation. Vital sign abnormalities and/or peritonitis on exam, free air on plain radio­graph or CT scan, and leukocytosis or ele­vated serum lactate are all indicative of ischemia or perforation, and the presence of
47 Colonic Conditions: Volvulus
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Fig. 47.2 Characteristic imaging ndings for sigmoid volvulus. (a) “Coffee-bean” sign on plain radiograph. Note the thick inner wall, representing a double-layer of apposed bowel wall (red arrows). (Reused with permis­sion © 2015 Springer) (b) “Bird’s beak” sign with rectal
any one of these should prompt the consider­ation for urgent operation. Management begins with the general principles of bowel obstruction and/or intra-abdominal sepsis: uid resuscitation, correction of electrolyte abnormalities, bladder catheterization for urine output monitoring, nasogastric tube insertion (to decompress the stomach and small bowel, and to prevent aspiration), and intravenous antibiotics in cases of ischemia or perforation.
E. In the absence of suspected ischemia or per-
foration, the initial treatment of sigmoid vol­vulus is typically endoscopic detorsion with exible sigmoidoscopy (Fig.47.1). If signs of colonic ischemia or gangrene are observed endoscopically (blood or dusky mucosa), detorsion and colonic manipulation should be immediately aborted to avoid perforation of the bowel or bacterial translocation, and an urgent operation should be planned. In the absence of these signs, detorsion is successful in 60–95% of cases. Following detorsion, a rectal tube should be left in place to allow for continued colonic decompression and to pre­vent re-torsion of the colon. To ensure proper placement, the rectal tube can be inserted over a guide wire through the sigmoidoscope, reaching just past the point of the volvulus. If detorsion is unsuccessful, an urgent operation is warranted.
contrast. Note the smooth tapering of contrast as the colon narrows at the point of obstruction (red arrow). (Reused with permission © 2015 Springer) (c) “Whirl” sign seen on CT scan (white circle). (Reused with permission © 2013 John Wiley and Sons Inc.)
Unlike with sigmoid volvulus, endoscopic detorsion is not recommended as part of the management strategy of cecal volvulus. Various small studies have reported low suc­cess rates in achieving cecal reduction with endoscopy, and have described it as techni­cally challenging. As such, surgery is always performed to relieve the obstruction, detorse the bowel, and address the colon which is prone to volvulize again.
F. Many operative interventions have been
described for the treatment of sigmoid vol­vulus with varying success rates: simple detorsion, sigmoidopexy (intra- or extra­peritoneal), mesosigmoidoplasty (Fig.47.3), and colectomy with or without primary anastomosis. Of all, sigmoid colectomy is the best option to prevent recurrences. The decision to perform a primary anastomosis must take into account the timing of the operation (urgent vs. semi-elective), intraop­erative ndings (bowel viability, contamina­tion), the clinical status of the patient (hemodynamics, metabolic derangements), and the patient’s baseline risk (nutritional status, comorbidities).
All urgent operations should be performed via midline laparotomy. In general, colec­tomy with end colostomy (with mucous s­tula or Hartmann’s closure) should be performed in the presence of gangrenous