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Defecation
Puborectalis
Anorectal angle is
31 Pelvic Outlet Obstruction
Fig. 31.2 Cross-section of the normal pelvic oor musculature at rest (a) and during defecation (b). During defecation, the puborectalis muscle relaxes, and the anorectal angle (shown in red) broadens
a
Uterus
Bladder
Puborectalis
muscle
(contracted)
b
239
Anorectal angle
Anal sphincter (closed)
Rest
muscle
(relaxed)
asked if they have a history of sexual abuse, and also whether any psychiatric conditions are present, including eating disorders, pho­bias, and obsessive-compulsive disorder.
J.In-ofce examination by the surgeon is essen-
tial, as a skilled examiner is likely to identify obstructive defecation. After an abdominal exam the patient should be placed in the prone jackknife or left lateral decubitus position, an in-depth anorectal exam is performed, begin-
ning with inspection of the anoderm. The perineum should be examined for the presence of scars and bulk to the perineal body. Assessment should note the presence of hem­orrhoids, skin tags, ssures, or other lesions and pin- prick sensitivity of the anoderm should be assessed. Digital rectal exam should evaluate resting and squeeze tone, or any masses, as well as the presence and consis­tency of stool in the vault. Presence or absence
broadened
Anal sphincter (open)
240
J. S. Davids
Table 31.1 Important elements of the initial history in a patient with suspected pelvic outlet obstruction
Duration of symptoms, age of onset (childhood, teenage years, or adulthood)
Bowel movement frequency, consistency, timing (erratic or consistent)
Toileting habits: daily routine, sitting, straining, perineal or vaginal splinting
Is there tissue protrusion or a “bulge” with defecation? Is there pain or blood?
Fecal incontinence Urinary or sexual symptoms Abdominal pain, cramping, bloating Emotional or psychological stress, identiable
symptom triggers Diet: ber and water intake
of rectocele should be evaluated. Additionally, on digital rectal exam, the patient should be asked to squeeze tightly “as if holding back a bowel movement” and then asked to relax. Next, the patient should be asked to “bear down as if having a bowel movement.” Patients with normal pelvic oor mechanics should relax the puborectalis sling and sphinc­ter complex, and there should be appreciable descent of the pelvic oor; the examiner’s n­ger will shift anteriorly. Patients with pelvic outlet obstruction will tighten rather than relax the sphincter complex, and consequently the pelvic oor will contract and not descend. With a clean glove, the vagina may be pal­pated to assess for evidence of uterovaginal prolapse.
K. Anoscopy should be performed, specically
looking for evidence of bulky internal hemor­rhoids, proctitis, or mucosal redundancy. If there is concern for signicant hemorrhoidal, mucosal, or full thickness rectal prolapse, the patient should be examined after straining on the commode.
L.Diagnostic evaluation. Prior records should be
carefully reviewed to avoid unnecessarily repeating often uncomfortable or invasive studies. With that being said, some diagnostic studies are user-dependent or may change over time, and may therefore need to be repeated. Careful consideration should be given to any diagnostic evaluation to determine what spe-
cic question will be answered, and how it could impact management. Accordingly, many so-called “abnormal” ndings seen on these diagnostic studies are also seen in asymptom­atic individuals, leading to false- positives, fur­ther obscuring interpretation.
M.Endoscopic evaluation. Patients should have
either exible sigmoidoscopy or colonoscopy depending on their age, symptoms, and the index of suspicion of co-existing abnormali­ties of the lower gastrointestinal tract.
N.Evaluation of colonic motility. One method to
assess colonic motility is to perform serial abdominal X-rays after the patient swallows a capsule that dissolves in the stomach, releas­ing radiopaque markers. The X-rays will show the progression of the markers over time. Patients are generally instructed to discon­tinue all of their laxatives, motility agents, and enemas for the duration of the test; however, the clinician and patient may decide to con­tinue these agents, as the study may otherwise prove to be intolerable with respect to symp­toms. X-rays are typically obtained on days 1, 3, and 5. The “classic” nding for patients with pelvic outlet obstruction is that the mark­ers will cluster in the rectosigmoid colon, as they are not being passed through the pelvic oor musculature into the lower rectum (and then evacuated). Patients who also have slow transit constipation may need additional lms on day 7, 9, or potentially later to determine if they do eventually cluster in the rectosigmoid colon; transit studies in these patients may be challenging to interpret.
Most commonly used is the Sitzmark cap­sule (Konsyl Pharmaceuticals, Easton, MD), which contains 24 radio-opaque rings and dis­solves when ingested. A simple image obtained 5 days after capsule ingestion will easily diagnose normal transit (Fig.31.3).
O. Anorectal physiology evaluation. A compre-
hensive evaluation by a highly skilled and experienced surgeon or technician is essential. Patients should be reassured that the examina­tion should not be painful and will last 30–45min. Patients need to perform an enema prep 90min prior to the procedure.
31 Pelvic Outlet Obstruction
Fig. 31.3 Colonic transit capsule (Konsyl Pharmaceuticals, Easton, MD), which contains 24 radiopaque rings and dis­solves when ingested. A simple image obtained 5days after capsule ingestion will easily diagnose normal transit
(a) Manometry: A probe attached to a pres-
sure transducer is inserted into the rectum, and will enable the examiner to determine rectal pressures at rest, as well as in response to stimuli or to voluntary move­ment. Using a balloon inated in the rec­tum, manometry can be used to assess rectal sensation and compliance, by deter­mining (1) the volume at which the bal­loon is sensed, (2) the volume that triggers need to have a bowel movement, and (3) the maximum tolerated volume. Additionally it can be used to test RAIR and RAER by monitoring the reex trac­ing of the internal and external sphincter when the balloon is rapidly inated with 10-30mL of air to simulate rectal disten­sion by stool.
(b) Balloon expulsion: A balloon lled with
50cc of warm water is inserted into the rectum, to simulate the presence of stool.
241
Patients are instructed to expel the bal­loon. Most healthy subjects can pass the balloon in under 60s. Failure to pass the balloon is highly specic for obstructive defecation, and around 50% sensitive.
(c) Electromyography (EMG): A probe is
used to quantify the electrical impulse of the pelvic oor muscles and sphincter complex at rest, with voluntary squeeze, and with Valsalva or simulated evacua­tion. EMG can be used to detect paradoxi­cal excitation of the pelvic oor during Valsalva.
(d) Transanal Ultrasound: 2D or 3D images
can be obtained with frequencies ranging from 6 to 16MHz. Images may demon­strate circumferential thickening of the internal anal sphincter, consistent with a history of chronic straining.
P. If the diagnosis is clear with the aforemen-
tioned initial evaluation, it is reasonable to move forward and treat the patient, starting with a conservative approach.
Q.If, by contrast, the diagnosis is still unclear, or
if there is evidence of multiple associated abnormalities, it is recommended to pursue further diagnostic evaluation.
R. Defecography is a useful adjunct study to
evaluate defecation mechanics in real time. It can be difcult to interpret, as normal, asymp­tomatic subjects may also manifest abnormal­ities on defecography. It is an excellent adjunct study if there is concern of concomi­tant rectocele, enterocele, cystocele, abnor­mal perineal descent, rectal intussusception, or if the balloon expulsion test was inconclu­sive. Patients undergoing defecography have barium paste placed into the rectum (approxi­mately 150mL). Contrast can also be placed in the vagina or instilled in the bladder, and patients may also ingest oral contrast to opacify the small intestine. While sitting on a commode, the patients are asked to evacuate the barium paste from the rectum, as serial images are captured using uoroscopy. Cine­defecography refers to a series captured using continuous uoroscopy. Studies of patients with pelvic outlet obstruction will demonstrate
242
J. S. Davids
a narrowing of the anorectal angle (or no change) with attempted defecation, with retention of the contrast, corresponding to paradoxical contraction (or nonrelaxation) of the puborectalis sling. Dynamic pelvic mag­netic resonance imaging (MRI), also referred to as dynamic MR proctography, can also be performed at some centers where this tech­nology is available. This is performed either in supine or sitting position (with open mag­net system) and images are taken while the patient strains, squeezes, and defecates. It does not require intravenous contrast, or con­trast to be instilled in the bladder, vagina, or small intestine. The rectum is distended with ultrasound gel. This modality may be particu­larly helpful to identify soft tissue planes in patients with complex anatomy from prior repairs, and also avoids ionizing radiation.
S.Ultrasound of the pelvic oor is also an effec-
tive adjunct to diagnose pelvic outlet obstruc­tion. Both transperineal and endoanal techniques are used to assess the anorectal angle and pelvic oor motion. The study is generally well-tolerated, is inexpensive, and is not associated with ionizing radiation expo­sure. Dynamic 4D ultrasound technology allows for 3D visualization of the pelvic organs and musculature as a real-time simula­tion of defecation. With most modern equip­ment, the operator can record and store multiple cine simulations. Despite its many advantages, dynamic 4D ultrasound is not widely available because it is highly operator­dependent, and therefore it is imperative that the examiner is skilled in this modality.
T. It is important that the clinician clearly
expresses honest, realistic goals of treatment and expectations for recovery with the patient. The goals of treatment are to improve defeca­tion mechanics and stool texture, which ulti­mately, for most patients, will result in a profound improvement in quality of life. Treatment of pelvic outlet obstruction can be extremely challenging and time-consuming. Rarely is pelvic outlet obstruction “cured” with one intervention or in just one setting. Surgical approaches to pelvic outlet obstruc-
tion are quite limited; therefore, treatment plans begin with conservative, simple mea­sures aimed at improving stool texture. The best treatment plans employ a multimodal approach (e.g., dietary changes and biofeed­back), reserving surgery for failure of the less­invasive approaches.
U. Dietary changes are employed as the rst-line
therapy to improve stool texture. Patients should increase their dietary ber intake to 25–30g per day, and may gradually increase to up to 50g per day. This goal can be accom­plished by adding high-ber cereal and pow­dered ber supplements such as psyllium, methylcellulose, polycarbophil, and wheat dextrin. Fiber wafer formulations or soluble ber gummies can help bulk up stool. Along with ber supplementation, patients should stay well-hydrated, particularly in the warmer weather, and consume 1–2L of uid over a 24h period. Patients with severe constipation may also need to add laxatives and other adjunct medications to soften hard stool.
V. Pelvic oor physical therapy can be helpful in
improving defecation mechanics in patients with pelvic outlet obstruction. Pelvic oor physical therapy is generally performed by a licensed physical therapist with specialized knowledge of pelvic oor anatomy and bio­mechanics. Additionally, biofeedback may be performed, which will allow the provider to evaluate the pelvic oor muscle pressure or with electromyography probes, which pro­vides some quantitative data to document improvement and areas for ongoing therapy. Reported efcacy of pelvic oor physical therapy in patients with obstructive defecation is mixed. A meta-analysis of a total of 38 stud­ies demonstrated signicant heterogeneity between techniques and approaches, but over­all, efcacy ranged from 69% to 75%.
W.Botulinum toxin A (Botox; Allergan; Madison,
NJ) has been shown in small studies to improve symptoms of pelvic outlet obstruc­tion. A study of 24 patients, in which botuli­num toxin (60 Units) was injected under ultrasound guidance in two sites on either side of the puborectalis muscle using a 23-gauge
31 Pelvic Outlet Obstruction
243
needle. Patients did not receive sedation or local anesthetic. Using this technique, the authors demonstrated symptomatic improve­ment in 19 patients (79%). The symptomatic improvement also correlated with increased anorectal angle on defecography. Given that the effects of the toxin only last 3months, it is unclear how often (and how many times) the injection would need to be repeated for main­tenance of long-term results.
X. Intestinal stoma creation should be considered
in select patients who continue to manifest refractory debilitating symptoms. Patients should be counseled that the need for a colos­tomy should not represent “failure,” as it can be a highly effective approach, and may enable them to move past their disease, and experi­ence an improved quality of life. Importantly, patients with evidence of concurrent slow­transit constipation should be considered for ileostomy and not colostomy. It is important to note that some patients may require an intestinal stoma due to their inability to undergo pelvic oor physical therapy due to physical or psychological coexisting condi­tions; it is therefore not necessary to reserve this option only for those with persistent symptoms despite non-surgical approaches.
In summary, pelvic outlet obstruction is a complex disease that can prove to be a signi­cant diagnostic and therapeutic challenge. The evaluation begins with a detailed history and physical exam. Diagnostic workup is individu­alized and involves ruling out other associated conditions, such as slow-transit constipation, pelvic organ prolapse, or internal rectal intus­susception. Initially, treatment strategies con­centrate on lifestyle and dietary changes, and also include pelvic oor physical therapy, bot­ulinum toxin injection, and lastly, surgery.

Suggested Reading

Anti M, Pignataro G, Armuzzi A, Valenti A, Iascone E,
Marmo R, etal. Water supplementation enhances the effect of high-ber diet on stool frequency and laxative
consumption in adult patients with functional consti­pation. Hepatogastroenterology. 1998;45(21):727–32.
Chiarioni G, Bassotti G, Monsignori A, Menegotti M,
Salandini L, Di Matteo G, etal. Anorectal dysfunction in constipated women with anorexia nervosa. Mayo Clin Proc. 2000;75(10):1015–9.
Colaiacomo MC, Masselli G, Polettini E, Lanciotti S,
Casciani E, Bertini L, et al. Dynamic MR imaging of the pelvic oor: a pictorial review. Radiographics. 2009;29(3):e35.
Dietz HP, Beer-Gabel M. Ultrasound in the investiga-
tion of posterior compartment vaginal prolapse and obstructed defecation. Ultrasound Obstet Gynecol. 2012;40(1):14–27.
Heymen S, Jones KR, Scarlett Y, Whitehead
WE.Biofeedback treatment of constipation: a critical review. Dis Colon Rectum. 2003;46(9):1208–17.
Maria G, Brisinda G, Bentivoglio AR, Cassetta E,
Albanese A.Botulinum toxin in the treatment of outlet obstruction constipation caused by puborectalis syn­drome. Dis Colon Rectum. 2000;43(3):376–80.
Maria G, Cadeddu F, Brandara F, Marniga G, Brisinda
G.Experience with type A botulinum toxin for treat­ment of outlet-type constipation. Am J Gastroenterol. 2006;101(11):2570–5.
Murad-Regadas SM, Regadas FS, Rodrigues LV, Souza
MH, Lima DM, Silva FR, etal. A novel procedure to assess anismus using three-dimensional dynamic anal ultrasonography. Colorectal Dis. 2007;9(2):159–65.
Murad-Regadas SM, Regadas FS, Barreto RG, Rodrigues
LV, de Souza MH.A novel two-dimensional dynamic anal ultrasonography technique to assess anismus comparing with three-dimensional echodefecography. Colorectal Dis. 2009;11(8):872–7.
Murad-Regadas SM, Regadas FS, Bezerra CC, de
Oliveira MT, Regadas Filho FS, Rodrigues LV, etal. Use of biofeedback combined with diet for treatment of obstructed defecation associated with paradoxical puborectalis contraction (anismus): predictive fac­tors and short-term outcome. Dis Colon Rectum. 2016;59(2):115–21.
Rao SS.Dyssynergic defecation and biofeedback therapy.
Gastroenterol Clin North Am. 2008;37(3):569–86, viii
Rao SS, Welcher KD, Leistikow JS. Obstructive def-
ecation: a failure of rectoanal coordination. Am J Gastroenterol. 1998;93(7):1042–50.
Rao SS, Tuteja AK, Vellema T, Kempf J, Stessman
M.Dyssynergic defecation: demographics, symptoms, stool patterns, and quality of life. J Clin Gastroenterol. 2004;38(8):680–5.
Ron Y, Avni Y, Lukovetski A, Wardi J, Geva D,
Birkenfeld S, et al. Botulinum toxin type-A in ther­apy of patients with anismus. Dis Colon Rectum. 2001;44(12):1821–6.
Tantiphlachiva K, Rao P, Attaluri A, Rao SS. Digital
rectal examination is a useful tool for identifying patients with dyssynergia. Clin Gastroenterol Hepatol. 2010;8(11):955–60.

Pelvic Floor Conditions: Biofeedback

JenniferS.Beaty andCharlesA.Ternent
32
Refer toAlgorithm in Fig.32.1
Background
The internal anal sphincter is the distal (2.5–
4.0cm) condensation of the circular muscle layer of the rectum. As a smooth muscle in a state of continuous maximal contraction, the internal anal sphincter is a natural barrier to the involun­tary loss of stool and gas. The internal anal sphincter contributes 50–85% of the resting tone. The external anal sphincter is the elliptical cylin­der of striated muscle that envelops the entire length of the inner tube of smooth muscle which contributes 25% to 30% of the resting tone of the anal canal. The deepest portion of the external anal sphincter is intimately related to the puborec­talis muscle. The external anal sphincter is usu­ally inactive at rest. The external anal sphincter will contract with increased intra-abdominal pressure and rectal distension for 30–60 s. The levator ani muscle is the major component of the pelvic oor and is composed of iliococcygeus, pubococcygeus, and puborectalis muscles. The puborectalis is a strong, U-shaped loop of striated muscle that is the most medial portion of the
J. S. Beaty · C. A. Ternent (*) Section ofColon andRectal Surgery, CHI Bergan Mercy Medical Center, Creighton University School of Medicine, Omaha, NE, USA e-mail: cat@colonrectalsurgeons.com
levator ani complex. The puborectalis is respon­sible for the anorectal sling around the anorectal junction and the anorectal angle, which play roles in both continence and ability to defecate effec­tively (Table 32.1).

Pelvic Floor Dysfunction

A. Deranged pelvic oor function encompasses
a variety of conditions that often result in sig­nicantly decreased health related quality of life. Pelvic oor dysfunction or dyssynergia (PFD) is one such condition. PFD is also known as dyssynergic defecation, anismus and paradoxical anal or puborectalis contrac­tion. PFD is a common entity that can affect up to one half of patients with constipation. The etiology of PFD is not clear, but it appears to represent an acquired abnormal behavior of increased contraction of the pelvic oor and anus with strain effort that interferes with normal defecation. This failure to relax the puborectalis muscle during defecation pro­duces a functional—not a physical—obstruc­tion. Cardinal symptoms of PFD are straining at stools and sensation of incomplete evacua­tion. The diagnostic criteria for dyssynergic defecation, recently updated in the Rome III report, include those for functional constipa­tion plus at least two out of three investiga­tions (radiology, manometry and
© Springer Nature Switzerland AG 2020 S. R. Steele etal. (eds.), Clinical Decision Making inColorectal Surgery,
https://doi.org/10.1007/978-3-319-65942-8_32
245
246
J. S. Beaty and C. A. Ternent
Fig. 32.1 Algorithm for pelvic oor biofeedback; Dx diagnosis, FI fecal incontinence, SNS sacral nerve stimulation
electromyography) showing inappropriate contraction or failure to relax the pelvic oor muscles during attempts to defecate (Fig.32.2). Inadequate defecatory propulsion represents another abnormal pattern of defe­catory physiology described in the Rome III criteria (Romecriteria.org). It is associated with inadequate abdominal propulsive forces and decreased Valsalva maneuver with or without inappropriate contraction or less than 20% relaxation of the anal sphincter during attempted defecation. Fecal incontinence (FI) can also be associated with various derange­ments of pelvic oor function, including: alteration of innervation of the pelvic oor and anorectal area. In addition, anatomic injury can result in decreased anal canal tone and decreased anorectal sensation which can lead to FI.
B. A history and physical examination can
help to diagnose and guide the workup of PFD and FI. A detailed medical history should identify any ongoing issues with infrequent bowel movements, excessive straining with bowel movements and fecal incontinence. A digital rectal exam should be performed to assess appropriate contrac­tion of the anal sphincter and pelvic oor at rest, strain and squeeze. Increased anal canal tone at strain suggests the presence of PFD. Decreased anal canal tone at rest or squeeze may suggest prior anatomic or neu­rogenic injury in patients with FI.Minimal or absent abdominal Valsalva effort with strain can suggest ongoing inadequate def­ecatory propulsion issues. Anorectal physi­ology tests such as anorectal manometry (ARM), electromyography (EMG), defe-
32 Pelvic Floor Conditions: Biofeedback
Table 32.1 Biofeedback therapy components available to address specic needs of patients with outlet obstruction constipation and fecal incontinence
Fecal incontinence
Specic pathology
Regimens and exercise protocols the need to be learned and practiced
Biofeedback visualization/ resensitization modality
Therapy goal Increase anal
Neurogenic or anatomic anal sphincter compromise
Kegel type rest-squeeze cycles of varying time and attempts to maximize squeeze magnitude
ARM or EMG ARM or EMG ARM based rectal
canal tone at rest and squeeze to help minimize frequency and magnitude of FI symptoms
Pelvic oor dysfunction Decreased rectal sensation
Paradoxical/ dyssynergic defecation unlearned behavior
Pelvic oor relaxation techniques with defecation/balloon expulsion practice/ behavior modication to avoid squeeze during straining to defecate
Decrease paradoxical contraction of the pelvic oor with defecation (strain) to less than 50% of the squeeze activity
Decreased rectal call to urge from encopresis and chronic rectal stool distention or neurogenic factors
For encopresis related issues start with a bowel regimen and daily cleansing enemas. Use rectal balloon distention sensory threshold exercises with patient at decreasing volumes from urge and maximum tolerable balloon inations
balloon distention
Lower rectal volumes that are detected by patients and modify bowel patterns to help reinstate call to defecate with rectal distention
Inadequate defecatory propulsion
Decreased Valsalva maneuver with effort to defecate unlearned behavior
Increase abdominal muscle contraction and coordination of breathing patterns and posture and appropriate intra­abdominal pressure generation with strain effort to defecate
Multi-channel EMG of pelvic oor and abdominal muscles
Re-instate appropriate abdominal muscle contraction/Valsalva to generate appropriate intra-abdominal propulsion pressure for defecation while relaxing pelvic oor muscles
247
cography and balloon expulsion test can provide further evidence for the presence and magnitude of the pelvic oor problem (Fig.32.2).

Biofeedback Therapy

Biofeedback is a learning strategy that is based on “operant conditioning” and “instrumental learning” techniques. If a behavior—be it a com­plex human performance such as eating or a sim­ple physiological task such as a muscle contraction—is reinforced by intrinsic or extrin­sic means, its likelihood of being repeated increases. Miller proposed that autonomic func­tions could be regulated by the use of observable and verbal cues. A NATO conference in 1976 called for a broad range of applications for bio-
feedback. In the present practice of medicine only a few indications can be found for biofeed­back therapy and these include the management of fecal incontinence and obstructive pattern con­stipation. Interestingly, the literature suggests that optimal biofeedback treatment may be through Physical Therapy (PT) specialists as opposed to the use of devices without proper training. Also, instruction by a PT may be more effective than biofeedback alone since both modalities are mutually additive and facilitate attaining the nal desired effect. Many insurance companies will pay for pelvic oor PT, but not reimburse for biofeedback whether performed by a physical therapist, medical doctor or other allied health care provider. In order to maximize benet from biofeedback, the person administer­ing the therapy should have specialized training. PT programs teach a semester of modalities,
248
J. S. Beaty and C. A. Ternent
Fig. 32.2 High resolution anorectal manometry showing lack of relaxation of the pelvic oor with strain in a patient with paradoxical puborectalis activity
including 5–10h on the basic use and interpreta­tion of biofeedback. Specic pelvic oor training can be obtained from the Section on Women’s Health of the American Physical Therapy Association which offers a level 1, 3-day course consisting of approximately 4 additional hours of instruction specic to interpreting and instructing biofeedback for pelvic oor disorders (http://
www.womenshealthapta.org/2017livecourses/).
The Biofeedback Certication International Alliance (BCIA) (http://www.bcia.org) certies non-physical therapy providers to use biofeed­back (RNs, MDs, Massage Therapists, Psychologists, etc.). A trained professional should be able to detect subtle yet important sub­stitutions by patients with ancillary muscles (i.e., gluteus muscles) during pelvic oor muscle bio­feedback. In addition, a trained professional
32 Pelvic Floor Conditions: Biofeedback
249
should be able to recognize if muscle fatigue is occurring during a treatment session and use this as a signal to stop the biofeedback session prema­turely to avoid muscle overuse. There are also differences between the exercises instructed for strengthening (concentric contractions) versus downtraining (eccentric contractions) used for outlet obstructions and pelvic oor pain and ten­sion patterns, respectively. Also, there are differ­ent bers that may be recruited with short quick icks versus long holds. Optimal pelvic oor bio­feedback is therefore, a complicated proposition that entails both directed physical therapy and visualization biofeedback techniques to help improve function. The quality of results with bio­feedback depends on the skill of the individual directing the biofeedback and the dedication of the patient to the program.
C. Sensory training was the rst biofeedback
technique used in clinical practice. It entails simulated defecation by means of a water­lled balloon introduced into the rectum. The balloon is slowly withdrawn while patients are asked to concentrate on the rectal sensation evoked by the balloon and attempt expulsion. Variations of this technique involve defecation of a balloon or simulated stools to improve defecatory dynamics. This technique of rectal resensitization and facilitation of rectal evacu­ation using biofeedback may be especially useful in patients with decreased rectal sensa­tion, encopresis related outlet dysfunction, PFD and rectal inertia. It can also be used in patients with FI with decreased rectal sensa­tion. We routinely add a bowel regimen with a high/low ber diet and laxatives/anti- motility agents as needed to promote regular bowel habits. We also employ strategic use of ene­mas to the sensory biofeedback technique in order to help reinstate the physiologic call to urge that may have been lost. Behavior modi­cation also forms an integral part of treat­ment for encopresis patients who have lost rectal sensation and the call to defecate as a result of chronic abnormal rectal content retention. The balloon expulsion test with the ability to gradually increase expulsion vol-
umes provides valuable information on the progress with rectal sensation and evacuation.
The 2016 American Society of Colon and Rectal Surgery Practice Parameters for the Clinical Practice Guidelines for the Evaluation and Management of Constipation recommend biofeedback as the main form of therapy for dys­synergic defecation with 1B evidence grading, corresponding to a strong recommendation with moderate quality evidence and benets that clearly outweigh risks and burdens. A prospec­tive randomized trial investigated the efcacy of biofeedback (manometric-assisted anal relax­ation, muscle coordination, and simulated defe­cation training biofeedback) with either sham feedback therapy or standard therapy (diet, exer­cise, and laxatives) in 77 subjects (69 women) with chronic constipation and dyssynergic defe­cation. At baseline and after 3months of treat­ment, physiologic changes were assessed by anorectal manometry, balloon expulsion, and colonic transit study, and symptomatic changes and stool characteristics were recorded using a visual analog scale and prospective stool diary. Subjects in the biofeedback group were more likely to correct their dyssynergia, improve def­ecation indexes, and decrease balloon expulsion time. Colonic transit improved after biofeedback or standard therapy but not after sham therapy. Biofeedback increased the number of complete spontaneous bowel movements and decreased the use of digital maneuvers and was associated with higher global bowel satisfaction. In this study, biofeedback relieved constipation and improved physiologic bowel function in patients with dyssynergia. A high pretreatment constipa­tion symptom score, a high rectal sensory thresh­old, and a delayed colonic transit time have been associated with poor biofeedback treatment out­comes for PFD.
Hardware requirements for biofeedback train­ing are variable and dependent on patient and provider preference and availability. The posi­tioning of the patient should be that which most comfortably allows optimal visualization of the biofeedback tracings by the patient. One descrip­tion of EMG biofeedback for PFD involves