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- •Foreword
- •Preface
- •Second Edition Clinical Decision Making
- •Acknowledgments
- •Contents
- •Editors and Contributors
- •Editors
- •Contributors
- •Refer to Algorithm in Fig. 1.1
- •Conclusion
- •Suggested Reading
- •1: Anorectal Examination
- •Suggested Reading
- •3: Physiologic Testing
- •Refer to Algorithm in Fig. 3.3
- •Suggested Reading
- •Refer to Algorithm in Fig. 4.1
- •Single Center Studies
- •Special Considerations
- •Low Rectal or Coloanal Anastomosis
- •Multi-center Studies
- •Suggested Reading
- •Summary
- •Suggested Reading
- •Introduction
- •Refer to Algorithm in Fig. 6.1
- •Minimally Invasive Colorectal Surgery
- •Intraoperative Fluid Administration
- •Analgesia
- •Venous Thromboembolism Prophylaxis
- •Surgical Site Infection Prevention
- •Postoperative Analgesia
- •Intravenous Fluid Management
- •Early Oral Feeding
- •Early Ambulation
- •Conclusion
- •Suggested Reading
- •Refer to Algorithm in Fig. 7.1
- •Refer to Algorithm in Fig. 7.2
- •Melena Caused by Upper Gastrointestinal Bleeding
- •Hematochezia Caused by Anorectal Bleeding
- •Severe Hematochezia Causing Hemodynamic Instability
- •Suggested Reading
- •Suggested Reading
- •Suggested Reading
- •10: Anal Conditions: Anal Fissure/Recurrent Anal Fissure
- •Suggested Reading
- •Suggested Reading
- •12: Anorectal Abscess
- •Suggested Reading
- •13: Anal Conditions: Fistula-in-Ano
- •Suggested Reading
- •14: Anal Conditions: Rectovaginal Fistula
- •Refer to Algorithm in Fig. 14.1
- •Background
- •Etiology
- •Evaluation
- •Treatment
- •Ileoanal Pouch-Vaginal Fistulas
- •Vaginal Approaches
- •Conclusion
- •Suggested Reading
- •15: Anal Conditions: Anorectal Crohn’s Disease—Fistula
- •Introduction
- •Conclusion
- •Suggested Reading
- •Suggested Reading
- •Suggested Reading
- •18: Anal Conditions: External Hemorrhoids
- •Introduction
- •Refer to Algorithm in Fig. 18.4
- •Suggested Reading
- •Refer to Algorithm in Fig. 19.1
- •D. Hair Removal
- •Suggested Reading
- •20: Anal Conditions: Pruritus Ani
- •Suggested Reading
- •21: Anal Conditions: Hidradenitis Suppurativa
- •Suggested Reading
- •22: Anal Conditions: Anorectal Trauma
- •Suggested Reading
- •23: Anal Conditions: STDs
- •Refer to Algorithm in Fig. 23.1
- •Anal Conditions: Sexually Transmitted Diseases
- •Suggested Reading
- •24: Anal Considerations: Fournier’s Gangrene
- •Refer to Algorithm in Fig. 24.1
- •Suggested Reading
- •25: Non-healing Perineal Wounds
- •Suggested Reading
- •26: Anal Intraepithelial Neoplasms
- •Diagnoses
- •Suggested Reading
- •27: Anal Conditions: Anal Margin Tumors
- •Suggested Reading
- •28: Invasive Anal Canal Neoplasia
- •Suggested Reading
- •29: Pelvic Floor Conditions: Rectal Prolapse/Recurrence
- •Suggested Reading
- •30: Pelvic Floor Conditions: Rectal Intussusception
- •Suggested Reading
- •31: Pelvic Outlet Obstruction
- •Suggested Reading
- •32: Pelvic Floor Conditions: Biofeedback
- •Background
- •Pelvic Floor Dysfunction
- •Biofeedback Therapy
- •Suggested Reading
- •33: Pelvic Floor Conditions: Fecal Incontinence
- •Fiber Supplementation
- •Medications
- •Biofeedback
- •End-to-End Sphincteroplasty
- •Tibial Nerve Stimulation
- •Graciloplasty
- •Gluteoplasty
- •∗Other Therapies
- •Injectables
- •RF Remodeling
- •Conclusion
- •Suggested Reading
- •34: Pelvic Floor Conditions: Diarrhea
- •Refer to Algorithm in Fig. 34.1
- •Suggested Reading
- •35: Chronic Constipation
- •Introduction
- •Diagnosis
- •Management
- •Suggested Reading
- •36: Retrorectal Tumors
- •Evaluation
- •Risk Assessment
- •Pathology: Four Tissue Types
- •Treatment
- •Suggested Reading
- •37: Rectal Cancer: Local Therapy
- •Suggested Reading
- •38: Rectal Conditions: Rectal Cancer—Proctectomy
- •Suggested Reading
- •39: Rectal Conditions: Rectal Cancer—Adjuvant and Neoadjuvant Therapy
- •Refer to Algorithm in Fig. 39.1
- •Suggested Reading
- •40: Rectal Conditions: Stage IV Rectal Cancer
- •Introduction
- •Refer to Algorithm in Fig. 40.1
- •Suggested Reading
- •Refer to Algorithm in Fig. 41.1
- •Suggested Reading
- •42: Rectal Conditions: Rectal Cancer—Postoperative Surveillance
- •Suggested Reading
- •43: Recurrent Rectal Cancer
- •Introduction
- •Refer to Algorithm in Fig. 43.2
- •A–C.
- •Carbon-Ion Radiation (CIRT)
- •Conclusion
- •Suggested Reading
- •44: Locally Advanced Rectal Cancer
- •Suggested Reading
- •45: Colonic: Diverticulitis
- •Refer to Algorithm in Fig. 45.1
- •Suggested Reading
- •46: Colonic Conditions: Large Bowel Obstruction
- •Suggested Reading
- •47: Colonic Conditions: Volvulus
- •Refer to Algorithm in Fig. 47.1
- •Introduction
- •Suggested Reading
- •48: Colonic Stricture
- •Suggested Reading
- •49: Acute Colonic Pseudo-Obstruction (ACPO): Ogilvie’s Syndrome
- •Suggested Reading
- •50: Colonic Conditions: Irritable Bowel Syndrome (IBS)
- •Introduction
- •Suggested Reading
- •51: Colorectal Trauma
- •Suggested Reading
- •52: Endometriosis
- •Suggested Reading
- •53: Colonic Conditions: Ulcerative Colitis
- •Conclusions
- •Suggested Reading
- •54: Colonic Conditions: Indeterminate Colitis
- •Suggested Reading
- •55: Colonic Conditions: Toxic Colitis
- •Medical Management
- •Risk Assessment
- •Surgical Management
- •Suggested Reading
- •56: Crohn’s Colitis
- •Suggested Reading
- •57: Ischemic Colitis
- •Suggested Reading
- •58: Colonic Conditions: Infectious Colitis
- •Suggested Reading
- •59: Colonic Conditions: Benign Colonic Neoplasia
- •Suggested Reading
- •60: Familial Adenomatous Polyposis
- •Suggested Reading
- •61: Colonic Conditions: Lynch Syndrome
- •Suspected Lynch Syndrome
- •Lynch Syndrome Diagnosis Without Clinical Symptoms or Phenotype
- •Suggested Reading
- •62: Malignant Colon Polyps
- •Suggested Reading
- •63: Colonic Conditions: Adenomatous Polyps
- •Suggested Reading
- •64: Colon Cancer Surgical Therapy
- •Suggested Reading
- •65: Colonic Conditions: Locally Advanced Colon Cancer
- •Conclusion
- •Suggested Reading
- •66: Recurrent Colon Cancer
- •Suggested Reading
- •67: Appendiceal Neoplasms

18 Anal Conditions: External Hemorrhoids
149
for ofce-based procedures such as banding
for external hemorrhoids. Excisional hemorrhoidectomy or excision of anal skin tags
should be performed in the operating room.
An honest conversation regarding the postoperative pain and potential complications
including damage to sphincter muscles or
anal stricture or recurrent skin tags is necessary before the patient should agree to
surgery. Also, if the patient’s symptoms do
not correlate with your exam ndings, be
wary about improving their symptoms with
surgery and look for other causes.
Excisional hemorrhoidectomy can be performed under general anesthesia or with a
spinal block. This procedure should be performed in prone position. Sharp dissection,
cautery, or advanced energy devices can be
utilized for excision and these wounds can
be closed or left open to heal by secondary
intention. Postoperative pain control is
improved with the use of long-acting local
anesthetic and vigilant bowel regimen.
Suggested Reading
Hall JF. Modern management of hemorrhoidal disease.
Gastroenterol Clin N Am. 2013;42(4):759–72.
Khubchandani I, Paonessa N, Khawaja A. Surgical treat-
ment of hemorrhoids. London: Springer Verlag; 2009.
Lohsiriwat V. Treatment of hemorrhoids: a colo-
proctologist’s view. World J Gastroenterol.
2015;21(31):9245–52.
Rivadeneira D, Steele S, Ternent C, Chalasani S, Buie D,
Rafferty J. Practice parameters for the management
of hemorrhoids (revised 2010). Dis Colon Rectum.
2011;54(9):1059–64.
Sanchez C, Chinn B. Hemorrhoids. Clin Colon Rectal
Surg. 2011;24(1):5–13.

Anal Conditions: Pilonidal Disease/
Complex andRecurrent Pilonidal
Disease
RichardS.Hoehn andIanM.Paquette
19
Refer to Algorithm in Fig. 19.1
A.History andPresentation
Pilonidal disease affects 0.7% of the population,
usually between the ages of 15 and 30, and is
twice as common in men than women. Risk factors include having thick or hairy skin, increased
sweating, a deep gluteal cleft, poor hygiene,
obesity, and prolonged periods of sitting. It is
generally accepted that this disease originates
from traumatization of hair follicles in the natal
cleft which leads to inammation and a granulomatous foreign body-type reaction, which is
exacerbated by the warm, moist, high-friction
environment of this region. These conditions
can lead to formation of an abscess or stulous
tracts. Clinical presentation is quite varied and
can range from the presence of asymptomatic
midline pits noted on physical examination to a
complex network of draining sinus tracts, which
can result in a debilitating decrease in quality of
life. The most common initial presentation is
pain and intermittent discharge, occasionally
R. S. Hoehn
Department ofSurgery, University ofCincinnati,
Cincinnati, OH, USA
I. M. Paquette (*)
Division ofColon andRectal Surgery, Department
ofSurgery, University ofCincinnati Medical Center,
Cincinnati, OH, USA
e-mail: paquetin@UCMAIL.UC.EDU
with bleeding, from one, or many sinus tracts in
the gluteal cleft.
B.Physical Examination
Diagnosis of pilonidal disease is straightforward
and requires no imaging or testing. Physical
examination will reveal one or several pits in the
midline gluteal cleft. Patients may present with
an acute abscess or a chronically draining sinus
(Fig. 19.2). When present, abscesses in this
region tend to present lateral to the midline
(Fig.19.3). The pilonidal cyst or sinus is usually
found near midline at the top of the gluteal cleft,
approximately 4–10 cm from the anus. The
infected sinus is usually accompanied by other
pits that communicate with the deeper cavity by
an epithelized tract. It is important to differentiate pilonidal disease from other diagnoses such
as hidradenitis suppurativa, Crohn’s disease,
perianal stula, and other infectious processes.
One major difculty is assessing the degree of
active disease below the skin. A common situation encountered is that the degree of extension
under the skin can be much more extensive than
it may appear based upon examination in the
ofce. The surgeon must be aware of this possibility if operative intervention is to be offered.
Patients may also present with chronic pilonidal
disease with a range of severity. Some patients have
minimally symptomatic sinus tracts that may be
treated with hair removal and potentially phenol
© Springer Nature Switzerland AG 2020
S. R. Steele etal. (eds.), Clinical Decision Making in Colorectal Surgery,
https://doi.org/10.1007/978-3-319-65942-8_19
151

152
R. S. Hoehn and I. M. Paquette
A. History
and
presentation
B. Physical
exam
Fig. 19.1 Algorithm for treatment of pilonidal disease
Pilonidal
disease without
abscess
Aute pilonidal
abscess
Minimally
symptomatic
Symptomatic
Recurrent
disease
C. Incision
and drainage
D. Hair removal
E. Phenol
injection
F. Excision and
primary repair
G. Excision healing
by secondary
intention
H. Flap-based
procedures
injection. Some patients have chronic and symptomatic disease that requires excision with healing
by primary intention, secondary intention, or a certain ap-based procedures if a deep cleft is found
(cleft lift or Karydakis, below). These patients
would benet from hair removal as well (Fig.19.3).
C.Incision andDrainage Only
For acute presentations with an abscess, whether
primary or recurrent, incision and drainage is
indicated. Using local anesthesia, a 1cm cruciate
incision is made close to midline and skin aps
are excised. Drainage is performed lateral to the
midline. Drains or packing are not routinely indicated, and current literature does not support the
use of antibiotics. Incision and drainage alone
has a recurrence rate of >40%. Based upon the
relatively high recurrence rate, patients are
offered options including expectant follow-up,
hair removal, or elective excision. Shaving of the
area along with careful attention to hygiene may
be benecial in preventing recurrences.
D.Hair Removal
As pilonidal disease likely develops from hair
follicle ingrowth, hair removal techniques have
been shown to reduce the need for surgical
intervention as well as disease recurrence when
used either as an adjunct to surgical management. Therefore, hair removal can be considered for all patients presenting with current or
past symptomatic pilonidal disease. Shaving
has been the preferred treatment modality, and
while laser hair removal has garnered much
interest, data supporting this technique are
insufcient to support routine use. This should
be performed in conjunction with meticulous
hygiene.

ab
19 Anal Conditions: Pilonidal Disease/Complex andRecurrent Pilonidal Disease
153
c
Fig. 19.2 Patient presenting with chronic pilonidal sinus in
the gluteal cleft (With permission from Johnson EK.Pilonidal
Disease and Hidradenitis Suppurativa. In: Steele SR, Hull
E.Phenol Injection
Phenol injection is a potential non-operative
adjunct to treatment that is less commonly
used. To whatever extent possible, tracts should
be debrided free of any excess hair or debris
and curetted to remove excessive granulation
tissue. Under a local anesthetic block, the
injection of 1–2 mL of 80% phenol solution
TL, Read TE, Saclarides TJ, Senagore AJ, Whitlow CB, editors. The ASCRS Textbook of Colon and Rectal Surgery, 3rd
ed. Springer, NewYork; 2016:pp: 289–307 © Springer)
causes epithelial destruction and intense
inammation that has a 60–95% success rate
at closing pilonidal tracts. This therapy induces
signicant discomfort and may require inpatient admission for pain control. This treatment
is best reserved for patients with limited sinus
tracts and mild to moderate symptoms from
their pilonidal disease.

154
Fig. 19.3 Pilonidal abscess presenting to the left of the midline (With permission from Johnson EK.Pilonidal Disease
and Hidradenitis Suppurativa. In: Steele SR, Hull TL, Read
TE, Saclarides TJ, Senagore AJ, Whitlow CB, editors. The
ASCRS Textbook of Colon and Rectal Surgery, 3rd ed.
Springer, NewYork; 2016:pp: 289–307. © Springer)
F.Excision andPrimary Repair
Patients with chronic, symptomatic pilonidal
disease may benet from excision of the diseased tissue. Excision of the pilonidal abscess
and tracts followed by primary surgical repair
has led to faster healing rates than healing by
secondary intention in multiple prospective,
randomized trials. However, primary closure
may be associated with increased rates of recurrent disease. When primarily closing wounds in
this area it is important to leave the surgical
wound off the midline. Additionally, it is important to excise only the tissue involved with the
sinus tracts rather than excising down to the
fascia, encompassing large amounts of normal
tissue. This unnecessary step creates a large
deadspace and leads to complications in healing. Midline surgical wounds, and large volume
excisions, have been independently associated
with delayed wound healing following primary
closure. A meta-analysis found that off-midline
closures had a lower failure rate (3–5% versus
R. S. Hoehn and I. M. Paquette
9%) and recurrence rate (1–3% versus 9.5%)
compared to midline closure. Drain placement
in this setting has demonstrated improved healing with no effect on disease recurrence, though
it is only like necessary in the setting of a larger
volume excision leaving signicant deadspace.
In scenarios with smaller volume excisions, a
layered primary closure will sufce.
G.Excision andHealing by Secondary
Intention
For patients with a substantial excision, or those
who have failed primary closure, excision and
healing with secondary intention is a potential
next step. For acute or recurrent disease, curettage of the abscess cavity may improve healing
and lower recurrence rates. It is important to
adhere to sound principles when performing this
procedure. The goals are to eradicate the subcutaneous sinus tracts and remove any excessive
granulation tissue and debris. Opening the tracts
over a stula probe and injection of small quantities of methylene blue into the tracts can be
helpful adjuncts to achieving these goals. If
these principles are adhered to, the disease can
often be excised without creating excessively
large soft tissue defects. Marsupialization of the
wound edges may reduce the wound to a more
manageable size and precipitate quicker healing. In the event of a larger excision, negative
pressure wound therapy has shown promise as
an adjunctive treatment for complex, recurrent
pilonidal disease, but current literature has yet
to dene a clear role for this therapy. If this type
of procedure is planned, the patient must be
counseled on the expected prolonged period of
time to achieve complete healing.
H.Flap-Based Procedures
For patients with complex pilonidal disease or
recurrent disease following basic excision and
closure, ap-based closure should be considered.
There are multiple ap procedures, each with a
recurrence rate of <10%.

19 Anal Conditions: Pilonidal Disease/Complex andRecurrent Pilonidal Disease
155
Fig. 19.4 The Bascom or cleft-lift technique starts with
marking a “safe zone” prior to surgery (With permission
from Johnson EK. Pilonidal Disease and Hidradenitis
Suppurativa. In: Steele SR, Hull TL, Read TE, Saclarides
TJ, Senagore AJ, Whitlow CB, editors. The ASCRS
Textbook of Colon and Rectal Surgery, 3rd ed. Springer,
NewYork; 2016:pp: 289–307. © Springer)
Cleft elevating procedures such as the
Karydakis and Bascom procedures, can be considered as rst-line surgical treatment for individuals with a very deep gluteal cleft, or in cases
of recurrent pilonidal disease. The technical
challenge lies in elevating the distal most aspect
of the gluteal cleft, and the incision is often
curved in the inferior location to account for
this. Groups have published very low complication and recurrence rates with each technique,
and practitioners should choose a technique
based on experience and comfort with the
procedure.
The Karydakis ap involves a midline excision of the pilonidal tracts and diseased tissue
with creation of an elliptical defect. The excision favors the more diseased side, with preservation of normal tissue on the contralateral side
to use as a ap. Next, a beveled ap is created
from the more medial tissue and is sutured later-
Fig. 19.5 To help rotate the distal portion of the wound to
a lateral position, a scimitar shape is used on the distal incision (With permission from Johnson EK.Pilonidal Disease
and Hidradenitis Suppurativa. In: Steele SR, Hull TL, Read
TE, Saclarides TJ, Senagore AJ, Whitlow CB, editors. The
ASCRS Textbook of Colon and Rectal Surgery, 3rd ed.
Springer, NewYork; 2016:pp: 289–307. © Springer)
ally to the sacrococcygeal fascia to avoid midline tension, followed by an off-midline skin
closure. This technique has a wound complication rate of 8% and recurrence rate of 2%.
Advantages include a tension- free closure that
is off-midline as well as attening of the natal
cleft. It is also one of the easier ap procedures
to perform.
The Bascom or cleft-lift technique is a simple but intricate procedure that is designed to lift
the natal cleft and provide an off- midline closure. Prior to surgery, a “safe zone” is marked
on the skin to indicate the limits of dissection
(Fig.19.4). The buttocks are taped apart and a
triangular incision is made with the apex above
and lateral to the cleft. The distal portion of the
incision is scimitar shaped in order to facilitate
closure near the anus (Fig. 19.5). The ap is

156
R. S. Hoehn and I. M. Paquette
Fig. 19.6 The Limberg or rhomboid ap involves excision of all diseased tissue in the midline in a diamond- or
rhomboid-shaped block (With permission from Johnson
EK.Pilonidal Disease and Hidradenitis Suppurativa. In:
Steele SR, Hull TL, Read TE, Saclarides TJ, Senagore AJ,
Whitlow CB, editors. The ASCRS Textbook of Colon and
Rectal Surgery, 3rd ed. Springer, New York; 2016:pp:
289-307. © Springer)
raised with care to leave the subcutaneous fat in
place. The skin ap is excised, hair and granulation tissue debrided, and the ap is sutured over
a drain. Recurrence rates are around 4%. This
procedure is not ideal for patients with complex
recurrent disease, large wounds, and disease
close to the anus.
Rotational aps are more involved procedures
and generally second-line therapy for patients
with multiple-recurrent or very extensive disease.
The Limberg or rhomboid ap involves midline excision of the pilonidal disease, with a diamond- or rhomboid-shaped incision, (Fig.19.6)
down to the presacral fascia and rotational fasciocutaneous coverage. The ap must be of the same
thickness as the excised tissue, and closure is
with layered absorbable sutures and closed-suction drain (Fig.19.7). Recurrence rates with this
procedure are 0–6%, the same as the wound complication rates, which may include hematoma or
seroma formation as well as areas of minor
wound separation due to tension closure. This is
a preferred procedure in the setting of complex
recurrent disease. However, due to the complex-
Fig. 19.7 Completed Limberg ap (With permission
from Johnson EK. Pilonidal Disease and Hidradenitis
Suppurativa. In: Steele SR, Hull TL, Read TE, Saclarides
TJ, Senagore AJ, Whitlow CB, editors. The ASCRS
Textbook of Colon and Rectal Surgery, 3rd ed. Springer,
NewYork; 2016:pp: 289–307. © Springer)
ity of the procedure, a surgeon must either have
extensive experience with this technique, or collaborate with a plastic surgeon who is well versed
in this technique. The V-Y advancement ap and
the Z-plasty, both of which report >90% healing
and low disease recurrence, are other closure
options for wide excision of complex disease.
However, the V-Y ap uses a midline closure,
often over a drain, and both are considered inferior to the above techniques.
Suggested Reading
de Parades V, Bouchard D, Janier M, Berger A.
Pilonidal sinus disease. J Visc Surg. 2013;150(4):
237–47.
Farrell D, Murphy S. Negative pressure wound ther-
apy for recurrent pilonidal disease: a review of
the literature. J Wound Ostomy Continence Nurs.
2011;38(4):373–8.
Harris CL, Laforet K, Sibbald RG, Bishop R. Twelve
common mistakes in pilonidal sinus care. Adv Skin
Wound Care. 2012;25(7):324–32; quiz 33–4
Humphries AE, Duncan JE. Evaluation and manage-
ment of pilonidal disease. Surg Clin North Am.
2010;90(1):113–24, Table of Contents

19 Anal Conditions: Pilonidal Disease/Complex andRecurrent Pilonidal Disease
157
Johnson EK.Pilonidal disease and hidradenitis suppura-
tiva. In: Steele SR, Hull TL, Read TE, Saclarides TJ,
Senagore AJ, Whitlow CB, editors. The ASCRS textbook of colon and rectal surgery. 3rd ed. NewYork:
Springer International Publishing; 2016.
Mavros MN, Mitsikostas PK, Alexiou VG, Peppas G,
Falagas ME.Antimicrobials as an adjunct to pilonidal
disease surgery: a systematic review of the literature.
Eur J Clin Microbiol Infect Dis. 2013;32(7):851–8.
Steele SR, Perry WB, Mills S, Buie WD, Surgeons
SPTFotASoCaR. Practice parameters for the management of pilonidal disease. Dis Colon Rectum.
2013;56(9):1021–7.
Vahedian J, Nabavizadeh F, Nakhaee N, Vahedian M,
Sadeghpour A. Comparison between drainage and
curettage in the treatment of acute pilonidal abscess.
Saudi Med J. 2005;26(4):553–5.

Anal Conditions: Pruritus Ani
BrianL.Bello andKonstantinUmanskiy
20
Refer to Algorithm in Fig.20.1
A. The urge to itch in pruritus ani is mediated by
the extensive, unmyelinated C-bers that are
predominant in the anoderm and perianal
skin. Stimulation of these bers leads to
scratching and frequent wiping in order to
relieve the urge. This often contributes to
excoriation and cutaneous injury, which
causes additional stimulation of the C-bers,
inciting more itching and scratching. This
may ultimately lead to a self-defeating
vicious cycle (Fig. 20.2). Pruritus ani is
reported to affect up to 5% of the population.
The condition is more common in men than
women with a 2:1 ratio. It is usually seen in
older adults but can affect people of any age.
Refractory cases have been described and
can lead to severe physical and emotional
distress.
B. A thorough history must be obtained as this
often gives clues as to the likely cause of
itching. Specic aspects of the history should
include the following:
B. L. Bello
Department ofColorectal Surgery Program, MedStar
Washington Hospital Center, Washington, DC, USA
K. Umanskiy (*)
Department ofSurgery, University ofChicago,
Chicago, IL, USA
e-mail: kumanskiy@surgery.bsd.uchicago.edu
• Bowel habit: frequency, constipation,
incomplete evacuation, diarrhea, seepage,
stool consistency, change in stool caliber.
• Diet: coffee, chocolate, spicy foods, dairy,
citrus, tomatoes; request food journal.
• Toileting behavior and hygiene: time on
toilet, straining, types of wipes, method of
wiping, cleansing agents.
• Local irritants: creams, wipes, undergarments tight-tting or synthetic material
undergarments, anal moisture.
• Systemic signs: abdominal pain, weight
loss, fevers, fatigue.
• Past medical history: diabetes, dermatologic conditions, malignancy, sexual practices, gastrointestinal disorders, radiation,
sexually transmitted diseases, previous
anorectal surgery.
A careful external evaluation should be
performed noting the severity and extent
of any inammation or skin changes.
Masses, irregularity, and induration
should be assessed by digital anorectal
examination. Anoscopy may reveal abnormalities in the anal and distal rectal
mucosa and help to identify or exclude
anorectal causes of itching, including
hemorrhoids, anal ssure, and stula-inano. While there is no specic diagnostic
laboratory test for pruritus ani, an HIV
test can be benecial and a CBC may suggest an infectious or malignant process.
© Springer Nature Switzerland AG 2020
S. R. Steele etal. (eds.), Clinical Decision Making in Colorectal Surgery,
https://doi.org/10.1007/978-3-319-65942-8_20
159

160
B. L. Bello and K. Umanskiy
Fig. 20.1 Algorithm for diagnosis and treatment of pruritus ani
C. Biopsy is an indispensable modality for evalua-
Stimulation
of C-fibers
Scratching,
Wiping
D. In up to 75% of cases of pruritus ani, an identi-
Itching,
Irritation
Fig. 20.2 Pruritus ani: a vicious cycle
Cutaneous
injury
tion of anal itching. Any abnormal appearing
lesion or perianal skin changes should be biopsied. This can easily be done in the ofce setting with local anesthetic and a 15-blade scalpel
or punch biopsy. Endoscopy is a useful adjunct
to perianal biopsy and should be performed to
rule out malignancy especially if the patient is
older or has concerning symptoms such as
abdominal pain, weight loss, change in bowel
movements, or blood in the stool.
able etiology can be found. While there are
dozens of conditions associated with anal itching, most of them can be classied as infectious, dermatologic, systemic, local irritants, or
colorectal- and anal-specic causes (Fig.20.1).
Here, we will review the most common causes.
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