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Grade 0 (UTD P1) Grade 1 (UTD P1) Grade 2 (UTD P2) Grade 3 (UTD P3) Grade 4 (UTD P3)
43 Obstructive Uropathy
Table 43.4 Urinary tract dilation (UTD) classication system
Anterior-posterior renal pelvic diameter (APRPD) Major calyceal dilation Yes/no Minor calyceal dilation Yes/no Parenchymal thickness Normal/abnormal Parenchymal appearance Normal/abnormal Evaluate for heterogeneity or cysts Ureters Normal/abnormal Bladder Normal/abnormal Evaluate for ureteroceles and bladder thickness Grades UT P1 (low risk) Central calyceal dilation only or low-risk APRPD based on age, normal
Measured at the largest diameter of the renal pelvis
parenchyma/ureters/bladder UT P2 (intermediate risk) UT P3 (high risk) UT P2 with parenchymal or bladder abnormalities
Peripheral calyceal dilation and/or abnormal ureter ± central calyceal dilation ±
intermediate APRPD, normal parenchyma and bladder
479
Fig. 43.1 Depiction of the Society of Fetal Urology grading of hydronephrosis in the sagittal plane. For comparison, the urinary tract dilation
classication system approximate corresponding grade is in parenthesis
appearance can be lost. US can also be useful for detecting

Conventional Therapy

debris, stones, or gas within the renal collecting system. Evaluation of the ureters on ultrasound can be limited sec­ondary to patient body habitus and bowel gas.
Non-contrast cross-sectional CT imaging has become a mainstay in the initial evaluation of many abdominal condi­tions and is excellent at not only assessing for the presence of
Indications for treatment will vary based on the underlying cause of the hydronephrosis, patient’s symptoms, and extent of acute renal injury. Conventional therapies for hydrone­phrosis aim to correct the underlying cause of the
hydronephrosis. hydronephrosis but very sensitive (97%), specic (96%), and accurate (97%) for the evaluation of urolithiasis [17]. One important limitation of CT is the limited ability to detect
Urolithiasis
indinavir and pure matrix stones due to low X-ray beam attenuation [18, 19]. If the patient’s renal function is ade­quate to support IV contrast, delayed contrast-enhanced images (CT urogram) can evaluate the anatomy and patency of the collecting system, assess urothelial thickness which can indicate inammation or malignancy, and differentiate complete from partial obstructions in the setting of hydronephrosis.
Acute management of a urinary tract stone is based on the
stone’s size, location, presence or absence of associated
hydronephrosis, and extent of renal function loss which is
based on the best practice guidelines of the American Urologic
Association (AUA) [20]. Invasive procedures for stones are
typically performed when the urinary tract is sterile; treat-
ment of any UTI should be attempted prior to intervention.
480
Key Point
Any associated UTI should be treated rst prior to intervention so as not to disseminate the infection.
Medical therapy generally consists of pain control and alpha blocker therapy to assist in passing a stone which can be considered when ureteral stones are less than 10mm or when there are symptomatic non-obstructing renal pelvis stones. The time course for spontaneously passing a stone will vary based on size and location, taking up to 1month for larger more proximal stones [21]. If a stone fails to pass after 4–6 weeks or if there is clinical decline, more denitive options may be considered. Active surveillance is recom­mended with non-obstructing asymptomatic calculi.
Shockwave lithotripsy or ureteroscopic lithotripsy can be used to treat ureteral stones >10mm, lower pole stone burden <10mm, or non-lower pole stone burden >20mm. While ureteroscopy is a more invasive with higher chance of urothelial injury, it offers a greater chance of stone removal.
Percutaneous nephrostolithotomy (PCNL) may be offered for larger kidney stones (>10mm) that would not be ade­quately treated with lithotripsy and when there is signicant residual kidney function to justify the procedure. PCNL, as the name implies, involves using percutaneous access to place a nephroscope into the collecting system. While PCNL allows greater visualization of the calyces and a greater chance of stone removal, there is increased risk of complica­tions including hemorrhage compared with shockwave or ureteroscopic lithotripsy [20, 22, 23].
Key Point
Percutaneous nephrostolithotomy is indicated for renal calculi >10mm which could not be adequately treated with lithotripsy.
Nephrectomy may be offered when there is limited resid­ual kidney function and the affected kidney is causing persis­tent pain or recurrent infection. Residual kidney function is typically evaluated with a nuclear medicine scan such as a MAG3 scan which allows differential of the renal function per kidney. Contralateral kidney function should be assessed prior to performing a nephrectomy.
Infection
UTIs without a specic nidus for infection are typically managed with antibiotics. The most common causative
L. A. Byers and P. J. Rochon
organism is Escherichia coli, and common empiric therapy includes trimethoprim-sulfamethoxazole (Bactrim) and nitrofurantoin (Macrobid). A special case to consider is emphysematous pyelonephritis, which is seen almost exclusively in diabetics. This was historically treated with a combination of antibiotics and nephrectomy; however, more recent research demonstrates signicantly decreased mortality with a combination of antibiotic therapy and percutaneous drainage [24].
Key Point
Emphysematous pyelonephritis = Severe infection with gas forming around the kidney. Treatment includes antibiotics and percutaneous drainage, rarely nephrectomy.
BPH
Patients that exhibit uncomplicated LUTS may be managed medically with alpha blockers, 5-alpha-reductase inhibitors, and/or anticholinergics. When symptoms become more bothersome or if complications of BPH (renal injury, recur­rent urinary infections, bladder stones, or hematuria) are present, invasive procedures such as transurethral resection of the prostate (TURP) or prostatectomy may be considered [25]. Long-term complications of these procedures include retrograde ejaculation, erectile dysfunction, and inconti­nence. An innovative new IR treatment for BPH consists of prostatic artery embolization (refer to Chap. 29 for more information).
Urothelial Carcinoma
Treatment will depend on the location of the lesion within the urinary tract and the depth of invasion. Approximately 90–95% of urothelial cancer will occur in the bladder with the upper tract lesions occurring in less than 5% of cases; however, 22–47% of patients with a primary upper tract lesion will develop a “drop” metastasis to the bladder [26]. For bladder tumors that do not invade the muscularis layer, local treatment with transurethral resection of bladder tumor (TURBT) and/or intravesicular instillation of inactivated mycobacterium bovis (BCG) is the rst line treatment. Tumors which invade the muscularis may be treated with TURBT, radiation, neoadjuvant/adjuvant chemotherapy, and/or radical cystectomy with urinary diversion. Treatment for upper tract urothelial carcinoma includes nephrectomy, nephroureterectomy, segmental ureterectomy, and endo­scopic resection of the tumor.
43 Obstructive Uropathy
Neurogenic Bladder
Most patients with urinary retention secondary to a neuro­genic bladder are managed with a combination of cholinergic medications such as bethanecol and intermittent catheteriza­tion. Patients that are unable to self-catheterize may require indwelling catheters, although this poses an increased risk of UTIs. In refractory cases, surgical sphincterotomy can be per­formed; however, this may cause urinary incontinence.

Interventional Therapy

Percutaneous nephrostomy (PCN) is a minimally invasive procedure which utilizes imaging guidance (US, uoros­copy, CT) to place a needle and subsequent catheter into the urinary collecting system allowing for urinary drainage and easy access for additional procedures. The rst description of PCN was in 1955 by Drs. Goodwin, Casey, and Wolfe using exclusively uoroscopy and radiographic landmarks for guidance as a “natural outgrowth” from antegrade pyelography with an original success rate of 69%. These pio­neers described difculties accessing a minimally dilated collecting system, verifying proper positioning within the renal pelvis, and having a sufciently long needle [27]. These issues are still worth consideration today when plan­ning the procedural approach.
Indications for PCN recognized by the Society of Interventional Radiology (SIR) include urinary drainage in the presence of obstruction, urinary diversion to facilitate healing of stula/urinary leak/hemorrhagic cystitis, access for subsequent procedures (primarily PCNL), or need for collecting system access when retrograde access can’t be achieved [28].
Improvements in the technique have led to success­ful PCN rates ranging from 96% to 99% in multiple studies with the SIR expected success rate of 96% in a
481
Key Point
Indications for PCN:
• Urinary drainage for obstruction
• Urinary diversion to facilitate healing
• Access for subsequent procedures
• When retrograde access can’t be achieved
simple native kidney with a dilated collecting system. The lowest success rates of 85% are observed when attempting PCN on non- dilated kidneys with large stag-
horn calculi [28, 29]. While this procedure can be per­formed on an outpatient basis, the patient’s clinical situation may preclude this and require inpatient moni­toring overnight.
Pre-procedural evaluation should include reviewing the available imaging for kidney orientation, presence, and size of stones, examination of the collecting system for evidence of duplication, and presence of renal cysts or masses. The presence of any of these abnormalities may make the procedure technically more difcult and increase the chances of complications. A review of the lab data is critical as the presence of an uncorrectable severe coagulopathy is a rela­tive or potentially absolute contraindication to the procedure. PCN is a Category 3 procedure (signicant risk of bleeding/ bleeding difcult to detect) under the SIR guidelines; there­fore, the following is recommended: platelets >50,000/mm
3
INR1.5, and aPTT 1.5× control values. A review of the patient’s medications for any anticoagulants is also impor­tant. As a Category 3 procedure, many anticoagulants should also be held prior to the procedure based on SIR guidelines (Table43.5). Furthermore, it is prudent to have a discussion with the patient and/or patient’s family regarding aftercare of their nephrostomy tube including dressing changes, record­ing outputs, ushing if needed, and required follow-up care.
,
Table 43.5 SIR recommended medication hold times prior to percutaneous nephrostomy
Warfarin (Coumadin) Heparin Therapeutic LWMH (Lovenox) 24h/2 doses Fondaparinux Clopidogrel (Plavix)
Prasugrel (Efent) Ticlopidine (Ticlid) 7days Short-acting NSAIDS (ibuprofen, etc.) 24h Intermediate-acting NSAIDS (naproxen, etc.) 2–3days Long-acting NSAIDS (meloxicam, etc.) 10days Glycoprotein 2b/3a short acting (integralin/aggrastat) 4h Glycoprotein 2b/3a long acting (ReoPro) Argatroban (Acova) Defer until off treatment, emergent hold for 4h Bivalirudin (Angiomax) Dabigatran (Pradaxa)
5days, INR1.5 2–4h, aPTT 1.5×
2–3days (CrCl >50), 3–5days (CrCl 50) 5days
24h, aPTT 1.5×, ACT <150
Defer until off treatment, emergent hold 2–3h (CrCl >50), 3–5h (CrCl 50) Defer until off treatment, emergent hold 2–3days (CrCl >50), 3–5days (CrCl 50)
482
segmental arteries
L. A. Byers and P. J. Rochon
Apical
Anterior superior segmental artery
Anterior inferior
segmental artery
Inferior segmental
artery
Posterior
Anterior division
Posterior division
Fig. 43.2 Lateral oblique view of the kidney viewed into the renal
hilum. The renal artery divides into anterior (ventral) and posterior (dorsal) divisions, with the anterior division supplying the anterior two­thirds of the kidney and the posterior division supplying the posterior one-third of the kidney. The anterior division further divides into seg­mental arteries (apical, anterior superior, anterior inferior, and inferior segmental arteries). The posterior division becomes the posterior
The How To
1. The patient may be positioned in either the prone or lateral decubitus position. Often prior to sterile preparation and draping the patient, a scout image will be taken with marking of the anticipated entry point. Attempting to access just posterior to the mid-coronal plane of the kidney can potentially reduce bleeding due to relatively decreased vascu­larity; this plane is called the avascular plane of
43.2).
2. If The nephrostomy tube is being placed for subse­quent PCNL access, the targeted calyx should allow
segmental artery. Along the lateral and posterior aspects of the kidney, the two renal artery divisions form an arcade of small vessels that have sagittal plane of relatively decreased vessel density known as the avas­cular plane of Brodel or Brodel’s line. In addition, there are fewer ves­sels along the inferior aspect of this plane, and as such the inferior renal calyx is often used as a target when placing a percutaneous nephros­tomy tube, as illustrated by the needle
for the optimal surgical approach, and planning may need to be discussed with the patient’s urolo­gist. This may necessitate upper pole access, which is technically more challenging and may require an intercostal approach.
3. and deep anesthesia, a long coaxial needle is used to enter the collecting system under US or CT
43.3, 43.4, 43.5, and 43.6).
4. The inner stylet of the needle is removed and urine
location within the collecting system and subse-
43 Obstructive Uropathy
483
Fig. 43.3 (a) A 56-year-old male with multiple bilateral renal calculi.
Maximum intensity projection (MIP) demonstrating severe bilateral hydronephrosis. Note that on the left, there is contrast lling the dilated calyces and renal pelvis (thick arrow). There is also mild parenchymal thinning (thin arrow). (b) There is severe hydronephrosis on the left (thick arrow) with marked renal pelvis dilation, blunted calyces, and parenchymal thinning. The hydronephrosis is due to an obstructive distal left ureteral stone (thin arrow). (c) Longitudinal ultrasound of the same patient, which again demonstrates severe hydronephrosis. (d) Doppler ultrasound demonstrating signal within the renal hilum, which exhibits
“twinkle” and “comet tail” artifacts indicative of renal calculi. (e) Intra­procedural grayscale ultrasound of the kidney demonstrates needle (thick arrows) access of the renal calyx (thin arrow). The needle will appear as a linear hyperechoic structure. (f) Fluoroscopic image of the same patient demonstrating placement of percutaneous nephrostomy catheter within the left renal pelvis with iodinated contrast partially out­lining the collecting system. There are multiple lling defects in the renal calyces and renal pelvis (big arrow) that represent calculi. In addi­tion, there is contrast pooling at a lling defect in the distal left ureter (small arrow) corresponding to the obstructing calculi seen on CT
484
L. A. Byers and P. J. Rochon
20°-30°
Fig. 43.4 Sagittal view of the patient depicting positioning and
targeting for an inferior calyx approach ultrasound-guided nephros­tomy tube. The probe should be held parallel to the long axis (sagittal
quently aspirated. Decompression followed by
setting of infection as the increase in renal pelvic pressure can result in urosepsis.
5. A wire is advanced through the needle into the
is removed. (a) If access of the lower urinary tract is desired,
a catheter may be used to guide the wire into the ureters and subsequently the bladder.
(b) For nephroureterostomy tubes, the wire should
be advanced into the bladder which may require the use of different catheters if crossing an obstruction.
6. A nephrostomy or nephroureterostomy tube is advanced over the wire. Once in position, the wire can be removed.
7. The string of the catheter should be pulled back
axis) of the kidney with the needle angled at approximately 20–30° perpendicular relative to the patient’s skin
8. If a nephroureterostomy tube is used, there should be a pigtail coil in the bladder and in the renal pelvis.
9. The catheter is then attached to a bag for drainage.
devices. It is important to ensure that urine still
are in place.
10. Urinary drainage should be monitored closely after
tinged, however should clear over this period. If drainage remains bloody, evaluation of renovascular
­eurysm may be performed with Doppler ultrasound, contrast-enhanced CT, CT angiography, or conven­tional angiography. Note that conventional angiog­raphy remains the gold standard for evaluation of a
contrast.
allow for endovascular treatment. Hemodynamics and lab data should also be correlated.
43 Obstructive Uropathy
Fig. 43.5 (a) Percutaneous
needle access of the right kidney with wire coiling within the renal pelvis. This is further conrmed with return of urine. (b) The percutaneous nephrostomy tube can then be advanced over the wire and contrast injected into the renal pelvis (antegrade nephrostogram) to further evaluate collecting system anatomy and evaluate for distal obstruction
485
Fig. 43.6 Common devices used for percutaneous nephrostomy tube
placement. Top to bottom: 21G Chiba needle with inner stylet, coaxial sheath with dilator, guidewire, and pigtail nephrostomy catheter with metallic stiffener
Key Point
The safest place to access the kidney is in the avascular plane of Brodel, just posterior to the lateral border of the kidney, and has a relative paucity of vessels.
Key Point
Remember, posteriorly the lung ends at the 10th rib and the pleura ends at the 12th rib.
Key Point
A nephrostomy tube has a “pigtail” end. It can be straightened with a plastic or metal inner stiffener, depending on user preference. Once the tip of the cath­eter is into the collecting system, hold the stiffener still and advance the remainder of the catheter over the wire into the renal pelvis to form the pigtail. Pulling on the string will tighten the pigtail.
After the procedure, signs and symptoms to monitor include worsening pain at a location other than the skin inci­sion, increasing blood in the draining urine, precipitous decrease in nephrostomy tube output, declining hematocrit, and new/worsening fevers or leukocytosis. Any of these should prompt further evaluation as they are concerning for major complications (Table43.6) [28, 30, 31].
Dressing change schedules should be tailored to ensure the dressings remain clean and dry to prevent skin maceration and infection. During immediate postprocedural period, the patient or a caretaker may need to irrigate the nephrostomy tube until the draining urine is clear to prevent clot and obstruction within the catheter. When possible, this should be done using clean (or even sterile) technique and sterile saline ush syringes. Prior to disconnecting the drainage bag, ensure that the tubing is clamped to prevent urine spillage. Clean the hub with either chlorhexidine or alcohol and then attach the saline ush. Irrigate the tubing with 5–10cc of saline accounting for the length of the tubing. Clean the nephrostomy tube hub
486
L. A. Byers and P. J. Rochon
Table 43.6 Complications of percutaneous nephrostomy
Major
Septic shock 1–10% Hemorrhage requiring transfusion 1–4% Vascular injury requiring intervention 0.1–1% Bowel transgression 0.2–0.5% Pleural complications 0.1–0.6%, 8.7–12% when
Transfer to ICU, emergent surgery, delayed discharge
Minor
Catheter dislodge/malposition 4.8% Pelvic perforation 4.3% Paralytic ileus 2.4% Fever >6h 13.6
upper pole access required 1–7%
and drainage bag connector and reconnect the tubing. Ensure that urine is once again freely owing into the drainage bag. Nephrostomy tubes will need to be exchanged periodically due to urine crystalline precipitation and subsequent obstruc­tion. Classically, this was approximately every 3months; how­ever, new research suggests that there is higher patient compliance, reduced rate of infection, and reduced cost asso­ciated with a 2-month exchange schedule [32].
External nephrostomy tubes may ultimately be removed once the obstruction has resolved or an internal drainage pathway has been established such as with an internal dou­ble- J nephroureteral stent. This may be further demonstrated with repeated antegrade nephrostogram to ensure urine ows freely to the bladder. Despite slightly different construction between manufactures, the steps to removing a nephrostomy tube are essentially the same.
1. Remove all dressings and clean the skin. Ensure the
nephrostomy tube is clamped and the drainage bag is
disconnected.
2. Cut any anchoring sutures and remove any afxing devices.
Afxing devices usually have solvents to loosen the glue.
3. Grasp or use a hemostat to lightly clamp onto the tubing
near the skin and cut the catheter tubing at the hub. This
releases the string running the length of the catheter which
forms the pigtail. Have gauze ready with the other hand as
some urine will likely leak out when the tube is removed.
4. Remove the catheter. There may be some slight resis-
tance as the pigtail fully straightens; a wire can be used
to assist with this. If signicant resistance is met, stop
and reassess.
(a) For a routine exchange of the nephrostomy tube, the
catheter should be removed over a wire with plenty of purchase of wire within the collecting system. A new catheter is placed over the wire under uoro guidance similar to original placement.
5. Clean the area again and apply a dry dressing.

References

1. Anderson JC, Chapter I.The nurserymen—a historical survey. In: Hydronephrosis. Oxford: Butterworth-Heinemann; 1963. p.1–9.
2. Staples GA. Hydronephrosis: an essay based upon the com­parative study of seventy-one cases of that lesion, of which one case came under the personal observation of the writer. JAMA. 1884;II(15):393–402.
3. Opdenakker L, Oyen R, Vervloessem I, Goethuys H, Baert AL, Baert LV, etal. Acute obstruction of the renal collecting system: the intrarenal resistive index is a useful yet time-dependent parameter for diagnosis. Eur Radiol. 1998;8(8):1429–32.
4. Bascands J-L, Schanstra JP.Obstructive nephropathy: insights from genetically engineered animals. Kidney Int. 2005;68(3):925–37.
5. Chevalier RL.Pathogenesis of renal injury in obstructive uropathy. Curr Opin Pediatr. 2006;18(2):153–60.
6. Khalaf IM, Shokeir AA, El-Gyoushi FI, Amr HS, Amin MM. Recoverability of renal function after treatment of adult patients with unilateral obstructive uropathy and normal contralat­eral kidney: a prospective study. Urology. 2004;64(4):664–8.
7. Watson WJ, Brost BC. Maternal Hydronephrosis in pregnancy: poor association with symptoms of ank pain. Am J Perinatol. 2006;23(08):463–6.
8. Cheung KL, Lafayette RA.Renal physiology of pregnancy. Adv Chronic Kidney Dis. 2013;20(3):209–14.
9. Scales CD Jr, Smith AC, Hanley JM, Saigal CS.Prevalence of kid­ney stones in the United States. Eur Urol. 2012;62(1):160–5.
10. de Seze M, Rufon A, Denys P, Joseph PA, Perrouin-Verbe B. The neurogenic bladder in multiple sclerosis: review of the literature and proposal of management guidelines. Mult Scler. 2007;13(7):915–28.
11. Tandogdu Z, Wagenlehner FM. Global epidemiology of urinary tract infections. Curr Opin Infect Dis. 2016;29(1):73–9.
12. Hooton TM, Scholes D, Stapleton AE, Roberts PL, Winter C, Gupta K, et al. A prospective study of asymptomatic bac­teriuria in sexually active young women. N Engl J Med. 2000;343(14):992–7.
13. Grases F, Costa-Bauzá A.Simplied methods for the evaluation of the risk of forming renal stones and the follow-up of stone-forming propensity during the preventive treatment of stone-formation. Urolithiasis. 2016;44(1):77–82.
14. Fernbach SK, Maizels M, Conway JJ.Ultrasound grading of hydro­nephrosis: introduction to the system used by the Society for Fetal Urology. Pediatr Radiol. 1993;23(6):478–80.
15. Nguyen HT, Benson CB, Bromley B, Campbell JB, Chow J, Coleman B, etal. Multidisciplinary consensus on the classication of prenatal and postnatal urinary tract dilation (UTD classication system). JPediatr Urol. 2014;10(6):982–98.
16. Rickard M, Easterbrook B, Kim S, Farrokhyar F, Stein N, Arora S, etal. Six of one, half a dozen of the other: a measure of multi­disciplinary inter/intra-rater reliability of the society for fetal urol­ogy and urinary tract dilation grading systems for hydronephrosis. JPediatr Urol. 2016;13:80.e1–5.
17. Smith RC, Verga M, McCarthy S, Roseneld AT.Diagnosis of acute ank pain: value of unenhanced helical CT.AJR Am JRoentgenol. 1996;166(1):97–101.
18. Schwartz BF, Schenkman N, Armenakas NA, Stoller ML.Imaging characteristics of indinavir calculi. JUrol. 1999;161(4):1085–7.
19. Liu CC, Li CC, Shih MC, Chou YH, Huang CH. Matrix stone. JComput Assist Tomogr. 2003;27(5):810–3.
20. Assimos D, Krambeck A, Miller NL, Monga M, Murad MH, Nelson CP, et al. Surgical Management of Stones: American uro­logical association/Endourological society guideline, part I.J Urol. 2016;196(4):1153–60.
43 Obstructive Uropathy
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21. Miller OF, Kane CJ. Time to stone passage for observed ureteral calculi: a guide for patient education. JUrol. 1999;162(3 Pt 1):688–
90. discussion 90-1
22. Albala DM, Assimos DG, Clayman RV, Denstedt JD, Grasso M, Gutierrez-Aceves J, etal. Lower pole I: a prospective randomized trial of extracorporeal shock wave lithotripsy and percutaneous nephrostolithotomy for lower pole nephrolithiasis-initial results. JUrol. 2001;166(6):2072–80.
23. De S, Autorino R, Kim FJ, Zargar H, Laydner H, Balsamo R, et al. Percutaneous nephrolithotomy versus retrograde intrarenal surgery: a systematic review and meta-analysis. Eur Urol. 2015;67(1):125–37.
24. Somani BK, Nabi G, Thorpe P, Hussey J, Cook J, N'Dow J.Is percutaneous drainage the new gold standard in the management of emphysematous pyelonephritis? Evidence from a systematic review. JUrol. 2008;179(5):1844–9.
25. McVary KT, Roehrborn CG, Avins AL, Barry MJ, Bruskewitz RC, Donnell RF, etal. Update on AUA guideline on the management of benign prostatic hyperplasia. JUrol. 2011;185(5):1793–803.
26. Rouprêt M, Babjuk M, Compérat E, Zigeuner R, Sylvester RJ, Burger M, etal. European Association of Urology guidelines on
upper urinary tract urothelial cell carcinoma: 2015 update. Eur Urol. 2015;68(5):868–79.
27. Goodwin WE, Casey WC, Woolf W.Percutaneous trocar (needle) nephrostomy in hydronephrosis. JAMA. 1955;157(11):891–4.
28. Pabon-Ramos WM, Dariushnia SR, Walker TG, d'Othee BJ, Ganguli S, Midia M, etal. Quality improvement guidelines for per­cutaneous nephrostomy. JVasc Interv Radiol. 2016;27(3):410–4.
29. Farrell TA, Hicks MEA. Review of radiologically guided per­cutaneous nephrostomies in 303 patients. J Vasc Interv Radiol. 1997;8(5):769–74.
30. Lee WJ, Patel U, Patel S, Pillari GP. Emergency percutaneous nephrostomy: results and complications. J Vasc Interv Radiol. 1994;5(1):135–9.
31. Saad WEA, Moorthy M, Ginat D. Percutaneous nephrostomy: native and transplanted kidneys. Tech Vasc Interv Radiol. 2009; 12(3):172–92.
32. McDevitt JL, Acosta-Torres S, Zhang N, Hu T, Odu A, Wang J, etal. Long-term percutaneous nephrostomy management of malig­nant urinary obstruction: estimation of optimal exchange frequency and estimation of the nancial impact of patient compliance. JVasc Interv Radiol. 2017;28(7):1036–42.e8.
Enteric Access andFeeding Tubes
JiHoonShin

Pathophysiology

Enteral and parenteral feeding is commonly used in both the inpatient and outpatient setting to provide nutritional support and meet the metabolic requirements for patients with inad­equate oral intake. Patients can tolerate up to 10days of par­tial fasting with IV hydration before severe protein catabolism occurs. Feeding tubes are used for patients in whom oral intake is either impossible or unsafe and for those unable to maintain caloric intake orally. Furthermore, a feeding tube can be used to decompress the bowel for those with small bowel or gastric outlet obstruction.
44
ated by the patient for extended durations. For long-term enteral nutrition, direct gastrostomy or gastrojejunostomy tubes are the most reliable and best method available. Compared with NG tube, gastrostomy demonstrated a higher percentage of prescribed feeding and greater improvement in nutritional state [1]. Gastrostomy tubes can be inserted surgi­cally, endoscopically, or radiologically to suite a patients need for enteric access.

Clinical Indications

Percutaneous Radiologic Gastrostomy (PRG)Tube
Key Point
Enteral=feeding through the GI tract Parenteral=delivering nutrition into a vein
The nasogastric (NG) tube and nasojejunal (NJ) tube are rst line for patients requiring enteric access. For placement, the tube is lubricated on the end, typically with viscous lido­caine, and inserted through a nostril. It is important for the patients’ head to be tipped down during placement to close the airway so that the tube does not inadvertently pass into the trachea. Placement location is conrmed with a radiograph. For NJ tubes, placement is ideally past the ligament of Treitz.
Direct enteral feeding by the NG or NJ route is simple; however these tubes are prone to clog and require frequent replacement. They are also uncomfortable and poorly toler-
J. H. Shin (*) University of Ulsan College of Medicine, Asan Medical Center, Department of Radiology, Seoul, Republic of Korea e-mail: jhshin@amc.seoul.kr
Broadly, there are two main indications for feeding tube placement, (1) enteric feeding and (2) gut decompression. Most commonly, long-term nutritional support is needed for patients with dysphagia. This may be secondary to numerous etiologies including esophageal obstruction, head and neck cancer, lesions extending into the mediastinum, and neuro­logic disorders. Radiologic placement is particularly useful for patients with upper GI cancer because its placement avoids the oral route which could disseminate tumor cells into the stoma. Gastric decompression may be needed for patients with gastric outlet obstruction, proximal small bowel obstructions, or gastroparesis.
Key Point
Indications for gastrostomy tube:
• Enteric feeding
• Gastric decompression
In the pediatric population, gastrostomy tubes are fre-
quently placed in patients with hydrocephalus, severe
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