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Файл:Ординатура / Хирургия / Библиотека им академика М.И. Перельмана / Книга_5444_Библиотеки_им_академика_М_И_Перельмана
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Index
378
reproductive system 25, 31
respiratory disorders
25
resveratrol (RE)
11
anticancer effect
88, 137, 162, 191, 192, 196,
198
antidiabetic effect
88, 117
as a bioactive agent
162
biological activities
85
and cardiovascular health
87
food sources
85, 291–292
glioblastoma multiforme, management of
93
nanoformulations
92–93, 326
neuroprotective effect
89, 120, 233, 237
pharmacological activities 158
pro-oxidant effect 161
structure 108, 137, 158
toxicity
295–296
retinoblastoma tumor suppressor (RB)
pathway
195
rheumatoid arthritis (RA) 25
rhubarb 114, 294
rifampicin
262
risk assessment, nanomaterials 149
ROS see reactive oxygen species
rosemary
138, 181
rutin
anticancer effect 191
anti-inflammatory effect 161
antimicrobial effect 279
pharmacological activities
158
structure 158
s
safety issues
dietary supplements 94
food nanopackaging 74
fortified foods 94
nanoparticles 75
nanotoxicity 74, 148–150, 168
safe consumption of polyphenols 61, 94
toxicity of polyphenols 302–303
saffron 181
SAH see subarachnoid hemorrhage
Salvia africana lutea extract
52
SARS-CoV-2 60
see also COVID-19
schizophrenia, polyphenol role in treatment
of 234
scopoletin
108
secondary messengers, antioxidant potential of
polyphenols at cell sites
29
secondary metabolites
21, 105, 106
second messengers, oxidative stress, inhibition
of
33–36
SEDDS see self-emulsifying drug delivery
systems
seeds
48
selenium nanoparticles
254
self-emulsifying drug delivery systems
(SEDDS)
206–207, 300
sensory evaluation, food products 179
SET see single electron transfer
shelf life of food products
meat products 146, 147
nanosensors
73
Shigella species, antimicrobial resistance 262
Shreya Life Sciences 239
signaling pathways 15, 249
angiogenesis
194
apoptosis 193, 194
Hippo/YAP signaling pathway 194
hypoxia-induced factor signaling
pathways
194
metastatic cancer 197–199
polyphenol interactions 27–30, 33–36
at cell sites 29
silver nanoparticles
149, 236, 329
silymarin 162
sinapic acid 107, 113
sinensetin 109
single electron transfer (SET) 116, 119
small intestine 348
smart food packaging 70, 71
solid lipid nanoparticles (SLNs) 163, 168,
205–206, 237, 251, 253, 254, 300, 319–321
solvent evaporation, nanoparticle synthesis 90
sophoraflavanone G 279
Soxhlet solvent extraction, isolation of
polyphenols from plants 122
soy beans 114, 163
soy flour 114
soy milk 115, 350
sperm, oxidative stress 25
spice polyphenols 47, 176–177, 180–184
antioxidant properties 177, 181
applications 177
https://t.me/medicina_free
Index 379
common spices and their
polyphenols
180–181
health benefits
177
nanodelivery systems
182–183
pharmaceutical applications
182
spice extracts
181, 182–184
spinacetin
37
SPR see surface plasmon resonance-based
detection
spray drying method
encapsulation 122, 124, 353
nanoparticle synthesis
90–91
Staphylococcus aureus
antimicrobial resistance 261, 262
polyphenolic antibacterial activity 54
steganacin 112
stilbenes
4–5, 83, 268, 315, 346
antidiabetic effect 117
food sources 156
structure 108, 231–232
stomach (gastric) cancer 190, 191, 202
strawberries
293
Streptococci mutans, polyphenol effectiveness
against
84
stress, polyphenol role in treatment of 234
stroke
228, 233
subarachnoid hemorrhage (SAH) 228
sulfanilamides 266–267
sulforaphane 232
sulfuretin
276
supplements see dietary supplements
surface plasmon resonance (SPR)-based
detection 73
t
T2D see type-2 diabetes
TAMs see tumor-associated macrophages
tangeretin
anticancer effect 191
structure 109
tannic acid 11
tannins 315–316
condensed tannins (proanthocyanidins) 3,
10, 110–111, 270, 346
food sources 36, 293
signalling pathways and second
messenger 36
structure 36
hydrolysable tannins
10, 316
food sources
36, 292–293
signalling pathways and second
messenger
36
structure
36
taxifolin
273
TCA see tricarboxylic acid cycle
tea
black tea 48, 51, 315
anti-caries effect
84
cardiovascular benefits
60
phenolic content
114, 115
silver nanoparticles, stabilization of 329
green tea/green tea extract
12, 32, 48, 51, 53,
150
antibacterial effect
84
anticancer effect 56, 87, 88
antidiabetic effect 118
anti-inflammatory effect
138
antiobesity effect 163
depression, treatment of 234
neuroprotective effect 89, 233
phenolic content
114, 115
toxicity 297
negative effects on health 149
techtochrysin 278
tempeh
115
theaflavins (TF) 329
thearubigins (TR) 329
theophylline 159
therapeutic uses/potential see disease
management/prevention
thermal processing of food, and phenolic
content 50–51
thrombectomy 228
thyme 181, 182
thymol 144
thymol–zein nanoparticles 144
thyroid, resveratrol toxicity 296
tiliroside 32–37, 284
TMC see transition metals chelation
TME see tumor microenvironment
tofu 114
tomatoes 114
topoisomerases, inhibition of 280
toxicity 293–304
animal studies 295, 296, 297, 302
dose-dependent effects 303
https://t.me/medicina_free
Index
380
future research 303–304
lead-induced toxicity
12
medication interactions
303
nanotoxicity
148–149, 157, 168
of polyphenols
149–150, 294–298
safety considerations
302–303
sensitivity of individuals to polyphenols
303
strategies to combat
298–302
toxic plants/foods
293–294
TP53 gene, apoptosis
194
TR see thearubigins
traditional medicine, treatment of
depression 234
transcription factors, polyphenol impact on 14
transition metals chelation (TMC) 116, 119
transportation, food product condition
during
73–74
tricarboxylic acid (TCA) cycle 266
tuberculosis 262, 263
tumor-associated macrophages (TAMs) 199,
200
tumor cells, regulation of cell cycle
195
tumor microenvironment (TME) 199, 200, 201
turmeric 60, 181, 292
type-2 diabetes (T2D) 46, 53, 115–116
tyrospol
89
u
umbelliferone 107
uridine diphosphate glucuronosyltransferases
(UGT)
348
urinary tract infections
262
urine
metabolites discharged in 349
polyphenols in 349
USA
antibiotic-resistant infections 262
polyphenol business
37
UV damage, protection from 7, 138
v
vanillic acid 106
vanillin
115
vascular endothelial growth factor (VEGF)
angiogenesis 194
metastatic cancer
198
vegetables
48, 49
food processing effect on
51
nanopackaging technology
147
phenolic content
113–115
see also specific vegetables
VEGF see vascular endothelial growth factor
vescalin
111
vitamins
156
vitexin 273
Vitis rotundifloia 53
w
walnuts 53
Warburg effect 266
water-in-oil (W/O) nanoemulsions 178
wet milling, nanoparticle synthesis
91
whey protein nanoparticles 141, 302
wine production, microbe detection 73
wine, red 315, 346
cardioprotective effect 11
concentration of polyphenol in plasma
350
neuroprotective effect 57, 88–89, 232
phenolic content 114, 115
Wnt signaling pathway, metastatic cancer 199
W/O see water-in-oil nanoemulsions
wogonin
191
wound infections 262
x
xanthohumol 192
y
yeast encapsulation 123, 125
yew 294
z
zein films 147–148
zein–rhamnoid composite nanoparticles 168
https://t.me/medicina_free
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