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NEWBORN METRIC CONVERSION TABLES
Temperature
FAHRENHEIT (F) TO CELSIUS (°C)
°F °C °F °C °F °C °F °C
95.0 35.0 98.0 36.7 101.0 38.3 104.0 40.0
95.2 35.1 98.2 36.8 101.2 38.4 104.2 40.1
95.4 35.2 98.4 36.9 101.4 38.6 104.4 40.2
95.6 35.3 98.6 37.0 101.6 38.7 104.6 40.3
95.8 35.4 98.8 37.1 101.8 38.8 104.8 40.4
96.0 35.6 99.0 37.2 102.0 38.9 105.0 40.6
96.2 35.7 99.2 37.3 102.2 39.0 105.2 40.7
96.4 35.8 99.4 37.4 102.4 39.1 105.4 40.8
96.6 35.9 99.6 37.6 102.6 39.2 105.6 40.9
96.8 36.0 99.8 37.7 102.8 39.3 105.8 41.0
97.0 36.1 100.0 37.8 103.0 39.4 106.0 41.1
97.2 36.2 100.2 37.9 103.2 39.6 106.2 41.2
97.4 36.3 100.4 38.0 103.4 39.7 106.4 41.3
97.6 36.4 100.6 38.1 103.6 39.8 106.6 41.4
97.8 36.6 100.8 38.2 103.8 39.9 106.8 41.6
NOTE: °C = (°F – 32) × 5⁄9. Celsius temperature equivalents have been rounded to one decimal place by adding 0.1 when the second decimal place is 5 or greater.
See inside back cover for additional tables.

Merenstein & Gardner’s Handbook of
NEONATAL INTENSIVE CARE:
AN INTERPROFESSIONAL
APPROACH

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Merenstein & Gardner’s Handbook of
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NEONATAL INTENSIVE CARE:
AN INTERPROFESSIONAL
APPROACH
MARY ENZMAN-HINES, Ph D, APRN, CNS, CPNP, APHN-BC
9th
edition
SANDRA L. GARDNER, RN, MS
Retired Clinical Nurse Specialist;
Retired Pediatric Nurse Practitioner;
Director, Professional Outreach Consultation;
Aurora, Colorado
BRIAN S. CARTER, MD, FAAP
Professor of Pediatrics
University of Missouri-Kansas City School of Medicine
Division of Neonatology & Bioethics Center
Children’s Mercy Hospital-Kansas City
Kansas City, Missouri
Professor Emeritus
Beth El College of Nursing and Health Sciences
University of Colorado at Colorado Springs;
Certified Pediatric Nurse Practitioner
Co-Owner of Integrative Pediatric Health Care
Englewood, Colorado
SUSAN NIERMEYER, MD, MPH, FAAP
Professor
Department of Pediatrics
University of Colorado Denver
Anschutz Medical Campus
School of Medicine
Aurora,
Colorado

Elsevier
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3251 Riverport Lane
St. Louis, Missouri 63043
MERENSTEIN & GARDNER’S HANDBOOK OF NEONATAL INTENSIVE
CARE NURSING: AN INTERPROFESSIONAL APPROACH, NINTH EDITION ISBN: 978-0-323-56903-3
Copyright © 2021 by Elsevier, Inc. All rights reserved.
No part of this publication may be reproduced or transmitted in any form or by any means, electronic or
mechanical, including photocopying, recording, or any information storage and retrieval system, without
permission in writing from the publisher. Details on how to seek permission, further information about the
Publisher’s permissions policies and our arrangements with organizations such as the Copyright Clearance
Center and the Copyright Licensing Agency, can be found at our website: www.elsevier.com/permissions.
This book and the individual contributions contained in it are protected under copyright by the Publisher
(other than as may be noted herein).
Notice
Practitioners and researchers must always rely on their own experience and knowledge in evaluating and
using any information, methods, compounds or experiments described herein. Because of rapid advances
in the medical sciences, in particular, independent verication of diagnoses and drug dosages should be
made. To the fullest extent of the law, no responsibility is assumed by Elsevier, authors, editors or contributors for any injury and/or damage to persons or property as a matter of products liability, negligence or
otherwise, or from any use or operation of any methods, products, instructions, or ideas contained in the
material herein.
Previous editions copyrighted Copyright © 2016, 2011, 2006, 2002, 1998, 1993, 1989, 1985 by Mosby, Inc.,
an aliate of Elsevier Inc.
Library of Congress Control Number: 2019955906
Content Strategist: Lee Henderson
Content Development Specialist: Laura Klein
Publishing Services Manager: Deepthi Unni
Project Manager: Srividhya Vidhyashankar
Design Direction: Bridget Hoette
Printed in the United States of America
Last digit is the print number: 9 8 7 6 5 4 3 2 1

We dedicate this edition to the memory of Gerald B. Merenstein, MD—our friend,
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colleague, and mentor who was also a wonderful husband, father, and grandfather. As the
inspiration for this text, Gerry contributed to the fields of neonatal and pediatric care
through his dedication to nurses, nurse practitioners, child health associates, interns, residents,
fellows, neonates, and their families. We miss him every day and know that his empathy,
knowledge, teaching, and compassion influences all of us, as well as the newborns, children,
and families that he and we serve.
SLG BSC MEH SN
In memory of Stephanie Marie Gardner, whose three days of life did have a purpose.
To Muffy Roo, Millie Moo, and Mollie Mittens, my sweet rescue dogs, for their eminent
patience for the last 3 years!
SLG
To my family: Angel, Sean, Yvonne, Rebecca, and Jacquelyn; my mentors and colleagues; and
all of the children and families who have allowed me to share with them both joyous and
difficult times in their lives.
BSC
To my family: James, Jennifer, Sean, Finnoula, Steve, and Sarah for their enduring source of
love, confidence, and encouragement and to all the families who have informed my practice
and knowledge about caring for fragile infants.
MEH
To all of the babies, families, and dedicated caregivers who have been my constant teachers;
my mentor Jacinto Hernandez, who opened my horizons to a larger world; and my husband
John for his unfailing love and support.
SN
In Memoriam
Billy F. Andrews Sr., MD
Jimmie Lynne Scholl Avery
L. Joseph Butterfield, MD
Lula O. Lubchenco, MD
William A. Silverman, MD

CONTRIBUTORS
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Rita Agarwal, MD, FAAP
Clinical Professor of Anesthesiology
Department of Anesthesiology;
Associate Director
Pediatric Anesthesia Education
Department of Anesthesiology
Lucille Packard Children’s Hospital Stanford
Stanford, California
Anne M. Ambia, MD
Assistant Professor of Obstetrics and Gynecology
Division of Maternal-Fetal Medicine
University of Texas Southwestern
Dallas, Texas
James S. Barry, MD
Medical Director
Neonatal Intensive Care Unit;
Associate Professor of Pediatrics
Department of Pediatrics
Section of Neonatology
University of Colorado School of Medicine
Children’s Hospital Colorado
Aurora, Colorado
Terri J. Bisio, BSN
Registered Nurse
Kidney Center
Children’s Hospital
Aurora, Colorado
Wanda T. Bradshaw, MSN, RN, NNP-BC
Assistant Professor and Lead Faculty NNP Specialty
Duke University School of Nursing
Durham, North Carolina;
Neonatal Nurse Practitioner
Cone Health
Greensboro, North Carolina
M. Colleen Brand, PhD, APRN, NNP-BC
Neonatal Nurse Practitioner
Department of Neonatology
Texas Children’s Hospital;
Assistant Professor
Pediatrics-Newborn
Baylor College of Medicine
Houston, Texas
Bridget M. Bronsert, DNP, MSN, RNC, NNP-BC
Neonatal Nurse Practitioner
Clinical Coordinator
Neonatal Intensive Care Unit
SCL Lutheran Medical Center
Wheat Ridge, Colorado
Laura D. Brown, MD
Associate Professor
Department of Pediatrics
University of Colorado School of Medicine
Aurora, Colorado
Jessica L. Brunkhorst, MD
Assistant Professor of Pediatrics
Division of Neonatology
Children’s Mercy
Kansas City, Missouri
Deanne Buschbach, RN, MSN, NNP, PNP
Director
Center for Advanced Practice
Neonatology and Center for Advanced Practice
Duke University Medical Center
Durham, North Carolina
Melissa A. Cadnapaphornchai, MD
Pediatric Nephrologist
Rocky Mountain Pediatric Kidney Center
Rocky Mountain Hospital for Children/Presbyterian
St. Luke’s Medical Center
Denver, Colorado
vi

CONTRIBUTORS
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vii
Betsy H. Cammack, MD
Neonatal-Perinatal Medicine Fellow
Division of Neonatology
Children’s Mercy Hospital
Kansas City, Missouri
Suzanne M. Carrington, DNP, CNM
Assistant Professor
College of Nursing
University of Colorado
Aurora, Colorado
Angel Carter, DNP, APRN, NNP-BC
Advanced Practice Registered Nurse
Ambulatory Neonatology
Children’s Mercy Hospital
Kansas City, Missouri
Brian S. Carter, MD, FAAP
Professor of Pediatrics
Medical Humanities & Bioethics
Pediatrics—Neonatology
University of Missouri—Kansas City School of
Medicine;
Bioethicist
Bioethics Center
Children’s Mercy Hospital
Kansas City, Missouri
Heather Furlong Brown, MD
Associate Professor of Pediatrics
Division of Neonatology
University of Louisville School of Medicine
Louisville Kentucky
Jane Davis, BSN, RNC-NIC
Charge Nurse
Neonatal Intensive Care Unit
University of Colorado Hospital
Aurora, Colorado
Jane Deacon, NNP-BC, MS
Neonatal Nurse Practitioner
Children’s Hospital Colorado
Aurora, Colorado
David J. Durand, MD
Neonatologist
Division of Neonatology
UCSF Benioff Children’s Hospital—Oakland
Oakland, California
Nancy K. English, PhD, APRN, CHPN, CT
Professor
College of Nursing
University of Colorado
Denver, Colorado
Susan B. Clarke, MS, BSN, RNC-NIC, RN-BC, CNS
Retired, Professional Development Specialist
Professional Development Department
Children’s Hospital Colorado
Aurora, Colorado
Kristi Coe, MSN, NNP, CNS, PNP
Consulting Associate, MSN Program
Duke University School of Nursing
Durham, North Carolina;
Neonatal Nurse Practitioner
Neonatal Intensive Care Unit
Cone Health
Greensboro, North Carolina
Mary Enzman-Hines, PhD, APRN, CNS, CPNP, APHN-BC
Beth El College of Nursing and Health Sciences
Department of Nursing
University of Colorado at Colorado Springs;
Professor Emeritus
Department of Nursing
University of Colorado at Colorado Springs
Colorado Springs, Colorado;
Certified Pediatric Nurse Practitioner
Co-Owner, Integrative Pediatric Health Care, LLC
Englewood, Colorado
Lori Erickson, BSN, MSN
CHAMP Clinical Program Manager
Ward Family Heart Center
Children’s Mercy Hospital—Kansas City
Kansas City, Missouri

CONTRIBUTORSviii
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Ruth Evans, BSN, MSN, NNP-BC
Neonatal Nurse Practitioner
Children’s Hospital Colorado
Aurora, Colorado
Amanda Flaherty, BSN, RNC-NIC
Transport RN
Neonatal Intensive Care Unit
Valley Children’s Hospital
Madera, California
Patricia A. Froese, DNP, APRN, NNP-BC
Neonatal Nurse Practitioner
Division of Neonatology
Cincinnati Children’s Hospital
Cincinnati, Ohio
Margaret E. Gallagher, MD
Pediatric Surgeon
Department of Surgery
Brooke Army Medical Center
San Antonio, Texas
Sandra L. Gardner, RN, MS
Retired Clinical Nurse Specialist
Retired Pediatric Nurse Practitioner
Director
Professional Outreach Consultation
Aurora, Colorado
Edward Goldson, MD, FAAP
Professor
Department of Pediatrics
University of Colorado Medical
Children’s Hospital Colorado
Aurora, Colorado
William W. Hay Jr., MD, FAAP
Professor of Pediatrics
University of Colorado School of Medicine
Aurora, Colorado
Kendra Hendrickson, MS, RD, CNSC, CSP
Clinical Dietitian
Neonatal Intensive Care Unit
University of Colorado Hospital
Aurora, Colorado
Carmen Hernandez, MSN, NNP-BC
Neonatal Nurse Practitioner
Women’s Services
Lutheran Medical Center
Wheat Ridge, Colorado
Chi Hornik, PharmD, BCPS, CPP
Assistant Professor
Pediatrics and Pharmacy
Duke University Medical Center and Duke Clinical
Research Institute
Durham, North Carolina
Jodi Jackson, MD
Neonatologist
Department of Pediatrics
Children’s Mercy Hospital
Kansas City, Missouri;
Medical Director Neonatal Unit
Department of Pediatrics
AdventHealth, Shawnee Mission
Shawnee Mission, Kansas;
Chairperson, Director NAS Initiative
Kansas Perinatal Quality Collaborative
Topeka, Kansas
Ara S. Hall, MD
Assistant Professor
Neurology
University of Missouri—Kansas City
Kansas City, Missouri
Susan Harvey, BSN, MSN
Instructor—Nurse Practitioner
Center for Cancer and Blood Disorders
University of Colorado
Aurora, Colorado
M. Douglas Jones Jr., MD, FAAP
Professor
Department of Pediatrics
University of Colorado School of Medicine
Aurora, Colorado
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