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A. Pal et al.
the epidermal barrier. The most signicant biophysical factors determining this bar­rier’s current state are sebum excretion, trans-epidermal water loss, skin pH, and epidermal hydration. The application of preventative measures to restore the barrier function may benet from an understanding of the biophysical processes that occur in the skin [2]. The sebaceous and sweat gland secretions, including hydrating agents, amino acids, and lactic acids to keep the skin’s surface at a pH of ve to six, comprise the skin’s natural defence mechanism. The skin will feel tight and dry if acid is predominant; on the other hand, oily skin is caused by an overabundance of bases. Thus, restoring the natural equilibrium of acids and bases is a crucial part of cosmetic emulsions’ function in skin care, which helps achieve and maintain a youthful appearance [14] (Fig.5.4). Because skin is a living substance, it can react to mechanical contact by releasing biomarkers, creating sweat, or even getting a wound or blister. Furthermore, the characteristics and traits of an individual greatly inuence the properties of their skin. Because of this, skin contact behaviour is dif­cult to anticipate through modelling, necessitating ongoing experimental research [20].
5.3 Friction ofSkin
The rst person to thoroughly examine friction in connection to skin was Naylor (1955) [24]. He stated that “friction constitutes one of the frequent denigrates to which the human skin is exposed” in his 1955 paper [24]. Age, anatomical location, skin moisture, and skin health all affect skin friction. Tribology is a practical way to perform non-invasive methods to measure skin moisture and health quantitatively. A probe that is either spinning or sliding across the skin in a linear motion is used in quite a few of skin friction studies that are referenced in the literature. Materials for probes can be made of glass, nylon, polyethylene, stainless steel, or copper [14]. The primary factor inuencing friction behaviour is the amplitude of surface rough­ness; the smoother the surface, the more friction there is [15, 16].
A commercially accessible, portable Skin Micro-Tribometer type UMT, which is depicted in Fig.5.3, is equipped with multisensing technology. It offers thorough tribological measurements for many sample kinds in a range of biomedical applica­tions. To test bathroom tissues on skin, soap on skin, surgical staples and sutures, medical needles, shaving blades, aftershave creams, toothpaste and toothbrushes, for instance, it works well [12]. Typically, the forearm or ngertips were used for experiments [15, 16].
There are other factors inuencing skin friction behaviour including anatomical areas and measurement techniques [10]. The coefcient of friction is the tribologi­cal parameter that is often determined by putting a surface in touch with skin and moving the skin in relation to the surface [24].
F
N
5 Tribological Measurements ofHuman Skin
Fig. 5.3 Skin Micro­Tribometer model UMT
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The perpendicular force is known as the normal force N when two surfaces come into contact. The force that prevents relative motion between the two surfaces is known as the friction force, or F.The proportion of the friction force to the normal force is known as the coefcient of friction, or μ [24].
The static friction coefcient (μs) and the dynamic or kinetic friction coefcient (μk) are two different ways to characterise the friction coefcient [24].
With the two surfaces moving at a rather constant speed, the majority of skin research has concentrated on the dynamic friction coefcients [24].
According to a study, hydrated skin exhibits an enhanced friction response, whereas dry skin exhibits a decreased friction response. Amontons’ law of friction states that the dynamic friction coefcient (μk) is not impacted by the normal load that is applied or the apparent area of contact between the surfaces at the time of measurement [24].
The experimental methodology for determining skin friction centres on applying a known normal force to a probe and determining the skin’s frictional resistance to the probe’s movement [24].
The friction coefcient is greatly and signicantly inuenced by the magnitude of surface roughness. Take note of this to see the rise in friction at low surface roughness values clearly. For the horizontal axis, a logarithmic scale has to be used [15, 16]. There is a weak negative association between the friction coefcient and the skewness of the surface roughness. There is very little relationship between the friction coefcient and the kurtosis [15, 16]. The two types of experimental designs include (a) a linearly moving probe across the skin and (b) a rotating probe in
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contact with the skin surface [24]. There are substantial variations in friction coef­cients across different skin areas, attributing differences mainly to skin hydration and secondarily to surface or material properties [10]. The skin’s elastic modulus is a vital consideration in simulating and comprehending the contact and friction behaviour of human skin. Developing design guidelines for surfaces that come into contact with skin requires it. An accurate explanation of the biomechanical behav­iour of skin requires an anisotropic, nonlinear, viscoelastic model. The effective elastic modulus is the only parameter that adequately describes the skin’s mechani­cal behaviour in relatively modest deformations. Because of the intricate structure of the skin, effective elastic modulus dramatically falls as the length scale increases. Effective elastic modulus drops from 0.15 to 0.015MPa at an indentation depth of 10mm as the indenter radius of curvature increases (10mm to 10mm) [15, 16]. Forearm skin was used in invivo tribological tests to examine the impact of strati­ed stratum corneum on skin elasticity and frictional characteristics. The results showed that as more stratum corneum was eliminated, the skin’s elastic modulus fell and its friction coefcient increased. In order to demonstrate how water affects friction coefcient and the section change phenomenon of friction coefcient under varying degrees of tape strips, friction force vs normal force was presented.
As the amount of stratum corneum eliminated increased, the usual stiffness reduced but trans-epidermal water loss rose [4]. As depicted in Fig.5.3, understand­ing the mechanical behaviour of the skin under uniaxial and biaxial tension is essen­tial for various applications, including biomechanics, medical device design, and cosmetic product development. Uniaxial tension involves stretching the skin in a single direction, providing insights into its linear elasticity, ultimate tensile strength, and deformation characteristics. This information is crucial for understanding how the skin responds to forces encountered in everyday activities or during medical procedures. On the other hand, biaxial tension involves stretching the skin simulta­neously in two perpendicular directions, mimicking the more complex mechanical loading conditions the skin experiences in real-life scenarios. Studying biaxial ten­sion helps in comprehending the anisotropic nature of the skin, where its mechani­cal properties differ along different axes. This knowledge is instrumental in designing materials and products that accommodate the diverse and multidirectional forces exerted on the skin, contributing to advancements in areas such as tissue engineering, wound healing, and the development of comfortable and resilient wearable devices [18, 29] (Fig.5.4).
By utilising multi-sensor technology and real-time high-frequency data capture, the data quality of the tribological assessment of human skin invivo and in vitro may be signicantly enhanced [12]. The ndings of a study using FEM deformation simulation conrmed that one of the key inuencing variables inuencing the behaviour of the skin’s deformation in multi-asperity contact is the deformation interaction between asperities [31, 32]. Friction studies are a non-invasive method that provides a vital indicator of the health of the skin. A probe is positioned in rela­tion to the skin and brought into contact with it in order to measure friction. The friction coefcient is computed by monitoring a friction force that opposes the rela­tive movement between the skin and the probe [12].
5 Tribological Measurements ofHuman Skin
Fig. 5.4 Graphical representation of skin mechanical behaviour under (a) uniaxial and (b) biaxial tension [14, 29]
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The pin-on-disk tribometer (CSM Instruments) can be used to measure the coef­cient of friction (COF) between the skin and the steel or glass ball. Binder clips were used to secure the skins to a microscope slide. The tribometer’s rotary stage was superglued to this slide. The tribometer’s steel rod held the glass or steel ball in place. The supporting arm has a piezoelectric sensor inside of it. The frictional force that resulted from applying the normal load torqued the supporting arm. The sensor detected this torque, which then translated into COF and frictional force. The COF is measured in several scenarios [28] (Table5.1).
Additional research has demonstrated that the friction increases with the smooth­ness of the probe surface. Glass probe (hydrophilic) and polypropylene (hydropho­bic) across the skin of the forearm, and it was found that the glass probe produced less friction. This result was explained by the formation of a more stable water molecule lubricating coating on the glass [34]. Human ngers’ perception and con­tact with object surfaces lead to complex tribological behaviour. People apply their exploration style in this process under many situations, including contact load, slid­ing speed, sliding direction, and orientation angle between the ngers and the item surface, either consciously or unconsciously. With the exception of PFTE, which lowers friction by about 25% in comparison to the other materials, the probe mate­rial itself has no discernible effect [15, 16]. A piece of work demonstrated two forms of fang movement and addressed laboratory experimental instruments for fang active and passive tactile friction investigation. In an active sliding experiment, the subjects had to independently regulate the motion conditions as they slid their nger freely against the object’s surface [33].
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Table 5.1 Variation in friction coefcient in response to the variation in the probe [12]
Probe size, shape Material of the probe
15-mm ring Teon, Nylon,
Polyethylene, Wool
8-mm sphere Polyethylene Linear,
12-mm hemisphere
15-mm disc Teon Rotational Spring load 0.48 (Forearm)
Disc Glass Rotational Spring load 0.4 Lens Glass Linear,
3-mm sphere Ruby Linear Balloon; static
Stainless steel (rough, smooth)
Motion of the probe
Linear Static weights 0.2 (Teon)
Reciprocating Rotational Static weights 0.2–0.4 (Rough)
Reciprocating
Normal load setup
Static weights 0.5–0.6
Static weights 0.3–0.4 (Dry
weights
A. Pal et al.
Friction coefcient
0.4 (Nylon)
0.3 (Polyethylene)
0.4 (Wool)
0.3–0.6 (Smooth)
0.66 (Vulva)
skin)
0.7
5.4 Lubrication andSkin
It is evident that skin lubrication and friction play a signicant part in daily life; two examples are the feel of skin cream and the grip of sporting goods [1]. The moisture content of the skin’s surface determines how hydrated the skin is. The surface of the skin often becomes more frictional when wet. There have been reports that the fric­tion coefcients of skin can differ between wet and dry conditions by a factor of
1.5–7. Such a wide range most likely corresponds to the variety of materials, test strategies, and experimental settings that were employed. The amount of time that passes between measuring friction and applying moisturiser or exposing the skin to water is likely one of the most crucial variables [34]. A study demonstrates that a closed-form equation based on the skin’s anatomy exists for contact-based model­ling of human skin. This expression yields the skin’s effective elastic modulus’s magnitude as a function of the contact’s length scale, contingent upon variables like age, gender, and environmental conditions [27]. Young’s moduli for soft elastomers and the values obtained for hydrated stratum corneum are comparable. These mate­rials have been used extensively in lubrication and adhesion experiments because the relatively large compliance of the asperities produces an effective molecularly smooth contact [1]. Stribeck curve analysis depicted in Fig.5.5, in which the fric­tion coefcient is plotted against the sliding speed (speed/load) or lm thickness (lm thickness/roughness height), can be used to identify different lubrication regimes [14] entails plotting μ logarithmically against the group ηV/p [1]. Because silicone uids come in various viscosities and don’t noticeably plasticise the stra­tum corneum, they were chosen for this use. This illustrates how friction
5 Tribological Measurements ofHuman Skin
Fig. 5.5 Stribeck curve
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coefcients are similar to those for clean, dry skin and are relatively tiny for small values of the group ηV.The equation describes the boundary lubrication regime, which is what this is known as [1]. When low speeds and high loads are applied to surfaces, boundary lubrication takes place. These conditions result in a large contact area between the surfaces and little uid at the interface, which increases friction [23]. The mixed lubrication regime, in which hydrodynamic lubrication develops in specic portions of the point of contact rather than the entire contact area being entirely saturated as in the case of IEHL, is identied by the drop in coefcients in the shift between these two regimes [1]. Using AFM and nano indenters, tribologi­cal investigations were conducted to evaluate two synthetic skins and rat skin with and without cream. The application of cream caused by the existence of a cream lm resulted in an increase in COF, according to the data. As the tip moved across the skin-cream lm, the viscous friction between it and the lm increased the over­all frictional force [6]. Contact lenses and synovial joints are lubricated with bio­logical polymer solutions. Comprehending the degree to which these solutions produce hydrodynamic or boundary lms has signicant implications for manufac­turing goods that maximise consumer satisfaction. Optimising surface lubrication is a common goal in technical applications, with the goal of minimising wear and consuming less energy [14]. If the skin is sufciently wet, the bell-curve behaviour signals a transition from boundary to mixed lubrication [34]. The skin got fully hydrated in an extremely humid environment or in wet conditions, and sliding fric­tion has been reported to be 2–4 times higher than in dry settings [34]. The stick-slip behaviour of glass probes on clean, wet skin is most likely caused by the reduction in friction with increasing velocity in the mixed lubrication regime; this is because the maximum sliding velocities in the slip phases of the intermittent motion are signicantly faster than the imposed velocity [1].
The most signicant and notable factor affecting the friction of human skin is water or sweat, which can be found in the stratum corneum (skin hydration) or as liquid lms at the interface (aqueous lubrication) [11]. In order to assess the
160
lubricating qualities of the Gel- PBSG hydrogel patch on various skin types, appro­priate amounts of articial sebum were applied to replicate the characteristics of normal, oily, and dry skin. With the exception of dry skin simulation at 25°C with a constant force of 1.5N, the results showed identical friction values at the condi­tion evaluated for all materials, lower than that achieved with pig skin. The exis­tence of other skin constituents, such as hair, in addition to oil, explains the greater friction values seen for pig skin [13]. The skin gets moisturised in a humid environ­ment and friction increases twofold compared to a dry one. Because of the existence of facial stubble, the effect of skin hydration is presumably greater on the forearm than on the face [15, 16].
A. Pal et al.
5.5 Skin Sensation andPerception
Sensation is the ability of the skin to detect stimuli such as touch, pressure, tempera­ture, and pain; these receptors, including mechanoreceptors, thermoreceptors, and nociceptors, transmit signals to the brain, allowing us to perceive and respond to various stimuli; perception, on the other hand, is the brain’s interpretation of these signals, creating our subjective experiences of touch, warmth, or pain; the skin’s remarkable ability to sense and perceive stimuli is essential for tasks that range from ne motor skills to detecting potential threats. This intricate interplay of sensation and perception plays crucial roles in our daily experiences, providing a complex network of feedback that connects us to our environment. In an investigation, no discernible differences were found between the materials when several hard poly­mers and metals were tested. Aluminium and PTFE friction coefcients were exam­ined in the subsequent investigation. Two aluminium rings were employed, one with a surface roughness somewhat greater than the PTFE ring and one with a surface roughness slightly lower, to rule out any potential impacts of surface roughness. There was a slight but noticeable difference between aluminium and PTFE in this instance [15, 16].
5.6 Impact ofClothing andTextile
Since human skin and textiles contact so frequently, polymer fabrics have drawn attention from perception researchers. In addition to the fabric’s characteristics, it’s critical to comprehend the skin’s structure and characteristics in order to assess the function of the skin and how it interacts with various fabric materials. Finding the causes of skin friction can aid in the development of appropriate fabric composi­tions [6]. According to a study, the human hand and a three-axis dynamometer may be used to determine the coefcient of friction of fabric polymers with accuracy. The majority of the textiles had greater friction coefcients when oriented perpen­dicularly as opposed to parallelly. The poor correlation between the four tactile
5 Tribological Measurements ofHuman Skin
161
descriptors and the friction coefcient may be attributed to the involvement of mul­tiple additional fabric qualities in the tactile assessment process. Despite being very tiny, fuzziness had the strongest association with the friction coefcient [8]. The high friction at the fabric-skin interface can cause soreness, blisters, chang, and pressure ulcers, particularly in athletes who move quickly and for prolonged periods of time [6]. A study conducted an invivo analysis of understanding the stick-slip phenomena of biocompatible UHMWPE material in contact with human skin by using a modied tribometer, which proposed an analytical model which provides insights into the dynamics of dry and limited friction in the studied system [26]. The friction between skin and textile materials can be signicantly reduced by creating materials that are both low-friction and comfortable. It is possible to evaluate a wide range of skin-textile material friction conditions more easily by utilising simula­tions to build different patterns and textile models. The perception of textiles through touch is another eld that lacks much research. Even that getting ordinary injuries on the skin’s surface can result in overuse injuries elsewhere in the body, which could have long-term implications on a person’s general physical health, has been demonstrated. Enhancing our knowledge of the tribological interactions between human skin and clothing/fabrics is therefore crucial [6]. A study aimed to determine and enumerate how the frictional prole across the sock-skin interface was inu­enced by the knit structure (single jersey vs. terry), bre composition (polyester vs. cotton), bre linear density, and yarn type (lament vs. spun). The parametric design of experiments provided this information. In the dry condition, knit structure was determined to be the primary fabric characteristic inuencing the frictional force felt at the sock-skin contact for both trials (plastic probe and synthetic skin). Additionally, it was discovered that the kind of yarn and the linear density of the bre are tertiary factors inuencing the frictional force recorded at the sock-skin interface [9]. Skin interactions can both dene and hinder athlete performance; therefore, a better understanding of skin biomechanics is necessary to optimise the risk versus reward balance. Some sports aim to boost skin friction for improved effectiveness; however, this needs to be offset against injury risk given that skin abrades when slid across a rough and hard surface, delaminates when slid across a smooth and hard surface, and chafes or blisters when rubbed against certain fabrics repeatedly [19].
5.7 Skin Tribology inMedical Applications
People who have lost a portion of their body can live more normally thanks to pros­thetics. Research has been done on the interface between the human body and pros­thesis to ensure correct integration. Then, the residual limb-prosthesis contact was extensively modelled using the nite element approach. It was discovered that, as opposed to utilising a replica, the geometry of the socket should be adjusted in accordance with the residual limb in order to increase the effectiveness of load transmission between the prosthetic device and the residual limb [28]. The majority
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of research has been conducted on human skin invivo. In actual use, articial skins are tested exvivo and are distinct systems from the human body. The results of articial skin differ from those of real human skin, and neither their effectiveness nor clarity of comprehension are well established [28]. Tribological testing was done to evaluate the performance of a gelatin-based hydrogel patch that was intended to be positioned between the face area and the mask in a recent study. After Gelatin-Patch was rst tested, it became clear from the assay that the lm lacked the necessary resistance to keep its integrity when exposed to force, friction, and tem­perature [13].
A. Pal et al.
5.8 Impact ofSkin Care Products
Chemical treatments have an impact on the friction coefcient and skin moisture. Electrical impedance and amplitude/mean are two examples of parameters that may be useful for researching and contrasting lubricants, emollients, and moisturisers. Isopropyl alcohol lowers the friction coefcient while application of water increases the friction coefcient [24]. According to a study, occlusive substances (like petro­latum) raised electrical impedance and lowered amplitude/mean readings. Water and glycerine, for example, are directly hydrating agents that raise electrical imped­ance and amplitude/mean [24]. It was found that using powder substantially low­ered the friction coefcient by 50%. It was discovered that the static friction coefcient dropped when chalk was applied. Before beginning a climb, climbers may nd chalk helpful in drying their hands; however, any signs of chalk should be eliminated beforehand. According to a study, the oils eventually increase the skin’s friction coefcient after causing it to initially decrease [24]. According to a study, there were signicant quantitative differences between the three moisturisers, but they all had the same qualitative effect of raising friction and lowering electrical impedance. The effects of the high-performance cream were still discernible a day later, whereas the ordinary low-performance cream faded after less than an hour and the advanced cream persisted for many hours. For dermatological research, the repeatability and reproducibility of these ndings were within 10%, which is ade­quate. These tests quantify the functional quality of these creams and offer a scien­tic basis for their price [12].
5.9 Impact ofSkin Ageing
The topography of the human skin, as observed under a microscope, is made up of a network of lines whose arrangement reects the multidirectional tensions of col­lagen and elastic bres in the supercial dermis. This morphology exists from birth, and as people age, it becomes more pronounced in terms of both wavelength and
5 Tribological Measurements ofHuman Skin
163
depth until puberty [30]. The three layers of skin—the dermis, hypodermis, and epidermis—are signicantly impacted by the intricate process of skin ageing, both physically and functionally. The impact of ageing on the biomechanics of the der­mis and how this evolution may affect the reorganisation of the cutaneous lines that make up the skin relief are of special interest. There has been a claim made that the skin relief may represent the mechanical state of the skin underneath. However, there isn’t enough proof to say that there is a connection of this kind just yet [25]. A study examines the effects of ageing on skin morphology, elasticity, damping, loss factor, and tribology. The dynamic indentation demonstrates that as people age, their elasticity reduces and their loss factor rises. The integration of acoustic mea­surements with dynamic indentation provides a valuable aid in comprehending the importance of energy dissipation during friction. The impact of skin rheology and acoustic emission as a characteristic of ageing human skin is demonstrated in this paper [30]. A strong association has been noted between the mechanical qualities of the skin and its level of relief throughout the ageing process. As a result of ageing, there is a shift in mechanical properties—both topographical and mechanical— from nearly isotropic to anisotropic behaviour. Therefore, it would seem reasonable to say that the skin relief represents the mechanical conditions of the skin under­neath [25].

5.10 Future Scope

The future of skin tribology holds promising avenues for innovation and impact across diverse elds. Advancements in medical applications are anticipated, with potential breakthroughs in prosthetics, wearable medical devices, and biocompati­ble implants, driven by a deeper understanding of skin friction and wear. In the realm of cosmetics and personal care, the development of skincare and cosmetic products that minimise skin irritation through optimised tribological properties is on the horizon. Sports and apparel industries may witness improvements in perfor­mance fabrics and wearable sensors, enhancing comfort and monitoring skin condi­tions during physical activities. Materials science stands to benet from the creation of smart materials that dynamically adapt to skin conditions, while biomechanics and ergonomics may see advancements in human-machine interfaces and products designed with tribological considerations for improved user experience. As research methodologies evolve and testing techniques become more sophisticated, the estab­lishment of standardised approaches is likely, ensuring safety and compliance in products inuenced by skin tribology. The collaborative efforts of researchers, engi­neers, and industry professionals are poised to shape a future where skin tribology contributes signicantly to the development of innovative, comfortable, and user­friendly technologies and products.