Inhibition of thrombocyte aggregation

Dilatation of coronary vessels

44. A patient complains of frequent gingival haemorrhages he has been experiencing since his childhoo d. Blood test revealed a deficiency in blood-coagulation factor VIII. This means that the patient has an impairment of:

Thrombocyte aggregation

Thrombin generation

Thrombocyte adhesion

Prothrombinase generation

Fibrin generation

45. Examination of newborns in one of the Ukrainian cities revealed a baby with phenylketonuri a. The babys parents dont suffer from this disease and have two other healthy children. Specify the most likely parents genotype with phenylketonuria gene:

Аа х аа

Аа х Аа

Аа х АА

аа х аа

АА х аа

46. A patient with herpetic stomatitis was prescribed acyclovir for topical application. What is its mechanism of action?

It inhibits virus penetration into cells

It increases the resistance of macroorganism cells to the viruses

It inhibits synthesis of nucleic acids of viruses

It inhibits virion assembly

It inhibits virus maturation

47. A patient has a craniocerebral traum a. X-ray examination revealed a fracture of skull bas e. The fracture line passes through the spinous and round foramens. What bone is damaged?

Occipital

Frontal

Temporal

Sphenoid

Ethmoid

48. A 60-year-old male patient is unable to urinate after a surgery and needs a catheter installation. When a manipulator is not skilled enough, he can pierce the ureter in its following part (normally its the most narrow part):

Fossa navicularis

Pars prostatica

Ostium uretrae externum

Pars membranacea

Pars spongiosa

49. Autopsy of a 75-year-old patient who had been suffering from disseminated atherosclerosis and died under chronic cardiac failure revealed constriction and deformation of coronary arteries, tuberous intima whose section appeared to be white and petrosal. Specify the stage of atherosclerosis morphogenesis:

Liposclerosis

Bilipid

Lipoidosis

Atheromatosis

Atherocalcinosis

50. Examination of a 30-year-old mans mandible revealed in the region of his molar a dense tumour-like formation that significantly deformed the mandibl e. Here and there the formation wasnt fully detached from the bone tissu e. Microscopical examination of a tissue sampling revealed that stroma had some cords and follicles with odontogenous cylindric epithelial cells in peripheria and stellate cells resembling of the enamel oragan pulp in the centr e. What is the most likely diagnosis?

Osteoclastoma

Adenomatoid tumour

Primary intraosteal cancer

Adenocarcinoma

Ameloblastoma

51. After inoculation of feces sample into the 1% alkaline peptonic water and 8-hour incubation in the thermostat at a temperature of 37°C a culture in form of a tender bluish film has grown. Such cultural properties are typical for the causative agent of the following disease:

Typhoid fever

Dysentery

Plague

Paratyphoid fever A

Cholera

52. A 29-year-old female patient has moon face, upper body obesity, striae on her anterior abdominal wall, hirsutism; urine shows an increased rate of 17-oxy ketosteroids. What disease are these presentations typical for?